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Chemistry

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Also known as: 595-33-5, Megace, Megace es, Niagestin, Megestryl acetate, Megeron
Molecular Formula
C24H32O4
Molecular Weight
384.5  g/mol
InChI Key
RQZAXGRLVPAYTJ-GQFGMJRRSA-N
FDA UNII
TJ2M0FR8ES

Megestrol Acetate
Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
1 2D Structure

Megestrol Acetate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
2.1.2 InChI
InChI=1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1
2.1.3 InChI Key
RQZAXGRLVPAYTJ-GQFGMJRRSA-N
2.1.4 Canonical SMILES
CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C
2.1.5 Isomeric SMILES
CC1=C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)OC(=O)C)C)[C@@]4(C1=CC(=O)CC4)C
2.2 Other Identifiers
2.2.1 UNII
TJ2M0FR8ES
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Acetate, Megestrol

2. Apo Megestrol

3. Apo-megestrol

4. Apomegestrol

5. Borea

6. Lin Megestrol

7. Lin-megestrol

8. Linmegestrol

9. Maygace

10. Megace

11. Megefren

12. Megestat

13. Megostat

14. Mestrel

15. Nu Megestrol

16. Nu-megestrol

17. Numegestrol

2.3.2 Depositor-Supplied Synonyms

1. 595-33-5

2. Megace

3. Megace Es

4. Niagestin

5. Megestryl Acetate

6. Megeron

7. Megestat

8. Ovaban

9. Ovarid

10. Maygace

11. Pallace

12. Bdh 1298

13. Magestin

14. Sc 10363

15. Nsc-71423

16. Volidan

17. Sc10363

18. 17alpha-hydroxy-6-methylpregna-4,6-diene-3,20-dione Acetate

19. Megesterol Acetate

20. 17alpha-acetoxy-6-dehydro-6-methylprogesterone

21. 6-dehydro-6-methyl-17alpha-acetoxyprogesterone

22. 6-methyl-6-dehydro-17alpha-acetoxyprogesterone

23. 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate

24. 17-acetoxy-6-methylpregna-4,6-diene-3,20-dione

25. Sc-10363

26. 17-(acetyloxy)-6-methylpregna-4,6-diene-3,20-dione

27. Bdh-1298

28. 6-methyl-17alpha-hydroxy-delta(sup 6)-progesterone Acetate

29. Tj2m0fr8es

30. [(8r,9s,10r,13s,14s,17r)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1h-cyclopenta[a]phenanthren-17-yl] Acetate

31. Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-

32. 6-methyl-3,20-dioxopregna-4,6-dien-17-yl Acetate

33. Megestrol 17.alpha.-acetate

34. Mls000028633

35. 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione Acetate

36. Bdh1298

37. Smr000058691

38. Dsstox_cid_20683

39. Dsstox_rid_79539

40. Dsstox_gsid_40683

41. Megestil

42. 6-methyl-17alpha-acetoxypregna-4,6-diene-3,20-dione

43. Ovaban (veterinary)

44. 6-methyl-delta(sup 6)-dehydro-17alpha-acetoxyprogesterone

45. Megestrolacetate

46. 6-methyl-delta(sup 4,6)-pregnadien-17alpha-ol-3,20-dione Acetate

47. Megestrol Acetate [usan]

48. (8xi,9xi,10xi,13xi,14xi)-6-methyl-3,20-dioxopregna-4,6-dien-17-yl Acetate

49. Ccris 372

50. Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-, Acetate

51. Megestrol-17-acetate

52. Einecs 209-864-5

53. Unii-tj2m0fr8es

54. Megestin

55. Megestrol Acetole [progestins]

56. Megestrol Acetate [usan:usp]

57. Megestrol Acetole

58. Megestrol-acetate

59. 17-alpha-acetoxy-6-dehydro-6-methylprogesterone

60. 6-dehydro-6-methyl-17-alpha-acetoxyprogesterone

61. 6-methyl-6-dehydro-17-alpha-acetoxyprogesterone

62. Ncgc00016516-01

63. (8r,9s,10r,13s,14s,17r)-17-acetyl-6,10,13-trimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-17-yl Acetate

