Mepolizumab

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

2 API Suppliers, 2 Listed Suppliers

DEVELOPMENTS

10 Drug(s) in Development

10 Drug(s) in Development

DOSSIERs // Finished Dosage Formulations

21 Dossiers, 2 FDA Orange Book, 2 Europe, 3 Canada, 14 Australia

RELATED EXCIPIENT COMPANIES

Suppliers, 6 Seppic, 4 Gangwal Chemicals, 3 Actylis, 1 Nanjing Well Pharmaceutical, 1 DKSH, 1 BASF, 1 Jai Radhe Sales, 1 Pfanstiehl, 1 Nanjing Bold Chemical

EXCIPIENTS BY APPLICATIONS

10 Solubilizers, 5 Parenteral, 3 Taste Masking, 3 Coating Systems & Additives, 3 Emulsifying Agents, 3 Thickeners and Stabilizers, 3 Topical, 2 Surfactant & Foaming Agents, 1 Direct Compression, 1 Rheology Modifiers, 1 API Stability Enhancers, 1 Film Formers & Plasticizers, 1 Co-Processed Excipients

GLOBAL SALES INFORMATION

7 US Medicaid Prescriptions, 1 Finished Drug Prices

MARKET PLACE

1 APIs, 1 DOSSIERS // FDF

PATENTS

1 Health Canada Patents

1 Health Canada Patents

DIGITAL CONTENT

3 Data Compilations & Company Tracker #PharmaFlow, 74 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

325.00

Annual Reports

749.00

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as:

Molecular Formula

C₄₂H₆₆O₁₂

Molecular Weight

763.0 g/mol

InChI Key

PMOOKBAYUNEHOF-IKHMJLPLSA-N

1 2D Structure

Mepolizumab

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2S,3S,4S,5R,6R)-6-[[(4aR,6aR,6bS,8aS,14aR,14bR)-8a-carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,13,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-4-[(1R,2R,3S,4R)-2,3,4-trihydroxycyclohexyl]oxyoxane-2-carboxylic acid

2.1.2 InChI

InChI=1S/C42H66O12/c1-37(2)16-18-42(36(50)51)19-17-40(6)21(22(42)20-37)8-11-26-39(5)14-13-27(38(3,4)25(39)12-15-41(26,40)7)53-35-31(47)32(30(46)33(54-35)34(48)49)52-24-10-9-23(43)28(44)29(24)45/h23-33,35,43-47H,8-20H2,1-7H3,(H,48,49)(H,50,51)/t23-,24-,25+,26-,27?,28+,29+,30+,31-,32+,33+,35-,39+,40-,41-,42+/m1/s1

2.1.3 InChI Key

PMOOKBAYUNEHOF-IKHMJLPLSA-N

2.1.4 Canonical SMILES

CC1(CCC2(CCC3(C(=C2C1)CCC4C3(CCC5C4(CCC(C5(C)C)OC6C(C(C(C(O6)C(=O)O)O)OC7CCC(C(C7O)O)O)O)C)C)C)C(=O)O)C

2.1.5 Isomeric SMILES

C[C@]12CCC(C([C@@H]1CC[C@@]3([C@@H]2CCC4=C5CC(CC[C@@]5(CC[C@]43C)C(=O)O)(C)C)C)(C)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O[C@@H]7CC[C@H]([C@@H]([C@H]7O)O)O)O

2.2 Create Date

2012-02-15

3 Chemical and Physical Properties

Molecular Formula	C₄₂H₆₆O₁₂
Molecular Weight	763.0 g/mol
XLogP3	5.1
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	6
Exact Mass	762.45542754 g/mol
Monoisotopic Mass	762.45542754 g/mol
Topological Polar Surface Area	203 Å²
Heavy Atom Count	54
Formal Charge	0
Complexity	1530
Isotope Atom Count	0
Defined Atom Stereocenter Count	15
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

Find Mepolizumab manufacturers, exporters & distributors on PharmaCompass

Mepolizumab

Mepolizumab

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

2 API Suppliers

2 Listed Suppliers

DEVELOPMENTS

10 Drug(s) in Development

DOSSIERs // Finished Dosage Formulations

21 Dossiers

2 FDA Orange Book

2 Europe

3 Canada

14 Australia

RELATED EXCIPIENT COMPANIES

Suppliers

6 Seppic

4 Gangwal Chemicals

3 Actylis

1 Nanjing Well Pharmaceutical

1 DKSH

1 BASF

1 Jai Radhe Sales

1 Pfanstiehl

1 Nanjing Bold Chemical

EXCIPIENTS BY APPLICATIONS

10 Solubilizers

5 Parenteral

3 Taste Masking

3 Coating Systems & Additives

3 Emulsifying Agents

3 Thickeners and Stabilizers

3 Topical

2 Surfactant & Foaming Agents

1 Direct Compression

1 Rheology Modifiers

1 API Stability Enhancers

1 Film Formers & Plasticizers

1 Co-Processed Excipients

GLOBAL SALES INFORMATION

7 US Medicaid Prescriptions

1 Finished Drug Prices

MARKET PLACE

1 APIs

1 DOSSIERS // FDF

PATENTS

1 Health Canada Patents

DIGITAL CONTENT

3 Data Compilations & Company Tracker #PharmaFlow

74 News

API SUPPLIERS

API REF. PRICE (USD / KG)

INTERMEDIATES

DOSSIERS // FDF

GLOBAL SALES (USD Million)

EXCIPIENTS

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

REF STANDARD

SERVICES

What are you looking for?