Find L-Ergothioneine manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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EU WC

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Chemistry

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Also known as: L-(+)-ergothioneine, 497-30-3, L-ergothioneine, Sympectothion, Ergothionine, L-thioneine
Molecular Formula
C9H15N3O2S
Molecular Weight
229.30  g/mol
InChI Key
SSISHJJTAXXQAX-ZETCQYMHSA-N
FDA UNII
BDZ3DQM98W

L-Ergothioneine
A naturally occurring metabolite of HISTIDINE that has antioxidant properties.
1 2D Structure

L-Ergothioneine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)-2-(trimethylazaniumyl)propanoate
2.1.2 InChI
InChI=1S/C9H15N3O2S/c1-12(2,3)7(8(13)14)4-6-5-10-9(15)11-6/h5,7H,4H2,1-3H3,(H2-,10,11,13,14,15)/t7-/m0/s1
2.1.3 InChI Key
SSISHJJTAXXQAX-ZETCQYMHSA-N
2.1.4 Canonical SMILES
C[N+](C)(C)C(CC1=CNC(=S)N1)C(=O)[O-]
2.1.5 Isomeric SMILES
C[N+](C)(C)[C@@H](CC1=CNC(=S)N1)C(=O)[O-]
2.2 Other Identifiers
2.2.1 UNII
BDZ3DQM98W
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2 Thiol L Histidine Betaine

2. 2-thiol-l-histidine-betaine

3. Thioneine

2.3.2 Depositor-Supplied Synonyms

1. L-(+)-ergothioneine

2. 497-30-3

3. L-ergothioneine

4. Sympectothion

5. Ergothionine

6. L-thioneine

7. Thiolhistidine-betaine

8. Thioneine

9. (s)-3-(2-thioxo-2,3-dihydro-1h-imidazol-4-yl)-2-(trimethylammonio)propanoate

10. Bdz3dqm98w

11. 58511-63-0

12. L(+)-ergothioneine

13. Thiasine

14. (2s)-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)-2-(trimethylazaniumyl)propanoate

15. (s)-(1-carboxy-2-(2-mercaptoimidazol-4-yl)ethyl)trimethylammonium Hydroxide

16. Unii-bdz3dqm98w

17. Erythrothioneine

18. L-ergothionine

19. Ergothioneine Thiol

20. Ergothioneine Thione

21. Nsc 7175

22. Thiolhistidinebetaine

23. Einecs 207-843-5

24. Mfcd00167474

25. Ergothioneine L-(+)

26. Ergothioneine Thione Form

27. Ai3-23492

28. Ergothioneine [mi]

29. Ergothioneine (thione Form)

30. Ergothioneine [inci]

31. Schembl188140

32. Chebi:4828

33. Schembl9985141

34. Chebi:82707

35. Dtxsid901020082

36. Hms2089d04

37. 2-mercaptohistidine Trimethylbetaine

38. Hy-n1914

39. Ccg-207908

40. 1h-imidazole-4-ethanaminium, .alpha.-carboxy-2,3-dihydro-n,n,n-trimethyl-2-thioxo-, Inner Salt, (.alpha.s)-

41. 1h-imidazole-4-ethanaminium, Alpha-carboxy-2,3-dihydro-n,n,n-trimethyl-2-thioxo-, Inner Salt, (s)-

42. Cs-0018211

43. D83035

44. Ab01275464-01

45. A930109

46. Ergothionine;l-(+)-ergothioneine;erythrothioneine

47. Q614788

48. (2s)-3-(2-mercapto-1h-imidazol-5-yl)-2-(trimethylammonio)propanoate

49. (2s)-3-(2-mercapto-1h-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate

50. 3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)-2-trimethylammonio-propanoate

51. Nalpha,nalpha,nalpha-trimethyl-2-sulfanylidene-2,3-dihydro-l-histidine

52. (2s)-3-(2-sulfanylidene-2,3-dihydro-1h-imidazol-4-yl)-2-(trimethylazaniumyl)propanoate

53. (2s)-3-(2-thioxo-2,3-dihydro-1h-imidazol-4-yl)-2-(trimethylazaniumyl)propanoate

54. (.alpha.s)-.alpha.-carboxy-2,3-dihydro-n,n,n-trimethyl-2-thioxo-1h-imidazole-4-ethanaminium Inner Salt

55. (alphas)-alpha-carboxy-2,3-dihydro-n,n,n-trimethyl-2-thioxo-1h-imidazole-4-ethanaminium Inner Salt

56. 1h-imidazole-4-ethanaminium, Alpha-carboxy-2,3-dihydro-n,n,n-trimethyl-2-thioxo-, Hydroxide, Inner Salt, (s)-

57. 1h-imidazole-4-ethanaminium, Alpha-carboxy-2,3-dihydro-n,n,n-trimethyl-2-thioxo-, Inner Salt, (alphas)-

58. 1h-imidazole-4-ethaniminium, Alpha-carboxy-2,3-dihydro-n,n,n-trimethyl-2-thioxo-, Hydroxide, Inner Salt, (s)-

59. Ammonium, (1-carboxy-2-(2-mercaptoimidazol-4-yl)ethyl)trimethyl-, Hydroxide, Inner Salt, L-(+)-

2.4 Create Date
2006-02-02
3 Chemical and Physical Properties
Molecular Weight 229.30 g/mol
Molecular Formula C9H15N3O2S
XLogP30.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area96.3
Heavy Atom Count15
Formal Charge0
Complexity314
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antioxidants

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)


API SUPPLIERS

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01

Comhony Biotech

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothComhony Biotech manufactures fermentation & semi-synthetic APIs which aim at dermatology, anti-biotics; mitochondria & memory health.

