HYDROCODONE POLISTIREX

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Also known as: Chlorpheniramine mixture with hydrocodone, 131219-97-1, Vituz, Tuzistra xr, Tussionex pennkinetic, S-t forte 2

Molecular Formula

C₃₄H₄₀ClN₃O₃

Molecular Weight

574.1 g/mol

InChI Key

UUEZOEBHFHYMGR-RNWHKREASA-N

1 2D Structure

HYDROCODONE POLISTIREX

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine

2.1.2 InChI

InChI=1S/C18H21NO3.C16H19ClN2/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3,6,11-12,17H,4-5,7-9H2,1-2H3;3-9,11,15H,10,12H2,1-2H3/t11-,12+,17-,18-;/m0./s1

2.1.3 InChI Key

UUEZOEBHFHYMGR-RNWHKREASA-N

2.1.4 Canonical SMILES

CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(=O)CC4.CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2

2.1.5 Isomeric SMILES

CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4.CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Chlorpheniramine Mixture With Hydrocodone

2. 131219-97-1

3. Vituz

4. Tuzistra Xr

5. Tussionex Pennkinetic

6. S-t Forte 2

7. Tussicaps Extended-release

8. Tussionex

9. Chlorpheniramine / Hydrocodone

10. Chlorpheniramine Polistirex / Hydrocodone Polistirex

11. Chlorpheniramine Polistirex And Hydrocodone Polistirex

12. Hydrocodone Polistirex And Chlorpheniramine Polistirex

13. Schembl2522788

14. Dtxsid50156960

15. Hydrocodone Conbination Product 15 Mg/du

2.3 Create Date

2009-08-20

3 Chemical and Physical Properties

Molecular Formula	C₃₄H₄₀ClN₃O₃
Molecular Weight	574.1 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	573.2758198 g/mol
Monoisotopic Mass	573.2758198 g/mol
Topological Polar Surface Area	54.9 Å²
Heavy Atom Count	41
Formal Charge	0
Complexity	758
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 6
Drug Name	Hydrocodone polistirex and chlorpheniramine polistirex
Active Ingredient	Chlorpheniramine polistirex; hydrocodone polistirex
Dosage Form	Suspension, extended release
Route	Oral
Strength	eq 10mg bitartrate/5ml; eq 8mg maleate/5ml
Market Status	Prescription
Company	Tris Pharma

2 of 6
Drug Name	Tussicaps
Active Ingredient	Chlorpheniramine polistirex; hydrocodone polistirex
Dosage Form	Capsule, extended release
Route	Oral
Strength	eq 10mg bitartrate; eq 5mg bitartrate; eq 4mg maleate; eq 8mg maleate
Market Status	Prescription
Company	Ecr Pharma

3 of 6
Drug Name	Tussionex pennkinetic
PubMed Health	Hydrocodone and Chlorpheniramine Polistirex (Oral route)
Drug Classes	Antitussive, Opioid/Antihistamine Combination, Chlorpheniramine
Active Ingredient	Chlorpheniramine polistirex; hydrocodone polistirex
Dosage Form	Suspension, extended release
Route	Oral
Strength	eq 10mg bitartrate/5ml; eq 8mg maleate/5ml
Market Status	Prescription
Company	Ucb

4 of 6
Drug Name	Hydrocodone polistirex and chlorpheniramine polistirex
Active Ingredient	Chlorpheniramine polistirex; hydrocodone polistirex
Dosage Form	Suspension, extended release
Route	Oral
Strength	eq 10mg bitartrate/5ml; eq 8mg maleate/5ml
Market Status	Prescription
Company	Tris Pharma

5 of 6
Drug Name	Tussicaps
Active Ingredient	Chlorpheniramine polistirex; hydrocodone polistirex
Dosage Form	Capsule, extended release
Route	Oral
Strength	eq 10mg bitartrate; eq 5mg bitartrate; eq 4mg maleate; eq 8mg maleate
Market Status	Prescription
Company	Ecr Pharma

6 of 6
Drug Name	Tussionex pennkinetic
PubMed Health	Hydrocodone and Chlorpheniramine Polistirex (Oral route)
Drug Classes	Antitussive, Opioid/Antihistamine Combination, Chlorpheniramine
Active Ingredient	Chlorpheniramine polistirex; hydrocodone polistirex
Dosage Form	Suspension, extended release
Route	Oral
Strength	eq 10mg bitartrate/5ml; eq 8mg maleate/5ml
Market Status	Prescription
Company	Ucb