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Chemistry

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Also known as:
Molecular Formula
C19H19N7O6
Molecular Weight
441.4  g/mol
InChI Key
OVBPIULPVIDEAO-LBPRGKRZSA-N

Folic Acid
1 2D Structure

Folic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
2.1.2 InChI
InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
2.1.3 InChI Key
OVBPIULPVIDEAO-LBPRGKRZSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N
2.1.5 Isomeric SMILES
C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N
2.2 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 441.4 g/mol
Molecular Formula C19H19N7O6
XLogP3-1.1
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count9
Rotatable Bond Count9
Exact Mass441.13968135 g/mol
Monoisotopic Mass441.13968135 g/mol
Topological Polar Surface Area209 Ų
Heavy Atom Count32
Formal Charge0
Complexity767
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameFolic acid
PubMed HealthFolic Acid
Drug ClassesNutriceutical, Nutritive Agent
Drug LabelFolic acid, N-[p-[[(2-amino-4-hydroxy-6-pteridiny)methyl]amino]benzoyl]-L-glutamic acid, is a B complex vitamin containing a pteridine moiety linked by a methylene bridge to para-aminobenzoic acid, which is joined by a peptide linkage to glutamic aci...
Active IngredientFolic acid
Dosage FormTablet; Injectable
RouteInjection; Oral
Strength1 mg; 1mg; 5mg/ml
Market StatusPrescription
CompanyBicon Pharm; Excellium; Jubilant Cadista; Cadila Pharms; Invagen Pharms; Hikma Pharms; Watson Labs; Amneal Pharm; Fresenius Kabi Usa; Vintage; Contract Pharmacal

2 of 2  
Drug NameFolic acid
PubMed HealthFolic Acid
Drug ClassesNutriceutical, Nutritive Agent
Drug LabelFolic acid, N-[p-[[(2-amino-4-hydroxy-6-pteridiny)methyl]amino]benzoyl]-L-glutamic acid, is a B complex vitamin containing a pteridine moiety linked by a methylene bridge to para-aminobenzoic acid, which is joined by a peptide linkage to glutamic aci...
Active IngredientFolic acid
Dosage FormTablet; Injectable
RouteInjection; Oral
Strength1 mg; 1mg; 5mg/ml
Market StatusPrescription
CompanyBicon Pharm; Excellium; Jubilant Cadista; Cadila Pharms; Invagen Pharms; Hikma Pharms; Watson Labs; Amneal Pharm; Fresenius Kabi Usa; Vintage; Contract Pharmacal

