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    Also known as: 31121-93-4, Ibuprofen sodium salt, Sodium ibuprofen, Sodium 2-(4-isobutylphenyl)propionate, Sodium 2-[4-(2-methylpropyl)phenyl]propanoate, Ibuprofen sodium anhydrous
    Molecular Formula
    C13H17NaO2
    Molecular Weight
    228.26  g/mol
    InChI Key
    PTTPUWGBPLLBKW-UHFFFAOYSA-M
    FDA UNII
    O0PJ4UZ01U
    Ibuprofen Sodium
    Ibuprofen Sodium is the sodium salt form of ibuprofen, a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Upon administration, ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
    1 2D Structure

    Ibuprofen Sodium

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    sodium;2-[4-(2-methylpropyl)phenyl]propanoate
    2.1.2 InChI
    InChI=1S/C13H18O2.Na/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;/h4-7,9-10H,8H2,1-3H3,(H,14,15);/q;+1/p-1
    2.1.3 InChI Key
    PTTPUWGBPLLBKW-UHFFFAOYSA-M
    2.1.4 Canonical SMILES
    CC(C)CC1=CC=C(C=C1)C(C)C(=O)[O-].[Na+]
    2.2 Other Identifiers
    2.2.1 UNII
    O0PJ4UZ01U
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 31121-93-4

    2. Ibuprofen Sodium Salt

    3. Sodium Ibuprofen

    4. Sodium 2-(4-isobutylphenyl)propionate

    5. Sodium 2-[4-(2-methylpropyl)phenyl]propanoate

    6. Ibuprofen Sodium Anhydrous

    7. P-isobutylhydratropic Acid Sodium Salt

    8. Sodium 2-(4-isobutylphenyl)propanoate

    9. Ibuprofen (sodium)

    10. Sodium;2-[4-(2-methylpropyl)phenyl]propanoate

    11. O0pj4uz01u

    12. Ibuprofensodiumsalt

    13. Einecs 250-477-6

    14. Unii-o0pj4uz01u

    15. Esprenit (tn)

    16. Sodium Ibuprofen Salt

    17. Hydratropic Acid, P-isobutyl-, Sodium Salt

    18. Benzeneacetic Acid, Alpha-methyl-4-(2-methylpropyl)-, Sodium Salt

    19. Schembl139269

    20. Chembl1241153

    21. Dtxsid4040501

    22. Smsf0005424

    23. Hy-78131c

    24. Sodium2-(4-isobutylphenyl)propanoate

    25. Akos015994627

    26. Cb08098

    27. Hs-0087

    28. Sodium 2-(4'-isobutylphenyl)propionate

    29. 5264-06-2

    30. Bim-0005680.p001

    31. Cs-0031024

    32. 2-(p-isobutylphenyl)propionic Acid Sodium Salt

    33. D08059

    34. ((c)i)-ibuprofen-d3, Sodium Salt (

    35. A-methyl-d3)

    36. W-110791

    37. Q27285172

    38. Benzeneacetic Acid, .alpha.-methyl-4-(2-methylpropyl)-, Sodium Salt (1:1)

    39. Benzeneacetic Acid, .alpha.-methyl-4-(2-methylpropyl)-,sodium Salt

    2.4 Create Date
    2006-02-02
    3 Chemical and Physical Properties
    Molecular Weight 228.26 g/mol
    Molecular Formula C13H17NaO2
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count2
    Rotatable Bond Count4
    Exact Mass228.11262406 g/mol
    Monoisotopic Mass228.11262406 g/mol
    Topological Polar Surface Area40.1 Ų
    Heavy Atom Count16
    Formal Charge0
    Complexity208
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count1
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 FDA Pharmacological Classification
    4.1.1 Pharmacological Classes
    Cyclooxygenase Inhibitors [MoA]; Nonsteroidal Anti-inflammatory Drug [EPC]; Anti-Inflammatory Agents, Non-Steroidal [CS]

