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1. 2-(diethylamino)-n-(2,6-dimethylphenyl)acetamide
2. 2-2etn-2mephacn
3. Dalcaine
4. Lidocaine Carbonate
5. Lidocaine Carbonate (2:1)
6. Lidocaine Hydrocarbonate
7. Lidocaine Hydrochloride
8. Lidocaine Monoacetate
9. Lidocaine Monohydrochloride
10. Lidocaine Monohydrochloride, Monohydrate
11. Lidocaine Sulfate (1:1)
12. Lignocaine
13. Octocaine
14. Xylesthesin
15. Xylocaine
16. Xylocitin
17. Xyloneural
1. 137-58-6
2. Lignocaine
3. Xylocaine
4. 2-(diethylamino)-n-(2,6-dimethylphenyl)acetamide
5. Lidoderm
6. Alphacaine
7. Anestacon
8. Esracaine
9. Xylestesin
10. Duncaine
11. Cappicaine
12. Gravocain
13. Isicaina
14. L-caine
15. Leostesin
16. Maricaine
17. Xylocain
18. Xylocitin
19. Solcain
20. Isicaine
21. Rucaina
22. Xilina
23. Xycaine
24. Xylotox
25. Cito Optadren
26. Lida-mantle
27. 2-(diethylamino)-2',6'-acetoxylidide
28. Dentipatch
29. Dalcaine
30. Xyloneural (free Base)
31. Cuivasil
32. Jetocaine
33. Lidocainum
34. Remicaine
35. Xilocaina
36. 2-diethylamino-n-(2,6-dimethylphenyl)acetamide
37. Acetamide, 2-(diethylamino)-n-(2,6-dimethylphenyl)-
38. Diethylaminoaceto-2,6-xylidide
39. Ela-max
40. Ztlido
41. 2',6'-acetoxylidide, 2-(diethylamino)-
42. Alpha-diethylamino-2,6-dimethylacetanilide
43. Lidocaton
44. Alfa-dietilamino-2,6-dimetilacetanilide
45. Chebi:6456
46. Xylocaine (tn)
47. Chembl79
48. Nsc-40030
49. Lidopen
50. N-(2,6-dimethylphenyl)-n~2~,n~2~-diethylglycinamide
51. Mls000069724
52. Algrx 3268
53. Algrx-3268
54. Lignocainum
55. Xllina
56. N-(2,6-dimethylphenyl)-n(2),n(2)-diethylglycinamide
57. Lidocaine (van)
58. .alpha.-diethylaminoaceto-2,6-xylidide
59. Ncgc00015611-10
60. Xilocaina [italian]
61. Dilocaine
62. Lidocaina
63. Smr000058189
64. .alpha.-(diethylamino)-2,6-acetoxylidide
65. Lidocaine Base
66. .alpha.-diethylamino-2,6-dimethylacetanilide
67. .omega.-diethylamino-2,6-dimethylacetanilide
68. 98pi200987
69. Lidocainum [inn-latin]
70. Dsstox_cid_25166
71. Dsstox_rid_80716
72. Dsstox_gsid_45166
73. Lidocaina [inn-spanish]
74. N-(2,6-dimethylphenyl)-n2,n2-diethylglycinamide
75. 2-(diethylamino)-n-(2,6-dimethylphenyl)ethanamide
76. Embolex
77. Versatis
78. Ztilido
79. 2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamide
80. Dentipatch (tn)
81. 91484-71-8
82. Cas-137-58-6
83. Lqz
84. Hsdb 3350
85. Einecs 205-302-8
86. Mfcd00026733
87. Nsc 40030
88. Alfa-dietilamino-2,6-dimetilacetanilide [italian]
89. Brn 2215784
90. Qualigens
91. Xyline
92. Lignocaine Base
93. Lidocainehclh2o
94. Lidocaine [usp:inn:ban:jan]
95. Lidocaine, Powder
96. Unii-98pi200987
97. N1-(2,6-dimethylphenyl)-n2,n2-diethylglycinamide
98. Zingo (salt/mix)
99. Cds1_000283
100. Lidocaine (alphacaine)
101. Spectrum_001118
102. Lidothesin (salt/mix)
103. Xyloneural (salt/mix)
104. Lidocaine [inn]
105. Lidocaine [jan]
106. Opera_id_385
107. Lidocaine [mi]
108. Lidocaine [hsdb]
109. Lidocaine [inci]
110. Maybridge1_002571
111. Prestwick0_000050
112. Prestwick1_000050
113. Prestwick2_000050
114. Prestwick3_000050
115. Spectrum2_001343
116. Spectrum3_001392
117. Spectrum4_000070
118. Spectrum5_001549
119. Lidocaine [vandf]
120. Lopac-l-5647
121. Lidaform Hc (salt/mix)
122. Epitope Id:116205
123. Lidocaine [mart.]
124. Lidamantle Hc (salt/mix)
125. 2', 2-(diethylamino)-
126. Lidocaine [usp-rs]
127. Lidocaine [who-dd]
128. Lidocaine [who-ip]
129. Neosporin Plus (salt/mix)
130. Lopac0_000669
131. Schembl15689
132. Bspbio_000179
133. Bspbio_001359
134. Bspbio_003004
135. Kbiogr_000079
136. Kbiogr_000599
137. Kbioss_000079
138. Kbioss_001598
139. 2-diethylamino-n-(2,6-dimethyl-phenyl)-acetamide
140. 4-12-00-02538 (beilstein Handbook Reference)
141. Mls000758263
142. Mls001074177
143. Mls001423964
144. Bidd:gt0342
145. Diethylaminoacet-2,6-xylidide
146. Divk1c_000174
147. Divk1c_001323
148. Lidocaine, Analytical Standard
149. Spbio_001525
150. Spbio_002100
151. Emla Component Lidocaine
152. Lidocaine (jp17/usp/inn)
153. Lidocaine [green Book]
154. Bpbio1_000197
155. Gtpl2623
156. Lidocaine [orange Book]
157. Dtxsid1045166
158. Lidocaine [ep Monograph]
159. Schembl17967359
160. Hms548m19
161. Kbio1_000174
162. Kbio2_000079
163. Kbio2_001598
164. Kbio2_002647
165. Kbio2_004166
166. Kbio2_005215
167. Kbio2_006734
168. Kbio3_000157
169. Kbio3_000158
170. Kbio3_002224
171. Oraqix Component Lidocaine
172. Synera Component Lidocaine
173. Zinc20237
174. Lidocaine [usp Monograph]
175. Lidocaine 1.0 Mg/ml In Methanol
176. Lidocainum [who-ip Latin]
177. Ninds_000174
178. Bio1_000379
179. Bio1_000868
180. Bio1_001357
181. Bio2_000079
182. Bio2_000559
183. Hms1791d21
184. Hms1989d21
185. Hms2051c21
186. Hms2089e15
187. Hms2235o14
188. Hms3371j04
189. Hms3393c21
190. Hms3428o07
191. Hms3651g09
192. Lidocaine Component Of Emla
193. Fortacin Component Lidocaine
194. Amy25560
195. Bcp09081
196. Hy-b0185
197. Nsc40030
198. Lidocaine Component Of Oraqix
199. Lidocaine Component Of Synera
200. Tox21_110183
201. 2-diethylamino-2',6'-acetoxylidide
202. Bdbm50017662
203. Lanabiotic Component Lidocaine
204. Nsc789222
205. S1357
206. Stk552033
207. Akos001026768
208. Lidocain Component Of Fortacine
209. Tox21_110183_1
210. Ccg-100824
211. Cs-2070
212. Db00281
213. Nc00074
214. Nsc-789222
215. Rocephin Kit Component Lidocaine
216. Sb19118
217. Sdccgsbi-0050648.p005
218. Wln: 2n2 & 1vmr B1 F1
219. .alpha.-diethylamino-2,6-acetoxylidide
220. Cas-73-78-9
221. Idi1_000174
222. Idi1_033829
223. Lidocaine Component Of Lanabiotic
224. Ncgc00015611-01
225. Ncgc00015611-02
226. Ncgc00015611-03
227. Ncgc00015611-04
228. Ncgc00015611-05
229. Ncgc00015611-06
230. Ncgc00015611-07
231. Ncgc00015611-08
232. Ncgc00015611-09
233. Ncgc00015611-11
234. Ncgc00015611-12
235. Ncgc00015611-13
236. Ncgc00015611-14
237. Ncgc00015611-15
238. Ncgc00015611-16
239. Ncgc00015611-18
240. Ncgc00015611-31
241. Ncgc00022176-05
242. Ncgc00022176-06
243. Ncgc00022176-07
244. Ncgc00022176-08
245. Ncgc00022176-09
246. Ac-10282
247. As-13718
248. Sy052029
249. 2-(diethylamino)-2'',6''-acetoxylidide
250. Lidocaine Component Of Rocephin Kit
251. Sbi-0050648.p004
252. Diethylamino-2,6-dimethylacetanilide
253. Lignocaine Base 100 Microg/ml In Methanol
254. Ab00053581
255. L0156
256. Sw196598-4
257. A18187
258. C07073
259. D00358
260. M06299
261. Ab00053581-27
262. Ab00053581-28
263. Ab00053581_29
264. Ab00053581_30
265. A833036
266. Q216935
267. (2,6-dimethylphenyl)carbamoylmethyl-diethyl-azanium
268. N1-(2,6-dimethylphenyl)-2-(diethylamino)acetamide
269. W-108233
270. 2-(diethylamino)-n-(2,6-dimethylphenyl)acetamide #
271. Brd-k52662033-001-02-6
272. Brd-k52662033-003-05-5
273. Brd-k52662033-003-14-7
274. Z55135799
275. Lidocaine, British Pharmacopoeia (bp) Reference Standard
276. Lidocaine, European Pharmacopoeia (ep) Reference Standard
277. N~1~-(2,6-dimethylphenyl)-n~2~,n~2~-diethylglycinamide
278. Lidocaine, United States Pharmacopeia (usp) Reference Standard
279. 2-(diethylamino)-n-(2,6-dimethylphenyl)acetamide Hydrate Hydrochloride
280. Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material
281. Lidocaine Solution, 1.0 Mg/ml In Methanol, Ampule Of 1 Ml, Certified Reference Material
1. Lignocaine
| Molecular Weight | 234.34 g/mol |
|---|---|
| Molecular Formula | C14H22N2O |
| XLogP3 | 2.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 5 |
| Exact Mass | 234.173213330 g/mol |
| Monoisotopic Mass | 234.173213330 g/mol |
| Topological Polar Surface Area | 32.3 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 228 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
| 1 of 12 | |
|---|---|
| Drug Name | Lidocaine |
| PubMed Health | Lidocaine |
| Drug Classes | Anesthetic, Local, Antiarrhythmic, Group IB |
| Drug Label | Lidocaine hydrochloride oral topical solution USP, 2% (viscous) contains a local anesthetic agent and is administered topically. Lidocaine hydrochloride oral topical solution USP, 2% (viscous) contains lidocaine HCl, which is chemically designated as... |
| Active Ingredient | Lidocaine |
| Dosage Form | Ointment; Patch |
| Route | Topical |
| Strength | 5% |
| Market Status | Prescription |
| Company | Taro; Fougera; Watson Labs; Novocol |
| Patent | 5741510; 5827529 |
| 2 of 12 | |
|---|---|
| Drug Name | Lidoderm |
| PubMed Health | Lidocaine |
| Drug Classes | Anesthetic, Local |
| Drug Label | DESCRIPTIONLIDODERM (lidocaine patch 5%) is comprised of an adhesive material containing 5% lidocaine, which is applied to a non-woven polyester felt backing and covered with a polyethylene terephthalate (PET) film release liner. The release liner is... |
| Active Ingredient | Lidocaine |
| Dosage Form | Patch |
| Route | Topical |
| Strength | 5% |
| Market Status | Prescription |
| Company | Teikoku Pharma Usa |
| Patent | 8540665; 5630796; 5899880; 6004286; 6881200 |
| 3 of 12 | |
|---|---|
| Drug Name | Octocaine |
| PubMed Health | Lidocaine |
| Drug Classes | Anesthetic, Local |
| Active Ingredient | lidocaine hydrochloride; Epinephrine |
| Dosage Form | Injectable |
| Route | Injection |
| Strength | 0.02mg/ml; 2%; 0.01mg/ml |
| Market Status | Prescription |
| Company | Septodont |
| 4 of 12 | |
|---|---|
| Drug Name | Xylocaine |
| PubMed Health | Lidocaine |
| Drug Label | XYLOCAINE - lidocaine hydrochloride injection, solutionXYLOCAINE - lidocaine hydrochloride and epinephrine bitartrate injection, solutionXYLOCAINE MPF - lidocaine hydrochloride injection, solutionXYLOCAINE - lidocaine hydrochloride and epinephrine bi... |
| Active Ingredient | Lidocaine hydrochloride |
| Dosage Form | Jelly; Injectable |
| Route | Injection; Topical |
| Strength | 0.5%; 1%; 1.5%; 2% |
| Market Status | Prescription |
| Company | Oak Pharms; Fresenius Kabi Usa |
| 5 of 12 | |
|---|---|
| Drug Name | Xylocaine viscous |
| PubMed Health | Lidocaine |
