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Meptazinol Hydrochloride
Also known as: 59263-76-2, Meptazinol hcl, Meptazinol (hydrochloride), 3-(3-ethylhexahydro-1-methyl-1h-azepin-3-yl)phenol hydrochloride, Il-22811 hydrochloride, Wy-22811 hydrochloride
Molecular Formula
C15H24ClNO
Molecular Weight
269.81  g/mol
InChI Key
MPJUSISYVXABBH-UHFFFAOYSA-N
FDA UNII
T62FQ4ZCPA

A narcotic antagonist with analgesic properties. It is used for the control of moderate to severe pain.
1 2D Structure

Meptazinol Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-(3-ethyl-1-methylazepan-3-yl)phenol;hydrochloride
2.1.2 InChI
InChI=1S/C15H23NO.ClH/c1-3-15(9-4-5-10-16(2)12-15)13-7-6-8-14(17)11-13;/h6-8,11,17H,3-5,9-10,12H2,1-2H3;1H
2.1.3 InChI Key
MPJUSISYVXABBH-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCC1(CCCCN(C1)C)C2=CC(=CC=C2)O.Cl
2.2 Other Identifiers
2.2.1 UNII
T62FQ4ZCPA
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Meptazinol

2. Meptid

3. Wy 22811

4. Wy-22811

5. Wy22811

2.3.2 Depositor-Supplied Synonyms

1. 59263-76-2

2. Meptazinol Hcl

3. Meptazinol (hydrochloride)

4. 3-(3-ethylhexahydro-1-methyl-1h-azepin-3-yl)phenol Hydrochloride

5. Il-22811 Hydrochloride

6. Wy-22811 Hydrochloride

7. Meptid

8. Meptazinol Hydrochloride [usan]

9. Meptazinolhydrochloride

10. Il 22811 Hcl

11. Wy 22811 Hcl

12. Wy-22811

13. T62fq4zcpa

14. 3-(3-ethyl-1-methylazepan-3-yl)phenol Hydrochloride

15. 59263-76-2 (hcl)

16. Il-22811 Hcl

17. Wy-22811 Hcl

18. Il 22811

19. Dsstox_cid_25485

20. Dsstox_rid_80908

21. Dsstox_gsid_45485

22. Il-22811 Hydrochloride;wy-22811 Hydrochloride

23. 3-(3-ethyl-1-methylazepan-3-yl)phenol;hydrochloride

24. Meptazinol Hydrochloride (usan)

25. Einecs 261-683-0

26. Unii-t62fq4zcpa

27. Wy 22811

28. 3-(3-ethylhexahydro-1-methyl-1h-azepin-3-yl)-phenol Hydrochloride

29. M-(3-ethyl-1-methyl-hexahydro-1h-azepin-3-yl)phenol Hydrochloride

30. M-(3-ethylhexahydro-1-methyl-1h-azepin-3-yl)phenol Hydrochloride

31. Ncgc00016887-01

32. Phenol, 3-(3-ethylhexahydro-1-methyl-1h-azepin-3-yl)-, Hydrochloride

33. Phenol, M-(3-ethyl-1-methyl-hexahydro-1h-azepin-3-yl)-, Hydrochloride

34. Cas-59263-76-2

35. Mls002154094

36. Schembl124401

37. 3-(3-ethyl-1-methyl-azepan-3-yl)phenol Hydrochloride

38. Chembl1477274

39. Dtxsid3045485

40. Hms1571i09

41. Bcp12143

42. Tox21_110665

43. Hy-17467a

44. Meptazinol Hydrochloride [mi]

45. S3204

46. Akos015967029

47. Tox21_110665_1

48. Ac-1652

49. Ccg-221004

50. Cs-1813

51. Meptazinol Hydrochloride (+/-)

52. Meptazinol Hydrochloride [mart.]

53. Meptazinol Hydrochloride [who-dd]

54. Ncgc00179295-03

55. As-17434

56. Smr001233402

57. Ft-0649313

58. Sw197301-3

59. D04924

60. D81965

61. 263m762

62. A832231

63. Sr-01000838888

64. Sr-01000838888-2

65. 3-(3-ethyl-1-methyl-3-azepanyl)phenol Hydrochloride

66. Q27289714

67. Phenol, 3-(3-ethylhexahydro-1-methyl-1h-azepin-3-yl)-, Hydrochloride (1:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 269.81 g/mol
Molecular Formula C15H24ClNO
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass269.1546421 g/mol
Monoisotopic Mass269.1546421 g/mol
Topological Polar Surface Area23.5 Ų
Heavy Atom Count18
Formal Charge0
Complexity243
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Narcotics

Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS. (See all compounds classified as Narcotics.)


Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)


Narcotic Antagonists

Agents inhibiting the effect of narcotics on the central nervous system. (See all compounds classified as Narcotic Antagonists.)


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