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Chemistry

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Also known as: 29205-06-9, Fluocortolone 21-pivalate, Einecs 249-504-4, Unii-9j8al6k50q, 9j8al6k50q, [2-[(6s,8s,9s,10r,11s,13s,14s,16r,17s)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate
Molecular Formula
C27H37FO5
Molecular Weight
460.6  g/mol
InChI Key
XZBJVIQXJHGUBE-HZMVJJPJSA-N
FDA UNII
9J8AL6K50Q

Fluocortolone Pivalate
A glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
1 2D Structure

Fluocortolone Pivalate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[2-[(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate
2.1.2 InChI
InChI=1S/C27H37FO5/c1-14-9-17-16-11-19(28)18-10-15(29)7-8-26(18,5)23(16)20(30)12-27(17,6)22(14)21(31)13-33-24(32)25(2,3)4/h7-8,10,14,16-17,19-20,22-23,30H,9,11-13H2,1-6H3/t14-,16+,17+,19+,20+,22-,23-,26+,27+/m1/s1
2.1.3 InChI Key
XZBJVIQXJHGUBE-HZMVJJPJSA-N
2.1.4 Canonical SMILES
CC1CC2C3CC(C4=CC(=O)C=CC4(C3C(CC2(C1C(=O)COC(=O)C(C)(C)C)C)O)C)F
2.1.5 Isomeric SMILES
C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@H]1C(=O)COC(=O)C(C)(C)C)C)O)C)F
2.2 Other Identifiers
2.2.1 UNII
9J8AL6K50Q
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Caproate, Fluocortolone

2. Fluocortolone

3. Fluocortolone Caproate

4. Pivalate, Fluocortolone

5. Ultralan

2.3.2 Depositor-Supplied Synonyms

1. 29205-06-9

2. Fluocortolone 21-pivalate

3. Einecs 249-504-4

4. Unii-9j8al6k50q

5. 9j8al6k50q

6. [2-[(6s,8s,9s,10r,11s,13s,14s,16r,17s)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate

7. 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate

8. Ultradil (tn)

9. Fluocortolone Trimethylacetate

10. Schembl5675315

11. Dtxsid30951798

12. Chebi:177427

13. Fluocortolone Pivalate Assay Standard

14. Fluocortolone Pivalate [mart.]

15. Fluocortolone Pivalate [who-dd]

16. Fluocortolone Pivalate [ep Monograph]

17. Fluocortolone Pivalate For Id And Assay Crs

18. D07973

19. Q27272623

20. 6-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl 2,2-dimethylpropanoate

21. [2-[(6s,8s,9s,10r,11s,13s,14s,16r,17s)-6-luoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate

22. 6.alpha.-fluoro-11.beta.-hydroxy-16.alpha.-methyl-3,20-dioxopregna-1,4-dien-21-yl 2,2-dimethylpropanoate

2.3.3 Other Synonyms

1. Pivalate, Fluocortolone

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 460.6 g/mol
Molecular Formula C27H37FO5
XLogP34.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area80.7
Heavy Atom Count33
Formal Charge0
Complexity929
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Glucocorticoids

A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system. (See all compounds classified as Glucocorticoids.)


Anti-Inflammatory Agents

Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)


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ABOUT THIS PAGE

Looking for 29205-06-9 / Fluocortolone Pivalate API manufacturers, exporters & distributors?

Fluocortolone Pivalate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Fluocortolone Pivalate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Fluocortolone Pivalate manufacturer or Fluocortolone Pivalate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Fluocortolone Pivalate manufacturer or Fluocortolone Pivalate supplier.

API | Excipient name

Fluocortolone Pivalate

Synonyms

29205-06-9, Fluocortolone 21-pivalate, Einecs 249-504-4, Unii-9j8al6k50q, 9j8al6k50q, [2-[(6s,8s,9s,10r,11s,13s,14s,16r,17s)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate

Cas Number

29205-06-9

Unique Ingredient Identifier (UNII)

9J8AL6K50Q

About Fluocortolone Pivalate

A glucocorticoid with anti-inflammatory activity used topically for various skin disorders.

Fluocortolone pivalate Assay Standard Manufacturers

A Fluocortolone pivalate Assay Standard manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Fluocortolone pivalate Assay Standard, including repackagers and relabelers. The FDA regulates Fluocortolone pivalate Assay Standard manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Fluocortolone pivalate Assay Standard API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Fluocortolone pivalate Assay Standard manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

Fluocortolone pivalate Assay Standard Suppliers

A Fluocortolone pivalate Assay Standard supplier is an individual or a company that provides Fluocortolone pivalate Assay Standard active pharmaceutical ingredient (API) or Fluocortolone pivalate Assay Standard finished formulations upon request. The Fluocortolone pivalate Assay Standard suppliers may include Fluocortolone pivalate Assay Standard API manufacturers, exporters, distributors and traders.

click here to find a list of Fluocortolone pivalate Assay Standard suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

Fluocortolone pivalate Assay Standard GMP

Fluocortolone pivalate Assay Standard Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Fluocortolone pivalate Assay Standard GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Fluocortolone pivalate Assay Standard GMP manufacturer or Fluocortolone pivalate Assay Standard GMP API supplier for your needs.

Fluocortolone pivalate Assay Standard CoA

A Fluocortolone pivalate Assay Standard CoA (Certificate of Analysis) is a formal document that attests to Fluocortolone pivalate Assay Standard's compliance with Fluocortolone pivalate Assay Standard specifications and serves as a tool for batch-level quality control.

Fluocortolone pivalate Assay Standard CoA mostly includes findings from lab analyses of a specific batch. For each Fluocortolone pivalate Assay Standard CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Fluocortolone pivalate Assay Standard may be tested according to a variety of international standards, such as European Pharmacopoeia (Fluocortolone pivalate Assay Standard EP), Fluocortolone pivalate Assay Standard JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Fluocortolone pivalate Assay Standard USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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