Find Flunixin Meglumine manufacturers, exporters & distributors on PharmaCompass

Flunixin Meglumine

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

13 API Suppliers, 1 USDMF, 7 CEP/COS, 8 NDC API, 7 Listed Suppliers

PRICE INFORMATION

API Reference Price, API Exports, API Imports

INTERMEDIATES

1 Suppliers

1 Suppliers

DOSSIERs // Finished Dosage Formulations

8 Dossiers, 6 Canada, 2 Listed Dossiers

RELATED EXCIPIENT COMPANIES

Suppliers, 11 BASF, 6 Roquette, 5 Actylis, 3 SPI Pharma, 2 Nanjing Well Pharmaceutical, 2 Finar, 2 Gangwal Healthcare, 2 Ingredion Pharma Solutions, 2 Seqens, 2 Nomisma Healthcare, 1 Kerry, 1 Seppic, 1 Gangwal Chemicals, 1 Shanghai Welltone Material Technology Co., Ltd, 1 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Boai NKY Pharmaceuticals Ltd

EXCIPIENTS BY APPLICATIONS

12 Fillers, Diluents & Binders, 11 Topical, 7 Parenteral, 7 Solubilizers, 7 Controlled & Modified Release, 6 Thickeners and Stabilizers, 5 Direct Compression, 4 Film Formers & Plasticizers, 3 Co-Processed Excipients, 3 Chewable & Orodispersible Aids, 3 Taste Masking, 3 Disintegrants & Superdisintegrants, 2 Coating Systems & Additives, 2 Granulation

MARKET PLACE

8 APIs

8 APIs

ANALYTICAL SOLUTION(s)

3 EDQM Standards, 1 USP Standards, 1 Other Ref. Standards

DIGITAL CONTENT

1 News

1 News

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

167

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 42461-84-7, Flunixin meglumin, Banamine, Sch 14714 meglumine, Flumeglumine, Flunixin-s

Molecular Formula

C₂₁H₂₈F₃N₃O₇

Molecular Weight

491.5 g/mol

InChI Key

MGCCHNLNRBULBU-WZTVWXICSA-N

FDA UNII

8Y3JK0JW3U

1 2D Structure

Flunixin Meglumine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol;2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid

2.1.2 InChI

InChI=1S/C14H11F3N2O2.C7H17NO5/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-7H,1H3,(H,18,19)(H,20,21);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1

2.1.3 InChI Key

MGCCHNLNRBULBU-WZTVWXICSA-N

2.1.4 Canonical SMILES

CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F.CNCC(C(C(C(CO)O)O)O)O

2.1.5 Isomeric SMILES

CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O

2.2 Other Identifiers

2.2.1 UNII

8Y3JK0JW3U

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Banamine

2. Finadyne

3. Sch 14714 Meglumine

2.3.2 Depositor-Supplied Synonyms

1. 42461-84-7

2. Flunixin Meglumin

3. Banamine

4. Sch 14714 Meglumine

5. Flumeglumine

6. Flunixin-s

7. Flunixin N-methylglucanine

8. Flunixin (meglumine)

9. Flunixin Meglumine Salt

10. Sch-14714 Meglumine

11. Nsc-759583

12. 8y3jk0jw3u

13. Finadyne

14. Chebi:76144

15. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)nicotinate

16. 1-deoxy-1-(methylamino)-d-glucitol 2-(2-methyl-3-(perfluoromethyl)anilino)nicotinate

17. 3-pyridinecarboxylic Acid, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-, Compd. With 1-deoxy-1-(methylamino)-d-glucitol (1:1)

18. Banamine (veterinary)

19. Flunixin Meglumine [usan]

20. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentol;2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic Acid

21. Smr000875279

22. Sr-05000001901

23. Einecs 255-836-0

24. Unii-8y3jk0jw3u

25. Flunixin Meglumine [usan:usp]

26. Flunixin Meglumine (usp)

27. Banamine [vetarynary] (tn)

28. Schembl43691

29. Bspbio_002558

30. 2-(alpha(sup 3),alpha(sup 3),alpha(sup 3)-trifluoro-2,3-xylidino)nicotinic Acid Compound With 1-deoxy-1-(methylamino)-d-glucitol (1:1)

31. Mls001333159

32. Mls002153985

33. Spectrum1505113

34. Chembl1733447

35. Hms2093i10

36. Hms2234k05

37. Hms3884j07

38. Pharmakon1600-01505113

39. Flunixin Meglumine [mart.]

40. Flunixin Meglumine [usp-rs]

41. Hy-b0386

42. Flunixin Meglumine Salt [mi]

43. Mfcd01725419

44. Nsc759583

45. S2108

46. Flunixin Meglumine, >=98% (hplc)

47. Akos015895954

48. Ac-6012

49. Ccg-213338

50. Flunixin Meglumine [green Book]

51. Ks-5126

52. Nsc 759583

53. Ncgc00180889-01

54. 2-((2-methyl-3-(trifluoromethyl)-phenyl)amino)-3-pyridinecarboxylic Acid With Meglumine Compounded

55. D-glucitol, 1-deoxy-1-(methylamino)-, 2-((2-methyl-3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxylate (salt)

56. Flunixin Meglumine [usp Monograph]

57. Sw196448-3

58. Flunixin Meglumine 100 Microg/ml In Methanol

59. D04216

60. H10204

61. Ab00920714_05

62. Ab00920714_06

63. 461f847

64. Flunixin Meglumine 100 Microg/ml In Acetonitrile

65. Q-201124

66. Sr-05000001901-1

67. Sr-05000001901-3

68. Q27145782

69. Flunixin Meglumine, European Pharmacopoeia (ep) Reference Standard

70. Flunixin Meglumine, United States Pharmacopeia (usp) Reference Standard

71. Flunixin Meglumine, Pharmaceutical Secondary Standard; Certified Reference Material

72. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol 2-(2-methyl-3-(trifluoromethyl)phenylamino)nicotinate

73. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol2-((2-methyl-3-(trifluoromethyl)phenyl)amino)nicotinate

74. 1-deoxy-1-(methylazaniumyl)-d-glucitol 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinate

75. 2-(.alpha.(sup 3),.alpha.(sup 3),.alpha.(sup 3)-trifluoro-2,3-xylidino)nicotinic Acid Compound With 1-deoxy-1-(methylamino)-d-glucitol (1:1)

76. 2-{[2-methyl-3-(trifluoromethyl)phenyl]amino}nicotinic Acid--1-deoxy-1-(methylamino)-d-glucitol (1/1)

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₈F₃N₃O₇
Molecular Weight	491.5 g/mol
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	13
Rotatable Bond Count	9
Exact Mass	491.18793473 g/mol
Monoisotopic Mass	491.18793473 g/mol
Topological Polar Surface Area	175 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	510
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)

Antipyretics

Drugs that are used to reduce body temperature in fever. (See all compounds classified as Antipyretics.)