64. Cas-595-33-5

65. Megace (tn)

66. 17alpha-acetoxy-6-methylpregna-4,6-diene-3,20-dione

67. 6-methyl-17-alpha-acetoxypregna-4,6-diene-3,20-dione

68. 6-methyl-17-alpha-hydroxy-delta(sup 6)-progesterone Acetate

69. 6-methyl-6-dehydro-17.alpha.-acetylprogesterone

70. 6-methyl-delta(sup 6)-dehydro-17-alpha-acetoxyprogesterone

71. 6-methyl-delta4,6-pregnadien-17alpha-ol-3,20-dione Acetate

72. 17.alpha.-acetoxy-6-dehydro-6-methylprogesterone

73. 6-dehydro-6-methyl-17.alpha.-acetoxyprogesterone

74. 6-methyl-6-dehydro-17.alpha.-acetoxyprogesterone

75. Megestrol Acetate (usp)

76. Opera_id_1511

77. Prestwick0_000956

78. Prestwick1_000956

79. Prestwick2_000956

80. Prestwick3_000956

81. 6-methyl-delta(sup 4,6)-pregnadien-17-alpha-ol-3,20-dione Acetate

82. Schembl745

83. Bspbio_000952

84. Mls000759501

85. Mls001074091

86. Mls001424055

87. Par-100,2

88. Spbio_003101

89. Megestrol Acetate [mi]

90. Bpbio1_001048

91. Chebi:6723

92. Chembl1201139

93. Dtxsid9040683

94. Megestrol Acetate [vandf]

95. Megestrol Acetate [mart.]

96. Bcpp000168

97. Hms1570p14

98. Hms2051i20

99. Hms2090n04

100. Hms2097p14

101. Hms2235d16

102. Hms3714p14

103. Megestrol Acetate [usp-rs]

104. Megestrol Acetate [who-dd]

105. Megestrol Acetate [who-ip]

106. Nia

107. Nsc71423

108. Zinc4097467

109. Tox21_110469

110. Tox21_302360

111. Lmst02030118

112. Mfcd00056470

113. S1304

114. Akos015894927

115. Megestrol Acetate [green Book]

116. Tox21_110469_1

117. Bcp9000904

118. Ccg-100899

119. Cs-2065

120. Db00351

121. Megestrol Acetate [orange Book]

122. Nc00149

123. Megestrol Acetate [ep Monograph]

124. 17-acetoxy-6-methylpregna-4,20-dione

125. Megestrol Acetate [usp Monograph]

126. Ncgc00024196-03

127. Ncgc00024196-05

128. Ncgc00255456-01

129. Ac-24570

130. As-13384

131. Hy-13676

132. 17.alpha.-acetoxy-6-methyl-4,20-dione

133. Ab00490013

134. B1377

135. 17-hydroxy-6-methylpregna-4,20-dione Acetate

136. 17.alpha.-acetoxy-6-methylpregna-4,20-dione

137. C08151

138. D00952

139. D91560

140. Ab00383046-13

141. Ab00383046-14

142. Ab00383046-15

143. Ab00383046_16

144. Pregna-4,20-dione, 17-(acetyloxy)-6-methyl-

145. 595m335

146. A832354

147. Megestrol-17-acetate 1000 Microg/ml In Methanol

148. Sr-01000000258

149. Megestrol-17-acetate 100 Microg/ml In Acetonitrile

150. Pregna-4,20-dione, 17-hydroxy-6-methyl-, Acetate

151. Q-201346

152. Q6808975

153. Sr-01000000258-4

154. Brd-k19507340-001-03-1

155. Medroxyprogesterone Acetate Impurity G [who-ip]

156. Megestrol Acetate, Vetranal(tm), Analytical Standard

157. Megestrol-17-acetate 100 Microg/ml In Methanol/water

158. 17alpha-acetoxy-6-methyl-4,6-pregnadiene-3,20-dione

159. Megestrol Acetate, Analytical Standard, For Drug Analysis

160. Medroxyprogesterone Acetate Impurity G [ep Impurity]

161. Wln: L E5 B666 Ov Ku Mutj A1 E1 Fv1 Fov1 L1

162. 6-methyl-17.alpha.-hydroxy-.delta.(sup 6)-progesterone Acetate

163. Megestrol Acetate, European Pharmacopoeia (ep) Reference Standard

164. 6-methyl-3,20-dioxopregna-4,6-dien-17-yl Acetate [who-ip]

165. Megestrol Acetate, United States Pharmacopeia (usp) Reference Standard

166. Megesgtrol Acetate, Pharmaceutical Secondary Standard; Certified Reference Material

167. Megestrol Acetate For Peak Identification, European Pharmacopoeia (ep) Reference Standard

168. Megestrol Acetate For System Suitability, European Pharmacopoeia (ep) Reference Standard

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 384.5 g/mol
Molecular Formula C24H32O4
XLogP33.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass384.23005950 g/mol
Monoisotopic Mass384.23005950 g/mol
Topological Polar Surface Area60.4 Ų
Heavy Atom Count28
Formal Charge0
Complexity821
Isotope Atom Count0
Defined Atom Stereocenter Count6
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameMegace
PubMed HealthMegestrol Acetate (By mouth)
Drug ClassesEndocrine-Metabolic Agent
Drug LabelMEGACE (megestrol acetate, USP) Oral Suspension contains megestrol acetate, a synthetic derivative of the naturally occurring steroid hormone, progesterone. Megestrol acetate is a white, crystalline solid chemically designated as 17-(acetyloxy)-6...
Active IngredientMegestrol acetate
Dosage FormSuspension
RouteOral
Strength40mg/ml
Market StatusPrescription
CompanyBristol Myers Squibb

2 of 6  
Drug NameMegace es
PubMed HealthMegestrol Acetate (By mouth)
Drug ClassesEndocrine-Metabolic Agent
Drug LabelMegace ES oral suspension contains megestrol acetate, a synthetic derivative of the naturally occurring steroid hormone, progesterone. Megestrol acetate is a white, crystalline solid chemically designated as 17-Hydroxy-6-methyl pregna-4,6-diene-3...
Active IngredientMegestrol acetate
Dosage FormSuspension
RouteOral
Strength125mg/ml
Market StatusPrescription
CompanyPar Pharm

3 of 6  
Drug NameMegestrol acetate
PubMed HealthMegestrol Acetate (By mouth)
Drug ClassesEndocrine-Metabolic Agent
Drug LabelMegestrol acetate is a synthetic, antineoplastic and progestational drug. Megestrol acetate is a white, crystalline solid chemically designated as 17(alpha)-(acetyloxy)-6-methylpregna-4,6-diene-3,20-dione. Solubility at 37C in water is 2 mcg per mL...
Active IngredientMegestrol acetate
Dosage FormTablet; Suspension
RouteOral
Strength125mg/ml; 40mg/ml; 40mg; 20mg
Market StatusPrescription
CompanyTwi Pharms; Wockhardt; Par Pharm; Roxane; Teva Pharms; Barr

