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Synopsis

Chemistry

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Also known as: 155206-00-1, Lumigan, Latisse, Agn 192024, Prostamide, Agn-192024
Molecular Formula
C25H37NO4
Molecular Weight
415.6  g/mol
InChI Key
AQOKCDNYWBIDND-FTOWTWDKSA-N
FDA UNII
QXS94885MZ

Bimatoprost
A cloprostenol-derived amide that is used as an ANTIHYPERTENSIVE AGENT in the treatment of OPEN-ANGLE GLAUCOMA and OCULAR HYPERTENSION.
Bimatoprost is a Prostaglandin Analog.
1 2D Structure

Bimatoprost

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
2.1.2 InChI
InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1
2.1.3 InChI Key
AQOKCDNYWBIDND-FTOWTWDKSA-N
2.1.4 Canonical SMILES
CCNC(=O)CCCC=CCC1C(CC(C1C=CC(CCC2=CC=CC=C2)O)O)O
2.1.5 Isomeric SMILES
CCNC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](CCC2=CC=CC=C2)O)O)O
2.2 Other Identifiers
2.2.1 UNII
QXS94885MZ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 192024, Agn

2. Agn 192024

3. Latisse

4. Lumigan

2.3.2 Depositor-Supplied Synonyms

1. 155206-00-1

2. Lumigan

3. Latisse

4. Agn 192024

5. Prostamide

6. Agn-192024

7. (z)-7-[(1r,2r,3r,5s)-3,5-dihydroxy-2-[(e,3s)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-n-ethylhept-5-enamide

8. Qxs94885mz

9. (z)-7-((1r,2r,3r,5s)-3,5-dihydroxy-2-((1e,3s)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-n-ethyl-5-heptenamide

10. Chebi:51230

11. (e)-7-[3,5-dihydroxy-2-[(e)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-n-ethylhept-5-enamide

12. Bimatoprostum

13. Unii-qxs94885mz

14. (5z)-7-{(1r,2r,3r,5s)-3,5-dihydroxy-2-[(1e,3s)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-n-ethylhept-5-enamide

15. (5z)-7-{(1r,2r,3r,5s)-3,5-dihydroxy-2-[(1e,3s)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl}-n-ethylhept-5-enamide

16. Lumigan (tn)

17. (z)-7-((1r,2r,3r,5s)-3,5-dihydroxy-2-((s,e)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)-n-ethylhept-5-enamide

18. (5z)-7-[(1r,2r,3r,5s)-3,5-dihydroxy-2-[(1e,3s)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-n-ethylhept-5-enamide

19. Bimatoprost [usan:inn:ban:jan]

20. Bimatoprost In Bulk

21. Latisse (tn)

22. Durysta

23. Ls-181817

24. Bimatoprost [mi]

25. Bimatoprost [inn]

26. Bimatoprost [jan]

27. (5z)-bimatoprost

28. Bimatoprost [inci]

29. Bimatoprost [usan]

30. Bimatoprost [vandf]

31. Bimatoprost [mart.]

32. Schembl24425

33. Bimatoprost [who-dd]

34. 5-heptenamide, 7-(3,5-dihydroxy-2-(3-hydrdoxy-5-phenyl-1-pentenyl)cyclopentyl)-n-ethyl-, (1r-(1alpha(z),2beta(1e,3s*),3alpha,5alpha))-

35. Mls006010039

36. Us9271961, Bimatoprost

37. Bimatoprost (jan/usan/inn)

38. Bimatoprost [ema Epar]

39. Gtpl1958

40. Chembl1200963

41. Bimatoprost [orange Book]

42. Dtxsid30895042

43. Bdbm220120

44. Ex-a1769

45. Ganfort Component Bimatoprost

46. Hy-b0191

47. Zinc4474405

48. Mfcd03411999

49. Akos015995566

50. Am84507

51. Bimatoprost Component Of Ganfort

52. Db00905

53. Fd10460

54. Ncgc00181745-01

55. Ncgc00181745-03

56. 5-heptenamide, 7-((1r,2r,3r,5s)-3,5-dihydroxy-2-((1e,3s)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-n-ethyl-, (5z)-

