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Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

2 API Suppliers, 2 USDMF, 4 NDC API

DOSSIERs // Finished Dosage Formulations

8 Dossiers, 4 FDA Orange Book, 2 Europe, 1 Canada, 1 Australia

RELATED EXCIPIENT COMPANIES

Suppliers, 15 Kerry, 7 Microlex e.U, 6 Roquette, 5 Gangwal Healthcare, 3 Sigachi Industries, 3 SPI Pharma, 2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 2 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 2 DFE Pharma, 2 Ingredion Pharma Solutions, 1 Vasa Pharmachem, 1 Aeon Procare, 1 Prachin Chemical, 1 Nanjing Well Pharmaceutical, 1 Seppic, 1 DKSH, 1 Gangwal Chemicals

EXCIPIENTS BY APPLICATIONS

34 Fillers, Diluents & Binders, 12 Direct Compression, 10 Lubricants & Glidants, 6 Co-Processed Excipients, 5 Granulation, 5 Disintegrants & Superdisintegrants, 3 Controlled & Modified Release, 3 Chewable & Orodispersible Aids, 3 Taste Masking, 2 Coating Systems & Additives, 2 Thickeners and Stabilizers, 1 Film Formers & Plasticizers, 1 Emulsifying Agents, 1 Parenteral

GLOBAL SALES INFORMATION

6 US Medicaid Prescriptions, 1 Finished Drug Prices

MARKET PLACE

1 APIs

1 APIs

ANALYTICAL SOLUTION(s)

1 USP Standards, 1 Other Ref. Standards

DIGITAL CONTENT

1 Data Compilations & Company Tracker #PharmaFlow, 2 News

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INTERMEDIATES

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USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

1.00

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25.00

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Also known as: 826-39-1, Inversine, Mevasin, Mecamylamine (hydrochloride), Mevasine, Mecamylamine hcl

Molecular Formula

C₁₁H₂₂ClN

Molecular Weight

203.75 g/mol

InChI Key

PKVZBNCYEICAQP-UHFFFAOYSA-N

FDA UNII

4956DJR58O

1 2D Structure

INCRELEX

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine;hydrochloride

2.1.2 InChI

InChI=1S/C11H21N.ClH/c1-10(2)8-5-6-9(7-8)11(10,3)12-4;/h8-9,12H,5-7H2,1-4H3;1H

2.1.3 InChI Key

PKVZBNCYEICAQP-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC1(C2CCC(C2)C1(C)NC)C.Cl

2.2 Other Identifiers

2.2.1 UNII

4956DJR58O

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 826-39-1

2. Inversine

3. Mevasin

4. Mecamylamine (hydrochloride)

5. Mevasine

6. Mecamylamine Hcl

7. N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine Hydrochloride

8. Mecamylamine, Hcl

9. N,2,3,3-tetramethyl-2-norbornanamine Hydrochloride

10. Nsc-757086

11. Mecamylamine Hydrochloride [usp]

12. 4956djr58o

13. Bicyclo(2.2.1)heptan-2-amine, N,2,3,3-tetramethyl-, Hydrochloride

14. Mekamin Hydrochloride

15. Mecamine Hydrochloride

16. Mecamylamine Hydrochloride (usp)

17. Vecamyl

18. Sr-01000075329

19. Einecs 212-555-8

20. 3-methylaminoisocamphane Hydrochloride

21. 3-methylaminoisokamfan Chlorid [czech]

