Hydronidone

Synopsis, Chemistry

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Also known as: Hydronidone, 851518-71-3, F 351, F-351, N-(4-hydroxyphenyl)-5-methyl-2-1h-pyridone, N-(4-hydroxyphenyl)-5-methyl-2-pyridone

Molecular Formula

C₁₂H₁₁NO₂

Molecular Weight

201.22 g/mol

InChI Key

NETTXQJYJRFTFS-UHFFFAOYSA-N

FDA UNII

RXQ128313W

Hydronidone has antifibrotic activity.

1 2D Structure

Hydronidone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-(4-hydroxyphenyl)-5-methylpyridin-2-one

2.1.2 InChI

InChI=1S/C12H11NO2/c1-9-2-7-12(15)13(8-9)10-3-5-11(14)6-4-10/h2-8,14H,1H3

2.1.3 InChI Key

NETTXQJYJRFTFS-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC1=CN(C(=O)C=C1)C2=CC=C(C=C2)O

2.2 Other Identifiers

2.2.1 UNII

RXQ128313W

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Hydronidone

2. N-(4-hydroxyphenyl)-5-methyl-2-pyridone

2.3.2 Depositor-Supplied Synonyms

1. Hydronidone

2. 851518-71-3

3. F 351

4. F-351

5. N-(4-hydroxyphenyl)-5-methyl-2-1h-pyridone

6. N-(4-hydroxyphenyl)-5-methyl-2-pyridone

7. Rxq128313w

8. F-351;f351

9. 1-(4-hydroxyphenyl)-5-methyl-1h-pyridine-2-one

10. Schembl143564

11. Unii-rxq128313w

12. 1-(4-hydroxyphenyl)-5-methylpyridin-2-one

13. Chembl4297288

14. Dtxsid40459058

15. Zinc21981322

16. Akos016006473

17. Db06299

18. Sb18945

19. F351

20. Db-115847

21. Hy-100438

22. Cs-0019024

23. Ft-0669968

24. Ft-0669969

25. Q27288328

2.4 Create Date

2006-10-26

3 Chemical and Physical Properties

Molecular Formula	C₁₂H₁₁NO₂
Molecular Weight	201.22 g/mol
XLogP3	1.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	201.078978594 g/mol
Monoisotopic Mass	201.078978594 g/mol
Topological Polar Surface Area	40.5 Å²
Heavy Atom Count	15
Formal Charge	0
Complexity	312
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1