Synopsis
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DRUG PRODUCT COMPOSITIONS0
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1. Apo Fluconazole
2. Apo-fluconazole
3. Bagyne
4. Diflucan
5. Fluc Hexal
6. Flucobeta
7. Flucolich
8. Fluconazol Abz
9. Fluconazol Al
10. Fluconazol Isis
11. Fluconazol Ratiopharm
12. Fluconazol Stada
13. Fluconazol Von Ct
14. Fluconazol-isis
15. Fluconazol-ratiopharm
16. Flunazul
17. Fungata
18. Lavisa
19. Loitin
20. Neofomiral
21. Oxifungol
22. Solacap
23. Triflucan
24. Uk 49858
25. Uk-49858
26. Uk49858
27. Zonal
1. 86386-73-4
2. Diflucan
3. Triflucan
4. Biozolene
5. Elazor
6. Biocanol
7. Fluconazol
8. Fungata
9. Zoltec
10. Fluconazolum
11. Flucostat
12. Difluconazole
13. 2-(2,4-difluorophenyl)-1,3-di(1h-1,2,4-triazol-1-yl)propan-2-ol
14. 2-(2,4-difluorophenyl)-1,3-bis(1h-1,2,4-triazol-1-yl)propan-2-ol
15. Uk 49858
16. Uk-49858
17. 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol
18. Alkanazole
19. Flucazol
20. Fluconazole [usan]
21. 123631-92-5
22. Pritenzol
23. Flukezol
24. Flunizol
25. Zonal
26. Chembl106
27. Nsc-758661
28. 2-(2,4-difluorophenyl)-1,3-bis(1h-1,2,4-triazol-1-yl)-2-propanol
29. 8vzv102jfy
30. 2,4-difluoro-alpha,alpha-bis(1h-1,2,4-triazol-1-ylmethyl)benzyl Alcohol
31. 1h-1,2,4-triazole-1-ethanol, Alpha-(2,4-difluorophenyl)-alpha-(1h-1,2,4-triazol-1-ylmethyl)-
32. Uk-49,858
33. Alflucoz
34. Cryptal
35. Dimycon
36. Oxifugol
37. Canzol
38. Chebi:46081
39. Forcan
40. Syscan
41. Baten
42. Mutum
43. Zemyc
44. 2-(2,4-difluorophenyl)-1,3-di-1h-1,2,4-triazol-1-ylpropan-2-ol
45. Bayt006267
46. Bayt-006267
47. Alpha-(2,4-difluorophenyl)-alpha-(1h-1,2,4-triazol-1-ylmethyl)-1h-1,2,4-triazole-1-ethanol
48. Ncgc00095089-01
49. Flunazol
50. Fluconazol [spanish]
51. Fluconazolum [latin]
52. Loitin
53. Dsstox_cid_627
54. 2-(2,4-difluoro-phenyl)-1,3-bis-[1,2,4]triazol-1-yl-propan-2-ol
55. Dsstox_rid_75701
56. Dsstox_gsid_20627
57. Flc
58. Drg-0005
59. Diflazon
60. Fuconal
61. Triconal
62. Trican
63. 2-(2,4-difluorfenyl)-1,3-bis(1h-1,2,4-triazool-1-yl)propaan-2-ol
64. Diflucan (tn)
65. Smr000471882
66. Cas-86386-73-4
67. Flcz
68. Ccris 7211
69. Fluconazole & Hgcsf
70. Diflucan In Sodium Chloride 0.9%
71. Hsdb 7420
72. Sr-01000765440
73. Fluconazole In Sodium Chloride 0.9%
74. Unii-8vzv102jfy
75. Diflucan In Dextrose 5% In Plastic Container
76. Fluconazoli
77. Flucoral
78. Fluconazole & Mc-510,011
79. Fluconazole (f)
80. Fluconazole,(s)
81. 2,4-difluoro-,1-bis(1h-1,2,4-triazol-1-ylmethyl)benzyl Alcohol
82. Fluconazole In Dextrose 5% In Plastic Container
83. 2,4-difluoro-alpha,alpha-1-bis(1h-1,2,4-triazol-1-ylmethyl)benzyl Alcohol
84. Fluconazole- Bio-x
85. Fluzon [antifungal]
86. Mfcd00274549
87. Ks-1059
88. Fluconazole [usan:usp:inn:ban:jan]
89. Fluconazole In Sodium Chloride 0.9% In Plastic Container
90. Fluconazole In Combination With Mgcd290
91. Spectrum_001654
92. Diflucan In Sodium Chloride 0.9% In Plastic Container
93. Fluconazole [mi]
94. Spectrum2_001607
95. Spectrum3_001912
96. Spectrum4_000090
97. Spectrum5_001277