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02

KansenBio

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ELCC
Not Confirmed
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KansenBio

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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ELCC
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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Sichuan Benepure Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ELCC
Not Confirmed
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04

Anthem Biosciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ELCC
Not Confirmed
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05

Suzhou Ryway Biotech

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

ELCC
Not Confirmed
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Listed Suppliers

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  • WHO-GMP

Virtual BoothComhony Biotech manufactures fermentation & semi-synthetic APIs which aim at dermatology, anti-biotics; mitochondria & memory health.

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Digital Content Digital Content

Ergothioneine

About the Company : Comhony Biotech supplies APIs and nutraceutical ingredients to pharmaceutical and nutraceutical clients worldwide. Using proprietary technologies, the company manufactures fermenta...

Comhony Biotech supplies APIs and nutraceutical ingredients to pharmaceutical and nutraceutical clients worldwide. Using proprietary technologies, the company manufactures fermentation and semi-synthetic products for dermatology and antibiotics (APIs), as well as mitochondria and memory health (nutraceuticals). Comhony’s manufacturing facility is approved by the NMPA (CFDA) and complies with Chinese GMP standards, equivalent to EU, WHO, and ICH/Q7 GMP requirements. Note: Product(s) under patent(s) are offered only for R&D purposes as per the Patent Act & not for commercial sale.
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02

ELCC
Not Confirmed
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L-Ergothioneine

About the Company : Anthem Biosciences is a leading contract research and innovation service provider (CRISP) in Bengaluru, India, which manufactures novel drug actives. Established in 2007, it specia...

Anthem Biosciences is a leading contract research and innovation service provider (CRISP) in Bengaluru, India, which manufactures novel drug actives. Established in 2007, it specializes in both biological and chemistry-based products and services. It has a strong track record in drug and product development, and supports development, optimization and testing of various compounds including proteins, monoclonal antibodies, peptides, large & small molecules and toxins. Inspected by USFDA, Japan’s PMDA, EU QPs, it develops nutritional products using organic synthesis and offers quality control and regulatory compliance assistance to clients.
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KansenBio

China
ELCC
Not Confirmed
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KansenBio

China
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ELCC
Not Confirmed

Ergothioneine

About the Company : KansenBio is a pioneering biotechnology company founded in 2022 as a spin-off from Tsinghua University, dedicated to creating a healthier, greener future through nature-inspired bi...

KansenBio is a pioneering biotechnology company founded in 2022 as a spin-off from Tsinghua University, dedicated to creating a healthier, greener future through nature-inspired biotech innovation. We build advanced, low-carbon manufacturing platforms using industrial fermentation, strain engineering, and AI to develop high-value bio-based products for cosmetics, food, pharmaceuticals, and sustainable materials. With a strong scientific team and commitment to sustainability, KansenBio delivers eco-friendly solutions that drive progress in health, beauty, and bio-manufacturing.
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ELCC
Not Confirmed
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L-Ergothioneine

About the Company : Benepure is a global research, manufacture and supplier of ingredients and their derivatives for healthcare industry. It owns strong research and development team, cutting-edge equ...

Benepure is a global research, manufacture and supplier of ingredients and their derivatives for healthcare industry. It owns strong research and development team, cutting-edge equipment, high-standard manufacturing base and philosophy of professional service, devoted to offering new products and innovative services in varied fields of pharmaceutical, functional food, cosmetics and feed industries. Our objective: we strive to provide high-standard products and professional services with higher efficiency and more convenience . we’ll never stop trying for humans’ health.
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05

ELCC
Not Confirmed
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L-Ergothioneine

About the Company : Suzhou Ryway Biotech Co., Ltd. is located in Suzhou of Jiangsu Provice. It is a comprehensive enterprise integrated of product research, manufacturing, marketing and service. There...

Suzhou Ryway Biotech Co., Ltd. is located in Suzhou of Jiangsu Provice. It is a comprehensive enterprise integrated of product research, manufacturing, marketing and service. There is strong technical strength, advanced testing method, precision manufacturing equipment. Main products are medical intermediate and fine chemicals. The product is popular among domestic users. In addition, they have been exported to Southeast Asia, Europe and America regions. Our operation tenet is “quality first, customer first”. We constantly improve our market competitiveness. We expect to cooperate with wide colleagues and create brilliance together.
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Drugs in Development

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  • Development Update

Details:

Whey Protein is a protein drug, which is currently being evaluated in clinical studies for the treatment of aging.