4 of 6  
Drug NameMegace
PubMed HealthMegestrol Acetate (By mouth)
Drug ClassesEndocrine-Metabolic Agent
Drug LabelMEGACE (megestrol acetate, USP) Oral Suspension contains megestrol acetate, a synthetic derivative of the naturally occurring steroid hormone, progesterone. Megestrol acetate is a white, crystalline solid chemically designated as 17-(acetyloxy)-6...
Active IngredientMegestrol acetate
Dosage FormSuspension
RouteOral
Strength40mg/ml
Market StatusPrescription
CompanyBristol Myers Squibb

5 of 6  
Drug NameMegace es
PubMed HealthMegestrol Acetate (By mouth)
Drug ClassesEndocrine-Metabolic Agent
Drug LabelMegace ES oral suspension contains megestrol acetate, a synthetic derivative of the naturally occurring steroid hormone, progesterone. Megestrol acetate is a white, crystalline solid chemically designated as 17-Hydroxy-6-methyl pregna-4,6-diene-3...
Active IngredientMegestrol acetate
Dosage FormSuspension
RouteOral
Strength125mg/ml
Market StatusPrescription
CompanyPar Pharm

6 of 6  
Drug NameMegestrol acetate
PubMed HealthMegestrol Acetate (By mouth)
Drug ClassesEndocrine-Metabolic Agent
Drug LabelMegestrol acetate is a synthetic, antineoplastic and progestational drug. Megestrol acetate is a white, crystalline solid chemically designated as 17(alpha)-(acetyloxy)-6-methylpregna-4,6-diene-3,20-dione. Solubility at 37C in water is 2 mcg per mL...
Active IngredientMegestrol acetate
Dosage FormTablet; Suspension
RouteOral
Strength125mg/ml; 40mg/ml; 40mg; 20mg
Market StatusPrescription
CompanyTwi Pharms; Wockhardt; Par Pharm; Roxane; Teva Pharms; Barr

4.2 Drug Indication

For the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used for the palliative management of recurrent, inoperable, or metastatic breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.


FDA Label


5 Pharmacology and Biochemistry
5.1 Pharmacology

Megestrol is a synthetic progestin and has the same physiologic effects as natural progesterone. These effects include induction of secretory changes in the endometrium, increase in basal body temperature, pituitary inhibition, and production of withdrawal bleeding in the presence of estrogen. Mestrogel has slight glucocorticoid activity and very slight mineralocorticoid activity. This drug has no estrogenic, androgenic, or anabolic activity. The precise mechanism of megestrol’s antianorexic and anticachetic effects is unknown. Initially developed as a contraceptive, it was first evaluated in breast cancer treatment in 1967.


5.2 MeSH Pharmacological Classification

Antineoplastic Agents, Hormonal

Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079) (See all compounds classified as Antineoplastic Agents, Hormonal.)


Appetite Stimulants

Agents that are used to stimulate appetite. These drugs are frequently used to treat anorexia associated with cancer and AIDS. (See all compounds classified as Appetite Stimulants.)


5.3 FDA Pharmacological Classification
5.3.1 Pharmacological Classes
Progestin [EPC]; Progesterone Congeners [CS]
5.4 Absorption, Distribution and Excretion

Absorption

Variable, but well absorbed orally.


Route of Elimination

The major route of drug elimination in humans is urine. Respiratory excretion as labeled carbon dioxide and fat storage may have accounted for at least part of the radioactivity not found in urine and feces.


5.5 Metabolism/Metabolites

Primarily hepatic. Megestrol metabolites which were identified in urine constituted 5% to 8% of the dose administered. Respiratory excretion as labeled carbon dioxide and fat storage may have accounted for at least part of the radioactivity not found in urine and feces. No active metabolites have been identified.


5.6 Biological Half-Life

34 hours


5.7 Mechanism of Action

The precise mechanism by which megestrol acetate produces effects in anorexia and cachexia is unknown at the present time, but its progestin antitumour activity may involve suppression of luteinizing hormone by inhibition of pituitary function. Studies also suggest that the megestrol's weight gain effect is related to its appetite-stimulant or metabolic effects rather than its glucocorticoid-like effects or the production of edema. It has also been suggested that megestrol may alter metabolic pathyways via interferences with the production or action of mediators such as cachectin, a hormone that inhibits adipocyte lipogenic enzymes.


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DE AMICIS-47 20123 MILANO Italy","customerAddress":"564\/A\/22, ROAD NO.92"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1712341800,"product":"NOMEGESTROL ACETATE (BATCH NO.NE0732)","address":"","city":"","supplier":"NEW CHEM S P A","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"SENADOR LABORATORIES PRIVATE LTD","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"14186.7","totalValueFC":"71649.4","currency":"USD","unitRateINR":"1196650","date":"06-Apr-2024","totalValueINR":"5983250","totalValueInUsd":"71649.4","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29372300","bill_no":"1001291","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"VIA E. DE AMICIS-47 20123 MILANO Italy","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722623400,"product":"NOMEGESTROL ACETATE (FOR R&D PURPOSE ONLY NOT FOR SALE VIDEIMPORT LIC.NO.SW\/OD\/11\/2024\/000003184 DT. 24.06.2024)","address":"D-158-A,OKHLA INDUSTRIAL AREA,","city":"NEW DELHI","supplier":"NEWCHEM S P A","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"KUSUM HEALTHCARE PRIVATE LTD","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"19800","totalValueFC":"2177.6","currency":"EURO","unitRateINR":"1826550","date":"03-Aug-2024","totalValueINR":"182655","totalValueInUsd":"2177.6","indian_port":"Delhi Air","hs_no":"29372300","bill_no":"4856876","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"VIA SAN VITTORE 39 - 20123, MILANO,ITALYSDNF ITALY","customerAddress":"D-158-A,OKHLA INDUSTRIAL AREA,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1733941800,"product":"NOMEGESTROL ACETATE (FOR R&D PURPOSE ONLY NOT FOR SALE VIDEIMPORT LIC.NO.SW\/OD\/11\/2024\/000003184 DT. 24.06.2024)NOMEGESTROL ACETATE (FOR R &D PURPOSE ONLY NOT FOR SALE VIDE","address":"D-158-A,OKHLA INDUSTRIAL AREA,","city":"NEW DELHI","supplier":"NEWCHEM S P A","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"KUSUM HEALTHCARE PRIVATE LTD","customerCountry":"INDIA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"21002.1","totalValueFC":"2117","currency":"USD","unitRateINR":"1798830","date":"12-Dec-2024","totalValueINR":"179883","totalValueInUsd":"2117","indian_port":"Delhi Air","hs_no":"29372300","bill_no":"7189607","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"VIA SAN VITTORE 39 - 20123, MILANO, ITALY SDNF ITALY","customerAddress":"D-158-A,OKHLA INDUSTRIAL AREA,"}]
09-Nov-2023
07-Jun-2025
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