98. Fluconazole [inn]
99. Fluconazole [jan]
100. F0677
101. Fluconazole [hsdb]
102. Mgcd290 And Fluconazole
103. Fluconazole [vandf]
104. Cid_3365
105. Mg-3290 And Fluconazole
106. Schembl3151
107. Fluconazole [mart.]
108. Bspbio_003504
109. Fluconazole [usp-rs]
110. Fluconazole [who-dd]
111. Fluconazole [who-ip]
112. Kbiogr_000360
113. Kbioss_002134
114. Mls001066394
115. Mls001165780
116. Mls001195645
117. Mls001304713
118. Mls001306492
119. Mls006011884
120. Bidd:gt0799
121. Divk1c_001030
122. Spectrum1503975
123. Spbio_001613
124. Zinc4009
125. Fluconazole (jp17/usp/inn)
126. Dtxsid3020627
127. Bdbm25817
128. Hms503m21
129. Kbio1_001030
130. Kbio2_002134
131. Kbio2_004702
132. Kbio2_007270
133. Kbio3_003009
134. Fluconazole [orange Book]
135. Ninds_001030
136. Fluconazole [ep Monograph]
137. Hms1922o10
138. Hms2090i20
139. Hms2093m21
140. Hms2230o22
141. Hms3259h13
142. Hms3373i19
143. Hms3654p15
144. Hms3715f21
145. Hms3748g19
146. Pharmakon1600-01503975
147. Fluconazole [usp Monograph]
148. Fluconazoli [who-ip Latin]
149. Amy23415
150. Bcp28522
151. Fluconazole 2.0 Mg/ml In Methanol
152. Hy-b0101
153. 1,2,4-triazol-1-yl)propan-2-ol
154. Tox21_111419
155. Tox21_202240
156. Tox21_300581
157. Ac-428
158. Bbl005614
159. Ccg-39065
160. Dl-407
161. Fluconazole & Human Recombinant Granulocyte Colony Stimulating Factor
162. Nsc754343
163. Nsc758661
164. S1331
165. Stk619301
166. Akos000280854
167. Tox21_111419_1
168. Cs-1835
169. Db00196
170. Fluconazole 100 Microg/ml In Methanol
171. Fluconazole, >=98% (hplc), Powder
172. Nc00650
173. Nsc 758661
174. Nsc-754343
175. Idi1_001030
176. Ncgc00095089-02
177. Ncgc00095089-04
178. Ncgc00095089-05
179. Ncgc00095089-06
180. Ncgc00095089-07
181. Ncgc00095089-08
182. Ncgc00095089-09
183. Ncgc00095089-10
184. Ncgc00095089-11
185. Ncgc00254412-01
186. Ncgc00259789-01
187. 2-(2,4-difluorophenyl)-1,3-di(1h-
188. Bf164466
189. Fluconazole 100 Microg/ml In Acetonitrile
190. Sbi-0051880.p002
191. Uk-049858
192. Ft-0626437
193. Sw199616-2
194. En300-53634
195. C07002
196. D00322
197. Ab00052399-07
198. Ab00052399-08
199. Ab00052399_09
200. Ab00052399_10
201. 386f734
202. A841625
203. Q411478
204. Q-201120
205. Sr-01000765440-2
206. Sr-01000765440-4
207. Sr-01000765440-8
208. Uk-49858;uk 49858;uk49858
209. Brd-k05977355-001-02-6
210. Brd-k05977355-001-09-1
211. F2173-0496
212. Z235354561
213. Fluconazole, European Pharmacopoeia (ep) Reference Standard
214. 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)-2-propanol
215. Fluconazole, United States Pharmacopeia (usp) Reference Standard
216. 2-[2,4-bis(fluoranyl)phenyl]-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol
217. Fluconazole, Pharmaceutical Secondary Standard; Certified Reference Material
218. 2,4-difluoro-1',1'-bis(1h-1,2,4-triazol-1-ylmethyl)benzyl Alcohol
219. A-(2,4-difluorophenyl)-a-(1h-1,2,4-triazol-1- Ylmethyl)-1h-1,2,4-triazole-1-ethanol
220. Fluconazole For Peak Identification, European Pharmacopoeia (ep) Reference Standard