Lead Product(s): Whey Protein,Creatine Monohydrate,Fucoidan,Urolithin A,Nicotinamide Mononucleotide,Multivitamin,L-Ergothioneine

Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed

Study Phase: UndisclosedProduct Type: Protein

Sponsor: Xprize Foundation | Abinopharm Inc | DoNotAge.org

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable March 05, 2026

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National University of Singapore

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ELCC
Not Confirmed

National University of Singapore

Country
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ELCC
Not Confirmed

Details : Whey Protein is a protein drug, which is currently being evaluated in clinical studies for the treatment of aging.

Product Name : Undisclosed

Product Type : Protein

Upfront Cash : Inapplicable

March 05, 2026

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  • Development Update

Details:

Ergothioneine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.


Lead Product(s): L-Ergothioneine,Inapplicable

Therapeutic Area: Undisclosed Brand Name: Undisclosed

Study Phase: UndisclosedProduct Type: Amino Acid

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable March 20, 2025

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Shanghai EGT Synbio Group Co., Ltd.

Country
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ELCC
Not Confirmed

Shanghai EGT Synbio Group Co., Ltd.

Country
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ELCC
Not Confirmed

Details : Ergothioneine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.

Product Name : Undisclosed

Product Type : Amino Acid

Upfront Cash : Inapplicable

March 20, 2025

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  • Development Update

Details:

Ergothioneine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.


Lead Product(s): L-Ergothioneine,Inapplicable

Therapeutic Area: Undisclosed Brand Name: Undisclosed

Study Phase: UndisclosedProduct Type: Amino Acid

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 13, 2021

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Natural Immune Systems Inc

Country
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ELCC
Not Confirmed

Natural Immune Systems Inc

Country
arrow
ELCC
Not Confirmed

Details : Ergothioneine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.

Product Name : Undisclosed

Product Type : Amino Acid

Upfront Cash : Inapplicable

September 13, 2021

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  • Development Update

Details:

L-Ergothioneine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.


Lead Product(s): L-Ergothioneine,Inapplicable

Therapeutic Area: Undisclosed Brand Name: Undisclosed

Study Phase: UndisclosedProduct Type: Amino Acid

Sponsor: Blue California Company

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 21, 2020

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04

Midwest Center for Metabolic and Cardiovascular Research

Country
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ELCC
Not Confirmed

Midwest Center for Metabolic and Cardiovascular Research

Country
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ELCC
Not Confirmed

Lead Product(s) : L-Ergothioneine,Inapplicable

Therapeutic Area : Undisclosed

Highest Development Status : Undisclosed

Partner/Sponsor/Collaborator : Blue California Company

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : L-Ergothioneine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of undefined medical condition.

Product Name : Undisclosed

Product Type : Amino Acid

Upfront Cash : Inapplicable

September 21, 2020

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ABOUT THIS PAGE

Looking for 497-30-3 / L-Ergothioneine API manufacturers, exporters & distributors?

L-Ergothioneine manufacturers, exporters & distributors 1

52

PharmaCompass offers a list of L-Ergothioneine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right L-Ergothioneine manufacturer or L-Ergothioneine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred L-Ergothioneine manufacturer or L-Ergothioneine supplier.

PharmaCompass also assists you with knowing the L-Ergothioneine API Price utilized in the formulation of products. L-Ergothioneine API Price is not always fixed or binding as the L-Ergothioneine Price is obtained through a variety of data sources. The L-Ergothioneine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

L-Ergothioneine

Synonyms

L-(+)-ergothioneine, 497-30-3, Sympectothion, Ergothionine, L-thioneine, Thiolhistidine-betaine

Cas Number

497-30-3

Unique Ingredient Identifier (UNII)

BDZ3DQM98W

About L-Ergothioneine

A naturally occurring metabolite of HISTIDINE that has antioxidant properties.

L-Ergothioneine Manufacturers

A L-Ergothioneine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of L-Ergothioneine, including repackagers and relabelers. The FDA regulates L-Ergothioneine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. L-Ergothioneine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of L-Ergothioneine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

L-Ergothioneine Suppliers

A L-Ergothioneine supplier is an individual or a company that provides L-Ergothioneine active pharmaceutical ingredient (API) or L-Ergothioneine finished formulations upon request. The L-Ergothioneine suppliers may include L-Ergothioneine API manufacturers, exporters, distributors and traders.

click here to find a list of L-Ergothioneine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

L-Ergothioneine GMP

L-Ergothioneine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of L-Ergothioneine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right L-Ergothioneine GMP manufacturer or L-Ergothioneine GMP API supplier for your needs.

L-Ergothioneine CoA

A L-Ergothioneine CoA (Certificate of Analysis) is a formal document that attests to L-Ergothioneine's compliance with L-Ergothioneine specifications and serves as a tool for batch-level quality control.

L-Ergothioneine CoA mostly includes findings from lab analyses of a specific batch. For each L-Ergothioneine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

L-Ergothioneine may be tested according to a variety of international standards, such as European Pharmacopoeia (L-Ergothioneine EP), L-Ergothioneine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (L-Ergothioneine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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