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Chemistry

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Also known as: 203120-17-6, R-125489, (2r,3r,4s)-3-acetamido-4-(diaminomethylideneamino)-2-[(1r,2r)-2,3-dihydroxy-1-methoxypropyl]-3,4-dihydro-2h-pyran-6-carboxylic acid, B408iw3gl5, Laninamivir (inn), D-glycero-d-galacto-non-2-enonic acid, 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-7-o-methyl-
Molecular Formula
C13H22N4O7
Molecular Weight
346.34  g/mol
InChI Key
QNRRHYPPQFELSF-CNYIRLTGSA-N
FDA UNII
B408IW3GL5

Laninamivir
Laninamivir has been used in trials studying the treatment of Influenza.
1 2D Structure

Laninamivir

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3R,4S)-3-acetamido-4-(diaminomethylideneamino)-2-[(1R,2R)-2,3-dihydroxy-1-methoxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
2.1.2 InChI
InChI=1S/C13H22N4O7/c1-5(19)16-9-6(17-13(14)15)3-8(12(21)22)24-11(9)10(23-2)7(20)4-18/h3,6-7,9-11,18,20H,4H2,1-2H3,(H,16,19)(H,21,22)(H4,14,15,17)/t6-,7+,9+,10+,11+/m0/s1
2.1.3 InChI Key
QNRRHYPPQFELSF-CNYIRLTGSA-N
2.1.4 Canonical SMILES
CC(=O)NC1C(C=C(OC1C(C(CO)O)OC)C(=O)O)N=C(N)N
2.1.5 Isomeric SMILES
CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@@H]([C@@H](CO)O)OC)C(=O)O)N=C(N)N
2.2 Other Identifiers
2.2.1 UNII
B408IW3GL5
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 5-(acetylamino)-4-((aminoiminomethyl)amino)-2,6-anhydro-3,4,5-trideoxy-7-o-methyl-d-glycero-d-galacto-non-2-enonic Acid

2. Laninamivir Octanoate

3. Laninamivir Octanoate Hydrate

4. Laninamivir Octanoate Monohydrate

5. Laninamivir Trifluoroacetate

6. R 125489

7. R-125489

8. R125489

2.3.2 Depositor-Supplied Synonyms

1. 203120-17-6

2. R-125489

3. (2r,3r,4s)-3-acetamido-4-(diaminomethylideneamino)-2-[(1r,2r)-2,3-dihydroxy-1-methoxypropyl]-3,4-dihydro-2h-pyran-6-carboxylic Acid

4. B408iw3gl5

5. Laninamivir (inn)

6. D-glycero-d-galacto-non-2-enonic Acid, 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-7-o-methyl-

7. Laninamivir [inn]

8. (2r,3r,4s)-3-acetamido-2-((1r,2r)-2,3-dihydroxy-1-methoxypropyl)-4-guanidino-3,4-dihydro-2h-pyran-6-carboxylic Acid

9. (4s,5r,6r)-5-acetamido-4-carbamimidamido-6-((1r,2r)-3-hydroxy-2-methoxypropyl)-5,6-dihydro-4h-pyran-2-carboxylic Acid

10. 5-(acetylamino)-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-o-methyl-d-glycero-d-galacto-non-2-enonic Acid

11. Laninamivir [inn:jan]

12. Laninamivir (cs-8958)

13. Unii-b408iw3gl5

14. Lani

15. Laninamivir [mi]

16. Laninamivir [mart.]

17. Laninamivir [who-dd]

18. Chembl466246

19. Schembl12284832

20. Dtxsid60942457

21. Chebi:177801

22. Bcpp000190

23. Glxc-15033

24. Bcp27633

25. Ex-a4019

26. Zinc3985629

27. Bdbm50009296

28. Akos015850995

29. Akos032947260

30. Bcp9000836

31. Db12791

32. (2r,3r,4s)-3-acetamido-2-[(1r,2r)-2,3-dihydroxy-1-methoxy-propyl]-4-guanidino-3,4-dihydro-2h-pyran-6-carboxylic Acid

33. (4s,5r,6r)-5-acetamido-4-guanidino-6-((1r,2r)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4h-pyran-2-carboxylic Acid

34. Ac-36457

35. Hy-14818

36. Cs-0003575

37. C21557

38. D09410

39. 120l176

40. A814430

41. Q6487096

42. R 125489r 125489

43. (4s,5r,6r)-5-acetamido-4-guanidino-6- ((1r,2r)-2,3-dihydroxy-1-methoxypropyl)-5,6-dihydro-4h-pyran-2-carboxylic Acid

44. 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-7-o-methyl-d-glycero-d-galacto-non-2-enonic Acid

45. 5-acetylamino-4-(diaminomethyl-amino)-6-(2,3-dihydroxy-1-methoxy-propyl)-5,6-dihydro-4h-pyran-2-carboxylic Acid

2.4 Create Date
2005-08-01
3 Chemical and Physical Properties
Molecular Weight 346.34 g/mol
Molecular Formula C13H22N4O7
XLogP3-3.2
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass346.14884905 g/mol
Monoisotopic Mass346.14884905 g/mol
Topological Polar Surface Area190 Ų
Heavy Atom Count24
Formal Charge0
Complexity532
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antiviral Agents

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)


4.2 ATC Code

J - Antiinfectives for systemic use

J05 - Antivirals for systemic use

J05A - Direct acting antivirals

J05AH - Neuraminidase inhibitors

J05AH04 - Laninamivir


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Looking for 203120-17-6 / Laninamivir API manufacturers, exporters & distributors?

Laninamivir manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Laninamivir API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Laninamivir manufacturer or Laninamivir supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Laninamivir manufacturer or Laninamivir supplier.

PharmaCompass also assists you with knowing the Laninamivir API Price utilized in the formulation of products. Laninamivir API Price is not always fixed or binding as the Laninamivir Price is obtained through a variety of data sources. The Laninamivir Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Laninamivir

Synonyms

203120-17-6, R-125489, (2r,3r,4s)-3-acetamido-4-(diaminomethylideneamino)-2-[(1r,2r)-2,3-dihydroxy-1-methoxypropyl]-3,4-dihydro-2h-pyran-6-carboxylic acid, B408iw3gl5, Laninamivir (inn), D-glycero-d-galacto-non-2-enonic acid, 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-7-o-methyl-

Cas Number

203120-17-6

Unique Ingredient Identifier (UNII)

B408IW3GL5

About Laninamivir

Laninamivir has been used in trials studying the treatment of Influenza.

Laninamivir Manufacturers

A Laninamivir manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Laninamivir, including repackagers and relabelers. The FDA regulates Laninamivir manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Laninamivir API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Laninamivir Suppliers

A Laninamivir supplier is an individual or a company that provides Laninamivir active pharmaceutical ingredient (API) or Laninamivir finished formulations upon request. The Laninamivir suppliers may include Laninamivir API manufacturers, exporters, distributors and traders.

Laninamivir GMP

Laninamivir Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Laninamivir GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Laninamivir GMP manufacturer or Laninamivir GMP API supplier for your needs.

Laninamivir CoA

A Laninamivir CoA (Certificate of Analysis) is a formal document that attests to Laninamivir's compliance with Laninamivir specifications and serves as a tool for batch-level quality control.

Laninamivir CoA mostly includes findings from lab analyses of a specific batch. For each Laninamivir CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Laninamivir may be tested according to a variety of international standards, such as European Pharmacopoeia (Laninamivir EP), Laninamivir JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Laninamivir USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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