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117440, , Singapore Singapore","customerAddress":"401 4TH FL WINDSOR HOUSE CST RD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734287400,"product":"FOLIC ACID (NOT FOR MEDICINAL USE) FOLIC ACID (NOT FOR MEDICINAL USE)","address":"AGARWAL B2B CENTRE, 604 KANCHPADA","city":"MUMBAI","supplier":"JIANGXI TIANXIN PHARMACEUTICALS CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SUN RISE ENTERPRISES","customerCountry":"INDIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"21.5","totalValueFC":"32532","currency":"USD","unitRateINR":"1842.8","date":"16-Dec-2024","totalValueINR":"2764212.5","totalValueInUsd":"32532","indian_port":"JNPT","hs_no":"29362910","bill_no":"7275858","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"LEPING INDUSTRIAL ZONE, LEPING JIANGXI CHINA CHINA CN","customerAddress":"AGARWAL B2B CENTRE, 604 KANCHPADA"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734287400,"product":"FOLIC ACID (NOT FOR MEDICINAL USE) FOLIC ACID (NOT FOR MEDICINAL USE)","address":"AGARWAL B2B CENTRE, 604 KANCHPADA","city":"MUMBAI","supplier":"WELFULL GROUP CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SUN RISE ENTERPRISES","customerCountry":"INDIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"22.5","totalValueFC":"34044","currency":"USD","unitRateINR":"1928.5","date":"16-Dec-2024","totalValueINR":"2892687.5","totalValueInUsd":"34044","indian_port":"JNPT","hs_no":"29362910","bill_no":"7276826","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"D TOWER ,OCEAN INTERNATIONAL CENTRE NO 333, YUANJIAN ROAD GONGSHU DISTRICT HANGZHOU ZHEJINAG CN","customerAddress":"AGARWAL B2B CENTRE, 604 KANCHPADA"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1743964200,"product":"FOLIC ACID (NOT FOR MEDICAL USE) FOLIC ACID (NOT FOR MEDICAL USE)","address":"N\/A","city":"","supplier":"ANHUI TIGER VITAMIN INDUSTRIAL CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"AADI GIRI PRIVATE LTD","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"41","totalValueFC":"41516.3","currency":"USD","unitRateINR":"3553.9","date":"07-Apr-2025","totalValueINR":"3553871","totalValueInUsd":"41516.3","indian_port":"JNPT","hs_no":"29362910","bill_no":"9354787","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"WEISI ROAD ECONOMIC DEVLOPMENT ZONE GUZHEN ANHUI CHINA SDNF China","customerAddress":"N\/A"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1747506600,"product":"FOLIC ACID FOOD GRADE -SWITZERLAND FOLIC ACID FOOD GRADE -SWITZERLAND","address":"401 4TH FL WINDSOR HOUSE CST RD","city":"MUMBAI, MAHARASHTRA.","supplier":"DSM NUTRITIONAL PRODUCTS ASIA PACIFIC","supplierCountry":"SWITZERLAND","foreign_port":"ROTTERDAM","customer":"DSM NUTRITIONAL PRODUCTS INDIA PRIVATE LTD","customerCountry":"INDIA","quantity":"75.00","actualQuantity":"75","unit":"KGS","unitRateFc":"34.8","totalValueFC":"2649.3","currency":"USD","unitRateINR":"3009.7","date":"18-May-2025","totalValueINR":"225726","totalValueInUsd":"2649.3","indian_port":"JNPT","hs_no":"29362910","bill_no":"2136718","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"ROTTERDAM","supplierAddress":"30 PASIR PANJANG ROAD #13-31, MAPLE TREE BUSINESS CITY, Singapore - 117 440, , Singapore Singapore","customerAddress":"401 4TH FL WINDSOR HOUSE CST RD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q3","strtotime":1758652200,"product":"FOLIC ACID (NOT FOR MEDICINAL USE) (INV NO. W2508537RC2509017)FOLIC ACID (NOT FOR MEDICINAL USE)","address":"215 SAI CHAMBERS, NEAR BUS DEPOT,S","city":"MUMBAI,MAHARASHTRA","supplier":"ARSHINE FOOD ADDITIVES CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"RAIVAT IMPEX PRIVATE LTD","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"30.1","totalValueFC":"30324.9","currency":"N\/A","unitRateINR":"2676.8","date":"24-Sep-2025","totalValueINR":"2676750.86","totalValueInUsd":"30324.9","indian_port":"JNPT","hs_no":"29362910","bill_no":"4709734","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"BLOCK 14, NO. 100 LUYUN ROAD HI-TECH INDUSTRIAL DEVELOPMENT ZONE CHANGSHA CHINA","customerAddress":"215 SAI CHAMBERS, NEAR BUS DEPOT,S"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1759775400,"product":"FOLIC ACID PH - SWITZERLAND (FOR MEDICINAL USE) FOLIC ACID PH - (FOR MEDICINAL USE)SWITZERLAND","address":"401 4TH FL WINDSOR HOUSE CST RD","city":"MUMBAI, MAHARASHTRA.","supplier":"DSM NUTRITIONAL PRODUCTS ASIA PACIFIC","supplierCountry":"SWITZERLAND","foreign_port":"ROTTERDAM","customer":"DSM NUTRITIONAL PRODUCTS INDIA PRIVATE LTD","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"137","totalValueFC":"278056.8","currency":"N\/A","unitRateINR":"12286","date":"07-Oct-2025","totalValueINR":"24572000","totalValueInUsd":"278056.8","indian_port":"JNPT","hs_no":"29362910","bill_no":"4944966","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"ROTTERDAM","supplierAddress":"30 PASIR PANJANG ROAD #13-31, MAPLE TREE BUSINESS CITY, Singapore - 117 440, , Singapore Singapore","customerAddress":"401 4TH FL WINDSOR HOUSE CST RD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1762885800,"product":"VITAMIN B9: FOLIC ACID (IMPORT UNDER 100% EOU) (LOP ITEM NO:61)VITAMIN B9 FOLIC ACID","address":"Koyikkalethu Veeyapuram","city":"Alappuzha","supplier":"QINGDAO KIMBEREED INTERNATIONAL TRADE COLTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"MOLECULES BIO LABS PRIVATE LTD","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"90.5","totalValueFC":"455.8","currency":"USD","unitRateINR":"8102.9","date":"12-Nov-2025","totalValueINR":"40514.66","totalValueInUsd":"455.8","indian_port":"Cochin Air","hs_no":"29362910","bill_no":"1","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"ROOM 0523, BUILDING 1, SHENLAN APARTMENT,NO.880 TONGAN ROAD, QINGDAO 266061, CHINA CN","customerAddress":"Koyikkalethu Veeyapuram"}]
19-Jan-2022
30-Dec-2025
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DRUG PRODUCT COMPOSITIONS

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DOSAGE - FOR SOLUTION;INTRAVENOUS - 80MG/VIAL...DOSAGE - FOR SOLUTION;INTRAVENOUS - 80MG/VIAL;0.02MG/VIAL;0.001MG/VIAL;5MG/VIAL;0.01MG/VIAL;0.14MG/VIAL;17MG/VIAL;0.2MG/VIAL;1MG/VIAL;1.4MG/VIAL;EQ 1.2MG BASE/VIAL;0.7MG/VIAL;7MG/VIAL