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API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

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Drugs in Development

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Details:

Megestrol Acetate is a small molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Cancer Cachexia.


Lead Product(s): Megestrol Acetate,Inapplicable

Therapeutic Area: Nutrition and Weight Loss Brand Name: Undisclosed

Study Phase: Phase IVProduct Type: Miscellaneous

Sponsor: Henan Cancer Hospital

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable November 21, 2025

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01

BIO Partnering at JPM
Not Confirmed
BIO Partnering at JPM
Not Confirmed

Details : Megestrol Acetate is a small molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Cancer Cachexia.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

November 21, 2025

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Details:

Megestrol Acetate is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Carcinoma, Non-Small-Cell Lung.


Lead Product(s): Megestrol Acetate,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: Tongji Hospital

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 02, 2025

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02

BIO Partnering at JPM
Not Confirmed
BIO Partnering at JPM
Not Confirmed

Details : Megestrol Acetate is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Carcinoma, Non-Small-Cell Lung.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

September 02, 2025

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Details:

Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Nausea.


Lead Product(s): Megestrol Acetate,Inapplicable

Therapeutic Area: Gastroenterology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable August 19, 2025

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03

BIO Partnering at JPM
Not Confirmed
BIO Partnering at JPM
Not Confirmed

Details : Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Nausea.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

August 19, 2025

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Details:

MK-5684 is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Neoplasms.


Lead Product(s): MK-5684,Fludrocortisone Acetate,Dexamethasone,Hydrocortisone,Fulvestrant,Exemestane,Megestrol Acetate,Medroxyprogesterone Acetate,Tamoxifen Citrate,

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable May 20, 2025

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04

Merck & Co

U.S.A
arrow
BIO Partnering at JPM
Not Confirmed

Merck & Co

U.S.A
arrow
BIO Partnering at JPM
Not Confirmed

Details : MK-5684 is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

May 20, 2025

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Details:

Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Carcinoma, Non-Small-Cell Lung.


Lead Product(s): Megestrol Acetate,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: Wuhan Union Hospital

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable May 07, 2025

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05

BIO Partnering at JPM
Not Confirmed
BIO Partnering at JPM
Not Confirmed

Lead Product(s) : Megestrol Acetate,Inapplicable

Therapeutic Area : Oncology

Highest Development Status : Phase III

Partner/Sponsor/Collaborator : Wuhan Union Hospital

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Carcinoma, Non-Small-Cell Lung.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

May 07, 2025

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Details:

Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Small Cell Lung Carcinoma.


Lead Product(s): Megestrol Acetate,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: West China Hospital

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable May 07, 2025

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06

BIO Partnering at JPM
Not Confirmed
BIO Partnering at JPM
Not Confirmed

Lead Product(s) : Megestrol Acetate,Inapplicable

Therapeutic Area : Oncology

Highest Development Status : Phase III

Partner/Sponsor/Collaborator : West China Hospital

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Small Cell Lung Carcinoma.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

May 07, 2025

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Details:

Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Fatigue-associated with Neoplasms.


Lead Product(s): Megestrol Acetate,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: UndisclosedProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 17, 2025

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07

BIO Partnering at JPM
Not Confirmed
BIO Partnering at JPM
Not Confirmed

Details : Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Fatigue-associated with Neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

February 17, 2025

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Details:

Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Squamous Cell Carcinoma of Head and Neck.


Lead Product(s): Megestrol Acetate,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable January 13, 2025

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08

BIO Partnering at JPM
Not Confirmed
BIO Partnering at JPM
Not Confirmed

Details : Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Squamous Cell Carcinoma of Head and Neck.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

January 13, 2025

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  • Development Update

Details:

Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Endometrial Neoplasms.


Lead Product(s): Megestrol Acetate,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Sponsor: Ontario Institute for Cancer Research

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable April 18, 2022

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09

Sunnybrook Health Sciences Centre

Country
arrow
BIO Partnering at JPM
Not Confirmed

Sunnybrook Health Sciences Centre

Country
arrow
BIO Partnering at JPM
Not Confirmed

Lead Product(s) : Megestrol Acetate,Inapplicable

Therapeutic Area : Oncology

Highest Development Status : Phase I

Partner/Sponsor/Collaborator : Ontario Institute for Cancer Research

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Endometrial Neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

April 18, 2022

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Details:

Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Head and Neck Neoplasms.


