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    Chemistry

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    Also known as: 50-01-1, Guanidinium chloride, Guanidine hcl, Guanidine, monohydrochloride, Aminoformamidine hydrochloride, Guanidine;hydrochloride
    Molecular Formula
    CH6ClN3
    Molecular Weight
    95.53  g/mol
    InChI Key
    PJJJBBJSCAKJQF-UHFFFAOYSA-N
    FDA UNII
    3YQC9ZY4YB
    GUANIDINE HYDROCHLORIDE API
    A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
    1 2D Structure

    GUANIDINE HYDROCHLORIDE API

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    guanidine;hydrochloride
    2.1.2 InChI
    InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
    2.1.3 InChI Key
    PJJJBBJSCAKJQF-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C(=N)(N)N.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    3YQC9ZY4YB
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Chloride, Guanidinium

    2. Chloride, Guanidium

    3. Guanidine

    4. Guanidine Monohydrate

    5. Guanidine Monohydrobromide

    6. Guanidine Monohydrochloride

    7. Guanidine Monohydroiodine

    8. Guanidine Nitrate

    9. Guanidine Phosphate

    10. Guanidine Sulfate

    11. Guanidine Sulfate (1:1)

    12. Guanidine Sulfate (2:1)

    13. Guanidine Sulfite (1:1)

    14. Guanidinium

    15. Guanidinium Chloride

    16. Guanidium Chloride

    17. Hydrochloride, Guanidine

    18. Monohydrate, Guanidine

    19. Monohydrobromide, Guanidine

    20. Monohydrochloride, Guanidine

    21. Monohydroiodine, Guanidine

    22. Nitrate, Guanidine

    23. Phosphate, Guanidine

    24. Sulfate, Guanidine

    2.3.2 Depositor-Supplied Synonyms

    1. 50-01-1

    2. Guanidinium Chloride

    3. Guanidine Hcl

    4. Guanidine, Monohydrochloride

    5. Aminoformamidine Hydrochloride

    6. Guanidine;hydrochloride

    7. Aminomethanamidine Hydrochloride

    8. Guanidine (hydrochloride)

    9. Guanidinehydrochloride

    10. Guanidine Monohydrochloride

    11. Guanidine Chloride

    12. Aminoformamidine Hcl

    13. Guanidinium Hydrochloride

    14. 3yqc9zy4yb

    15. Mfcd00013026

    16. Nsc-755884

    17. Guanidinium Chloride;aminoformamidine Hydrochloride

    18. Guanidine Hydrochloride, >=98%

    19. Carbamidine Hydrochloride

    20. Chebi:32735

    21. Usaf Ek-749

    22. Einecs 200-002-3

    23. Unii-3yqc9zy4yb

    24. Guanidine-hcl

    25. Ai3-19014

    26. Ccris 8910

    27. Guanidine.hcl

    28. Guanidine, Hydrochloride (1:1)

    29. Guanidine Hcl Salt

    30. Guandine Hydrochloride

    31. Guanidine Hydrochoride

    32. Guanidine Hydrocloride

    33. Guanidine-hydrochloride

    34. Guanidine.hydrochloride

    35. Guanidine Hydrogen Chloride

    36. Ec 200-002-3

    37. Guanidine Hydrochloride Salt

    38. Guanidine Hcl [inci]

    39. Guanidine Hydrochloride (tn)

    40. Guanidine Hydrochloride, 92%

    41. Chembl1200728

    42. Dtxsid7058757

    43. Guanidine (aminoformamidine) Hcl

    44. Hy-b0178a

    45. Guanidine Hydrochloride, Ultrapure

    46. Pharmakon1600-01300022

    47. Str00188

    48. Guanidine Hydrochloride [ii]

    49. Guanidine Hydrochloride [mi]

    50. Guanidine Hydrochloride, >=99.5%

    51. Nsc755884

    52. S4070

    53. Guanidine Hydrochloride, P.a., 99%

    54. Akos008901146

    55. Guanidine-[13c,15n3] Hydrochloride

    56. Ccg-266024

    57. Cs-2056

    58. Guanidine Hydrochloride [mart.]

    59. Guanidine Hydrochloride [vandf]

    60. Nsc 755884

    61. Guanidine Hydrochloride [usp-rs]

    62. Guanidine Hydrochloride [who-dd]

    63. Guanidine Hydrochloride, >=99.0% (at)

    64. Ft-0626822

    65. G0162

    66. G0197

    67. Guanidine Hydrochloride [orange Book]

    68. Sw220255-1

    69. D11626

    70. Guanidine Hydrochloride, Molecular Biology Grade

    71. A827930

    72. Q415903

    73. J-200345

    74. Guanidine Hydrochloride, For Molecular Biology, >=99%

    75. Guanidine Hydrochloride, Saj Special Grade, >=99.0%

    76. F0001-1302

    77. Guanidine Hydrochloride Solution, 8 M In H2o (filtered)

    78. Guanidine Hydrochloride Solution, Bioultra, ~8 M In H2o

    79. Guanidine Hydrochloride, Bioxtra, >=99.5% (titration)

    80. Guanidine Hydrochloride, 99.5+%, Molecular Biology Grade

    81. Guanidine Hydrochloride, Vetec(tm) Reagent Grade, >=98%

    82. Guanidine Hydrochloride, 99+% Organic Base And Chaeotropic Agent

