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    Lorcaserin
    Also known as: Lorcaserin hcl, 846589-98-8, Lorqess, Lorcaserin (hydrochloride), Apd-356, Belviq
    Molecular Formula
    C11H15Cl2N
    Molecular Weight
    232.15  g/mol
    InChI Key
    ITIHHRMYZPNGRC-QRPNPIFTSA-N
    FDA UNII
    0QJF08GDPE
    1 2D Structure

    Lorcaserin

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (5R)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine;hydrochloride
    2.1.2 InChI
    InChI=1S/C11H14ClN.ClH/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9;/h2-3,6,8,13H,4-5,7H2,1H3;1H/t8-;/m0./s1
    2.1.3 InChI Key
    ITIHHRMYZPNGRC-QRPNPIFTSA-N
    2.1.4 Canonical SMILES
    CC1CNCCC2=C1C=C(C=C2)Cl.Cl
    2.1.5 Isomeric SMILES
    C[C@H]1CNCCC2=C1C=C(C=C2)Cl.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    0QJF08GDPE
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. (1r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine

    2. 8-chloro-2,3,4,5-tetrahydro-1-methyl-1h-3-benzazepine

    3. Apd 356

    4. Apd-356

    5. Apd356

    6. Ar-10a

    7. Belviq

    8. Lorcaserin

    2.3.2 Depositor-Supplied Synonyms

    1. Lorcaserin Hcl

    2. 846589-98-8

    3. Lorqess

    4. Lorcaserin (hydrochloride)

    5. Apd-356

    6. Belviq

    7. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-benzo[d]azepine Hydrochloride

    8. Apd356

    9. Lorcaserin Hydrochloride [usan]

    10. Belviq Xr

    11. 0qjf08gdpe

    12. Chebi:65350

    13. (1r)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1h-3-benzazepine Hydrochloride

    14. 846589-98-8 (hcl)

    15. Belviq (tn)

    16. (r)-1h-3-benzazepine,8-chloro-2,3,4,5-tetrahydro-1-methyl-,hydrochloride

    17. Lorcaserin Hydrochloride (usan)

    18. (1r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine Hydrochloride

    19. Unii-0qjf08gdpe

    20. Apd 356

    21. Schembl173899

    22. Chembl2095211

    23. Dtxsid60233650

    24. Act10402

    25. Bcp22731

    26. Ex-a1697

    27. Lorcaserin Hydrochloride (>50% Ee)

    28. Lorcaserin Hydrochloride [mi]

    29. Mfcd09833667

    30. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine Hydrochloride

    31. Akos005145786

    32. Ac-8945

    33. Bcp9000859

    34. Cs-0752

    35. Ks-1439

    36. 1h-3-benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-, Hydrochloride (1:1), (1r)-

    37. Lorcaserin Hydrochloride [vandf]

    38. Lorcaserin Hydrochloride [who-dd]

    39. Lorcaserin Hydrochloride Anhydrous

    40. Hy-15368

    41. Sw219573-1

    42. Lorcaserin Hydrochloride [orange Book]

    43. D06613

    44. Lorcaserin Hcl; Apd 356; Apd-356; Apd356;

    45. Q27888442

    46. (1r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepinium Chloride

    47. (5r)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine;hydrochloride

    48. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine Hydrochloride Salt

    49. (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-benzo[d]azepine Hydrochloride Hemihydrate

    50. 1h-3-benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-, Hydrochloride, (1r)-

    51. 1h-3-benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-,hydrochloride, (1r)-

    2.4 Create Date
    2006-10-26
    3 Chemical and Physical Properties
    Molecular Weight 232.15 g/mol
    Molecular Formula C11H15Cl2N
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count0
    Exact Mass231.0581549 g/mol
    Monoisotopic Mass231.0581549 g/mol
    Topological Polar Surface Area12 Ų
    Heavy Atom Count14
    Formal Charge0
    Complexity172
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameBelviq
    PubMed HealthLorcaserin (By mouth)
    Drug ClassesAntiobesity Agent
    Drug LabelBELVIQ (lorcaserin hydrochloride) is a serotonin 2C receptor agonist for oral administration used for chronic weight management. Its chemical name is (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate. The empirical f...
    Active IngredientLorcaserin hydrochloride
    Dosage FormTablet
    RouteOral
    Strength10mg
    Market StatusPrescription
    CompanyEisai

    2 of 2  
    Drug NameBelviq
    PubMed HealthLorcaserin (By mouth)
    Drug ClassesAntiobesity Agent
    Drug LabelBELVIQ (lorcaserin hydrochloride) is a serotonin 2C receptor agonist for oral administration used for chronic weight management. Its chemical name is (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate. The empirical f...
    Active IngredientLorcaserin hydrochloride
    Dosage FormTablet
    RouteOral
    Strength10mg
    Market StatusPrescription
    CompanyEisai

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