57. 5-heptenamide, 7-(3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-n-ethyl-, (1r-1(alpha(z),2beta(1e,3s*)3alpha,5alpha))-

58. As-35082

59. Smr000058996

60. B6165

61. D02724

62. 206b001

63. Sr-01000942224

64. Q2393348

65. Sr-01000942224-1

66. 17-phenyl Trinor Prostaglandin F2alpha Ethyl Amide

67. 17-phenyl-tri-norprostaglandin F2alpha-ethyl Amide, >=95%, Solid

68. 15m

69. 5-heptenamide, 7-(3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-n-ethyl-, (1r-1(.alpha.(z),2.beta.(1e,3s*)3.alpha.,5.alpha.))-

70. 5-heptenamide, 7-[(1r,2r,3r,5s)-3,5-dihydroxy-2-[(1e,3s)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-n-ethyl-, (5z)-

2.4 Create Date
2005-12-16
3 Chemical and Physical Properties
Molecular Weight 415.6 g/mol
Molecular Formula C25H37NO4
XLogP32.8
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count12
Exact Mass415.27225866 g/mol
Monoisotopic Mass415.27225866 g/mol
Topological Polar Surface Area89.8 Ų
Heavy Atom Count30
Formal Charge0
Complexity541
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 6  
Drug NameBimatoprost
PubMed HealthBimatoprost (Into the eye)
Drug ClassesAntiglaucoma, Ophthalmologic Agent
Drug LabelLATISSE (bimatoprost ophthalmic solution) 0.03% is a synthetic prostaglandin analog. Its chemical name is (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N-ethyl-5-heptenamide, and its molecular weight is 41...
Active IngredientBimatoprost
Dosage FormSolution
Routeophthalmic
Strength0.01%; 0.03%; 0.03
Market StatusTentative Approval
CompanyApotex; Sandoz

2 of 6  
Drug NameLatisse
PubMed HealthBimatoprost (Into the eye)
Drug ClassesAntiglaucoma, Ophthalmologic Agent
Drug LabelLATISSE (bimatoprost ophthalmic solution) 0.03% is a synthetic prostaglandin analog. Its chemical name is (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N-ethyl-5-heptenamide, and its molecular weight is 41...
Active IngredientBimatoprost
Dosage FormSolution/drops
RouteTopical
Strength0.03%
Market StatusPrescription
CompanyAllergan

3 of 6  
Drug NameLumigan
Drug LabelLUMIGAN 0.01% and 0.03% (bimatoprost ophthalmic solution) is a synthetic prostamide analog with ocular hypotensive activity. Its chemical name is (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-N-ethylhept...
Active IngredientBimatoprost
Dosage FormSolution/drops
RouteOphthalmic
Strength0.01%
Market StatusPrescription
CompanyAllergan

4 of 6  
Drug NameBimatoprost
PubMed HealthBimatoprost (Into the eye)
Drug ClassesAntiglaucoma, Ophthalmologic Agent
Drug LabelLATISSE (bimatoprost ophthalmic solution) 0.03% is a synthetic prostaglandin analog. Its chemical name is (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N-ethyl-5-heptenamide, and its molecular weight is 41...
Active IngredientBimatoprost
Dosage FormSolution
Routeophthalmic
Strength0.01%; 0.03%; 0.03
Market StatusTentative Approval
CompanyApotex; Sandoz

5 of 6  
Drug NameLatisse
PubMed HealthBimatoprost (Into the eye)
Drug ClassesAntiglaucoma, Ophthalmologic Agent
Drug LabelLATISSE (bimatoprost ophthalmic solution) 0.03% is a synthetic prostaglandin analog. Its chemical name is (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N-ethyl-5-heptenamide, and its molecular weight is 41...
Active IngredientBimatoprost
Dosage FormSolution/drops
RouteTopical
Strength0.03%
Market StatusPrescription
CompanyAllergan