Lead Product(s): Megestrol Acetate,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Miscellaneous

Sponsor: Chang Gung Memorial Hospital

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable December 02, 2016

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10

BIO Partnering at JPM
Not Confirmed
BIO Partnering at JPM
Not Confirmed

Lead Product(s) : Megestrol Acetate,Inapplicable

Therapeutic Area : Oncology

Highest Development Status : Phase II

Partner/Sponsor/Collaborator : Chang Gung Memorial Hospital

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Megestrol Acetate is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Head and Neck Neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

December 02, 2016

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INTERMEDIATE SUPPLIERS

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothPfizer CentreOne is a global CDMO and a leading supplier of Specialty APIs.

CAS Number : 71-58-9

End Use API : Megestrol Acetate

About The Company : Pfizer CentreOne® is an altogether different global contract development and manufacturing organization (CDMO), and a leading supplier of specialty APIs and in...

Pfizer centreOne
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FDA Orange Book

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSynergice, a Strides Pharma initiative, is a new gen B2B platform for diverse portofolio needs.

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RLD : No

TE Code : AB

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : TABLET;ORAL

Dosage Strength : 20MG

Approval Date : 1988-08-08

Application Number : 72422

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

Strides Pharma Science

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSynergice, a Strides Pharma initiative, is a new gen B2B platform for diverse portofolio needs.

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Digital Content Digital Content

RLD : No

TE Code : AB

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : TABLET;ORAL

Dosage Strength : 40MG

Approval Date : 1988-08-08

Application Number : 72423

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

Strides Pharma Science

03

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSynergice, a Strides Pharma initiative, is a new gen B2B platform for diverse portofolio needs.

Flag India
Digital Content Digital Content

RLD : No

TE Code : AB

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : SUSPENSION;ORAL

Dosage Strength : 40MG/ML

Approval Date : 2001-07-25

Application Number : 75671

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

Strides Pharma Science

04

BARR

U.S.A
BIO Partnering at JPM
Not Confirmed
arrow

BARR

U.S.A
arrow
BIO Partnering at JPM
Not Confirmed

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : TABLET;ORAL

Dosage Strength : 40MG

Approval Date : 1995-11-30

Application Number : 74621

RX/OTC/DISCN : RX

RLD : No

TE Code : AB

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05

CHARTWELL

U.S.A
BIO Partnering at JPM
Not Confirmed
arrow

CHARTWELL

U.S.A
arrow
BIO Partnering at JPM
Not Confirmed

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : SUSPENSION;ORAL

Dosage Strength : 125MG/ML

Approval Date : 2017-12-01

Application Number : 204688

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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06

HIKMA

United Kingdom
BIO Partnering at JPM
Not Confirmed
arrow

HIKMA

United Kingdom
arrow
BIO Partnering at JPM
Not Confirmed

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : TABLET;ORAL

Dosage Strength : 20MG

Approval Date : 1995-09-29

Application Number : 74458

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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07

HIKMA

United Kingdom
BIO Partnering at JPM
Not Confirmed
arrow

HIKMA

United Kingdom
arrow
BIO Partnering at JPM
Not Confirmed

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : TABLET;ORAL

Dosage Strength : 40MG

Approval Date : 1995-09-29

Application Number : 74458

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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08

HIKMA

United Kingdom
BIO Partnering at JPM
Not Confirmed
arrow

HIKMA

United Kingdom
arrow
BIO Partnering at JPM
Not Confirmed

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : SUSPENSION;ORAL

Dosage Strength : 40MG/ML

Approval Date : 2017-06-09

Application Number : 203960

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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09

TWI PHARMS

Taiwan
BIO Partnering at JPM
Not Confirmed
arrow

TWI PHARMS

Taiwan
arrow
BIO Partnering at JPM
Not Confirmed

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : SUSPENSION;ORAL

Dosage Strength : 125MG/ML

Approval Date : 2014-08-27

Application Number : 203139

RX/OTC/DISCN : RX

RLD : No

TE Code :

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10

USL PHARMA

United Kingdom
BIO Partnering at JPM
Not Confirmed
arrow

USL PHARMA

United Kingdom
arrow
BIO Partnering at JPM
Not Confirmed

MEGESTROL ACETATE

Brand Name : MEGESTROL ACETATE

Dosage Form : TABLET;ORAL

Dosage Strength : 20MG

Approval Date : 1987-10-02

Application Number : 70646

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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Europe

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01

BIO Partnering at JPM
Not Confirmed
arrow
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BIO Partnering at JPM
Not Confirmed

Megestrol Acetate

Brand Name : Megace

Dosage Form : Tablet

Dosage Strength : 160mg

Packaging :

Approval Date : 04/11/2004

Application Number : 20040916000446

Regulatory Info : Deregistered

Registration Country : Sweden

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02

Orifarm Ab

Denmark
BIO Partnering at JPM
Not Confirmed
arrow

Orifarm Ab

Denmark
arrow
BIO Partnering at JPM
Not Confirmed

Megestrol Acetate

Brand Name : Megace

Dosage Form : Tablet

Dosage Strength : 160mg

Packaging :

Approval Date : 17/11/2004

Application Number : 20040916001023

Regulatory Info : Deregistered

Registration Country : Sweden

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03

Pharmacenter

Hungary
BIO Partnering at JPM
Not Confirmed
arrow

Pharmacenter

Hungary
arrow
BIO Partnering at JPM
Not Confirmed

Megestrol Acetate

Brand Name :

Dosage Form : Tablet

Dosage Strength : 160MG

Packaging : 30 Tabs & 100 Tabs

Approval Date :

Application Number :