221. Fluconazole Solution, 2.0 Mg/ml In Methanol, Ampule Of 1 Ml, Certified Reference Material
222. .alpha.-(2,4-difluorophenyl)-.alpha.-(1h-1,2,4-triazol-1-ylmethyl)-1h-1,2,4-triazole-1-ethanol
223. 1h-1,2,4-triazole-1-ethanol, .alpha.-(2,4-difluorophenyl)-.alpha.-(1h-1,2,4-triazol-1-ylmethyl)-
224. 1h-1,2,4-triazole-1-ethanol, 1-(2,4-difluorophenyl)-1-(1h-1,2,4-triazol-1-ylmethyl)-
| Molecular Weight | 306.27 g/mol |
|---|---|
| Molecular Formula | C13H12F2N6O |
| XLogP3 | 0.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 5 |
| Exact Mass | 306.10406535 g/mol |
| Monoisotopic Mass | 306.10406535 g/mol |
| Topological Polar Surface Area | 81.6 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 358 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
| 1 of 4 | |
|---|---|
| Drug Name | Diflucan |
| PubMed Health | Fluconazole |
| Drug Classes | Antifungal |
| Drug Label | DIFLUCAN (fluconazole), the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration, as a powder for oral suspension, and as a sterile solution for intravenous use in glass and in Viaflex P... |
| Active Ingredient | Fluconazole |
| Dosage Form | Tablet; For suspension |
| Route | Oral |
| Strength | 200mg/5ml; 200mg; 100mg; 50mg; 150mg; 50mg/5ml |
| Market Status | Prescription |
| Company | Pfizer |
| 2 of 4 | |
|---|---|
| Drug Name | Fluconazole |
| PubMed Health | Fluconazole |
| Drug Classes | Antifungal |
| Drug Label | Fluconazole USP, the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration. Fluconazole USP is designated chemically as 2,4-difluoro-,1-bis(1H-1,2,4-triazol-1-ylmethyl) benzyl alcohol wit... |
| Active Ingredient | Fluconazole |
| Dosage Form | Tablet; For suspension |
| Route | Oral |
| Strength | 200mg/5ml; 200mg; 150mg; 50mg/5ml; 100mg; 50mg |
| Market Status | Prescription |
| Company | Ranbaxy; Teva; Apotex; Aurobindo Pharma; Taro; Unique Pharm Labs; Roxane; Glenmark Generics; Ivax Sub Teva Pharms; Aurobindo Pharm; Dr Reddys Labs; Mylan |
| 3 of 4 | |
|---|---|
| Drug Name | Diflucan |
| PubMed Health | Fluconazole |
| Drug Classes | Antifungal |
| Drug Label | DIFLUCAN (fluconazole), the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration, as a powder for oral suspension, and as a sterile solution for intravenous use in glass and in Viaflex P... |
| Active Ingredient | Fluconazole |
| Dosage Form | Tablet; For suspension |
| Route | Oral |
| Strength | 200mg/5ml; 200mg; 100mg; 50mg; 150mg; 50mg/5ml |
| Market Status | Prescription |
| Company | Pfizer |
| 4 of 4 | |
|---|---|
| Drug Name | Fluconazole |
| PubMed Health | Fluconazole |
| Drug Classes | Antifungal |
| Drug Label | Fluconazole USP, the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration. Fluconazole USP is designated chemically as 2,4-difluoro-,1-bis(1H-1,2,4-triazol-1-ylmethyl) benzyl alcohol wit... |
| Active Ingredient | Fluconazole |
| Dosage Form | Tablet; For suspension |
| Route | Oral |
| Strength | 200mg/5ml; 200mg; 150mg; 50mg/5ml; 100mg; 50mg |
| Market Status | Prescription |