6 of 6  
Drug NameLumigan
Drug LabelLUMIGAN 0.01% and 0.03% (bimatoprost ophthalmic solution) is a synthetic prostamide analog with ocular hypotensive activity. Its chemical name is (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-N-ethylhept...
Active IngredientBimatoprost
Dosage FormSolution/drops
RouteOphthalmic
Strength0.01%
Market StatusPrescription
CompanyAllergan

4.2 Drug Indication

Bimatoprost is used for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. These patients must be intolerant to other intraocular pressure lowering medications or inadequately responsive to other treatments. Bimatoprost is also indicated to treat eyelash hypotrichosis.


Reduction of elevated intraocular pressure in chronic open-angle glaucoma and ocular hypertension (as monotherapy or as adjunctive therapy to beta-blockers).


Treatment of glaucoma, Treatment of non-scarring hair loss


Treatment of androgenic alopecia


5 Pharmacology and Biochemistry
5.1 Pharmacology

High intraocular pressure is a major risk factor for glaucoma-related visual field loss. A linear relationship exists between intraocular pressure and the risk of damaging the optic nerve, which can lead to considerable visual impairment. Therefore, conditions such as ocular hypertension and glaucoma can cause dangerous elevations of intraocular pressure. Bimatoprost rapidly decreases intraocular pressure and reduces the risk for visual field loss from ocular hypertension due to various causes. Other effects of this drug may include gradual changes in eyelid pigmentation, changes in iris pigmentation, changes in eyelash pigmentation, growth and thickness. Patients should be informed of these possible effects, especially if this drug is only administered to one eye, which may noticeably change in appearance with bimatoprost treatment.


5.2 MeSH Pharmacological Classification

Antihypertensive Agents

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)


5.3 FDA Pharmacological Classification
5.3.1 Active Moiety
BIMATOPROST
5.3.2 FDA UNII
QXS94885MZ
5.3.3 Pharmacological Classes
Prostaglandins [CS]; Prostaglandin Analog [EPC]
5.4 ATC Code

S01EE03


S - Sensory organs

S01 - Ophthalmologicals

S01E - Antiglaucoma preparations and miotics

S01EE - Prostaglandin analogues

S01EE03 - Bimatoprost


5.5 Absorption, Distribution and Excretion

Absorption

This drug is absorbed systemically when administered to the eye. A study was performed on 15 healthy volunteers and bimatoprost ophthalmic solution 0.03% was administered once daily for 14 days. The mean Cmax was approximately 0.08 ng/mL and AUC0-24hr was approximately 0.09 on days 7 and 14 of the study. By 10 minutes, peak blood concentration was achieved. Bimatoprost was not detectable at 1.5 hours after administration in most subjects. The maximum blood concentration in a study of 6 healthy volunteers was determined to be 12.2 ng/mL. Steady state was reached in the first week of dosing. One drug label mentions that onset of decreased intraocular pressure occurs approximately 4 hours after the first administration and the peak effect occurs in the range of 8-12 hours. Bimatoprost effects may last up to 24 hours.


Route of Elimination

One pharmacokinetic study of bimatoprost in 6 healthy volunteers determined that 67% of the administered dose was found to be excreted in the urine while 25% of the dose was recovered in the feces.


Volume of Distribution

The volume of distribution at steady state is 0.67 L/kg.. It penetrates the human cornea and sclera.


Clearance

The clearance was measured to be 1.5 L/hr/kg in healthy subjects receiving IV administration of bimatoprost dosed at 3.12 ug/kg.


