Levomepromazine Maleate

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

16 API Suppliers, 1 USDMF, 5 CEP/COS, 3 JDMF, 1 EU WC, 10 Listed Suppliers

DEVELOPMENTS

2 Drug(s) in Development

2 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports, API Imports

INTERMEDIATES

8 Suppliers

8 Suppliers

DOSSIERs // Finished Dosage Formulations

35 Dossiers, 1 FDA Orange Book, 15 Europe, 10 Canada, 9 Listed Dossiers

GLOBAL SALES INFORMATION

10 Finished Drug Prices

10 Finished Drug Prices

MARKET PLACE

3 APIs, 4 DOSSIERS // FDF

ANALYTICAL SOLUTION(s)

2 EDQM Standards, 1 USP Standards

DIGITAL CONTENT

2 News

2 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

399

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 7104-38-3, Methotrimeprazine maleate, Levo mepromazine maleate, Milezin, Minozinan, Neuractil

Molecular Formula

C₂₃H₂₈N₂O₅S

Molecular Weight

444.5 g/mol

InChI Key

IFLZPECPTYCEBR-VIEYUMQNSA-N

FDA UNII

5KN5Y9V01K

1 2D Structure

Levomepromazine Maleate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(Z)-but-2-enedioic acid;(2R)-3-(2-methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine

2.1.2 InChI

InChI=1S/C19H24N2OS.C4H4O4/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21;5-3(6)1-2-4(7)8/h5-11,14H,12-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-;/m1./s1

2.1.3 InChI Key

IFLZPECPTYCEBR-VIEYUMQNSA-N

2.1.4 Canonical SMILES

CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)OC)CN(C)C.C(=CC(=O)O)C(=O)O

2.1.5 Isomeric SMILES

C[C@@H](CN1C2=CC=CC=C2SC3=C1C=C(C=C3)OC)CN(C)C.C(=C\C(=O)O)\C(=O)O

2.2 Other Identifiers

2.2.1 UNII

5KN5Y9V01K

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 7104-38-3

2. Methotrimeprazine Maleate

3. Levo Mepromazine Maleate

4. Milezin

5. Minozinan

6. Neuractil

7. Neurocil

8. Sofmin

9. Levomepromazine Hydrogen Maleate

10. Hirnamin

11. Nozinan

12. Tisercin

13. Veractil

14. Levomepromazinum

15. 5kn5y9v01k

16. Methoprazine

17. (2r)-3-(2-methoxyphenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine Maleate

18. (z)-but-2-enedioic Acid;(2r)-3-(2-methoxyphenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine

19. Methotrimeprazine Maleat Salt

20. Unii-5kn5y9v01k

21. Levomepromazinmaleat

22. Hirnamin (tn)

23. Einecs 230-412-8

24. Levomepromazine Maleate [usan:jan]

25. Ncgc00016681-01

26. Cas-7104-38-3

27. Dsstox_cid_25399

28. Dsstox_rid_80853

29. Dsstox_gsid_45399

30. Schembl218717

31. Levomepromazinum [hpus]

32. Chembl1725730

33. Dtxsid4045399

34. Hms1570o16

35. Hms2097o16

36. Hms3714o16

37. Levomepromazine Maleate [mi]

38. Tox21_110559

39. Levomepromazine Maleate [jan]

40. Levomepromazine Maleate [usan]

41. Akos025116974

42. Levomepromazine Maleate (jp17/usan)

43. Ccg-220797

44. Levomepromazine Maleate [mart.]

45. Levomepromazine Maleate [who-dd]

46. 10h-phenothiazine-10-propanamine, 2-methoxy-n,n,.beta.-trimethyl-, (.beta.r)-, (2z)-2-butenedioate (1:1)

47. Cs-0455065

48. L0299

49. Levomepromazine Maleate [ep Monograph]

50. D02248

51. 104l383

52. Sr-01000872673

53. Sr-01000872673-1

54. Q27262488

55. Levomepromazine Maleate 1.0 Mg/ml In Methanol (as Free Base)

56. (betar)-2-methoxy-n,n,beta-trimethyl-10h-phenothiazine-10-propanamine (2z)-2-butenedioate

57. (r)-3-(2-methoxy-10h-phenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine Maleate

58. But-2-enedioic Acid;(2r)-3-(2-methoxyphenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine

59. (2r)-3-(2-methoxy-10h-phenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine (2z)-but-2-enedioate

60. (2r)-3-(2-methoxy-10h-phenothiazin-10-yl)-n,n,2-trimethylpropan-1-amine Hydrogen (2z)-but-2-enedioate

61. 10h-phenothiazine-10-propanamine, 2-methoxy-n,n,beta-trimethyl-, (betar)-, (2z)-2-butenedioate (1:1)

2.4 Create Date

2005-10-11

3 Chemical and Physical Properties

Molecular Formula	C₂₃H₂₈N₂O₅S
Molecular Weight	444.5 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	7
Exact Mass	444.17189317 g/mol
Monoisotopic Mass	444.17189317 g/mol
Topological Polar Surface Area	116 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	497
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2