Gentamicin

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

20 API Suppliers, 13 USDMF, 2 CEP/COS, 3 JDMF, 1 KDMF, 10 NDC API, 7 Listed Suppliers

DEVELOPMENTS

9 Drug(s) in Development

9 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Exports, FDF Imports

DOSSIERs // Finished Dosage Formulations

312 Dossiers, 123 FDA Orange Book, 85 Europe, 19 Canada, 1 Australia, 36 South Africa, 48 Listed Dossiers

DRUG PRODUCT COMPOSITION

SUSPENSION/DROPS;OPHTHALMIC - EQ 0.3% BASE;1%, OINTMENT;OPHTHALMIC - EQ 0.3% BASE;0.6%

SUSPENSION/DROPS;OPHTHALMIC - EQ 0.3% BASE;1%
OINTMENT;OPHTHALMIC - EQ 0.3% BASE;0.6%

RELATED EXCIPIENT COMPANIES

Suppliers, 11 Roquette, 6 BASF, 5 Actylis, 5 Corel Pharma Chem, 3 Nanjing Well Pharmaceutical, 3 Kerry, 3 Microlex e.U, 2 Ideal Cures Pvt Ltd, 2 Gangwal Healthcare, 2 SPI Pharma, 2 Gangwal Chemicals, 2 Finar, 1 Curia, 1 Rochem International Inc, 1 DKSH, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

16 Coating Systems & Additives, 12 Film Formers & Plasticizers, 9 Parenteral, 9 Fillers, Diluents & Binders, 6 Topical, 4 Taste Masking, 4 Solubilizers, 4 Controlled & Modified Release, 3 Lubricants & Glidants, 3 Thickeners and Stabilizers, 2 Direct Compression, 2 Surfactant & Foaming Agents, 2 Chewable & Orodispersible Aids, 1 Disintegrants & Superdisintegrants, 1 API Stability Enhancers, 1 Granulation, 1 Soft Gelatin, 1 Emulsifying Agents, 1 Co-Processed Excipients

GLOBAL SALES INFORMATION

21 US Medicaid Prescriptions, 89 Finished Drug Prices

MARKET PLACE

53 APIs, 12 DOSSIERS // FDF

ANALYTICAL SOLUTION(s)

1 BioAnalytical Methods, 3 EDQM Standards, 1 USP Standards, 2 Other Ref. Standards

DIGITAL CONTENT

1 Data Compilations & Company Tracker #PharmaFlow, 22 News

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

123

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

114.00

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: Garamycin solution, Gentimicin sulfate solution, Gentamicin sulfate, 500x solution, Akos015895526, G0383

Molecular Formula

C₂₁H₄₅N₅O₁₁S

Molecular Weight

575.7 g/mol

InChI Key

NWQISSNHRDDWRM-UHFFFAOYSA-N

1 2D Structure

Gentamicin

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid

2.1.2 InChI

InChI=1S/C21H43N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;(H2,1,2,3,4)

2.1.3 InChI Key

NWQISSNHRDDWRM-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC.OS(=O)(=O)O

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Garamycin Solution

2. Gentimicin Sulfate Solution

3. Gentamicin Sulfate, 500x Solution

4. Akos015895526

5. G0383

2.3 Create Date

2009-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₄₅N₅O₁₁S
Molecular Weight	575.7 g/mol
Hydrogen Bond Donor Count	10
Hydrogen Bond Acceptor Count	16
Rotatable Bond Count	7
Exact Mass	575.28362844 g/mol
Monoisotopic Mass	575.28362844 g/mol
Topological Polar Surface Area	283 Å²
Heavy Atom Count	38
Formal Charge	0
Complexity	717
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	13
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Genoptic
PubMed Health	Gentamicin
Drug Classes	Antibacterial, Antibiotic
Active Ingredient	Gentamicin sulfate
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	eq 0.3% base
Market Status	Prescription
Company	Allergan

2 of 2
Drug Name	Genoptic
PubMed Health	Gentamicin
Drug Classes	Antibacterial, Antibiotic
Active Ingredient	Gentamicin sulfate
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	eq 0.3% base
Market Status	Prescription
Company	Allergan

Find Gentamicin Sulfate manufacturers, exporters & distributors on PharmaCompass

Gentamicin

Gentamicin

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

20 API Suppliers

13 USDMF

2 CEP/COS

3 JDMF

1 KDMF

10 NDC API

7 Listed Suppliers

DEVELOPMENTS

9 Drug(s) in Development

PRICE INFORMATION

API Reference Price

API Exports

API Imports

FDF Exports

FDF Imports

DOSSIERs // Finished Dosage Formulations

312 Dossiers

123 FDA Orange Book

85 Europe

19 Canada

1 Australia

36 South Africa

48 Listed Dossiers

DRUG PRODUCT COMPOSITION

SUSPENSION/DROPS;OPHTHALMIC - EQ 0.3% BASE;1%

OINTMENT;OPHTHALMIC - EQ 0.3% BASE;0.6%

RELATED EXCIPIENT COMPANIES

Suppliers

11 Roquette

6 BASF

5 Actylis

5 Corel Pharma Chem

3 Nanjing Well Pharmaceutical

3 Kerry

3 Microlex e.U

2 Ideal Cures Pvt Ltd

2 Gangwal Healthcare

2 SPI Pharma

2 Gangwal Chemicals

2 Finar

1 Curia

1 Rochem International Inc

1 DKSH

1 Shijiazhuang Huaxu Pharmaceutical

1 Zhejiang Huakang Pharmaceutical

EXCIPIENTS BY APPLICATIONS

16 Coating Systems & Additives

12 Film Formers & Plasticizers

9 Parenteral

9 Fillers, Diluents & Binders

6 Topical

4 Taste Masking

4 Solubilizers

4 Controlled & Modified Release

3 Lubricants & Glidants

3 Thickeners and Stabilizers

2 Direct Compression

2 Surfactant & Foaming Agents

2 Chewable & Orodispersible Aids

1 Disintegrants & Superdisintegrants

1 API Stability Enhancers

1 Granulation

1 Soft Gelatin

1 Emulsifying Agents

1 Co-Processed Excipients

GLOBAL SALES INFORMATION

21 US Medicaid Prescriptions

89 Finished Drug Prices

MARKET PLACE

53 APIs

12 DOSSIERS // FDF

ANALYTICAL SOLUTION(s)

1 BioAnalytical Methods

3 EDQM Standards