| Drug Label | Zingo (lidocaine hydrochloride monohydrate)powder intradermal injectionsystemcontains 0.5 mg of sterile lidocaine hydrochloride monohydrate.The chemical name is 2-diethylamino-2',6'-acetoxylidide, monohydrochloride, monohydrate. Themolecul... |
| Active Ingredient | Lidocaine hydrochloride |
| Dosage Form | Solution |
| Route | Oral |
| Strength | 2% |
| Market Status | Prescription |
| Company | Fresenius Kabi Usa |
| 6 of 12 | |
|---|---|
| Drug Name | Zingo |
| PubMed Health | Lidocaine |
| Active Ingredient | Lidocaine hydrochloride |
| Dosage Form | System |
| Route | Intradermal |
| Strength | 0.5mg |
| Market Status | Prescription |
| Company | Powder Pharms |
| 7 of 12 | |
|---|---|
| Drug Name | Lidocaine |
| PubMed Health | Lidocaine |
| Drug Classes | Anesthetic, Local, Antiarrhythmic, Group IB |
| Drug Label | Lidocaine hydrochloride oral topical solution USP, 2% (viscous) contains a local anesthetic agent and is administered topically. Lidocaine hydrochloride oral topical solution USP, 2% (viscous) contains lidocaine HCl, which is chemically designated as... |
| Active Ingredient | Lidocaine |
| Dosage Form | Ointment; Patch |
| Route | Topical |
| Strength | 5% |
| Market Status | Prescription |
| Company | Taro; Fougera; Watson Labs; Novocol |
| Patent | 5741510; 5827529 |
| 8 of 12 | |
|---|---|
| Drug Name | Lidoderm |
| PubMed Health | Lidocaine |
| Drug Classes | Anesthetic, Local |
| Drug Label | DESCRIPTIONLIDODERM (lidocaine patch 5%) is comprised of an adhesive material containing 5% lidocaine, which is applied to a non-woven polyester felt backing and covered with a polyethylene terephthalate (PET) film release liner. The release liner is... |
| Active Ingredient | Lidocaine |
| Dosage Form | Patch |
| Route | Topical |
| Strength | 5% |
| Market Status | Prescription |
| Company | Teikoku Pharma Usa |
| Patent | 8540665; 5630796; 5899880; 6004286; 6881200 |
| 9 of 12 | |
|---|---|
| Drug Name | Octocaine |
| PubMed Health | Lidocaine |
| Drug Classes | Anesthetic, Local |
| Active Ingredient | lidocaine hydrochloride; Epinephrine |
| Dosage Form | Injectable |
| Route | Injection |
| Strength | 0.02mg/ml; 2%; 0.01mg/ml |
| Market Status | Prescription |
| Company | Septodont |
| 10 of 12 | |
|---|---|
| Drug Name | Xylocaine |
| PubMed Health | Lidocaine |
| Drug Label | XYLOCAINE - lidocaine hydrochloride injection, solutionXYLOCAINE - lidocaine hydrochloride and epinephrine bitartrate injection, solutionXYLOCAINE MPF - lidocaine hydrochloride injection, solutionXYLOCAINE - lidocaine hydrochloride and epinephrine bi... |
| Active Ingredient | Lidocaine hydrochloride |
| Dosage Form | Jelly; Injectable |
| Route | Injection; Topical |
| Strength | 0.5%; 1%; 1.5%; 2% |
| Market Status | Prescription |
| Company | Oak Pharms; Fresenius Kabi Usa |
| 11 of 12 | |
|---|---|
| Drug Name | Xylocaine viscous |
| PubMed Health | Lidocaine |
| Drug Label | Zingo (lidocaine hydrochloride monohydrate)powder intradermal injectionsystemcontains 0.5 mg of sterile lidocaine hydrochloride monohydrate.The chemical name is 2-diethylamino-2',6'-acetoxylidide, monohydrochloride, monohydrate. Themolecul... |
| Active Ingredient | Lidocaine hydrochloride |
| Dosage Form | Solution |
| Route | Oral |
| Strength | 2% |
| Market Status | Prescription |
| Company | Fresenius Kabi Usa |
| 12 of 12 | |
|---|---|
| Drug Name | Zingo |
| PubMed Health | Lidocaine |
| Active Ingredient | Lidocaine hydrochloride |
| Dosage Form | System |
| Route | Intradermal |
| Strength | 0.5mg |
| Market Status | Prescription |
| Company | Powder Pharms |
Anesthetics, Local; Anti-Arrhythmia Agents; Voltage-Gated Sodium Channel Blockers
National Library of Medicine's Medical Subject Headings. Lidocaine. Online file (MeSH, 2014). Available from, as of August 28, 2014: https://www.nlm.nih.gov/mesh/2014/mesh_browser/MBrowser.html
Lidocaine hydrochloride is used for infiltration anesthesia and for nerve block techniques including peripheral, sympathetic, epidural (including caudal), and spinal block anesthesia. /Included in US product label/
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 3340
Lidocaine has been administered intraperitoneally for anesthesia of the peritoneum and pelvic viscera. /NOT included in US product label/
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 3340
Lidocaine is considered an alternative antiarrhythmic agent to amiodarone in the treatment of cardiac arrest secondary to ventricular fibrillation or pulseless ventricular tachycardia resistant to cardiopulmonary resuscitation (CPR), electrical cardioversion (e.g., after 2 to 3 shocks) and a vasopressor (epinephrine, vasopressin). /Included in US product label/
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1694
For more Therapeutic Uses (Complete) data for LIDOCAINE (21 total), please visit the HSDB record page.
WARNING: Life-threatening and fatal events in infants and young children. Postmarketing cases of seizures, cardiopulmonary arrest, and death in patients under the age of 3 years have been reported with use of Xylocaine 2% Viscous Solution when it was not administered in strict adherence to the dosing and administration recommendations. In the setting of teething pain, Xylocaine 2% Viscous Solution should generally not be used. For other conditions, the use of the product in patients less than 3 years of age should be limited to those situations where safer alternatives are not available or have been tried but failed. To decrease the risk of serious adverse events with use of Xylocaine 2% Viscous Solution, instruct caregivers to strictly adhere to the prescribed dose and frequency of administration and store the prescription bottle safely out of reach of children.
FDA; Prescribing Information for 2% Xylocaine Viscous (Lidocaine Hydrochloride) Solution (September 2014). Available from, as of November 2014: https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/009470s025lbl.pdf
Life-threatening adverse effects (e.g., irregular heart beat, seizures, breathing difficulties, coma, death) may occur when topical anesthetics are applied to a large area of skin, when the area of application is covered with an occlusive dressing, if a large amount of topical anesthetic is applied, if the anesthetic is applied to irritated or broken skin, or if the skin temperature increases (from exercise or use of a heating pad).101 102 When applied in such a manner, the amount of anesthetic that is absorbed systemically is unpredictable and the plasma concentrations achieved may be high enough to cause life-threatening adverse effects.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 3341-2
The Food and Drug Administration (FDA) has reviewed 35 reports of chondrolysis (necrosis and destruction of cartilage) in patients given continuous intra-articular infusions of local anesthetics with elastomeric infusion devices to control post-surgical pain. The significance of this injury to otherwise healthy young adults warrants notification to health care professionals. The local anesthetics (with and without epinephrine) were infused for extended periods of time (48 to 72 hours) directly into the intra-articular space using an elastomeric pump. Chondrolysis was diagnosed within a median of 8.5 months after the infusion. Almost all of the reported cases of chondrolysis (97%) occurred following shoulder surgeries. Joint pain, stiffness, and loss of motion were reported as early as the second month after receiving the infusion. In more than half of these reports, the patients required additional surgery, including arthroscopy or arthroplasty (joint replacement). It is not known which specific factor or combination of factors contributed to the development of chondrolysis in these cases. The infused local anesthetic drugs, the device materials, and/or other sources may have resulted in the development of chondrolysis. It is important to note that single intra-articular injections of local anesthetics in orthopedic procedures have been used for many years without any reported occurrence of chondrolysis. Local anesthetics are approved as injections for the production of local or regional anesthesia or analgesia. Neither local anesthetics nor infusion devices are approved for an indication of continuous intra-articular infusion.
FDA; Information for Healthcare Professionals: Chondrolysis Reported with Continuously Infused Local Anesthetics (Marketed as Bupivacaine, Chlorprocaine, Lidocaine, Mepivacaine, Procaine and Ropivacaine) (February 16, 2010). Available from, as of November 24, 2014: https://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm190302.htm
Local anesthetics should only be administered by clinicians who are experienced in the diagnosis and management of dose-related toxicities and other acute emergencies associated with these agents. Resuscitative equipment, oxygen, drugs, and personnel required for treatment of adverse reactions should be immediately available when lidocaine is administered. Proper positioning of the patient is extremely important in spinal anesthesia.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 3341
For more Drug Warnings (Complete) data for LIDOCAINE (31 total), please visit the HSDB record page.
Two fatal cases of deliberate self poisoning with lignocaine are reported, one by oral ingestion and one by iv injection. Post-mortem blood lignocaine concn were 40 and 53 mg/L, respectively.
PMID:2680899 Dawling S et al; Hum Toxicol 8 (5): 389-92 (1989)
Topical application of 25 g of lidocaine base twice daily led to death from cardiorespiratory arrest.
Ellenhorn, M.J., S. Schonwald, G. Ordog, J. Wasserberger. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams and Wilkins, 1997., p. 1199
Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.