Regulatory Info : EU CTD Dossier Available

Registration Country : Hungary

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04

BIO Partnering at JPM
Not Confirmed
arrow
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BIO Partnering at JPM
Not Confirmed

Megestrol

Brand Name : MEGEXIA

Dosage Form : Tablets

Dosage Strength : 160 mg

Packaging : 30 UNITS 160 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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05

BIO Partnering at JPM
Not Confirmed
arrow
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BIO Partnering at JPM
Not Confirmed

Megestrol Acetate

Brand Name : Borea

Dosage Form : Tablet

Dosage Strength : 160MG

Packaging :

Approval Date : 1991-07-01

Application Number : 58775

Regulatory Info : Authorized

Registration Country : Spain

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06

BIO Partnering at JPM
Not Confirmed
arrow
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BIO Partnering at JPM
Not Confirmed

Megestrol Acetate

Brand Name : Borea

Dosage Form : Granule For Oral Suspension

Dosage Strength : 160MG

Packaging :

Approval Date : 1998-07-01

Application Number : 62011

Regulatory Info : Authorized

Registration Country : Spain

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07

TEOFARMA Srl

Country
BIO Partnering at JPM
Not Confirmed
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TEOFARMA Srl

Country
arrow
BIO Partnering at JPM
Not Confirmed

Megestrol Acetate

Brand Name : Megestil

Dosage Form : Megestrol 160Mg 30 Joined' Oral Use

Dosage Strength : 30 CPR 160 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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08

PHARMASWISS CESKA REPUBL.S.R.O

Country
BIO Partnering at JPM
Not Confirmed
arrow

PHARMASWISS CESKA REPUBL.S.R.O

Country
arrow
BIO Partnering at JPM
Not Confirmed

Megestrol Acetate

Brand Name : Megace@

Dosage Form : Megestrol 160Mg 30 Joined' Oral Use

Dosage Strength : 30 CPR 160 mg

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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09

Pharma Swiss Ceska republika s.r.o.

Country
BIO Partnering at JPM
Not Confirmed
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Pharma Swiss Ceska republika s.r.o.

Country
arrow
BIO Partnering at JPM
Not Confirmed

Megestrol Acetate

Brand Name : Megace

Dosage Form : Antic-calc Tablet

Dosage Strength : 160 mg

Packaging : Blister

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Norway

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10

ISTITUTO GENTILI SRL

Country
BIO Partnering at JPM
Not Confirmed
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ISTITUTO GENTILI SRL

Country
arrow
BIO Partnering at JPM
Not Confirmed

Megestrol

Brand Name : GESTROLTEX

Dosage Form : Tablets

Dosage Strength : 160 mg

Packaging : 30 UNITS 160 MG - ORAL USE

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Italy

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Listed Dossiers

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01

  • fda
  • EDQM
  • WHO-GMP

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Digital Content Digital Content

Regulatory Info :

Registration Country : India

Megestrol Acetate

Brand Name : Megestrol Acetate

Dosage Form : Tablet

Dosage Strength : 20MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Strides Pharma Science

01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothSynergice, a Strides Pharma initiative, is a new gen B2B platform for diverse portofolio needs.

Flag India
Digital Content Digital Content

Packaging :

Regulatory Info :

Megestrol Acetate

Dosage : Tablet

Dosage Strength : 20MG

Brand Name : Megestrol Acetate

Approval Date :

Application Number :

Registration Country : India

Strides Pharma Science

02

  • fda
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  • WHO-GMP

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Regulatory Info :

Registration Country : India

Megestrol Acetate

Brand Name : Megestrol Acetate

Dosage Form : Tablet

Dosage Strength : 40MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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Packaging :

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Megestrol Acetate

Dosage : Tablet

Dosage Strength : 40MG

Brand Name : Megestrol Acetate

Approval Date :

Application Number :

Registration Country : India

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Megestrol Acetate

Brand Name : Megestrol Acetate

Dosage Form : Oral Solution

Dosage Strength : 40MG/ML

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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Megestrol Acetate

Dosage : Oral Solution

Dosage Strength : 40MG/ML

Brand Name : Megestrol Acetate

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Registration Country : India

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Megestrol Acetate

Brand Name : MEGETRA

Dosage Form : Tablet

Dosage Strength : 40MG

Packaging : 1X10 Tablets

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

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Brand Name : MEGETRA

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Registration Country : India

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Registration Country : India

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Megestrol Acetate

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Registration Country : India

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Registration Country : India

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Registration Country : India

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Registration Country : India

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Registration Country : India

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Megestrol Acetate

Brand Name : MESTROL

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Registration Country : India

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Megestrol Acetate

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Registration Country : China

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DOSAGE - SUSPENSION;ORAL - 40MG/ML **Federal ...DOSAGE - SUSPENSION;ORAL - 40MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

USFDA APPLICATION NUMBER - 20264

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DOSAGE - SUSPENSION;ORAL - 125MG/ML

USFDA APPLICATION NUMBER - 21778

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Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

Grade : Oral

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Brand Name : Starlose®

Excipient Details : Starlose P40 (Starch & Lactose Monohydrate) is used as a diluent in oral dosage forms such as tablets.

Pharmacopoeia Ref : DMF, EXCiPAT, KOSHER, HALAL, W...

Technical Specs : NA

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Virtual BoothNanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.

Grade : Parenteral

Category : Parenteral

Brand Name : Lactose Monohydrate

Excipient Details : Lactose monohydrate is used as a diluent in inhalation and lyophilized preparations.

Pharmacopoeia Ref : ChP/USP/EP/JP

Technical Specs : NA

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Virtual BoothGangwal Healthcare is powered by innovation, driving health, wellness & healing.

