Find Sodium Fusidate manufacturers, exporters & distributors on PharmaCompass

Fusidate Sodium

Fusidate Sodium

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

13 API Suppliers, 6 USDMF, 10 CEP/COS, 1 JDMF, 1 KDMF, 1 NDC API, 3 Listed Suppliers

DEVELOPMENTS

4 Drug(s) in Development

4 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Exports

DOSSIERs // Finished Dosage Formulations

1 Dossiers, 1 Canada

MARKET PLACE

5 APIs

5 APIs

ANALYTICAL SOLUTION(s)

3 EDQM Standards, 1 Other Ref. Standards

DIGITAL CONTENT

3 News

3 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

653

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: Sodium fusidate, 751-94-0, Fusidic acid sodium salt, Fucidin, Fucidine, Fusidic acid, sodium salt

Molecular Formula

C₃₁H₄₇NaO₆

Molecular Weight

538.7 g/mol

InChI Key

HJHVQCXHVMGZNC-JCJNLNMISA-M

FDA UNII

J7P3696BCQ

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis.

1 2D Structure

Fusidate Sodium

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;(2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoate

2.1.2 InChI

InChI=1S/C31H48O6.Na/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);/q;+1/p-1/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

2.1.3 InChI Key

HJHVQCXHVMGZNC-JCJNLNMISA-M

2.1.4 Canonical SMILES

CC1C2CCC3(C(C2(CCC1O)C)C(CC4C3(CC(C4=C(CCC=C(C)C)C(=O)[O-])OC(=O)C)C)O)C.[Na+]

2.1.5 Isomeric SMILES

C[C@H]1[C@@H]2CC[C@]3([C@H]([C@]2(CC[C@H]1O)C)[C@@H](C[C@@H]\4[C@@]3(C[C@@H](/C4=C(/CCC=C(C)C)\C(=O)[O-])OC(=O)C)C)O)C.[Na+]

2.2 Other Identifiers

2.2.1 UNII

J7P3696BCQ

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Acid, Fusidic

2. Fucithalmic

3. Fusidate, Silver

4. Fusidate, Sodium

5. Fusidic Acid

6. Fusidic Acid, Sodium Salt

7. Fusidin

8. Silver Fusidate

9. Sodium Fusidate

10. Sodium, Fusidate

11. Stanicide

2.3.2 Depositor-Supplied Synonyms

1. Sodium Fusidate

2. 751-94-0

3. Fusidic Acid Sodium Salt

4. Fucidin

5. Fucidine

6. Fusidic Acid, Sodium Salt

7. Fusidic Acid Sodium

8. Fusidate Sodium [usan]

9. Sq 16360

10. Fusidin

11. Fucidin Leo

12. Sq-16360

13. Fusidic Acid (sodium Salt)

14. J7p3696bcq

15. Zn-6

16. Sodium Fusidin

17. Fucidina

18. Fusidate Sodium (usan)

19. Intertulle Fucidin

20. Zn 6-na

21. Mfcd09054714

22. Smr000326707

23. Einecs 212-030-3

24. Oate

25. Unii-j7p3696bcq

26. Sodium Fusitate

27. Fusidicacidsodium

28. Ncgc00017030-01

29. Cas-751-94-0

30. Prestwick_826

31. Fucidin Leo (tn)

32. Sodium Fusidate (jp17)

33. Dsstox_cid_25552

34. Dsstox_rid_80951

35. Dsstox_gsid_45552

36. Schembl74969

37. Mls001076552

38. Mls001333217

39. Mls001333218

40. Mls002153242

41. Mls002207062

42. Sodium 3alpha,11alpha,16beta-trihydroxy-29-nor-8alpha,9beta,13alpha,14beta-dammara-17(20),24-dien-21-oate 16-acetate

43. Sodium Fusidate [jan]

44. Chembl1256987

45. Dtxsid9045552

46. Sodium Fusidate [mart.]

47. Hy-b1350a

48. Fusidate Sodium [who-dd]

49. Hms1569m21

50. Hms2236d08

51. Tox21_110745

52. S4663

53. Akos005146265

54. Fusidic Acid Sodium Salt [mi]

55. Sodium Fusidate [ep Monograph]

56. Ccg-269952

57. Cs-4520

58. Ks-1299

59. 29-nordammara-17(20),24-dien-21-oic Acid, 16-(acetyloxy)-3,11-dihydroxy-, Monosodium Salt, (3.alpha.,4.alpha.,8.alpha.,9.beta.,11.alpha.,13.alpha.,14.beta.,16.beta.,17z)-

60. 29-nordammara-17(20),24-dien-21-oic Acid, 16-(acetyloxy)-3,11-dihydroxy-, Monosodium Salt, (3alpha,4alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17z)-

61. C76403

62. D00213

63. A865723

64. Q-201142

65. Q27281314

66. Fusidic Acid Sodium Salt, Antibiotic For Culture Media Use Only

67. Sodium 3.alpha.,11.alpha.,16.beta.-trihydroxy-29-nor-8.alpha.,9.beta.,13.alpha.,14.beta.-dammara-17(20),24-dien-21-oate 16-acetate

68. Sodium;(2z)-2-[(3r,4s,5s,8s,9s,10s,11r,13r,14s,16s)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1h-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-en

69. Sodium;(2z)-2-[(3r,4s,5s,8s,9s,10s,11r,13r,14s,16s)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1h-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoate

2.3.3 Other Synonyms

1. Fucidate Sodium

2. Fusidate, Sodium

3. Sodium, Fusidate

4. Fusidic Acid, Sodium Salt

2.4 Create Date

2008-02-05

3 Chemical and Physical Properties

Molecular Formula	C₃₁H₄₇NaO₆
Molecular Weight	538.7 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	538.32703350 g/mol
Monoisotopic Mass	538.32703350 g/mol
Topological Polar Surface Area	107 Å²
Heavy Atom Count	38
Formal Charge	0
Complexity	1000
Isotope Atom Count	0
Defined Atom Stereocenter Count	10
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

Protein Synthesis Inhibitors

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. (See all compounds classified as Protein Synthesis Inhibitors.)