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Chemistry

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Also known as: 161967-81-3, Raxar, Grepafloxacin hcl, Grepafloxacin hydrochloride [usan], Opc-17116, A4er1z8n9n
Molecular Formula
C19H23ClFN3O3
Molecular Weight
395.9  g/mol
InChI Key
IEPMBYOIQGCVHO-UHFFFAOYSA-N
FDA UNII
A4ER1Z8N9N

Grepafloxacin
1 2D Structure

Grepafloxacin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;hydrochloride
2.1.2 InChI
InChI=1S/C19H22FN3O3.ClH/c1-10-8-22(6-5-21-10)15-7-14-16(11(2)17(15)20)18(24)13(19(25)26)9-23(14)12-3-4-12;/h7,9-10,12,21H,3-6,8H2,1-2H3,(H,25,26);1H
2.1.3 InChI Key
IEPMBYOIQGCVHO-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1CN(CCN1)C2=C(C(=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)C)F.Cl
2.2 Other Identifiers
2.2.1 UNII
A4ER1Z8N9N
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (+--)-1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid

2. (+--)-1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Monohydrochloride

3. 3-quinolinecarboxylic Acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-

4. 3-quinolinecarboxylic Acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-, Monohydrochloride, (+--)-

5. Grepafloxacin

6. Grepafloxacin Hcl

7. Opc 17116

8. Opc-17116

9. Raxar

2.3.2 Depositor-Supplied Synonyms

1. 161967-81-3

2. Raxar

3. Grepafloxacin Hcl

4. Grepafloxacin Hydrochloride [usan]

5. Opc-17116

6. A4er1z8n9n

7. Grepafloxacin (hydrochloride)

8. 173689-78-6

9. 161967-81-3 (hcl)

10. 1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid Hydrochloride

11. Opc 17116

12. Dsstox_cid_26692

13. Dsstox_rid_81826

14. Dsstox_gsid_46692

15. 1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic Acid;hydrochloride

16. Opc 17116; Raxar; Vaxar; Dl-grepafloxacin Hydrochloride

17. 1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-2,3-dihydroquinoline-3-carboxylic A

18. Cas-161967-81-3

19. Ncgc00167527-01

20. Unii-a4er1z8n9n

21. Lungaskin

22. Vaxar

23. Gpfx

24. Raxar (tn)

25. Schembl137804

26. Chembl1200393

27. Dtxsid0046692

28. Hy-a0147a

29. Grepafloxacin Hydrochloride (+-)-

30. Tox21_112524

31. Akos015962215

32. Tox21_112524_1

33. Grepafloxacin Hydrochloride (jan/usan)

34. Grepafloxacin Hydrochloride [mi]

35. Ncgc00167527-03

36. Ac-16082

37. Grepafloxacin Hydrochloride [mart.]

38. Grepafloxacin Hydrochloride [vandf]

39. Grepafloxacin Hydrochloride [who-dd]

40. Cs-0031245

41. D02178

42. Grepafloxacin Hydrochloride [orange Book]

43. 967g813

44. Q27273620

45. (+-)-1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Monohydrochloride

46. (+/-)-1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Monohydrochloride

47. 3-quinolinecarboxylic Acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-, Monohydrochloride, (+-)-

48. 3-quinolinecarboxylic Acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-, Monohydrochloride

49. 3-quinolinecarboxylic Acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-, Monohydrochloride, (+-)-

50. 3-quinolinecarboxylic Acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-, Monohydrochloride, (+/-)-

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 395.9 g/mol
Molecular Formula C19H23ClFN3O3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Exact Mass395.1411975 g/mol
Monoisotopic Mass395.1411975 g/mol
Topological Polar Surface Area72.9 Ų
Heavy Atom Count27
Formal Charge0
Complexity636
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


Topoisomerase II Inhibitors

Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. (See all compounds classified as Topoisomerase II Inhibitors.)


Patents & EXCLUSIVITIES

Check the patents & exclusivity for this product

ABOUT THIS PAGE

Looking for 161967-81-3 / Grepafloxacin API manufacturers, exporters & distributors?

Grepafloxacin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Grepafloxacin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Grepafloxacin manufacturer or Grepafloxacin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Grepafloxacin manufacturer or Grepafloxacin supplier.

PharmaCompass also assists you with knowing the Grepafloxacin API Price utilized in the formulation of products. Grepafloxacin API Price is not always fixed or binding as the Grepafloxacin Price is obtained through a variety of data sources. The Grepafloxacin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Grepafloxacin

Synonyms

161967-81-3, Raxar, Grepafloxacin hcl, Grepafloxacin hydrochloride [usan], Opc-17116, A4er1z8n9n

Cas Number

161967-81-3

Unique Ingredient Identifier (UNII)

A4ER1Z8N9N

GREPAFLOXACIN HYDROCHLORIDE Manufacturers

A GREPAFLOXACIN HYDROCHLORIDE manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of GREPAFLOXACIN HYDROCHLORIDE, including repackagers and relabelers. The FDA regulates GREPAFLOXACIN HYDROCHLORIDE manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. GREPAFLOXACIN HYDROCHLORIDE API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

GREPAFLOXACIN HYDROCHLORIDE Suppliers

A GREPAFLOXACIN HYDROCHLORIDE supplier is an individual or a company that provides GREPAFLOXACIN HYDROCHLORIDE active pharmaceutical ingredient (API) or GREPAFLOXACIN HYDROCHLORIDE finished formulations upon request. The GREPAFLOXACIN HYDROCHLORIDE suppliers may include GREPAFLOXACIN HYDROCHLORIDE API manufacturers, exporters, distributors and traders.

GREPAFLOXACIN HYDROCHLORIDE GMP

GREPAFLOXACIN HYDROCHLORIDE Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of GREPAFLOXACIN HYDROCHLORIDE GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right GREPAFLOXACIN HYDROCHLORIDE GMP manufacturer or GREPAFLOXACIN HYDROCHLORIDE GMP API supplier for your needs.

GREPAFLOXACIN HYDROCHLORIDE CoA

A GREPAFLOXACIN HYDROCHLORIDE CoA (Certificate of Analysis) is a formal document that attests to GREPAFLOXACIN HYDROCHLORIDE's compliance with GREPAFLOXACIN HYDROCHLORIDE specifications and serves as a tool for batch-level quality control.

GREPAFLOXACIN HYDROCHLORIDE CoA mostly includes findings from lab analyses of a specific batch. For each GREPAFLOXACIN HYDROCHLORIDE CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

GREPAFLOXACIN HYDROCHLORIDE may be tested according to a variety of international standards, such as European Pharmacopoeia (GREPAFLOXACIN HYDROCHLORIDE EP), GREPAFLOXACIN HYDROCHLORIDE JP (Japanese Pharmacopeia) and the US Pharmacopoeia (GREPAFLOXACIN HYDROCHLORIDE USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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