Grade : Oral

Category : Co-Processed Excipients, Fillers, Diluents & Binders

Brand Name : Microlose™

Excipient Details : Microlose (Lactose Monohydrate & Microcrystalline Cellulose) is used as a diluent in oral dosage forms such as tablets.

Pharmacopoeia Ref : DMF, EXCiPAT, KOSHER, HALAL, W...

Technical Specs : Lactose Monohydrate – 40%, Microcrystalline cellulose – 60%

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https://www.pharmacompass.com/pdf/news/enforcement-report-week-of-june-7-2023-80553.pdf

FDA
07 Jun 2023

https://www.pharmacompass.com/pdf/news/enforcement-report-week-of-november-21-2018-1542783991.pdf

FDA
21 Nov 2018

https://www.accessdata.fda.gov/scripts/ires/index.cfm?action=print.getPrintData&ts=812201872739

FDA
12 Sep 2018

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=204688

FDA
06 Dec 2017

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=203960

FDA
13 Jun 2017
Sobi gains commercial rights from Pharma Swiss
Sobi gains commercial rights from Pharma Swiss

07 Jan 2016

// Malin Anderson NORDIC LIFE SCIENCE

http://nordiclifescience.org/sobi-gains-commercial-rights-pharma-swiss/

Malin Anderson NORDIC LIFE SCIENCE
07 Jan 2016

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True Fix Pvt. Ltd., an innovative sourcing and distribution company is searching for suppliers of following products for registration and distribution in Brunei Darussalam: 61. Letrozole 2.5mg (Femara) Tablet 50 Units 62. Lomustine 40mg (CCNU) Capsule 50 Units 63. Megestrol Acetate 160mg (Megaplex 160) Tablet 50 Units 64. Mesna 400mg/4mL Injection 50 Units 65. Methotrexate 1000mg Injection 100 Units 66. Methotrexate 50mg/2mL Injection 100 Units 67. Mitomycin 10mg Injection 50 Units 68. Mitomycin 2mg Injection 50 Units 69. Mitotane 500mg (Lysodren) Tablet 50 Units 70. Mitoxantrone 20mg/10mL Injection 50 Units 71. Oxaliplatin 100mg Injection 100 Units 72. Paclitaxel 100mg (Abraxane) Injection 100 Units 73. Paclitaxel 150mg Injection 100 Units 74. Paclitaxel 300mg Injection 100 Units 75. Pazopanib 200mg (Votrient) Tablet 100 Units 76. Pazopanib 400mg (Votrient) Tablet 100 Units 77. Pegfilgrastim 6mg/0.6mL Injection 100 Units 78. Pemetrexed 500mg (Alimta) Injection 100 Units 79. Procarbazine 50mg Capsule 50 Units 80. Regorafenib 40mg (Stivarga) Tablet 50 Units 81. Rituximab 500mg/50mL Injection 100 Units 82. Sorafenib 200mg (Nexavar) Tablet 100 Units 83. Sunitinib 12.5mg (Sutent) Capsule (Hard) 50 Units 84. Tamoxifen 20mg 30's Tablet 100 Units 85. Temozolomide 100mg (Temodal) Capsule 50 Units 86. Trabectedin 1mg (Yondelis) Injection 50 Units 87. Trastuzumab 440mg Injection 100 Units 88. Vinblastine 10mg/10mL Injection 100 Units 89. Vincristine 2mg/2mL Injection 100 Units 90. Vinorelbine 50mg/5mL Injection 50 Units 91. Zoledronic Acid 800mcg/mL 5mL (Zometa) Injection 100 Units Interested suppliers should contact Rizuan Ajik via Email: rizuan@truefixpharma.com or Tel: +673 7246880.
09 Aug 2017

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REF. STANDARDS & IMPURITIES

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EDQM

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EDQM, Council of Europe

Nomegestrol acetate impurity A

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01

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Nomegestrol acetate impurity A

CAS Number : n/a

Quantity Per Vial : 50 mg

Sale Unit : 1

Order Code : N1080005

Batch No : 2

Price (€) : 79

Storage : +5°C ± 3°C

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EDQM, Council of Europe

Nomegestrol acetate

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Nomegestrol acetate

CAS Number : 58652-20-3

Quantity Per Vial : 100 mg

Sale Unit : 1

Order Code : N1080000

Batch No : 2

Price (€) : 79

Storage : +5°C ± 3°C

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EDQM, Council of Europe

Megestrol acetate for system suitability

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Megestrol acetate for system suitability

CAS Number : 595-33-5

Quantity Per Vial : 50 mg

Sale Unit : 1

Order Code : Y0001524

Batch No : 2

Price (€) : 79

Storage : +5°C ± 3°C

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Megestrol acetate for peak identificatio...

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Megestrol acetate for peak identification

CAS Number : 595-33-5

Quantity Per Vial : 25 mg

Sale Unit : 1

Order Code : Y0001507

Batch No : 1

Price (€) : 79

Storage : +5°C ± 3°C

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Megestrol acetate for impurity K identif...

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Megestrol acetate for impurity K identification

CAS Number : n/a

Quantity Per Vial : 0.01 mg

Sale Unit : 1

Order Code : Y0001594

Batch No : 1

Price (€) : 79

Storage : +5°C ± 3°C

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Megestrol acetate

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Megestrol acetate

CAS Number : 595-33-5

Quantity Per Vial : 120 mg

Sale Unit : 1

Order Code : Y0001514

Batch No : 1

Price (€) : 79

Storage : +5°C ± 3°C

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ANALYTICAL

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ABOUT THIS PAGE

Looking for 595-33-5 / Megestrol Acetate API manufacturers, exporters & distributors?

