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1. Anhydrous Magnesium Carbonate
2. C.i. 77713
3. Carbonic Acid, Magnesium Salt (1:1), Hydrate
4. Ci 77713
5. E-504
6. Magnesite
7. Magnesite (mg(co3))
8. Magnesium Carbonate (1:1) Hydrate
9. Magnesium Carbonate Anhydrous
10. Mgco3.3h2o
11. Nesquehonite
1. 546-93-0
2. Magnesite
3. Carbonic Acid, Magnesium Salt
4. 13717-00-5
5. Carbonic Acid, Magnesium Salt (1:1)
6. Magnesium Carbonate Anhydrous
7. Magnesite Dust
8. Magnesite (mg(co3))
9. Magnesium;carbonate
10. Hydromagnesite
11. Magmaster
12. Magnesium Carbonate (1:1)
13. 7757-69-9
14. Carbonate Magnesium
15. C.i. 77713
16. Stan-mag Magnesium Carbonate
17. Magnesium Carbonate,light
18. Magnesium Carbonate (mgco3)
19. Dci Light Magnesium Carbonate
20. Ins No.504(i)
21. Anhydrous Magnesium Carbonate
22. Ins-504(i)
23. Magnesium Carbonate Gold Star
24. Magnesium(ii) Carbonate (1:1)
25. Chebi:31793
26. E-504(i)
27. Mfcd00064632
28. Nsc-83511
29. 0ihc698356
30. Giobertite
31. Kimboshi
32. Apolda
33. Destab
34. Magfy
35. Magnesium Carbonate, Hydrated
36. Caswell No. 530
37. Gp 20 (carbonate)
38. Ma 70 (carbonate)
39. Gold Star (carbonate)
40. Magnesium Carbonate [usan]
41. Australian Magnesite
42. Hsdb 211
43. Einecs 208-915-9
44. Nsc 83511
45. Epa Pesticide Chemical Code 073503
46. Ci 77713
47. Ai3-00768
48. Magnesiumkarbonat
49. Unii-0ihc698356
50. Einecs 231-817-2
51. Carbonic Acid, Magnesium Salt (1:?)
52. Mgco3
53. Magnesium Carbonate Usp
54. Ec 208-915-9
55. Magnesium Carbonate, Usp Grade
56. Chembl1200736
57. Dtxsid4049660
58. Magnesium Carbonate Microparticles
59. Cs-b1764
60. Magnesium Carbonate [who-dd]
61. Akos015903527
62. Db09481
63. E504
64. Anhydrous Magnesium Carbonate [mart.]
65. Ft-0774766
66. Q407931
67. Cyclopentanecarboxylic Acid, 3-methyl-2-oxo-, Methyl Ester
68. 53678-75-4
| Molecular Weight | 84.31 g/mol |
|---|---|
| Molecular Formula | CMgO3 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 83.9697855 g/mol |
| Monoisotopic Mass | 83.9697855 g/mol |
| Topological Polar Surface Area | 63.2 Ų |
| Heavy Atom Count | 5 |
| Formal Charge | 0 |
| Complexity | 18.8 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 2 |
THE CARBONATE ... /SALT/ OF MAGNESIUM /IS/ USED AS /ANTACID/, USUALLY IN COMBINATION WITH ALUMINUM HYDROXIDE.
American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 909
ALTHOUGH 1 G CONTAINS APPROX 20 MEQ ONLY FRACTION MAY BE AVAILABLE FOR NEUTRALIZATION IN VIVO. USUAL ANTACID DOSE OF 500 MG TO 2 G MAY BE INADEQUATE
Gilman, A. G., L. S. Goodman, and A. Gilman. (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 6th ed. New York: Macmillan Publishing Co., Inc. 1980., p. 993
MEDICATION (VET): WHEN INSOL IN DIGESTIVE TRACT IT IS ANTIDIARRHEAL & COATS MUCOSAE; WHEN SLIGHTLY SOL FORM IS USED IT CAN BE AS LAXATIVE AS MAGNESIUM OXIDE. ... COMMERCIALLY AVAILABLE COSMETIC GRADES EXIST FOR RARE USE AS TOPICAL PROTECTANT, MOISTURE & FAT ABSORBENT.
Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 319
AS AN ANTACID, IT IS RELATIVELY WEAK (1 G NEUTRALIZES APPROX 7 ML OF 0.1 N HCL IN 10 MIN & 17 ML IN 2 HR).
Osol, A. and J.E. Hoover, et al. (eds.). Remington's Pharmaceutical Sciences. 15th ed. Easton, Pennsylvania: Mack Publishing Co., 1975., p. 735
For more Therapeutic Uses (Complete) data for MAGNESIUM CARBONATE (8 total), please visit the HSDB record page.
3= MODERATELY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 0.5-5 G/KG; BETWEEN 1 OZ & 1 PINT (OR 1 LB) FOR 70 KG PERSON (150 LB).
Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-127
Used as an over the counter antacid.
FDA Label
Neutralizes acid in the stomach.
Bleaching Agents
Chemicals that are used to oxidize pigments and thus effect whitening. (See all compounds classified as Bleaching Agents.)
Hygroscopic Agents
Materials that readily absorb moisture from their surroundings. (See all compounds classified as Hygroscopic Agents.)
A - Alimentary tract and metabolism
A02 - Drugs for acid related disorders
A02A - Antacids
A02AA - Magnesium compounds
A02AA01 - Magnesium carbonate
A - Alimentary tract and metabolism
A06 - Drugs for constipation
A06A - Drugs for constipation
A06AD - Osmotically acting laxatives
A06AD01 - Magnesium carbonate
Absorption
About 40-60% of magnesium is absorbed following oral administration. Percent absorption decreases as dose increases.
Route of Elimination
Primarily eliminated in urine.
Volume of Distribution
Vd for magnesium is 0.2-0.4L/kg. About 50% distributes to bone.
Clearance
Maximum magnesium clearance is directly proportional to creatinine clearance.
IN SHEEP TRIAL REAGENT GRADE MATERIAL DEMONSTRATED 72% TRUE ABSORPTION VALUES, WHILE COMMERCIAL MAGNESITE HAD ONLY 14% VALUE DRAMATIZING NEED FOR MORE BIOLOGIC AVAILABILITY STUDIES ON MANY FEED INGREDIENTS.
Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 319
Magnesium does not appear to be metabolized in any way.
Half life of 27.7 hours reported with overdose of 400mEq of magnesium in an adult.
Magnesium carbonate reacts with hydrochloric acid in the stomach to form carbon dioxide and magnesium chloride thus neutralizing excess acid in the stomach.
... Rapidly reacts with hydrochloric acid to form ... carbon dioxide /and magnesium chloride/.
McEvoy, G.K. (ed.). American Hospital Formulary Service- Drug Information 2002. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2002 (Plus Supplements)., p. 2774
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