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REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"1269.00","actualQuantity":"1269","unit":"KGS","unitRateFc":"37.6","totalValueFC":"62520.2","currency":"USD","unitRateINR":"3669","date":"09-Nov-2021","totalValueINR":"4655961","totalValueInUsd":"62520.2","indian_port":"JNPT","hs_no":"29420012","bill_no":"6171308","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"H.NO. 8-2-337, BESIDE TV9 OFFICE, ROAD NO.3, BANJARA HILLS, Contact N"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670178600,"product":"51224063 IBUPROFEN SODIUM DIHYDRATE 50 KG BATCH NO SB1F0061( FOR EXCIPIENT USE ONLY )","address":"H.NO. 8-2-337, BESIDE TV9 OFFICE, ROAD NO.3, BANJARA HILLS, Contact N","city":"HYDERABAD","supplier":"BASF","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"296.66","actualQuantity":"296.66","unit":"KGS","unitRateFc":"36.2","totalValueFC":"11609.9","currency":"USD","unitRateINR":"3225","date":"05-Dec-2022","totalValueINR":"956728.5","totalValueInUsd":"11609.9","indian_port":"JNPT","hs_no":"29420012","bill_no":"3603757","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"H.NO. 8-2-337, BESIDE TV9 OFFICE, ROAD NO.3, BANJARA HILLS, Contact N"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1700505000,"product":"51224063 IBUPROFEN SODIUM DIHYDRATE 50 KG FIBRE DRUMS (BATCHNO:SB2F0004)","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"BASF","supplierCountry":"HONG KONG","foreign_port":"HOUSTON","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"900.00","actualQuantity":"900","unit":"KGS","unitRateFc":"32.4","totalValueFC":"34856.1","currency":"USD","unitRateINR":"3225","date":"21-Nov-2023","totalValueINR":"2902500","totalValueInUsd":"34856.1","indian_port":"JNPT","hs_no":"29163990","bill_no":"8871979","productDescription":"API","marketType":"","country":"HONG KONG","selfForZScoreResived":"Pharma Grade","supplierPort":"HOUSTON","supplierAddress":"36\/F TWO TAIKOO PLACE TAIKOO PLACE979 KINGS ROAD,QUARRY BAY,HONG KONG HK","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1702837800,"product":"IBUPROFEN SODIUM DIHYDRATE","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"BASF","supplierCountry":"UNITED STATES","foreign_port":"LOS ANGELES","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"1800.00","actualQuantity":"1800","unit":"KGS","unitRateFc":"32.4","totalValueFC":"69735.5","currency":"USD","unitRateINR":"3225","date":"18-Dec-2023","totalValueINR":"5805000","totalValueInUsd":"69735.5","indian_port":"Madras Sea","hs_no":"29420012","bill_no":"9281825","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"LOS ANGELES","supplierAddress":"36\/F TWO TAIKOO PLACE,979 KINGS ROAD QUARRY BAY,SDNF HK","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727634600,"product":"IBUPROFEN SODIUM DIHYDRATE","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"BASF","supplierCountry":"UNITED STATES","foreign_port":"HOUSTON","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"81.90","actualQuantity":"81.9","unit":"KGS","unitRateFc":"33.5","totalValueFC":"3151.8","currency":"USD","unitRateINR":"3225","date":"30-Sep-2024","totalValueINR":"264127.5","totalValueInUsd":"3151.8","indian_port":"JNPT","hs_no":"29420012","bill_no":"5883981","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"HOUSTON","supplierAddress":"36\/F TWO TAIKOO PLACE, TAIKO PLACE 979 KING\\'S ROAD, QUARRY BAY, HONG KONG HONG KONG","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1727634600,"product":"IBUPROFEN SODIUM DIHYDRATE","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"BASF","supplierCountry":"UNITED STATES","foreign_port":"HOUSTON","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"600.00","actualQuantity":"600","unit":"KGS","unitRateFc":"33.5","totalValueFC":"23090.4","currency":"USD","unitRateINR":"3225","date":"30-Sep-2024","totalValueINR":"1935000","totalValueInUsd":"23090.4","indian_port":"JNPT","hs_no":"29420012","bill_no":"5883981","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"HOUSTON","supplierAddress":"36\/F TWO TAIKOO PLACE, TAIKO PLACE 979 KING\\'S ROAD, QUARRY BAY, HONG KONG HONG KONG","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1736793000,"product":"IBUPROFEN SODIUM DIHYDRATE IBUPROFEN SODIUM DIHYDRATE","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"BASF","supplierCountry":"UNITED STATES","foreign_port":"HOUSTON","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"81.90","actualQuantity":"81.9","unit":"KGS","unitRateFc":"37.2","totalValueFC":"3063.1","currency":"USD","unitRateINR":"3225","date":"14-Jan-2025","totalValueINR":"264127.5","totalValueInUsd":"3063.1","indian_port":"JNPT","hs_no":"29420012","bill_no":"7778780","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"HOUSTON","supplierAddress":"36\/F TWO TAIKOO PLACE, TAIKO PLACE 979 KING\\'S ROAD, QUARRY BAY, HONG KONG HONG KONG","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1736793000,"product":"IBUPROFEN SODIUM DIHYDRATE IBUPROFEN SODIUM DIHYDRATE","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"BASF","supplierCountry":"UNITED STATES","foreign_port":"HOUSTON","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"37.2","totalValueFC":"18700.2","currency":"USD","unitRateINR":"3225","date":"14-Jan-2025","totalValueINR":"1612500","totalValueInUsd":"18700.2","indian_port":"JNPT","hs_no":"29420012","bill_no":"7778780","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"HOUSTON","supplierAddress":"36\/F TWO TAIKOO PLACE, TAIKO PLACE 979 KING\\'S ROAD, QUARRY BAY, HONG KONG HONG KONG","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"}]
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    20-Mar-2025
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    ABOUT THIS PAGE

    Looking for 31121-93-4 / Ibuprofen Sodium API manufacturers, exporters & distributors?

    Ibuprofen Sodium manufacturers, exporters & distributors 1

    88

    PharmaCompass offers a list of Ibuprofen Sodium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ibuprofen Sodium manufacturer or Ibuprofen Sodium supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ibuprofen Sodium manufacturer or Ibuprofen Sodium supplier.