FDA Label
Excessive blood levels of lidocaine can cause changes in cardiac output, total peripheral resistance, and mean arterial pressure. With central neural blockade these changes may be attributable to the block of autonomic fibers, a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system, and/or the beta-adrenergic receptor stimulating action of epinephrine when present. The net effect is normally a modest hypotension when the recommended dosages are not exceeded. In particular, such cardiac effects are likely associated with the principal effect that lidocaine elicits when it binds and blocks sodium channels, inhibiting the ionic fluxes required for the initiation and conduction of electrical action potential impulses necessary to facilitate muscle contraction. Subsequently, in cardiac myocytes, lidocaine can potentially block or otherwise slow the rise of cardiac action potentials and their associated cardiac myocyte contractions, resulting in possible effects like hypotension, bradycardia, myocardial depression, cardiac arrhythmias, and perhaps cardiac arrest or circulatory collapse. Moreover, lidocaine possesses a dissociation constant (pKa) of 7.7 and is considered a weak base. As a result, about 25% of lidocaine molecules will be un-ionized and available at the physiological pH of 7.4 to translocate inside nerve cells, which means lidocaine elicits an onset of action more rapidly than other local anesthetics that have higher pKa values. This rapid onset of action is demonstrated in about one minute following intravenous injection and fifteen minutes following intramuscular injection. The administered lidocaine subsequently spreads rapidly through the surrounding tissues and the anesthetic effect lasts approximately ten to twenty minutes when given intravenously and about sixty to ninety minutes after intramuscular injection. Nevertheless, it appears that the efficacy of lidocaine may be minimized in the presence of inflammation. This effect could be due to acidosis decreasing the amount of un-ionized lidocaine molecules, a more rapid reduction in lidocaine concentration as a result of increased blood flow, or potentially also because of increased production of inflammatory mediators like peroxynitrite that elicit direct actions on sodium channels.
Voltage-Gated Sodium Channel Blockers
A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS. (See all compounds classified as Voltage-Gated Sodium Channel Blockers.)
Anti-Arrhythmia Agents
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)
Anesthetics, Local
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)
N01BB02
S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355
N01BB02
S66 | EAWAGTPS | Parent-Transformation Product Pairs from Eawag | DOI:10.5281/zenodo.3754448
N01BB02
S66 | EAWAGTPS | Parent-Transformation Product Pairs from Eawag | DOI:10.5281/zenodo.3754448
N01BB02
S66 | EAWAGTPS | Parent-Transformation Product Pairs from Eawag | DOI:10.5281/zenodo.3754448
C - Cardiovascular system
C01 - Cardiac therapy
C01B - Antiarrhythmics, class i and iii
C01BB - Antiarrhythmics, class ib
C01BB01 - Lidocaine
C - Cardiovascular system
C05 - Vasoprotectives
C05A - Agents for treatment of hemorrhoids and anal fissures for topical use
C05AD - Local anesthetics
C05AD01 - Lidocaine
D - Dermatologicals
D04 - Antipruritics, incl. antihistamines, anesthetics, etc.
D04A - Antipruritics, incl. antihistamines, anesthetics, etc.
D04AB - Anesthetics for topical use
D04AB01 - Lidocaine
N - Nervous system
N01 - Anesthetics
N01B - Anesthetics, local
N01BB - Amides
N01BB02 - Lidocaine
R - Respiratory system
R02 - Throat preparations
R02A - Throat preparations
R02AD - Anesthetics, local
R02AD02 - Lidocaine
S - Sensory organs
S01 - Ophthalmologicals
S01H - Local anesthetics
S01HA - Local anesthetics
S01HA07 - Lidocaine
S - Sensory organs
S02 - Otologicals
S02D - Other otologicals
S02DA - Analgesics and anesthetics
S02DA01 - Lidocaine
Absorption
In general, lidocaine is readily absorbed across mucous membranes and damaged skin but poorly through intact skin. The agent is quickly absorbed from the upper airway, tracheobronchial tree, and alveoli into the bloodstream. And although lidocaine is also well absorbed across the gastrointestinal tract the oral bioavailability is only about 35% as a result of a high degree of first-pass metabolism. After injection into tissues, lidocaine is also rapidly absorbed and the absorption rate is affected by both vascularity and the presence of tissue and fat capable of binding lidocaine in the particular tissues. The concentration of lidocaine in the blood is subsequently affected by a variety of aspects, including its rate of absorption from the site of injection, the rate of tissue distribution, and the rate of metabolism and excretion. Subsequently, the systemic absorption of lidocaine is determined by the site of injection, the dosage given, and its pharmacological profile. The maximum blood concentration occurs following intercostal nerve blockade followed in order of decreasing concentration, the lumbar epidural space, brachial plexus site, and subcutaneous tissue. The total dose injected regardless of the site is the primary determinant of the absorption rate and blood levels achieved. There is a linear relationship between the amount of lidocaine injected and the resultant peak anesthetic blood levels. Nevertheless, it has been observed that lidocaine hydrochloride is completely absorbed following parenteral administration, its rate of absorption depending also on lipid solubility and the presence or absence of a vasoconstrictor agent. Except for intravascular administration, the highest blood levels are obtained following intercostal nerve block and the lowest after subcutaneous administration. Additionally, lidocaine crosses the blood-brain and placental barriers, presumably by passive diffusion.
Route of Elimination
The excretion of unchanged lidocaine and its metabolites occurs predominantly via the kidney with less than 5% in the unchanged form appearing in the urine. The renal clearance is inversely related to its protein binding affinity and the pH of the urine. This suggests by the latter that excretion of lidocaine occurs by non-ionic diffusion.
Volume of Distribution
The volume of distribution determined for lidocaine is 0.7 to 1.5 L/kg. In particular, lidocaine is distributed throughout the total body water. Its rate of disappearance from the blood can be described by a two or possibly even three-compartment model. There is a rapid disappearance (alpha phase) which is believed to be related to uptake by rapidly equilibrating tissues (tissues with high vascular perfusion, for example). The slower phase is related to distribution to slowly equilibrating tissues (beta phase) and to its metabolism and excretion (gamma phase). Lidocaine's distribution is ultimately throughout all body tissues. In general, the more highly perfused organs will show higher concentrations of the agent. The highest percentage of this drug will be found in skeletal muscle, mainly due to the mass of muscle rather than an affinity.
Clearance
The mean systemic clearance observed for intravenously administered lidocaine in a study of 15 adults was approximately 0.64 +/- 0.18 L/min.
Binding of lidocaine to plasma proteins is variable and concentration dependent. At concentrations of 1-4 ug/mL, the drug is approximately 60-80% bound to plasma proteins. Lidocaine is partially bound to a1-acid glycoprotein (a1-AGP), and the extent of binding to a1-AGP depends on the plasma concentration of the protein. In patients with myocardial infarction, increases in plasma a1-AGP concentration are associated with increased lidocaine binding and increased total plasma concentrations of the drug, but only small increases in plasma concentration of free drug; these changes in a1-AGP concentration and lidocaine binding are believed to account in part for accumulation of the drug observed in patients with myocardial infarction receiving prolonged infusions.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697
The volume of distribution is decreased in patients with congestive heart failure and increased in patients with liver disease.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697
Lidocaine is widely distributed into body tissues. After an IV bolus, there is an early, rapid decline in plasma concentrations of the drug, principally associated with distribution into highly perfused tissues such as the kidneys, lungs, liver, and heart, followed by a slower elimination phase in which metabolism and redistribution into skeletal muscle and adipose tissue occur. Lidocaine has a high affinity for fat and adipose tissue. As plasma concentrations of the drug fall, the diffusion gradient from tissue to blood increases and the lidocaine that initially entered the highly perfused tissues and fat diffuses back into the blood.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697
Plasma lidocaine concentrations of approximately 1-5 ug/mL are required to suppress ventricular arrhythmias. Toxicity has been associated with plasma lidocaine concentrations greater than 5 ug/mL. Following IV administration of a bolus dose of 50-100 mg of lidocaine hydrochloride, the drug has an onset of action within 45-90 seconds and a duration of action of 10-20 minutes. If an IV infusion is begun without an initial bolus dose, the attainment of therapeutic plasma concentrations is relatively slow. For example, therapeutic plasma concentrations are achieved in 30-60 minutes after the start of a continuous infusion of 60-70 ug/kg per minute when no loading dose is given. Plasma concentrations of 1.5-5.5 ug/mL have been reported to be maintained with an initial IV bolus of 1.5 mg/kg followed by infusion of 50 ug/kg per minute in patients with heart disease.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697
For more Absorption, Distribution and Excretion (Complete) data for LIDOCAINE (17 total), please visit the HSDB record page.
Lidocaine is metabolized predominantly and rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of lidocaine HCl. Approximately 90% of lidocaine HCl administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.
Approximately 90% of a parenteral dose of lidocaine is rapidly metabolized in the liver by de-ethylation to form MEGX and GX followed by cleavage of the amide bond to form xylidine and 4-hydroxyxylidine which are excreted in urine. Less than 10% of a dose is excreted unchanged in urine.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697
The rate of lidocaine metabolism may also be decreased in patients with liver disease, possibly because of altered perfusion in the liver or hepatic tissue necrosis. Distribution and elimination of lidocaine and /monoethylglycinexylidide/ MEGX appear to remain normal in patients with renal failure, but /glycinexylidide/ GX may accumulate in these patients when lidocaine is administered IV for several days.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697
... The purpose of this study is to determine the amount of lidocaine and its metabolite monoethyl-glycinexylidide (MEGX) in breast milk after local anesthesia during dental procedures. The study population consisted of seven nursing mothers (age, 23-39 years) who received 3.6 to 7.2 mL 2% lidocaine without adrenaline. Blood and milk concentrations of lidocaine and its metabolite MEGX were assayed using high-performance liquid chromatography. The milk-to-plasma ratio and the possible daily doses in infants for both lidocaine and MEGX were calculated. The lidocaine concentration in maternal plasma 2 hours after injection was 347.6 +/- 221.8 ug/L, the lidocaine concentration in maternal milk ranged from 120.5 +/- 54.1 ug/L (3 hours after injection) to 58.3 +/- 22.8 ug/L (6 hours after injection), the MEGX concentration in maternal plasma 2 hours after injection was 58.9 +/- 30.3 ug/L, and the MEGX concentration in maternal milk ranged from 97.5 +/- 39.6 ug/L (3 hours after injection) to 52.7 +/- 23.8 ug/L (6 hours after injection). According to these data and considering an intake of 90 mL breast milk every 3 hours, the daily infant dosages of lidocaine and MEGX were 73.41 +/- 38.94 ug/L/day and 66.1 +/- 28.5 ug/L/day respectively. This study suggests that even if a nursing mother undergoes dental treatment with local anesthesia using lidocaine without adrenaline, she can safely continue breastfeeding.
PMID:11321382 Giuliani M et al; J Pediatr Gastroenterol Nutr. 32(2):142-4. (2001).
... To determine the time/concentration profile of lidocaine and its active metabolites glycinexylidide (GX) and monoethylglycinexylidide (MEGX) during a 96 hr lidocaine infusion. lidocaine was administered to 8 mature healthy horses as a continuous rate infusion (0.05 mg/kg bwt/min) for 96 hr. Blood concentrations of lidocaine, GX and MEGX were determined using high performance liquid chromatography during and after discontinuation of the infusion. Serum lidocaine concentrations reached steady state by 3 hr and did not accumulate thereafter. Concentrations were above the target therapeutic concentration (980 ng/mL) only at 6 and 48 hr, and did not reach the range described as potentially causing toxicity (>1850 ng/mL) at any time. MEGX did not accumulate over time, while the GX accumulated significantly up to 48 hr and then remained constant. The serum concentrations of lidocaine, MEGX and GX were below the limit of detection within 24 hr of discontinuation of the infusion. None of the horses developed any signs of lidocaine toxicity during the study. The metabolism of lidocaine was not significantly impaired by prolonged infusion and no adverse effects were observed. Prolonged infusions appear to be safe in normal horses but the accumulation of GX, a potentially toxic active metabolite, is cause for concern.