    83. Guanidine Hydrochloride, Anhydrous, Free-flowing, Redi-dri(tm), >=99%

    84. Guanidine Hydrochloride, Bioultra, For Molecular Biology, >=99.5% (at)

    85. Aminoformamidine Hydrochloride, Aminomethanamidine Hydrochloride, Guanidinium Chloride

    86. Guanidine Hydrochloride, >=99% (titration), Organic Base And Chaeotropic Agent

    87. Guanidine Hydrochloride, Pharmagrade, Manufactured Under Appropriate Controls For Use As A Raw Material In Pharma Or Biopharmaceutical Production.

    2.4 Create Date
    2005-07-19
    3 Chemical and Physical Properties
    Molecular Weight 95.53 g/mol
    Molecular Formula CH6ClN3
    Hydrogen Bond Donor Count4
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count0
    Exact Mass95.0250249 g/mol
    Monoisotopic Mass95.0250249 g/mol
    Topological Polar Surface Area75.9 Ų
    Heavy Atom Count5
    Formal Charge0
    Complexity26.3
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2

    API Reference Price

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V. ROAD","city":"MUMBAI,MAHARASHTRA.","supplier":"HANGZHOU MINKO CHEMICAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"UNICHEM LABORATORIES LIMITED","customerCountry":"INDIA","quantity":"20000.00","actualQuantity":"20000","unit":"KGS","unitRateFc":"3.7","totalValueFC":"75876","currency":"USD","unitRateINR":"324.8","date":"01-Apr-2025","totalValueINR":"6495120","totalValueInUsd":"75876","indian_port":"JNPT","hs_no":"29280090","bill_no":"9222538","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"200B, GUODU DEVELOPMENT MANSION, NO .182 ZHAOHUI ROAD, HANGZHOU Hangzho u - 310014, , China China","customerAddress":"UNICHEM BHAVAN, S. V. ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1743705000,"product":"DIORTHOTOLYL GUANIDINE ( DOTG) OIL FREE GRADE IUPAC NAME-1,3-DI-(2-METHYLPHENYL ) GUANIDINE CAS NO.-97-39-2DIORTHOTOLYL GUANIDINE ( DOTG) OIL FREE GRADE","address":"PLOT NO.157,G.I.D.C.","city":"GUJARAT ,GUJARAT","supplier":"KAIRI INTERNATIONAL (HK) LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"K PATEL DYE-CHEM INDUSTRIES PRIVATE LIMITED","customerCountry":"INDIA","quantity":"2500.00","actualQuantity":"2500","unit":"KGS","unitRateFc":"8.5","totalValueFC":"21484.3","currency":"USD","unitRateINR":"735.6","date":"04-Apr-2025","totalValueINR":"1839097.6","totalValueInUsd":"21484.3","indian_port":"JNPT","hs_no":"29215990","bill_no":"9291990","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ROOM F8\/F WANG CHEONG BUILDINGNO.25 1 RECLAMATION 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CHINA","customerAddress":"Floor No.22, Plot No.1, Survey No.83\/1, Galaxy Tower"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1744050600,"product":"AMINOGUANIDINE BICARBONATE (OR) AMINOGUANIDINE HYDROGENCARBONATEAMINOGUANIDINE BICARBONATE (OR) AMINOGUANIDINE HYDROGEN","address":"Floor No.22, Plot No.1, Survey No.83\/1, Galaxy Tower","city":"Hyderabad","supplier":"JIANGSU GTIG HUATAI CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"APITORIA PHARMA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"9500.00","actualQuantity":"9500","unit":"KGS","unitRateFc":"3.8","totalValueFC":"36521","currency":"USD","unitRateINR":"329.1","date":"08-Apr-2025","totalValueINR":"3126260","totalValueInUsd":"36521","indian_port":"Vizag Sea","hs_no":"29262000","bill_no":"9364251","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"15-16\/F HUACHANG ORIENTAL PLAZA RENMIN ROAD ZHANGJIAGANG CITY JIANGSU CHINA","customerAddress":"Floor No.22, Plot No.1, Survey No.83\/1, Galaxy Tower"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1744223400,"product":"AMINOGUANIDINE BICARBONATE 99% MIN AMINOGUANIDINE BICARBONATE 99% MIN","address":"28\/A, IDA,","city":"HYDERABAD, AP","supplier":"ZHEJIANG TONGXIANG FOREIGN TRADE (GROUP) COLTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"ARAGEN LIFE SCIENCES LIMITED","customerCountry":"INDIA","quantity":"6000.00","actualQuantity":"6000","unit":"KGS","unitRateFc":"3.2","totalValueFC":"19442.6","currency":"USD","unitRateINR":"277.4","date":"10-Apr-2025","totalValueINR":"1664325","totalValueInUsd":"19442.6","indian_port":"Madras Sea","hs_no":"29280090","bill_no":"9408649","productDescription":"API","marketType":"REGULATED 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    ABOUT THIS PAGE

    Looking for 50-01-1 / GUANIDINE HYDROCHLORIDE API API manufacturers, exporters & distributors?