    PharmaCompass also assists you with knowing the Ibuprofen Sodium API Price utilized in the formulation of products. Ibuprofen Sodium API Price is not always fixed or binding as the Ibuprofen Sodium Price is obtained through a variety of data sources. The Ibuprofen Sodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Ibuprofen Sodium

    Synonyms

    31121-93-4, Ibuprofen sodium salt, Sodium ibuprofen, Sodium 2-(4-isobutylphenyl)propionate, Sodium 2-[4-(2-methylpropyl)phenyl]propanoate, Ibuprofen sodium anhydrous

    Cas Number

    31121-93-4

    Unique Ingredient Identifier (UNII)

    O0PJ4UZ01U

    About Ibuprofen Sodium

    Ibuprofen Sodium is the sodium salt form of ibuprofen, a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Upon administration, ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

    Ibuprofen Sodium Dihydrate Manufacturers

    A Ibuprofen Sodium Dihydrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ibuprofen Sodium Dihydrate, including repackagers and relabelers. The FDA regulates Ibuprofen Sodium Dihydrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ibuprofen Sodium Dihydrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Ibuprofen Sodium Dihydrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Ibuprofen Sodium Dihydrate Suppliers

    A Ibuprofen Sodium Dihydrate supplier is an individual or a company that provides Ibuprofen Sodium Dihydrate active pharmaceutical ingredient (API) or Ibuprofen Sodium Dihydrate finished formulations upon request. The Ibuprofen Sodium Dihydrate suppliers may include Ibuprofen Sodium Dihydrate API manufacturers, exporters, distributors and traders.

    click here to find a list of Ibuprofen Sodium Dihydrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Ibuprofen Sodium Dihydrate USDMF

    A Ibuprofen Sodium Dihydrate DMF (Drug Master File) is a document detailing the whole manufacturing process of Ibuprofen Sodium Dihydrate active pharmaceutical ingredient (API) in detail. Different forms of Ibuprofen Sodium Dihydrate DMFs exist exist since differing nations have different regulations, such as Ibuprofen Sodium Dihydrate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Ibuprofen Sodium Dihydrate DMF submitted to regulatory agencies in the US is known as a USDMF. Ibuprofen Sodium Dihydrate USDMF includes data on Ibuprofen Sodium Dihydrate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ibuprofen Sodium Dihydrate USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Ibuprofen Sodium Dihydrate suppliers with USDMF on PharmaCompass.

    Ibuprofen Sodium Dihydrate KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Ibuprofen Sodium Dihydrate Drug Master File in Korea (Ibuprofen Sodium Dihydrate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Ibuprofen Sodium Dihydrate. The MFDS reviews the Ibuprofen Sodium Dihydrate KDMF as part of the drug registration process and uses the information provided in the Ibuprofen Sodium Dihydrate KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Ibuprofen Sodium Dihydrate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Ibuprofen Sodium Dihydrate API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Ibuprofen Sodium Dihydrate suppliers with KDMF on PharmaCompass.

    Ibuprofen Sodium Dihydrate WC

    A Ibuprofen Sodium Dihydrate written confirmation (Ibuprofen Sodium Dihydrate WC) is an official document issued by a regulatory agency to a Ibuprofen Sodium Dihydrate manufacturer, verifying that the manufacturing facility of a Ibuprofen Sodium Dihydrate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Ibuprofen Sodium Dihydrate APIs or Ibuprofen Sodium Dihydrate finished pharmaceutical products to another nation, regulatory agencies frequently require a Ibuprofen Sodium Dihydrate WC (written confirmation) as part of the regulatory process.

    click here to find a list of Ibuprofen Sodium Dihydrate suppliers with Written Confirmation (WC) on PharmaCompass.

    Ibuprofen Sodium Dihydrate NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Ibuprofen Sodium Dihydrate as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Ibuprofen Sodium Dihydrate API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Ibuprofen Sodium Dihydrate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Ibuprofen Sodium Dihydrate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Ibuprofen Sodium Dihydrate NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Ibuprofen Sodium Dihydrate suppliers with NDC on PharmaCompass.

    Ibuprofen Sodium Dihydrate GMP

    Ibuprofen Sodium Dihydrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Ibuprofen Sodium Dihydrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ibuprofen Sodium Dihydrate GMP manufacturer or Ibuprofen Sodium Dihydrate GMP API supplier for your needs.

    Ibuprofen Sodium Dihydrate CoA

    A Ibuprofen Sodium Dihydrate CoA (Certificate of Analysis) is a formal document that attests to Ibuprofen Sodium Dihydrate's compliance with Ibuprofen Sodium Dihydrate specifications and serves as a tool for batch-level quality control.

    Ibuprofen Sodium Dihydrate CoA mostly includes findings from lab analyses of a specific batch. For each Ibuprofen Sodium Dihydrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Ibuprofen Sodium Dihydrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Ibuprofen Sodium Dihydrate EP), Ibuprofen Sodium Dihydrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ibuprofen Sodium Dihydrate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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