PMID:18267881 Dickey EJ et al; Equine Vet J 40 (4): 348-52 (2008)
For more Metabolism/Metabolites (Complete) data for LIDOCAINE (11 total), please visit the HSDB record page.
Lidocaine has known human metabolites that include 3-Hydroxylidocaine and Monoethylglycinexylidide.
S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560
The elimination half-life of lidocaine hydrochloride following an intravenous bolus injection is typically 1.5 to 2.0 hours. Because of the rapid rate at which lidocaine hydrochloride is metabolized, any condition that affects liver function may alter lidocaine HCl kinetics. The half-life may be prolonged two-fold or more in patients with liver dysfunction.
... In 30 patients (aged 18-70 yr) undergoing surgery ... mean half-life ... lidocaine was ... 94 min.
Sanchez Alcaraz A et al; Farmacia Hosp 15 (Jul-Aug): 211-5 (1991)
... In patients with myocardial infarction (with or without cardiac failure), the half-lives of lidocaine and MEGX have been reported to be prolonged; the half-life of GX is reportedly prolonged in patients with cardiac failure secondary to myocardial infarction. The half-life of lidocaine is reportedly also prolonged in patients with congestive heart failure or liver disease and may be prolonged following continuous IV infusions lasting longer than 24 hours.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697
Lidocaine has an initial half-life of 7-30 minutes and a terminal half-life of 1.5-2 hours. In healthy individuals, the elimination half-lives of the active metabolites, monoethylglycinexylidide (MEGX) and glycinexylidide (GX) are 2 hours and 10 hours, respectively...
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697
Lidocaine is extensively metabolized by the liver; heaptic disease and reduced hepatic blood flow prolong the half life, which is normally < 1 hr in dogs.
National Fire Protection Association; Fire Protection Guide to Hazardous Materials. 14TH Edition, Quincy, MA 2010, p. 2162
The elimination half-life of lidocaine in the newborn following maternal epidual anesthesia averaged 3 hr.
Briggs, G.G., Freeman, R.K., Yaffee, S.J.; Drugs in Pregancy and Lactation Nineth Edition. Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia, PA. 2011, p. 832
Lidocaine is a local anesthetic of the amide type. It is used to provide local anesthesia by nerve blockade at various sites in the body. It does so by stabilizing the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action. In particular, the lidocaine agent acts on sodium ion channels located on the internal surface of nerve cell membranes. At these channels, neutral uncharged lidocaine molecules diffuse through neural sheaths into the axoplasm where they are subsequently ionized by joining with hydrogen ions. The resultant lidocaine cations are then capable of reversibly binding the sodium channels from the inside, keeping them locked in an open state that prevents nerve depolarization. As a result, with sufficient blockage, the membrane of the postsynaptic neuron will ultimately not depolarize and will thus fail to transmit an action potential. This facilitates an anesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their generation in the first place. In addition to blocking conduction in nerve axons in the peripheral nervous system, lidocaine has important effects on the central nervous system and cardiovascular system. After absorption, lidocaine may cause stimulation of the CNS followed by depression and in the cardiovascular system, it acts primarily on the myocardium where it may produce decreases in electrical excitability, conduction rate, and force of contraction.
Abnormal, repetitive impulse firing arising from incomplete inactivation of Na+ channels may be involved in several diseases of muscle and nerve, including familial myotonias and neuropathic pain syndromes. Systemic local anesthetics have been shown to have clinical efficacy against myotonias and some forms of neuropathic pain, so we sought to develop an in vitro model to examine the cellular basis for these drugs' effects. In frog sciatic nerves, studied in vitro by the sucrose-gap method, peptide alpha-toxins from sea anemone (ATXII) or scorpion (LQIIa) venom, which inhibit Na+ channel inactivation, induced repetitively firing compound action potentials (CAPs) superimposed on a plateau depolarization lasting several seconds. The initial spike of the CAP was unaffected, but the plateau and repetitive firing were strongly suppressed by 5-30 uM lidocaine. Lidocaine caused a rapid, concentration-dependent decay of the plateau, quantitatively consistent with blockade of open Na(+) channels. Early and late repetitive firing were equally suppressed by lidocaine with IC50 = 10 uM. After washout of lidocaine and LQIIa, the plateau and repetitive firing remained for > 1 hr, showing that lidocaine had not caused dissociation of channel-bound alpha-toxin. These findings indicate that therapeutic concentrations of lidocaine can reverse the "abnormal" features of action potentials caused by non-inactivating Na+ channels without affecting the normal spike component.
PMID:11317273 Khodorova A et al; Muscle Nerve 24 (5): 634-47 (2001)
Lidocaine controls ventricular arrhythmias by suppressing automaticity in the His-Purkinje system and by suppressing spontaneous depolarization of the ventricles during diastole. These effects occur at lidocaine concentrations that do not suppress automaticity of the sinoatrial (SA) node. At therapeutic plasma concentrations, lidocaine has little effect on atrioventricular (AV) node conduction and His-Purkinje conduction in the normal heart. Specialized conducting tissues of the atria are less sensitive to the effects of lidocaine than are those of ventricular tissues. Lidocaine has a variable effect on the effective refractory period (ERP) of the AV node; the drug shortens the ERP and the action potential duration of the His-Purkinje system. Lidocaine does not appear to affect excitability of normal cardiac tissue.
American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697
Prilocaine and lidocaine are classified as amide-type local anesthetics for which serious adverse effects include methemoglobinemia. Although the hydrolyzed metabolites of prilocaine (o-toluidine) and lidocaine (2,6-xylidine) have been suspected to induce methemoglobinemia, the metabolic enzymes that are involved remain uncharacterized. In the present study, we aimed to identify the human enzymes that are responsible for prilocaine- and lidocaine-induced methemoglobinemia. Our experiments revealed that prilocaine was hydrolyzed by recombinant human carboxylesterase (CES) 1A and CES2, whereas lidocaine was hydrolyzed by only human CES1A. When the parent compounds (prilocaine and lidocaine) were incubated with human liver microsomes (HLM), methemoglobin (Met-Hb) formation was lower than when the hydrolyzed metabolites were incubated with HLM. In addition, Met-Hb formation when prilocaine and o-toluidine were incubated with HLM was higher than that when lidocaine and 2,6-xylidine were incubated with HLM. Incubation with diisopropyl fluorophosphate and bis-(4-nitrophenyl) phosphate, which are general inhibitors of CES, significantly decreased Met-Hb formation when prilocaine and lidocaine were incubated with HLM. An anti-CYP3A4 antibody further decreased the residual formation of Met-Hb. Met-Hb formation after the incubation of o-toluidine and 2,6-xylidine with HLM was only markedly decreased by incubation with an anti-CYP2E1 antibody. o-Toluidine and 2,6-xylidine were further metabolized by CYP2E1 to 4- and 6-hydroxy-o-toluidine and 4-hydroxy-2,6-xylidine, respectively, and these metabolites were shown to more efficiently induce Met-Hb formation than the parent compounds. Collectively, we found that the metabolites produced by human CES-, CYP2E1-, and CYP3A4-mediated metabolism were involved in prilocaine- and lidocaine-induced methemoglobinemia.
PMID:23530020 Higuchi R et al; Drug Metab Dispos 41 (6): 1220-30 (2013)
Lidocaine acts primarily to inhibit sodium movement across cell membranes. In peripheral nerves, this action results in a decreased rate and degree of depolarization of nerve cells and failure to achieve the threshold potential necessary to propagate action potentials, resulting in conduction blockade and anesthesia. In the heart, lidocaine also inhibits sodium conductance, decreasing the maximal rate of depolarization of myocardial conducting cells. This effect is more prominent in cells that are ischemic and at rapid heart rates. For this reason lidocaine is most effective in the termination of rapid ventricular tachycardia, especially during acute ischemia or after myocardial infarction. Lidocaine may also increase the ventricular fibrillation threshold. At therapeutic doses, lidocaine has minimal electrophysiologic effects on normal cells.
Haddad, L.M., Clinical Management of Poisoning and Drug Overdose. 2nd ed. Philadelphia, PA: W.B. Saunders Co., 1990., p. 1372
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Grade : Parenteral, Oral, Topical
Application : Fillers, Diluents & Binders
Excipient Details : Captex 300 is used in parenteral solutions and suspensions, topical emulsions, and as filler and lubricant in capsules and tablets.
Pharmacopoeia Ref : EP, USP/NF, JP, US FDA
Technical Specs : LOW C6
Ingredient(s) : Glyceryl Tricaprylate Excipient
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Tablet
Grade : Oral, Topical
Application : Lubricants & Glidants
Excipient Details : Captex 355 is used in topical emulsions and as a lubricant and filler in capsules and tablets.
Pharmacopoeia Ref : EP, USP/NF, JP, US FDA
Technical Specs : N/A
Ingredient(s) : Glyceryl Tricaprylate Excipient
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Solution
Grade : Parenteral
Application : Parenteral
Excipient Details : Captex 355 INJ is used in parenteral solutions and suspensions.
Pharmacopoeia Ref : EP, USP/NF, JP, US FDA
Technical Specs : INJ Grade
Ingredient(s) : Glyceryl Tricaprylate Excipient
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Tablet
Grade : Parenteral, Oral, Topical
Application : Fillers, Diluents & Binders
Excipient Details : Captex 8000 is used in parenteral solutions and suspensions, topical emulsions, and as filler and lubricant in capsules and tablets.
Pharmacopoeia Ref : JP, US FDA
Technical Specs : N/A
Ingredient(s) : Glyceryl Tricaprylate Excipient
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Tablet
Grade : Parenteral, Oral, Topical
Application : Fillers, Diluents & Binders
Excipient Details : Captex INJ 8000 is used in topical emulsions, parenteral suspensions and solutions, and as a lubricant and filler in tablets and capsules.
Pharmacopoeia Ref : JP, US FDA
Technical Specs : N/A
Ingredient(s) : Glyceryl Tricaprylate Excipient
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Injectable / Parenteral
Grade : Parenteral, Oral
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Tablet
Grade : Oral
Application : Emulsifying Agents
Excipient Details : HDK N20 Pharma is used as a pharmaceutical emulsifying agent in tablets, capsules, syrups, and solutions.
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Tablet
Grade : Oral
Application : Taste Masking
Excipient Details : Insoluble saccharin (Q-0350, 15-191201) is used as an artificial sweetener in syrups, liquids, suspensions, mouthwashes, and tablets.
Pharmacopoeia Ref : USP/NF, JP, Kosher, ISO, Halal...
Technical Specs : Min. 98% Purity
Ingredient(s) : Saccharinum
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Ophthalmic Solution
Grade : Topical, Parenteral
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Jai Radhe Sales
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Nippon Fine Chemical
Nippon provides high-performance, high-value-added cosmetic, pharmaceutical, and industrial raw materials.
Dosage Form : Cream / Lotion / Ointment
Grade : Topical, Parenteral
Nippon provides high-performance, high-value-added cosmetic, pharmaceutical, and industrial raw materials.
Dosage Form : Gel
Grade : Topical, Inhalation
Application : Surfactant & Foaming Agents
Nippon provides high-performance, high-value-added cosmetic, pharmaceutical, and industrial raw materials.
Dosage Form : Injectable / Parenteral
Grade : Topical, Parenteral
Application : Co-Processed Excipients
Excipient Details : Presome ACD-1 is a mixture of HSPC/Cholesterol/MPEG2000-DSPE(3:1:1) that can greatly reduce the complexity of liposome production. It is used in parenteral dosage forms.