22. Inversin

23. N-methyl-dl-isobornylamine Hydrochloride

24. Inversene

25. N,2,2,3-tetramethylbicyclo[2.2.1]heptan-3-amine;hydrochloride

26. 3-methylaminoisokamfan Chlorid

27. Unii-4956djr58o

28. Cpdb 0059

29. Inversine (tn)

30. Mecamylamine Chloride

31. 2-norbornanamine, N,2,3,3-tetramethyl-, Hydrochloride

32. N-methyl-n-2,5-endomethylene-1,6,6-trimethylcyclohexylamine Hydrochloride

33. Atg-3

34. Schembl123951

35. Chebi:6707

36. Chembl1237082

37. Niosh/rb7466510

38. Agi-004

39. Atg-003

40. Dtxsid70896795

41. Hms1571o04

42. Pharmakon1600-01500374

43. Hy-b1395

44. Tox21_500841

45. Ccg-39679

46. Mfcd00151462

47. Nsc757086

48. Akos015963326

49. Asa 185/13

50. Lp00841

51. Mecamylamine Hydrochloride [mi]

52. Nsc 757086

53. 2-(methylamino)isocamphane Hydrochloride

54. Ncgc00094171-01

55. Ncgc00094171-02

56. Ncgc00094171-03

57. Ncgc00261526-01

58. Ac-19862

59. Ls-14021

60. Mecamylamine Hydrochloride [mart.]

61. Mecamylamine Hydrochloride [vandf]

62. Mecamylamine Hydrochloride [usp-rs]

63. Mecamylamine Hydrochloride [who-dd]

64. 2-[1,2,4]triazol-1-ylmethyl-benzoicacid

65. Db-056643

66. Cs-0013122

67. Eu-0100841

68. Ft-0603516

69. Ft-0670962

70. Ft-0670963

71. Ft-0670964

72. Rb74665100

73. D00611

74. M 9020

75. Mecamylamine Hydrochloride [orange Book]

76. Mecamylamine Hydrochloride [usp Monograph]

77. N,2,3,3-tetramethyl-2-norcamphanamine Hydrochloride

78. Q-201341

79. Sr-01000075329-1

80. Sr-01000075329-6

81. Q27259230

82. 2-(methylamino)-2,3,3-trimethylnorbornane Hydrochloride

83. Mecamylamine Hydrochloride 100 Microg/ml In Acetonitrile

84. N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine;hydrochloride

85. Norbornane, 2-(methylamino)-2,3,3-trimethyl-, Hydrochloride

86. Bicyclo[2.2.1]heptan-2-amine, N,2,3,3-tetramethyl-, Hydrochloride (1:1)

2.4 Create Date

2005-03-27

3 Chemical and Physical Properties

Molecular Formula	C₁₁H₂₂ClN
Molecular Weight	203.75 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	203.1440774 g/mol
Monoisotopic Mass	203.1440774 g/mol
Topological Polar Surface Area	12 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	197
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	3
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Mecamylamine hydrochloride
Active Ingredient	Mecamylamine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	2.5mg
Market Status	Prescription
Company	Nexgen Pharma

2 of 2
Drug Name	Mecamylamine hydrochloride
Active Ingredient	Mecamylamine hydrochloride
Dosage Form	Tablet
Route	Oral
Strength	2.5mg
Market Status	Prescription
Company	Nexgen Pharma

5 Pharmacology and Biochemistry

5.1 FDA Pharmacological Classification

5.1.1 Pharmacological Classes

Decreased Autonomic Ganglionic Activity [PE]; Autonomic Ganglionic Blocker [EPC]

Find Mecamylamine Hydrochloride manufacturers, exporters & distributors on PharmaCompass

INCRELEX

INCRELEX

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

2 API Suppliers

2 USDMF

4 NDC API

DOSSIERs // Finished Dosage Formulations

8 Dossiers

4 FDA Orange Book

2 Europe

1 Canada

1 Australia

RELATED EXCIPIENT COMPANIES

Suppliers

15 Kerry

7 Microlex e.U

6 Roquette

5 Gangwal Healthcare

3 Sigachi Industries

3 SPI Pharma

2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

2 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

2 DFE Pharma

2 Ingredion Pharma Solutions

1 Vasa Pharmachem

1 Aeon Procare

1 Prachin Chemical

1 Nanjing Well Pharmaceutical

1 Seppic

1 DKSH

1 Gangwal Chemicals

EXCIPIENTS BY APPLICATIONS

34 Fillers, Diluents & Binders

12 Direct Compression

10 Lubricants & Glidants

6 Co-Processed Excipients

5 Granulation

5 Disintegrants & Superdisintegrants

3 Controlled & Modified Release

3 Chewable & Orodispersible Aids

3 Taste Masking

2 Coating Systems & Additives

2 Thickeners and Stabilizers

1 Film Formers & Plasticizers

1 Emulsifying Agents

1 Parenteral

GLOBAL SALES INFORMATION

6 US Medicaid Prescriptions

1 Finished Drug Prices

MARKET PLACE

1 APIs

ANALYTICAL SOLUTION(s)

1 USP Standards

1 Other Ref. Standards

DIGITAL CONTENT

1 Data Compilations & Company Tracker #PharmaFlow

2 News

API SUPPLIERS

API REF. PRICE (USD / KG)

INTERMEDIATES

DOSSIERS // FDF

GLOBAL SALES (USD Million)

EXCIPIENTS

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

REF STANDARD

SERVICES

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