X
API Suppliers
0
US DMFs Filed
0
CEP/COS Certifications
0
JDMFs Filed
0
Other Certificates
0
Other Suppliers
0
0
USA (Orange Book)
0
Europe
0
Canada
0
Australia
0
South Africa
0
Uploaded Dossiers
0
U.S. Medicaid
0
Annual Reports
0
0
USFDA Orange Book Patents
0
USFDA Exclusivities
0
Blog #PharmaFlow
0
News
0
EDQM
0
USP
0
JP
0
Other Listed Suppliers
0
0
1. 1,3-dimethylol-5,5-dimethylhydantoin
2. Dmdm Hydantoin
1. 6440-58-0
2. Dmdm Hydantoin
3. Dimethyloldimethyl Hydantoin
4. Dmdmh
5. Glydant
6. 1,3-bis(hydroxymethyl)-5,5-dimethylhydantoin
7. 1,3-dimethylol-5,5-dimethylhydantoin
8. Dimethylol-5,5-dimethylhydantoin
9. Dimethyloldimethylhydantoin
10. 2,4-imidazolidinedione, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
11. 1,3-bis(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione
12. Byr0546tow
13. 1,3-dihydroxymethyl-5,5-dimethylhydantoin
14. Mfcd00467199
15. 1,3-dimethylol-5,5-dimethyl-hydantoin
16. Dantoin-dmdmh
17. Glycoserve-dmdmh
18. Dantoin Dmdmh 55
19. Dmdmh 55
20. Caswell No. 273ab
21. Einecs 229-222-8
22. Unii-byr0546tow
23. Epa Pesticide Chemical Code 115501
24. Brn 0882348
25. 1,3-di(hydroxymethyl)-5,5-dimethylhydantoin
26. Hsdb 7488
27. 1,3-dihydroxylmethyl-5,5-dimethylhydantoin
28. Ec 229-222-8
29. Dimethylol Dimethyl Hydantoin
30. Dmdm Hydantoin [ii]
31. Dsstox_cid_15217
32. Dsstox_gsid_35217
33. Schembl69185
34. Hydantoin, 1,3-bis(hydroxymethyl)-5,5-dimethyl-
35. Dmdm Hydantoin [inci]
36. Dmdm Hydantion [vandf]
37. Dmdm Hydantoin [vandf]
38. Dtxsid8035217
39. Zinc2033948
40. Tox21_303842
41. Akos006345746
42. Cs-w021276
43. Ncgc00356947-01
44. As-10924
45. Sy101650
46. Cas-6440-58-0
47. Ft-0606699
48. H11751
49. 440b580
50. A834743
51. Q5205613
52. W-104844
53. 1,3-dimethylol-5,5-dimethylhydantoin [hsdb]
54. 1,3-bis (hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
55. 1,3 Bis(hydroxymethyl)-5,5- Dimethylhydantoindimethylhydantoin
56. 5-ethyl-1,3-dihydroxy-5-methyl-imidazolidine-2,4-dione;1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione
| Molecular Weight | 188.18 g/mol |
|---|---|
| Molecular Formula | C7H12N2O4 |
| XLogP3 | -0.2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 188.07970687 g/mol |
| Monoisotopic Mass | 188.07970687 g/mol |
| Topological Polar Surface Area | 81.1 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 251 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
A 0.1 mL aqueous solution containing 0.1 mCi of 1,3-dihydroxymethyl-5,5'-dimethylhydantoin-5-(14)-C was applied to the middorsal area of young adult male Sprague-Dawley rats. After 72 hours, more than 90% of the applied dose was recovered; more than 98% of the recovered activity was confined to the dose site. At the time of killing, less than 1% of the radioactivity was distributed in all body tissues. The higher counts of radioactivity were reported for the gastrointestinal tract, liver, and bone marrow. For most tissue samples, there was no evidence of accumulation of DMDM Hydantoin or its metabolites. DMDM Hydantoin and its metabolites are excreted primarily via the urine. The amount of (14)C activity in the urine decreased approximately 6 times over a 72-hour period; radioactivity in the feces remained approximately constant and significantly below that of the urine.
Cosmetic Ingredient Review Panel; Final Report on the Safety Assessment of DMDM Hydantoin. J Am Coll Toxicol 7 (3): 245-77 (1988)
Market Place