Pharmacopoeia Ref : NA
Technical Specs : Phospholipid/Cholesterol/MPEG2000-DSPE(3:1:1) Mixture
Ingredient(s) : Cholesterol Excipient
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]PMC Isochem
PMC Isochem is your partner for smart CDMOs of Intermediates, APIs, & excipients & a catalog of Intermediates & Generic APIs.
Dosage Form : Capsule
Grade : Oral, Parenteral, Nasal, Ophthalmic, Topical
Brand Name : ISODEL® Vitamin E TPGS (...
Application : Emulsifying Agents
Excipient Details : Vitamin E TPGS (Tocophersolan) is used as a solubilizer, emulsifying agent, plasticizer, stabilizer, and vehicle for lipid-based formulations.
Pharmacopoeia Ref : USP 40 – NF 35
Technical Specs : Specific Gravity: 1.06 at 50°C to 1.03 at 90°C; Solubility In Water: -20% at 20°C; Viscosity: 390...
Ingredient(s) : Tocophersolan
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Pharm-RX Chemical
Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.
Dosage Form : Cream / Lotion / Ointment
Grade : Oral, Topical
Pharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.
Dosage Form : Tablet
Grade : Oral, Topical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Boai NKY Pharmaceuticals Ltd
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Gangwal Healthcare
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Kewpie Corporation
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Nanjing Well Pharmaceutical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Pfanstiehl
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]ACG Worldwide
Dosage Form : Clinical Supply
Grade : Oral
Application : Empty Capsules
Excipient Details : ACGCAPS™ GC is specially designed for use in clinical trials and comes in the available sizes: AA, A & B.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Gelatin, Unspecified
Dosage Form : Inhalation
Grade : Inhalation
Application : Empty Capsules
Excipient Details : ACGCAPS™ GI / HI is available in gelatin and cellulose (HPMC) material options and is designed for optimal performance with DPI formulations and various inhalation devices.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Gelatin, Unspecified
Dosage Form : HardGel
Grade : Oral
Application : Empty Capsules
Excipient Details : ACGCAPS™ GL / HL is available in gelatin and cellulose (HPMC) material options and can be used for liquids, semi-liquids, hot-melts and combination fills.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Gelatin, Unspecified
Dosage Form : HardGel
Grade : Oral
Application : Empty Capsules
Excipient Details : ACGCAPS™ GR can fulfill immediate release needs and is available in 15 sizes (from # 000 to # 5).
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Gelatin, Unspecified
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Actylis
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Brand Name : 2-Phenoxyethanol PhEur
Application : Topical
Excipient Details : A & C's 2-Phenoxyethanol is used as an excipient and meets the EP monograph
Pharmacopoeia Ref : PhEur
Technical Specs : Not Available
Ingredient(s) : 2-Phenoxyethanol Excipient
Dosage Form : Ophthalmic Solution
Grade : Ophthalmic and Nasal
Brand Name : Benzalkonium Chloride
Application : Parenteral
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Benzalkonium chloride excipient
Dosage Form : Injectable / Parenteral
Grade : Parenteral and Topical
Application : Parenteral
Dosage Form : Injectable / Parenteral
Grade : Parenteral
Application : Parenteral
Excipient Details : A & C's Glycerol is an excipient which meets the USP monograph.
Dosage Form : Injectable / Parenteral
Grade : Parenteral
Brand Name : Hydrochloric Acid NF
Application : Parenteral
Excipient Details : A&C's Hydrochloric Acid NF is used as a low pH neutralizing agent for pharmaceutical applications.
Dosage Form : Tablet
Grade : Topical and Oral
Brand Name : Polyethylene Glycol 400
Application : Controlled & Modified Release
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : polyethylene glycol
Dosage Form : Capsule
Grade : Oral
Brand Name : Polysorbate 80 NF
Application : Solubilizers
Excipient Details : A & C's Polysorbate 80 is an excipient which meets the NF monograph.
Dosage Form : Cream / Lotion / Ointment
Grade : Topical and Oral
Application : Topical
Dosage Form : Injectable / Parenteral
Grade : Parenteral
Brand Name : Sodium Chloride USP
Application : Parenteral
Excipient Details : A & C's Sodium Chloride is an excipient meeting the USP monograph.
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Application : Topical
Excipient Details : A & C's Squalane is an excipient which meets NF monograph.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Aeon Procare
Dosage Form : Suspension
Grade : Oral and Topical
Application : Rheology Modifiers
Excipient Details : Bentonite is used in topical & oral preparations, formulation of suspensions and gels, aqueous preparation, cream bases and antidote in heavy metal poisoning.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Bentonite Excipient
Dosage Form : Cream / Lotion / Ointment
Grade : Topical & Oral
Application : Topical
Excipient Details : Kaolin is a naturally occurring mineral used in oral and topical pharmaceutical formulations
Dosage Form : Tablet
Grade : Oral & Topical
Application : Controlled & Modified Release
Excipient Details : Talc is a widely used as a dissolution retardant in the development of controlled release products. Talc is also used as a lubricant in tablet formulations.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Alcedo Pharmachem
Dosage Form : Tablet
Grade : Oral
Application : Fillers, Diluents & Binders
Excipient Details : Copovidone is used as a tablet binder, a film-former & as part of the matrix material used in controlled-release formulations.
Dosage Form : Tablet
Grade : Oral
Application : Direct Compression
Excipient Details : Crospovidone is an insoluble polymer of N-vinyl-2-pyrrolidone that is used as a disintegrant in pharmaceutical tablets.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]BASF
Dosage Form : Tablet
Grade : Not Available
Application : Controlled & Modified Release
Excipient Details : Solubilization, dispersion, crystallization inhibition, instant release matrices & spray drying
Dosage Form : Tablet
Grade : Not Available
Application : Solubilizers
Excipient Details : Solubilization, dispersion, crystallization inhibition, instant release matrices & spray drying
Pharmacopoeia Ref : Ph. Eur., USP, JP: Povidone
Technical Specs : Not Available
Ingredient(s) : Povidone
Dosage Form : Granule / Pellet
Grade : Not Available
Application : Disintegrants & Superdisintegrants
Excipient Details : Maximum disintegration
Pharmacopoeia Ref : Ph. Eur., USP, JP: Crospovidon...
Technical Specs : Not Available
Ingredient(s) : Polyvinylpyrrolidone Crosslinked
Dosage Form : Tablet
Grade : Not Available
Application : Granulation
Excipient Details : For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.
Pharmacopoeia Ref : Ph. Eur., USP-NF, JP-JPE: 80 %...
Technical Specs : Not Available
Ingredient(s) : Povidone
Dosage Form : Tablet
Grade : Not Available
Application : Film Formers & Plasticizers
Excipient Details : Liquid plasticizer with high ADI, hydrophilic solvent & humectant in emulsions, skin penetration enhancer in topical formulaitons.
Pharmacopoeia Ref : Ph. Eur., JP, FCC, USP
Technical Specs : Not Available
Ingredient(s) : Propylene Glycol
Dosage Form : Cream / Lotion / Ointment
Grade : Not Available
Application : Topical
Excipient Details : Structure-building consistency factor for semi-solids. Viscosity regulator.
Pharmacopoeia Ref : Ph. Eur., USP-NF: Cetyl alcoho...
Technical Specs : Not Available
Ingredient(s) : Cetyl Alcohol
Dosage Form : Softgel Capsule
Grade : Not Available
Application : Thickeners and Stabilizers
Excipient Details : Structure-building consistency factor with dry feel, forms crystalline barrier on skin
Pharmacopoeia Ref : Ph. Eur., USP-NF, JP: Stearic ...
Technical Specs : Not Available
Ingredient(s) : Stearic Acid
Dosage Form : Tablet
Grade : Not Available
Application : Granulation
Excipient Details : Lipophilic lubricant, for sensitive acidic APIs, Structure-building consistency factor for semi-solids, Viscosity regulator.
Pharmacopoeia Ref : Ph. Eur., USP-NF, JP: Stearyl ...
Technical Specs : Not Available
Ingredient(s) : Stearyl Alcohol
Dosage Form : Orodispersible Tablet
Grade : Not Available
Application : Chewable & Orodispersible Aids
Excipient Details : Ludiflash is a ready-to-use orally disintegrating tablet (ODT) solution with superior mouthfeel.
Pharmacopoeia Ref : Ph. Eur., USP, JP: 90 % mannit...
Technical Specs : Not Available
Ingredient(s) : Crospovidone
Dosage Form : Tablet
Grade : Not Available
Application : Granulation
Excipient Details : Ready-to-use direct compression solution for tablets.
Pharmacopoeia Ref : Ph.Eur., USP/NF and JP
Technical Specs : Not Available
Ingredient(s) : Crospovidone
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Bioplus Life Sciences
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Application : Emulsifying Agents
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]BioSpectra
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Application : Solubilizers
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Clariant
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Application : Topical
Excipient Details : Polyglykol 1000 is a pasty PEG excipient grade product which is used as solvent and ointment base in the topical formulations.
Pharmacopoeia Ref : USP-NF: Polyethylene glycol 10...
Technical Specs : average molar mass 1000 g/mol
Ingredient(s) : Polyethylene Glycol 1000
Dosage Form : Emulsion
Grade : Topical
Application : Rheology Modifiers
Excipient Details : Polyglykol 300 is a liquid PEG excipient grade product which is used as solvent, humectant, coating agent and viscosity enhancer.
Pharmacopoeia Ref : USP-NF: Polyethylene glycol 30...
Technical Specs : average molar mass 300 g/mol
Ingredient(s) : Polyethylene Glycol 300
Dosage Form : Emulsion
Grade : Topical
Application : Rheology Modifiers
Excipient Details : Polyglykol 400 is a liquid PEG excipient grade product which is used as solvent, humectant, coating agent and viscosity enhancer.
Pharmacopoeia Ref : USP-NF: Polyethylene glycol 40...
Technical Specs : average molar mass 400 g/mol
Ingredient(s) : Polyethylene Glycol 400
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Corel Pharma Chem
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Application : Topical
Excipient Details : It primarily function as efficient thickeners and co-binders at low usage level. It also acts as rheology modifiers in cream, lotion, gel etc.
Pharmacopoeia Ref : USP/NF : Carbomer 940
Technical Specs : Not Available
Ingredient(s) : Carbomer 940 Excipient
Dosage Form : Cream / Lotion / Ointment
Grade : Oral and Topical
Application : Topical
Excipient Details : It acts as rheology modifiers in cream, lotion, gel, oral suspension, transdermal gel reservoirs etc.
Pharmacopoeia Ref : USP/NF : Carbomer Homopolymer ...
Technical Specs : Not Available
Ingredient(s) : Carbomer Homopolymer Type B
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Application : Topical
Excipient Details : It primarily function as efficient thickeners and co-binders at low usage level. It also acts as rheology modifiers in cream, lotion, gel etc.
Pharmacopoeia Ref : USP/NF : Carbomer Homopolymer ...
Technical Specs : Not Available
Ingredient(s) : Carbomer Homopolymer Type C
Dosage Form : Gel
Grade : Topical
Application : Topical
Excipient Details : It is used as thickening agents, stabilizers and emulsifiers in topical formulations.
Pharmacopoeia Ref : USP/NF : Carbomer Copolymer Ty...
Technical Specs : Not Available
Ingredient(s) : Carbomer Copolymer Type B
Dosage Form : Gel
Grade : Topical
Application : Topical
Excipient Details : It is used as thickening agents, stabilizers and emulsifying agents in topical formulations.
Pharmacopoeia Ref : USP/NF : Carbomer Copolymer Ty...