Megestrol Acetate manufacturers, exporters & distributors 1

67

PharmaCompass offers a list of Megestrol Acetate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Megestrol Acetate manufacturer or Megestrol Acetate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Megestrol Acetate manufacturer or Megestrol Acetate supplier.

PharmaCompass also assists you with knowing the Megestrol Acetate API Price utilized in the formulation of products. Megestrol Acetate API Price is not always fixed or binding as the Megestrol Acetate Price is obtained through a variety of data sources. The Megestrol Acetate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Megestrol Acetate

Synonyms

595-33-5, Megace, Megace es, Niagestin, Megestryl acetate, Megeron

Cas Number

595-33-5

Unique Ingredient Identifier (UNII)

TJ2M0FR8ES

About Megestrol Acetate

Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)

Megace, Megace ES, Megestrol Acetate Manufacturers

A Megace, Megace ES, Megestrol Acetate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Megace, Megace ES, Megestrol Acetate, including repackagers and relabelers. The FDA regulates Megace, Megace ES, Megestrol Acetate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Megace, Megace ES, Megestrol Acetate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Megace, Megace ES, Megestrol Acetate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Megace, Megace ES, Megestrol Acetate Suppliers

A Megace, Megace ES, Megestrol Acetate supplier is an individual or a company that provides Megace, Megace ES, Megestrol Acetate active pharmaceutical ingredient (API) or Megace, Megace ES, Megestrol Acetate finished formulations upon request. The Megace, Megace ES, Megestrol Acetate suppliers may include Megace, Megace ES, Megestrol Acetate API manufacturers, exporters, distributors and traders.

click here to find a list of Megace, Megace ES, Megestrol Acetate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Megace, Megace ES, Megestrol Acetate USDMF

A Megace, Megace ES, Megestrol Acetate DMF (Drug Master File) is a document detailing the whole manufacturing process of Megace, Megace ES, Megestrol Acetate active pharmaceutical ingredient (API) in detail. Different forms of Megace, Megace ES, Megestrol Acetate DMFs exist exist since differing nations have different regulations, such as Megace, Megace ES, Megestrol Acetate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Megace, Megace ES, Megestrol Acetate DMF submitted to regulatory agencies in the US is known as a USDMF. Megace, Megace ES, Megestrol Acetate USDMF includes data on Megace, Megace ES, Megestrol Acetate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Megace, Megace ES, Megestrol Acetate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Megace, Megace ES, Megestrol Acetate suppliers with USDMF on PharmaCompass.

Megace, Megace ES, Megestrol Acetate KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Megace, Megace ES, Megestrol Acetate Drug Master File in Korea (Megace, Megace ES, Megestrol Acetate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Megace, Megace ES, Megestrol Acetate. The MFDS reviews the Megace, Megace ES, Megestrol Acetate KDMF as part of the drug registration process and uses the information provided in the Megace, Megace ES, Megestrol Acetate KDMF to evaluate the safety and efficacy of the drug.

After submitting a Megace, Megace ES, Megestrol Acetate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Megace, Megace ES, Megestrol Acetate API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Megace, Megace ES, Megestrol Acetate suppliers with KDMF on PharmaCompass.

Megace, Megace ES, Megestrol Acetate CEP

A Megace, Megace ES, Megestrol Acetate CEP of the European Pharmacopoeia monograph is often referred to as a Megace, Megace ES, Megestrol Acetate Certificate of Suitability (COS). The purpose of a Megace, Megace ES, Megestrol Acetate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Megace, Megace ES, Megestrol Acetate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Megace, Megace ES, Megestrol Acetate to their clients by showing that a Megace, Megace ES, Megestrol Acetate CEP has been issued for it. The manufacturer submits a Megace, Megace ES, Megestrol Acetate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Megace, Megace ES, Megestrol Acetate CEP holder for the record. Additionally, the data presented in the Megace, Megace ES, Megestrol Acetate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Megace, Megace ES, Megestrol Acetate DMF.

A Megace, Megace ES, Megestrol Acetate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Megace, Megace ES, Megestrol Acetate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Megace, Megace ES, Megestrol Acetate suppliers with CEP (COS) on PharmaCompass.

Megace, Megace ES, Megestrol Acetate NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Megace, Megace ES, Megestrol Acetate as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Megace, Megace ES, Megestrol Acetate API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Megace, Megace ES, Megestrol Acetate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Megace, Megace ES, Megestrol Acetate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Megace, Megace ES, Megestrol Acetate NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Megace, Megace ES, Megestrol Acetate suppliers with NDC on PharmaCompass.

Megace, Megace ES, Megestrol Acetate GMP

Megace, Megace ES, Megestrol Acetate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Megace, Megace ES, Megestrol Acetate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Megace, Megace ES, Megestrol Acetate GMP manufacturer or Megace, Megace ES, Megestrol Acetate GMP API supplier for your needs.

Megace, Megace ES, Megestrol Acetate CoA

A Megace, Megace ES, Megestrol Acetate CoA (Certificate of Analysis) is a formal document that attests to Megace, Megace ES, Megestrol Acetate's compliance with Megace, Megace ES, Megestrol Acetate specifications and serves as a tool for batch-level quality control.

Megace, Megace ES, Megestrol Acetate CoA mostly includes findings from lab analyses of a specific batch. For each Megace, Megace ES, Megestrol Acetate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Megace, Megace ES, Megestrol Acetate may be tested according to a variety of international standards, such as European Pharmacopoeia (Megace, Megace ES, Megestrol Acetate EP), Megace, Megace ES, Megestrol Acetate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Megace, Megace ES, Megestrol Acetate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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