USFDA APPLICATION NUMBER - 18920

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DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/...DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;0.03MG/ML

USFDA APPLICATION NUMBER - 21163

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DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/...DOSAGE - SOLUTION;INTRAVENOUS - 2 IU/ML;40MG/ML;12MCG/ML;40 IU/ML;1MCG/ML;3MG/ML;120MCG/ML;8MG/ML;1.2MG/ML;0.72MG/ML;1.2MG/ML;660 IU/ML;30MCG/ML

USFDA APPLICATION NUMBER - 21163

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DOSAGE - INJECTABLE;INTRAVENOUS - 200MG/VIAL;...DOSAGE - INJECTABLE;INTRAVENOUS - 200MG/VIAL;0.06MG/VIAL;0.005MG/VIAL;15MG/VIAL;0.005MG/VIAL;0.6MG/VIAL;40MG/VIAL;6MG/VIAL;3.6MG/VIAL;6MG/VIAL;1MG/VIAL;10MG/VIAL;0.15MG/VIAL

USFDA APPLICATION NUMBER - 21625

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DOSAGE - INJECTABLE;INJECTION - 20MG/ML;0.006...DOSAGE - INJECTABLE;INJECTION - 20MG/ML;0.006MG/ML;0.05MCG/ML;1.5MG/ML;0.0005MG/ML;0.06MG/ML;4MG/ML;0.6MG/ML;0.36MG/ML;0.6MG/ML;0.1MG/ML;1MG/ML

USFDA APPLICATION NUMBER - 8809

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ABOUT THIS PAGE

Looking for / Folic Acid API manufacturers, exporters & distributors?

Folic Acid manufacturers, exporters & distributors 1

25

PharmaCompass offers a list of Folic Acid API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Folic Acid manufacturer or Folic Acid supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Folic Acid manufacturer or Folic Acid supplier.

PharmaCompass also assists you with knowing the Folic Acid API Price utilized in the formulation of products. Folic Acid API Price is not always fixed or binding as the Folic Acid Price is obtained through a variety of data sources. The Folic Acid Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Folic Acid

Folvron Manufacturers

A Folvron manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Folvron, including repackagers and relabelers. The FDA regulates Folvron manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Folvron API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Folvron manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Folvron Suppliers

A Folvron supplier is an individual or a company that provides Folvron active pharmaceutical ingredient (API) or Folvron finished formulations upon request. The Folvron suppliers may include Folvron API manufacturers, exporters, distributors and traders.

click here to find a list of Folvron suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Folvron USDMF

A Folvron DMF (Drug Master File) is a document detailing the whole manufacturing process of Folvron active pharmaceutical ingredient (API) in detail. Different forms of Folvron DMFs exist exist since differing nations have different regulations, such as Folvron USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Folvron DMF submitted to regulatory agencies in the US is known as a USDMF. Folvron USDMF includes data on Folvron's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Folvron USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Folvron suppliers with USDMF on PharmaCompass.

Folvron JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Folvron Drug Master File in Japan (Folvron JDMF) empowers Folvron API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Folvron JDMF during the approval evaluation for pharmaceutical products. At the time of Folvron JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Folvron suppliers with JDMF on PharmaCompass.

Folvron CEP

A Folvron CEP of the European Pharmacopoeia monograph is often referred to as a Folvron Certificate of Suitability (COS). The purpose of a Folvron CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Folvron EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Folvron to their clients by showing that a Folvron CEP has been issued for it. The manufacturer submits a Folvron CEP (COS) as part of the market authorization procedure, and it takes on the role of a Folvron CEP holder for the record. Additionally, the data presented in the Folvron CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Folvron DMF.

A Folvron CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Folvron CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Folvron suppliers with CEP (COS) on PharmaCompass.

Folvron WC

A Folvron written confirmation (Folvron WC) is an official document issued by a regulatory agency to a Folvron manufacturer, verifying that the manufacturing facility of a Folvron active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Folvron APIs or Folvron finished pharmaceutical products to another nation, regulatory agencies frequently require a Folvron WC (written confirmation) as part of the regulatory process.

click here to find a list of Folvron suppliers with Written Confirmation (WC) on PharmaCompass.

Folvron NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Folvron as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Folvron API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Folvron as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Folvron and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Folvron NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Folvron suppliers with NDC on PharmaCompass.

Folvron GMP

Folvron Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Folvron GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Folvron GMP manufacturer or Folvron GMP API supplier for your needs.

Folvron CoA

A Folvron CoA (Certificate of Analysis) is a formal document that attests to Folvron's compliance with Folvron specifications and serves as a tool for batch-level quality control.

Folvron CoA mostly includes findings from lab analyses of a specific batch. For each Folvron CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Folvron may be tested according to a variety of international standards, such as European Pharmacopoeia (Folvron EP), Folvron JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Folvron USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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