Technical Specs : Not Available
Ingredient(s) : Carbomer Copolymer Type A
Dosage Form : Emulsion
Grade : Oral and Parenteral
Application : Emulsifying Agents
Excipient Details : Solubilizer, dissolution improver, emulsifier, masking agent, moisturizer, aerosol formulations.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Polyoxyl 40 Hydrogenated Castor Oil
Dosage Form : Emulsion
Grade : Not Available
Application : Emulsifying Agents
Excipient Details : Solubilizer, Dissolution Improver, Emulsifier, Masking Agent, Moisturizer, Aerosol Formulations
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Polyoxyl 50 Hydrogenated Castor Oil
Dosage Form : Nasal Solution
Grade : Not Available
Application : Solubilizers
Excipient Details : Solubilizer, dissolution improver, emulsifier, masking agent, moisturizer, aerosol formulations.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Polyoxyl 60 Hydrogenated Castor Oil
Dosage Form : Tablet
Grade : Not Available
Application : Coating Systems & Additives
Excipient Details : Film Coating
Dosage Form : Tablet
Grade : Not Available
Application : Coating Systems & Additives
Excipient Details : Film Coating
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]DFE Pharma
Dosage Form : Orodispersible Tablet
Grade : Oral
Application : Disintegrants & Superdisintegrants
Pharmacopoeia Ref : Conforms to USP-NF, Ph.Eur., J...
Technical Specs : Not Available
Ingredient(s) : Croscarmellose Sodium
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Doshion Polyscience
Dosage Form : Tablet
Grade : Oral
Application : Taste Masking
Excipient Details : It is used in taste masking of bitter drugs (Ambroxol, Ibuprofen) in suspension, tablets, etc.
Dosage Form : Tablet
Grade : Oral
Application : Taste Masking
Excipient Details : It is used in taste masking of bitter drugs (Azithromycin) in suspension, chewable tablets and dry syrups.
Dosage Form : Tablet
Grade : Oral
Application : Taste Masking
Excipient Details : It is used in taste masking of bitter drugs (Cefpodoxime Proxetil, Cefuoxime Axetil) in dispersible tablet, dry syrup, suspension, etc.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Finar
Dosage Form : Ophthalmic Solution
Grade : Ophthalmic and Nasal
Brand Name : Benzalkonium Chloride
Application : Parenteral
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Benzalkonium chloride excipient
Dosage Form : Injectable / Parenteral
Grade : Parenteral and Topical
Application : Parenteral
Dosage Form : Tablet
Grade : Topical and Oral
Brand Name : Polyethylene Glycol 400
Application : Controlled & Modified Release
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : polyethylene glycol
Dosage Form : Cream / Lotion / Ointment
Grade : Topical and Oral
Application : Topical
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Application : Topical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Gangwal Chemicals
Dosage Form : Tablet
Grade : Oral
Application : Taste Masking
Excipient Details : F-Melt Type C is a pharmaceutical excipient used in oral dosage forms like orally disintegrating tablets, sachets, dispersible tablets, chewable tablets and sublingual tablets.
Pharmacopoeia Ref : Conforms to Japanese Pharmaceu...
Technical Specs : Not Available
Ingredient(s) : Crospovidone
Dosage Form : Orodispersible Tablet
Grade : Oral
Application : Disintegrants & Superdisintegrants
Excipient Details : F-Melt Type M is used in various dosage forms like orally disintegrating tablets (ODTs), sachets, dispersible tablets, chewable tablets and sublingual formulations.
Pharmacopoeia Ref : Conforms to Japanese Pharmaceu...
Technical Specs : Not Available
Ingredient(s) : Crospovidone
Dosage Form : Tablet
Grade : Oral
Application : Fillers, Diluents & Binders
Excipient Details : Fujicalin SG is a pharmaceutical excipient that acts as a diluent, filler and cushioning agent.
Pharmacopoeia Ref : USP-NF, EP, JPC, US DMF Type I...
Technical Specs : Not Available
Ingredient(s) : Dibasic Calcium Phosphate
Dosage Form : Tablet
Grade : Oral
Application : Thickeners and Stabilizers
Excipient Details : Adsorbent, Moisture Protection, Stabilization of API
Pharmacopoeia Ref : USP-NF, JP, EP
Technical Specs : Also Available as FUJISIL-F
Ingredient(s) : Silicon Dioxide
Dosage Form : Ophthalmic Solution
Grade : Oral, Ophthalmic, Microsphere Injectable,Topical
Application : Parenteral
Excipient Details : Gohsenol EG acts as a pharmaceutical binder, filler and film former in various dosage forms like opthalmic, microsphere, OD strip and gel patches.
Pharmacopoeia Ref : JPE, USP, EP, ChP (China)
Technical Specs : Highly purified PVA, Partially hydrolysis, having all viscocity grade from 3cps to 48 cps.
Ingredient(s) : Polyvinyl Alcohol
Dosage Form : Capsule
Grade : Oral
Application : Fillers, Diluents & Binders
Pharmacopoeia Ref : USP-NF, EP, BP, IP, JP, FCC
Technical Specs : PVP K-K-30/ K-17/ K19/ K25/ K90
Ingredient(s) : Povidone
Dosage Form : Capsule
Grade : Oral
Application : Solubilizers
Excipient Details : Super disintegrate, solublity enhancer, Suspension stabilizer, Complexing agent, Low peroxide content, Long term stability
Pharmacopoeia Ref : Not Available
Technical Specs : Crospovidone (Type-A/B)- USP-NF / Ph. Eur. / BP / IP
Ingredient(s) : Crospovidone
Dosage Form : Capsule
Grade : Oral
Application : Coating Systems & Additives
Excipient Details : Ready mix Film coating system for moisture sensitive APIs
Pharmacopoeia Ref : USP, EP, JP; Having US-DMF
Technical Specs : Moisture barrier film coating system
Ingredient(s) : Hydroxypropyl Methyl Cellulose
Dosage Form : Capsule
Grade : Oral
Application : Coating Systems & Additives
Excipient Details : Ready mix Non-Functional film coating system.
Pharmacopoeia Ref : USP, EP, JP; Having US-DMF
Technical Specs : Not Available
Ingredient(s) : Hydroxypropyl Methyl Cellulose
Dosage Form : Capsule
Grade : Oral
Application : Solubilizers
Excipient Details : Polysorbate 80 in dry powder form, a solubilizing agent acts as a surfactant and increases the solubility of various oral dosage forms.
Pharmacopoeia Ref : USP-NF, EP, JP & having US DMF
Technical Specs : Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added durin...
Ingredient(s) : Magnesium aluminium silicate Excipient
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Huzhou Sunflower Pharmaceutical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Ideal Cures Pvt Ltd
Dosage Form : Tablet
Grade : Oral
Application : Coating Systems & Additives
Dosage Form : Tablet
Grade : Oral
Application : Coating Systems & Additives
Excipient Details : PVA is an excellent moisture barrier which reduces degradation of moisture sensitive APIs enabling extension of shelf-life and cost reductions via use of lower cost packaging
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Ingredion Pharma Solutions
Dosage Form : Tablet
Grade : Oral
Application : Rheology Modifiers
Excipient Details : Croscarmellose Sodium, Cellulose is used as a superdisintegrant and rheology modifier in oral dosage forms such as tablets.
Dosage Form : Emulsion
Grade : Oral, Topical
Application : Thickeners and Stabilizers
Excipient Details : Modified Starch, Corn is a white powder and a unique emulsion stabilising starch derived from waxy maize.
Dosage Form : Tablet
Grade : Oral
Application : Fillers, Diluents & Binders
Excipient Details : Fully Pregel Starch Corn is used as a binder in wet granulation in the manufacturing of tablets.
Pharmacopoeia Ref : USP/NF, Ph. Eur., Ch. P.
Technical Specs : NA
Ingredient(s) : Corn Starch, Pregelatinized
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Kerry
Dosage Form : Tablet
Grade : Not Available
Application : Co-Processed Excipients
Excipient Details : Orally Disintegrating Tablets
Dosage Form : Tablet
Grade : Not Available
Application : Co-Processed Excipients
Excipient Details : Direct Compression
Dosage Form : Tablet
Grade : Not Available
Brand Name : LubriTose™ Mannitol
Application : Co-Processed Excipients
Excipient Details : Standard Direct Tabletting
Dosage Form : Tablet
Grade : Not Available
Application : Co-Processed Excipients
Excipient Details : Direct Compression
Pharmacopoeia Ref : NF/EP/JP
Technical Specs : Not Available
Ingredient(s) : Microcrystalline Cellulose
Dosage Form : Tablet
Grade : Not Available
Application : Co-Processed Excipients
Excipient Details : Standard Direct Tabletting Or Roller Compaction
Dosage Form : Tablet
Grade : Not Available
Application : Co-Processed Excipients
Excipient Details : Direct Compression
Pharmacopoeia Ref : NF/EP/JP
Technical Specs : Not Available
Ingredient(s) : Spray Dried Monohydrate Lactose
Dosage Form : Tablet
Grade : Not Available
Application : Coating Systems & Additives
Excipient Details : Immediate Release
Pharmacopoeia Ref : Customized per requirements
Technical Specs : Not Available
Ingredient(s) : Polyvinyl Alcohol
Dosage Form : Tablet
Grade : Not Available
Application : Controlled & Modified Release
Excipient Details : Immediate Release
Pharmacopoeia Ref : Customized per requirements
Technical Specs : Not Available
Ingredient(s) : Hydroxypropyl Methylcellulose
Dosage Form : Tablet
Grade : Not Available
Application : Coating Systems & Additives
Excipient Details : Immediate Release
Pharmacopoeia Ref : Customized per requirements
Technical Specs : Not Available
Ingredient(s) : Polyvinyl Alcohol
Dosage Form : Tablet
Grade : Not Available
Application : Coating Systems & Additives
Excipient Details : Immediate Release
Pharmacopoeia Ref : Customized per requirements
Technical Specs : Not Available
Ingredient(s) : Polyvinyl Alcohol
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Kima Chemical
Dosage Form : Tablet
Grade : Oral
Brand Name : Carboxymethyl Cellulose
Application : Fillers, Diluents & Binders
Excipient Details : Carboxy Methyl Cellulose is used as a binder, disintegrant, film-former, and rheology modifier in the production of tablets and capsules.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Lonza Capsugel
Dosage Form : Clinical Supply
Grade : Oral
Application : Empty Capsules
Excipient Details : DBcaps® capsules are developed with a tamper-evident design to specifically address the clinical trial challenges of testing without bias.
Pharmacopoeia Ref : Not Available
Technical Specs : Size # AAA- E
Ingredient(s) : Gelatin, Unspecified
Dosage Form : HardGel
Grade : Oral
Application : Empty Capsules
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Gelatin, Unspecified
Dosage Form : Inhalation
Grade : Inhalation
Application : Empty Capsules
Pharmacopoeia Ref : Certified Vegan, Non-GMO, Vege...
Technical Specs : Size # 00el - 4
Ingredient(s) : Gelatin, Unspecified
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Lubrizol Life Science Health
Dosage Form : Gel
Grade : Topical
Application : Topical
Pharmacopoeia Ref : United States Pharmacopeia/Nat...
Technical Specs : Viscosity, cP (0.5 wt% at pH 7.5) - 35,500 - 39,400
Ingredient(s) : Carbomer Homopolymer Type B
Dosage Form : Gel
Grade : Topical
Application : Topical
Excipient Details : Carbopol® 940 NF polymer is a highly efficient thickener used for formulating clear aqueous and hydroalcoholic gels. The polymer has short flow rheology similar to mayonnaise.