5.6 Metabolism/Metabolites

Bimatoprost is hydrolyzed to its active form, bimatoprost acid, in the eye. Bimatoprost undergoes oxidation, N-deethylation, and glucuronidation after it is systemically absorbed, and this leads to the production of various metabolites. In vitro studies show that CYP3A4 is an enzyme that participates in the metabolism of bimatoprost. Despite this, many enzymes and pathways metabolize bimatoprost, therefore, no significant drug-drug interactions are likely to occur. Glucuronidated metabolites comprise most of the excreted drug product in the blood, urine, and feces in rats.


5.7 Biological Half-Life

The elimination half-life of bimatoprost is approximately 45 minutes.


5.8 Mechanism of Action

Bimatoprost imitates the effects of prostamides, specifically prostaglandin F2. Bimatoprost mildly stimulates aqueous humor outflow, relieving elevated intraocular pressure and decreasing the risk of optic nerve damage. It is thought that bimatoprost reduces intraocular pressure (IOP) in humans by causing an increase in outflow of the aqueous humor via the trabecular meshwork and uveoscleral pathways. It achieves the above effects by decreasing tonographic resistance to aqueous humor outflow. Bimatoprost does not affect aqueous humor production.


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Virtual BoothEUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

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Bimatoprost

Registration Number : 229MF10098

Registrant's Address : To(´) utca 1-5. , 1045 Budapest, Hungary

Initial Date of Registration : 2017-05-24

Latest Date of Registration : 2017-05-24

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Bimatoprost

Registration Number : 228MF10186

Registrant's Address : 6Floor, Chung Ting Building No. 77, Section 2, Tun Hua South Road, Taipei, Taiwan

Initial Date of Registration : 2016-09-20

Latest Date of Registration : 2017-07-24

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Bimatoprost (for manufacturing purposes only)

Registration Number : 224MF10081

Registrant's Address : 530 Chokeiji, Takaoka City, Toyama Prefecture

Initial Date of Registration : 2012-04-13

Latest Date of Registration : 2023-02-08

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Bimatoprost

Registration Number : 220MF10035

Registrant's Address : 110 Industrial Parkway North, Aurora, Ontario L4G 3H4 Canada

Initial Date of Registration : 2008-02-05

Latest Date of Registration : 2009-12-22

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Bimatoprost "For manufacturing purposes only"

Registration Number : 229MF10152

Registrant's Address : 207, Sujeong-ro, Jangan-myeon, Manse-gu, Hwaseong-si, Gyeonggi-do, 18581, Republic of...

Initial Date of Registration : 2017-08-04

Latest Date of Registration : 2017-08-04

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About the Company : Inke S.A., is focused since 1980 in the development and manufacture of the highest quality Active Pharmaceutical Ingredients (APIs) with complex synthesis processes for diverse the...

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Virtual BoothTransoPharm USA works in the Sourcing and Management of Active Pharmaceutical Ingredients.

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LGM Pharma

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About the Company : LGM Pharma is a global leader in sourcing APIs, including hard-to-find drug substances, for pharmaceutical and biotech industries. LGM also operates as a full-service drug product ...

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About the Company : Jai Radhe Sales, founded in 1999, is a global distributor specializing in high-quality pharmaceutical ingredients from India. It offers complete sourcing solutions, technical and r...

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About the Company : HRV Pharma is a global manufacturer, seller, and exporter of APIs, intermediates, pellets, food-grade chemicals, food additives, and food ingredients. The company provides sourcing...

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Virtual BoothCapital Farma, a leading European pharmaceutical company focusing on the development & distribution of niche APIs & Pharma Services.

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Bimatoprost

About the Company : Capital Farma provides integrated pharmaceutical solutions with a focus on high-quality Active Pharmaceutical Ingredients (APIs) sourced from leading European manufacturers. The co...

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Bimatoprost manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Bimatoprost API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Bimatoprost manufacturer or Bimatoprost supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Bimatoprost manufacturer or Bimatoprost supplier.