    GUANIDINE HYDROCHLORIDE API manufacturers, exporters & distributors 1

    34

    PharmaCompass offers a list of GUANIDINE HYDROCHLORIDE API API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right GUANIDINE HYDROCHLORIDE API manufacturer or GUANIDINE HYDROCHLORIDE API supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred GUANIDINE HYDROCHLORIDE API manufacturer or GUANIDINE HYDROCHLORIDE API supplier.

    PharmaCompass also assists you with knowing the GUANIDINE HYDROCHLORIDE API API Price utilized in the formulation of products. GUANIDINE HYDROCHLORIDE API API Price is not always fixed or binding as the GUANIDINE HYDROCHLORIDE API Price is obtained through a variety of data sources. The GUANIDINE HYDROCHLORIDE API Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    GUANIDINE HYDROCHLORIDE API

    Synonyms

    50-01-1, Guanidinium chloride, Guanidine hcl, Guanidine, monohydrochloride, Aminoformamidine hydrochloride, Guanidine;hydrochloride

    Cas Number

    50-01-1

    Unique Ingredient Identifier (UNII)

    3YQC9ZY4YB

    About GUANIDINE HYDROCHLORIDE API

    A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.

    GUANIDINE HYDROCHLORIDE API Manufacturers

    A GUANIDINE HYDROCHLORIDE API manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of GUANIDINE HYDROCHLORIDE API, including repackagers and relabelers. The FDA regulates GUANIDINE HYDROCHLORIDE API manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. GUANIDINE HYDROCHLORIDE API API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of GUANIDINE HYDROCHLORIDE API manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    GUANIDINE HYDROCHLORIDE API Suppliers

    A GUANIDINE HYDROCHLORIDE API supplier is an individual or a company that provides GUANIDINE HYDROCHLORIDE API active pharmaceutical ingredient (API) or GUANIDINE HYDROCHLORIDE API finished formulations upon request. The GUANIDINE HYDROCHLORIDE API suppliers may include GUANIDINE HYDROCHLORIDE API API manufacturers, exporters, distributors and traders.

    click here to find a list of GUANIDINE HYDROCHLORIDE API suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    GUANIDINE HYDROCHLORIDE API USDMF

    A GUANIDINE HYDROCHLORIDE API DMF (Drug Master File) is a document detailing the whole manufacturing process of GUANIDINE HYDROCHLORIDE API active pharmaceutical ingredient (API) in detail. Different forms of GUANIDINE HYDROCHLORIDE API DMFs exist exist since differing nations have different regulations, such as GUANIDINE HYDROCHLORIDE API USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A GUANIDINE HYDROCHLORIDE API DMF submitted to regulatory agencies in the US is known as a USDMF. GUANIDINE HYDROCHLORIDE API USDMF includes data on GUANIDINE HYDROCHLORIDE API's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The GUANIDINE HYDROCHLORIDE API USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of GUANIDINE HYDROCHLORIDE API suppliers with USDMF on PharmaCompass.

    GUANIDINE HYDROCHLORIDE API JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The GUANIDINE HYDROCHLORIDE API Drug Master File in Japan (GUANIDINE HYDROCHLORIDE API JDMF) empowers GUANIDINE HYDROCHLORIDE API API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the GUANIDINE HYDROCHLORIDE API JDMF during the approval evaluation for pharmaceutical products. At the time of GUANIDINE HYDROCHLORIDE API JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of GUANIDINE HYDROCHLORIDE API suppliers with JDMF on PharmaCompass.

    GUANIDINE HYDROCHLORIDE API GMP

    GUANIDINE HYDROCHLORIDE API Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of GUANIDINE HYDROCHLORIDE API GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right GUANIDINE HYDROCHLORIDE API GMP manufacturer or GUANIDINE HYDROCHLORIDE API GMP API supplier for your needs.

    GUANIDINE HYDROCHLORIDE API CoA

    A GUANIDINE HYDROCHLORIDE API CoA (Certificate of Analysis) is a formal document that attests to GUANIDINE HYDROCHLORIDE API's compliance with GUANIDINE HYDROCHLORIDE API specifications and serves as a tool for batch-level quality control.

    GUANIDINE HYDROCHLORIDE API CoA mostly includes findings from lab analyses of a specific batch. For each GUANIDINE HYDROCHLORIDE API CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    GUANIDINE HYDROCHLORIDE API may be tested according to a variety of international standards, such as European Pharmacopoeia (GUANIDINE HYDROCHLORIDE API EP), GUANIDINE HYDROCHLORIDE API JP (Japanese Pharmacopeia) and the US Pharmacopoeia (GUANIDINE HYDROCHLORIDE API USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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