Pharmacopoeia Ref : United States Pharmacopeia/Nat...
Technical Specs : Viscosity, cP (0.5 wt% at pH 7.5)- 40,000 - 60,000
Ingredient(s) : Carbomer 940 Excipient
Dosage Form : Tablet
Grade : Oral & Topical
Application : Controlled & Modified Release
Pharmacopoeia Ref : United States Pharmacopeia/Nat...
Technical Specs : Viscosity, cP (0.5 wt% at pH 7.5)- 29,400 - 39,400
Ingredient(s) : Carbomer Homopolymer Type B
Dosage Form : Gel
Grade : Topical
Application : Topical
Pharmacopoeia Ref : United States Pharmacopeia/Nat...
Technical Specs : Viscosity, cP (0.5 wt% at pH 7.5)- 40,000 - 60,000
Ingredient(s) : Carbomer Homopolymer Type C
Dosage Form : Gel
Grade : Topical and Oral
Brand Name : Carbopol ETD 2020 NF
Application : Thickeners and Stabilizers
Pharmacopoeia Ref : United States Pharmacopeia/Nat...
Technical Specs : Viscosity, cP (1.0 wt% at pH 7.5) - 4,000 - 10,000
Ingredient(s) : CARBOMER INTERPOLYMER TYPE B
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Brand Name : Carbopol Ultrez 10 NF
Application : Topical
Pharmacopoeia Ref : United States Pharmacopeia/Nat...
Technical Specs : Viscosity, cP (0.5 wt% at pH 7.5) - 45000 - 65,000
Ingredient(s) : CARBOMER INTERPOLYMER TYPE A
Dosage Form : Gel
Grade : Topical
Brand Name : Pemulen TR-1 NF Polymer
Application : Topical
Pharmacopoeia Ref : United States Pharmacopeia/Nat...
Technical Specs : Viscosity, cP (1.0 wt% at pH 7.5) - 10,000 - 26,500
Ingredient(s) : Carbomer Copolymer Type B
Dosage Form : Gel
Grade : Topical
Brand Name : Pemulen TR-2 NF Polymer
Application : Topical
Pharmacopoeia Ref : United States Pharmacopeia/Nat...
Technical Specs : Viscosity, cP (1.0 wt% at pH 7.5) - 4,500 - 13,500
Ingredient(s) : Carbomer Copolymer Type A
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Microlex e.U
Dosage Form : Tablet
Grade : Oral
Application : Thickeners and Stabilizers
Excipient Details : It provides solubility and viscosity stability on strong high viscosity.
Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE
Technical Specs : Strong High Viscosity
Ingredient(s) : Carboxymethyl cellulose sodium
Dosage Form : Tablet
Grade : Oral
Application : Thickeners and Stabilizers
Excipient Details : It provides smooth solutions, based on uniform substitution with low viscosity.
Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE
Technical Specs : Low Viscosity
Ingredient(s) : Carboxymethyl cellulose sodium
Dosage Form : Tablet
Grade : Oral
Application : Thickeners and Stabilizers
Excipient Details : It provides solubility and viscosity stability on medium viscosity.
Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE
Technical Specs : Medium Viscosity
Ingredient(s) : Carboxymethyl cellulose sodium
Dosage Form : Tablet
Grade : Oral
Application : Lubricants & Glidants
Excipient Details : Most popular excipient for the production of tablets and capsules. Offering an efficient and low dosage in capsules.
Pharmacopoeia Ref : Monograph- Ph.Eur, USP/NF
Technical Specs : Specific Surface Area-6-10 m2/g; Particle Size-7-11 µm
Ingredient(s) : Magnesium Stearate
Dosage Form : Tablet
Grade : Oral
Application : Lubricants & Glidants
Excipient Details : Higher specific surface area and a smaller median particle size. This product is preferred for more critical and very fine herbal formulations.
Pharmacopoeia Ref : Monograph- Ph.Eur, USP/NF
Technical Specs : Specific Surface Area-8-12 m2/g; Particle Size-5-9 µm
Ingredient(s) : Magnesium Stearate
Dosage Form : Tablet
Grade : Oral
Application : Lubricants & Glidants
Pharmacopoeia Ref : Monograph- Ph.Eur, USP/NF
Technical Specs : Specific Surface Area-6-8 m2/g; Particle Size-7-11 µm
Ingredient(s) : Magnesium Stearate
Dosage Form : Tablet
Grade : Oral
Application : Lubricants & Glidants
Pharmacopoeia Ref : Monograph- Ph.Eur, USP/NF
Technical Specs : Not Available
Ingredient(s) : Magnesium Stearate
Dosage Form : Tablet
Grade : Oral
Application : Lubricants & Glidants
Excipient Details : Meets Kosher and Halal preparations in Jewish and Arab cultures. Qualified in high specification standards requested by European formulators.
Pharmacopoeia Ref : Monograph- Ph.Eur, USP/NF
Technical Specs : Not Available
Ingredient(s) : Magnesium Stearate
Dosage Form : Cream / Lotion / Ointment
Grade : Topical, Oral
Application : Surfactant & Foaming Agents
Excipient Details : Sorbitan esters and their ethoxylates are a range of mild nonionic surfactants with multifunctional benefits in a number of healthcare applications.
Pharmacopoeia Ref : Monograph- Ph.Eur, USP/NF, FDA...
Technical Specs : Not Available
Ingredient(s) : Sorbitan Palmitate Excipient
Dosage Form : Cream / Lotion / Ointment
Grade : Topical, Oral
Application : Surfactant & Foaming Agents
Pharmacopoeia Ref : Monograph- Ph.Eur, USP/NF, FDA...
Technical Specs : Not Available
Ingredient(s) : sorbitan oleate
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Nanjing Bold Chemical
Dosage Form : Tablet
Grade : Oral & Parenteral
Application : Solubilizers
Excipient Details : Poloxamer 188 provides better storage stability. It is used as solubilizers for liquid preparation & oral care products, matrix materials for ointment & gel.
Dosage Form : Granule / Pellet
Grade : Oral & Topical
Application : Solubilizers
Excipient Details : Poloxamer 407 provides better storage stability. It is used as solubilizers for liquid preparation & oral care products, matrix materials for ointment & gel.
Dosage Form : Tablet
Grade : Oral, Topical & Parenteral
Application : Solubilizers
Excipient Details : Polysorbate 80 acts as solubilizer, emulsifier and wetting agent.
Dosage Form : Tablet
Grade : Oral & Topical
Application : Solubilizers
Excipient Details : Sorbitan Monooleate (Span 80) is used as oily emulsifier, solubilizer, thickener.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Sorbitan Monooleate
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Nomisma Healthcare
Dosage Form : Tablet
Grade : Oral, Parenteral
Application : Controlled & Modified Release
Excipient Details : PLGA-PEG is used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.
Pharmacopoeia Ref : NA
Technical Specs : Nano-particles, ultrapure, low-monomer & powder grades.
Ingredient(s) : Poly-DL-Lactic-co-Glycolic Acid
Dosage Form : Tablet
Grade : Oral, Parenteral
Application : Controlled & Modified Release
Excipient Details : PLLA-PEG used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.
Pharmacopoeia Ref : NA
Technical Specs : Nano-particles, ultrapure, low-monomer & powder grades
Ingredient(s) : Poly L Lactide
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Novo Excipients
Dosage Form : Tablet
Grade : Oral
Application : Fillers, Diluents & Binders
Excipient Details : Copovidone is used as a film-former and binding agent in oral solids such as tablets and capsules.
Dosage Form : Tablet
Grade : Oral
Application : Granulation
Excipient Details : Crospovidone is used as a granulating agent in pharmaceutical formulations such as tablets, granules, and pellets.
Dosage Form : Tablet
Grade : Oral
Application : Coating Systems & Additives
Excipient Details : Novomix is used as a ready mix film coating system in the production of pharmaceutical tablets.
Dosage Form : Tablet
Grade : Oral
Brand Name : Polyvinylpyrrolidone
Application : Fillers, Diluents & Binders
Excipient Details : Polyvinylpyrrolidone is used as a low-viscosity wet-binding agent in the production of tablets, capsules, and granules.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Pharmatrans-Sanaq
Dosage Form : Tablet
Grade : Oral
Application : Fillers, Diluents & Binders
Excipient Details : Polyvinylpyrrolidone is used as a binder and disintegrating agent in the formulation of tablets, also it can affect the release of the drug into the body.
Dosage Form : Suspension
Grade : Oral
Application : Thickeners and Stabilizers
Excipient Details : Crospovidone is used as disintegrant in formulation of tablets and hard gelatin capsules and as stabilizer in development of oral suspensions.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Pluviaendo
Dosage Form : Tablet
Grade : Oral
Application : Fillers, Diluents & Binders
Excipient Details : Corn Starch is used as a filler and binder in pharmaceutical oral solid dosage forms including tablets and capsules.
Dosage Form : Tablet
Grade : Oral
Brand Name : Croscarmellose Sodium
Application : Disintegrants & Superdisintegrants
Excipient Details : Croscarmellose Sodium is used as a super disintegrant in various oral solid dosage forms such as tablets, capsules, and orodispersible tablets (ODTs).
Dosage Form : Softgels
Grade : Oral, Topical, Parenteral
Application : Film Formers & Plasticizers
Excipient Details : Glycerin is used as a plasticizer in softgel capsules & tablets. It is also used in topical creams & emulsions & as a solvent in parenteral products.
Dosage Form : Injectable / Parenteral
Grade : Parenteral
Application : Thickeners and Stabilizers
Excipient Details : L-arginine is used as a cryoprotective agent and solution additive in the stabilization of proteins against aggregation.
Dosage Form : Tablet
Grade : Oral
Brand Name : Magnesium Stearate
Application : Lubricants & Glidants
Excipient Details : Magnesium stearate is the magnesium salt of stearic acid. It acts as a lubricating agent in tablet manufacturing.
Dosage Form : Tablet
Grade : Oral
Brand Name : Polyvinylpyrrolidone
Application : Fillers, Diluents & Binders
Excipient Details : Polyvinylpyrrolidone is used as a low-viscosity wet-binding agent in the production of solid oral dosage forms such as tablets and capsules.
Dosage Form : Tablet
Grade : Oral
Brand Name : Sodium Dodecyl Sulfate
Application : Granulation
Excipient Details : Sodium Dodecyl Sulfate is used as an ionic surfactant, lubricant, and granulating agent in the solid dosage forms such as tablets.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Prachin Chemical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Qualicaps
Dosage Form : Clinical Supply
Grade : Oral
Application : Empty Capsules
Excipient Details : Quali-G™ is first preservative-free gelatin capsule, the market standard solid dosage form designed to meet the demanding requirements of the pharmaceutical industry.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Gelatin, Unspecified
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Roquette
Dosage Form : Softgel Capsule
Grade : Not Available
Application : Soft Gelatin
Dosage Form : Tablet
Grade : Not Available
Application : Fillers, Diluents & Binders
Excipient Details : It is a natural pregelatinized maize starch that has been specially developed as a binder for wet granulation.
Dosage Form : Tablet
Grade : Not Available
Application : Disintegrants & Superdisintegrants
Excipient Details : Used as disintegrants, fillers and binders (once cooked) in nutraceutical and pharmaceutical dosage forms.
Dosage Form : Syrup
Grade : Not Available
Application : Taste Masking
Excipient Details : Act as a bulk sweetener and vehicle in liquid dosage forms and as a humectant in semi solids.