API | Excipient name

Bimatoprost

Synonyms

155206-00-1, Lumigan, Latisse, Agn 192024, Prostamide, Agn-192024

Cas Number

155206-00-1

Unique Ingredient Identifier (UNII)

QXS94885MZ

About Bimatoprost

A cloprostenol-derived amide that is used as an ANTIHYPERTENSIVE AGENT in the treatment of OPEN-ANGLE GLAUCOMA and OCULAR HYPERTENSION.

Lumigan (TN) Manufacturers

A Lumigan (TN) manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Lumigan (TN), including repackagers and relabelers. The FDA regulates Lumigan (TN) manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Lumigan (TN) API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Lumigan (TN) manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

Lumigan (TN) Suppliers

A Lumigan (TN) supplier is an individual or a company that provides Lumigan (TN) active pharmaceutical ingredient (API) or Lumigan (TN) finished formulations upon request. The Lumigan (TN) suppliers may include Lumigan (TN) API manufacturers, exporters, distributors and traders.

click here to find a list of Lumigan (TN) suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

Lumigan (TN) USDMF

A Lumigan (TN) DMF (Drug Master File) is a document detailing the whole manufacturing process of Lumigan (TN) active pharmaceutical ingredient (API) in detail. Different forms of Lumigan (TN) DMFs exist exist since differing nations have different regulations, such as Lumigan (TN) USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Lumigan (TN) DMF submitted to regulatory agencies in the US is known as a USDMF. Lumigan (TN) USDMF includes data on Lumigan (TN)'s chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Lumigan (TN) USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Lumigan (TN) suppliers with USDMF on PharmaCompass.

Lumigan (TN) JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Lumigan (TN) Drug Master File in Japan (Lumigan (TN) JDMF) empowers Lumigan (TN) API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Lumigan (TN) JDMF during the approval evaluation for pharmaceutical products. At the time of Lumigan (TN) JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Lumigan (TN) suppliers with JDMF on PharmaCompass.

Lumigan (TN) KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Lumigan (TN) Drug Master File in Korea (Lumigan (TN) KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Lumigan (TN). The MFDS reviews the Lumigan (TN) KDMF as part of the drug registration process and uses the information provided in the Lumigan (TN) KDMF to evaluate the safety and efficacy of the drug.

After submitting a Lumigan (TN) KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Lumigan (TN) API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Lumigan (TN) suppliers with KDMF on PharmaCompass.

Lumigan (TN) WC

A Lumigan (TN) written confirmation (Lumigan (TN) WC) is an official document issued by a regulatory agency to a Lumigan (TN) manufacturer, verifying that the manufacturing facility of a Lumigan (TN) active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Lumigan (TN) APIs or Lumigan (TN) finished pharmaceutical products to another nation, regulatory agencies frequently require a Lumigan (TN) WC (written confirmation) as part of the regulatory process.

click here to find a list of Lumigan (TN) suppliers with Written Confirmation (WC) on PharmaCompass.

Lumigan (TN) NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Lumigan (TN) as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Lumigan (TN) API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Lumigan (TN) as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Lumigan (TN) and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Lumigan (TN) NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Lumigan (TN) suppliers with NDC on PharmaCompass.

Lumigan (TN) GMP

Lumigan (TN) Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Lumigan (TN) GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Lumigan (TN) GMP manufacturer or Lumigan (TN) GMP API supplier for your needs.

Lumigan (TN) CoA

A Lumigan (TN) CoA (Certificate of Analysis) is a formal document that attests to Lumigan (TN)'s compliance with Lumigan (TN) specifications and serves as a tool for batch-level quality control.

Lumigan (TN) CoA mostly includes findings from lab analyses of a specific batch. For each Lumigan (TN) CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Lumigan (TN) may be tested according to a variety of international standards, such as European Pharmacopoeia (Lumigan (TN) EP), Lumigan (TN) JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Lumigan (TN) USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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