Pharmacopoeia Ref : EP/USP, USP/FCC
Technical Specs : Not Available
Ingredient(s) : Sorbitol liquid crystallizing
Dosage Form : Syrup
Grade : Not Available
Brand Name : NEOSORB® 70/02 SB
Application : Taste Masking
Excipient Details : Act as a bulk sweetener and vehicle in liquid dosage forms and as a humectant in semi solids.
Pharmacopoeia Ref : EP/USP
Technical Specs : Not Available
Ingredient(s) : Sorbitol liquid crystallizing
Dosage Form : Tablet
Grade : Not Available
Application : Fillers, Diluents & Binders
Excipient Details : It act as a filler & fiiller/binder as well as a bulk sweetener. It is non-cariogenic, non-acidogenic and sugar-free.
Dosage Form : Injectable / Parenteral
Grade : Not Available
Application : Parenteral
Excipient Details : A pyrogen-free sorbitol used as a carbohydrate source and osmotic diuretic agent in large volume parenteral injectables.
Dosage Form : Tablet
Grade : Not Available
Application : Fillers, Diluents & Binders
Dosage Form : Tablet
Grade : Not Available
Application : Disintegrants & Superdisintegrants
Excipient Details : It is a superdisintegrant that provides an efficient disintegration at low level of use
Dosage Form : Tablet
Grade : Not Available
Application : Fillers, Diluents & Binders
Excipient Details : Used as disintegrants, fillers and binders (once cooked) in nutraceutical and pharmaceutical dosage forms.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Corn Starch, Colloidal Silica
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Seppic
Dosage Form : Foam
Grade : Topical
Application : Topical
Excipient Details : Foaming Agent, Amphoteric Surfactant
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Cocamidopropyl Betaine
Dosage Form : Capsule
Grade : Topical, Oral
Brand Name : MONTANE 80 PHA PREMIUM
Application : Emulsifying Agents
Excipient Details : Non-ionic lipophilic surfactant, emulsifier.
Pharmacopoeia Ref : Ph.Eur, USP-NF
Technical Specs : HLB: 4; EXCiPACT
Ingredient(s) : Sorbitan Oleate
Dosage Form : Injectable / Parenteral
Grade : Injectable
Application : Parenteral
Excipient Details : Non-Ionic Lipophilic Surfactant, Emulsifier
Dosage Form : Injectable / Parenteral
Grade : Injectable
Application : Solubilizers
Excipient Details : Non-Ionic Hydrophilic Surfactant, Emulsifier, Solubilizer
Dosage Form : Injectable / Parenteral
Grade : Injectable
Application : Solubilizers
Excipient Details : Non-Ionic Hydrophilic Surfactant, Emulsifier, Solubilizer
Dosage Form : Injectable / Parenteral
Grade : Injectable
Application : Solubilizers
Excipient Details : Non-Ionic Hydrophilic Surfactant, Emulsifier, Solubilizer
Dosage Form : Injectable / Parenteral
Grade : Injectable
Application : Solubilizers
Excipient Details : Non-Ionic Hydrophilic Surfactant, Emulsifier, Solubilizer
Dosage Form : Emulsion
Grade : Topical
Application : Topical
Excipient Details : O/W Emulsifier, Self-Emulsifier
Pharmacopoeia Ref : Not Available
Technical Specs : Self-Emulsifying Base
Ingredient(s) : Cetearyl alcohol with Cetearyl glucoside
Dosage Form : Granule / Pellet
Grade : Oral
Application : Direct Compression
Excipient Details : Capsule Filling, Direct Compression, Binding, Disintegration
Pharmacopoeia Ref : Not Available
Technical Specs : EXCiPACT
Ingredient(s) : Native & Pregelatinized Corn Starch
Dosage Form : Dry Syrup
Grade : Oral
Application : Co-Processed Excipients
Excipient Details : Solubilizer
Pharmacopoeia Ref : Not Available
Technical Specs : Solubilizer in powder form; EXCiPACT
Ingredient(s) : Polyoxyl 40 hydrogenated castor oil
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Shandong Focus Biotechnology Co., Ltd
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Shanghai Shenmei Pharmaceutical Technology Co., Ltd
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Shijiazhuang Huaxu Pharmaceutical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Sigachi Industries
Dosage Form : Emulsion
Grade : Oral
Application : Rheology Modifiers
Excipient Details : HiCel MCG is use in oral suspensions as a stabilizer & emulsion prepared with high shear forces. It is a good binder for tablets & excellent stabilizer as well as thickener.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Carboxymethyl cellulose sodium
Dosage Form : Tablet
Grade : Oral
Application : Fillers, Diluents & Binders
Excipient Details : HiCel SMCC has unique combination which result in optimum compaction & superior flow properties.
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Microcrystalline Cellulose
Dosage Form : Tablet
Grade : Oral
Application : Disintegrants & Superdisintegrants
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Croscarmellose Sodium
Dosage Form : Tablet
Grade : Oral
Application : Lubricants & Glidants
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]The Dow Chemical Company
Dosage Form : Tablet
Grade : Not Available
Application : Rheology Modifiers
Excipient Details : Tablet Coating, Rheology Modifier
Pharmacopoeia Ref : Not Available
Technical Specs : Not Available
Ingredient(s) : Carboxymethyl cellulose sodium
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Ulanqab Kema New Material
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Valens Pharmachem
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Application : Surfactant & Foaming Agents
Excipient Details : Hydrosol 40 is a nonionic surfactant used as an emulsifying agent & solubilizer in pharmaceutical formulations in topical semi-solid dosage forms.
Dosage Form : Solution
Grade : Oral, Topical
Application : Solubilizers
Excipient Details : Hydrosol 50 is used as a solubilizer and emulsifying agent in oral and topical liquid and semi-solid dosage forms.
Pharmacopoeia Ref : USP/NF
Technical Specs : N/A
Ingredient(s) : Polyoxyl 40 Hydrogenated Castor Oil
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Vasa Pharmachem
Dosage Form : Tablet
Grade : Oral
Dosage Form : Tablet
Grade : Oral
Brand Name : Magnesium Stearate
Application : Lubricants & Glidants
Excipient Details : Magnesium stearate is the magnesium salt of stearic acid. It acts as a lubricating agent and stabilizer in tablet manufacturing.
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Zhejiang Huakang Pharmaceutical
FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]Excipients by Applications
Topical
Evonik's CDMO solutions for APIs and HPAPIs: It specializes where the client needs it most!
Application : Topical
Excipient Details : L-Lysine HCl is used in semi-solid dosage forms such as creams, lotions, shampoos, etc.
Pharmacopoeia Ref : NA
Technical Specs : Molecular weight: 182.7 g/mol
Ingredient(s) : L Lysine HCl Excipient
Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.
Dosage Form : Capsule, Cream / Lotion / Ointment, Gel, Tablet
Grade : Oral, Topical
Category : Surfactant & Foaming Agents
Application : Surfactant & Foaming Agents
Excipient Details : Vitamin E TPGS, a multirole excipient, acts as a surfactant in various oral and topical dosage forms.
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Cream / Lotion / Ointment, Ophthalmic Solution
Grade : Topical, Parenteral
Category : Solubilizers, Topical
Application : Solubilizers, Topical
Excipient Details : Syntadex 7702 is used as a solubilizer in ophthalmic drug products and in topical formulations such as creams, lotions, and ointments.
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Cream / Lotion / Ointment, Suspension, Solution, Syrup
Grade : Topical, Oral
Category : Rheology Modifiers, Thickeners and Stabilizers, Topical
Application : Rheology Modifiers, Thickeners and Stabilizers, Topical
Excipient Details : Xantural 11000 is used as a stabilizer and rheology modifier in oral dosage forms such as syrups, suspensions & solutions & in topical formulations.
Jai Radhe Sales is your partner for all your sourcing needs.
Dosage Form : Cream / Lotion / Ointment
Grade : Topical
Category : Emulsifying Agents, Solubilizers, Surfactant & Foaming Agents, Topical
Application : Emulsifying Agents, Solubilizers, Surfactant & Foaming Agents, Topical
Excipient Details : Polysorbate 80 is a nonionic surfactant and emulsifier often used topical dosage forms such as cream, lotion, ointment, etc.
Nippon provides high-performance, high-value-added cosmetic, pharmaceutical, and industrial raw materials.
Dosage Form : Cream / Lotion / Ointment, Emulsion, Injectable / Parenteral
Grade : Topical, Parenteral
Category : Emulsifying Agents, Parenteral, Solubilizers, Surfactant & Foaming Agents, Topical
Application : Emulsifying Agents, Parenteral, Solubilizers, Surfactant & Foaming Agents, Topical
Excipient Details : Cholesterol is used as emulsifier, solubilizer, surfactant in parenteral and topical formulations such as cream, lotion and ointments.
Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.
Dosage Form : Emulsion
Grade : Topical
Category : Emulsifying Agents, Surfactant & Foaming Agents, Topical
Brand Name : Polyoxyl 25 Cetostearyl Ether
Application : Emulsifying Agents, Surfactant & Foaming Agents, Topical
Excipient Details : Cetostearyl alcohol polyoxyethylene (25) ether is used as a surfactant and emulsifying agent in topical formulations, mainly in emulsions.
Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.
Dosage Form : Capsule, Cream / Lotion / Ointment, Emulsion, Gel, Injectable / Parenteral, Suspension, Tablet
Grade : Parenteral, Oral, Topical
Category : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical
Application : Emulsifying Agents, Film Formers & Plasticizers, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical
Excipient Details : Polysorbate 80 is used as a plasticizer, solubilizer, emulsifier, surfactant, and suspension stabilizer. It is also used in parenteral products.
Nanjing Well is focused on R&D, production & sales of Pharmaceutical Excipients & Synthetic Lubricating base oils.
Dosage Form : Cream / Lotion / Ointment, Emulsion, Gel, Injectable / Parenteral, Suspension, Tablet
Grade : Parenteral, Oral, Topical
Category : Emulsifying Agents, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical
Application : Emulsifying Agents, Parenteral, Solubilizers, Surfactant & Foaming Agents, Thickeners and Stabilizers, Topical
Excipient Details : Polysorbate 20 is used in parenteral products such as biologics. It is used as a solubilizer, surfactant, emulsifier & suspension stabilizer.
DKSH is your trusted partner for companies looking to grow their business in Asia & beyond.
Dosage Form : Capsule, Emulsion, Solution, Suspension, Tablet
Grade : Parenteral, Oral, Topical
Category : Fillers, Diluents & Binders, Lubricants & Glidants, Parenteral, Topical
Application : Fillers, Diluents & Binders, Lubricants & Glidants, Parenteral, Topical
Excipient Details : Captex 300 is used in parenteral solutions and suspensions, topical emulsions, and as filler and lubricant in capsules and tablets.
Pharmacopoeia Ref : EP, USP/NF, JP, US FDA
Technical Specs : LOW C6
Ingredient(s) : Glyceryl Tricaprylate Excipient
Solubilizers
Fillers, Diluents & Binders
Thickeners and Stabilizers
Parenteral
Direct Compression
Emulsifying Agents
Coating Systems & Additives
Disintegrants & Superdisintegrants
Film Formers & Plasticizers
Lubricants & Glidants
Granulation
Surfactant & Foaming Agents
Co-Processed Excipients
Controlled & Modified Release
Taste Masking
Rheology Modifiers
Chewable & Orodispersible Aids
Empty Capsules
API Stability Enhancers
Coloring Agents
Dry Powder Inhalation
Soft Gelatin
Digital Content
DATA COMPILATION #PharmaFlow
NEWS #PharmaBuzz
Global Sales Information
US Medicaid Prescriptions
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