| Company | Ranbaxy; Teva; Apotex; Aurobindo Pharma; Taro; Unique Pharm Labs; Roxane; Glenmark Generics; Ivax Sub Teva Pharms; Aurobindo Pharm; Dr Reddys Labs; Mylan |
Mesh Heading: Antifungal agents
National Library of Medicine, SIS; ChemIDplus Record for Fluconazole (86386-73-4). Available from, as of April 17, 2006: https://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
MEDICATION: Antifungal; Orally active bistriazole antifungal agent
O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 728-9
MEDICATION (VET): Used to treat systemic mycoses, particularly CNS-related conditions in dogs.
Milne, G.W.A. Veterinary Drugs: Synonyms and Properties. Ashgate Publishing Limited, Aldershot, Hampshire, England 2002., p. 80
Fluconazole ... /is/ indicated for the prophylaxis of febrile neutropenia in patients with hematologic malignancies. /NOT included in US product labeling/
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006., p. 335
For more Therapeutic Uses (Complete) data for FLUCONAZOLE (16 total), please visit the HSDB record page.
Although serious adverse hepatic effects have been reported only rarely with fluconazole, the possibility that these effects may occur during fluconazole therapy should be considered. Fluconazole therapy should be discontinued if signs and symptoms consistent with liver disease develop. If abnormal liver function test results occur during fluconazole therapy, the patient should be monitored for the development of more severe hepatic injury.
McEvoy, G.K. (ed.). American Hospital Formulary Service. AHFS Drug Information. American Society of Health-System Pharmacists, Bethesda, MD. 2006., p. 507
Serious hepatic reactions (eg, necrosis, clinical hepatitis, cholestasis, fulminant hepatic failure) have been reported rarely in patients receiving fluconazole therapy. The manufacturer states that a clear relationship between these hepatic effects and daily dosage, duration of therapy, gender, or age has not been demonstrated. While hepatotoxicity usually has been reversible, fatalities have been reported. Fatalities principally have occurred in patients with serious underlying disease (eg, AIDS, malignancy) who were receiving fluconazole concomitantly with other drugs; however, at least one fatality involved an immunocompetent geriatric individual with renal impairment who developed fulminant hepatic necrosis within 10 days after fluconazole therapy was initiated.
McEvoy, G.K. (ed.). American Hospital Formulary Service. AHFS Drug Information. American Society of Health-System Pharmacists, Bethesda, MD. 2006., p. 507
Mild, transient increases (1.5-3 times the upper limit of normal) in serum concentrations of AST (SGOT), ALT (SGPT), alkaline phosphatase, gamma-glutamyltransferase (GGT, gamma-glutamyl transpeptidase, GGTP), and bilirubin have been reported in about 5-7% of patients receiving fluconazole. In most reported cases, concentrations returned to pretreatment levels either during or after fluconazole therapy and were not associated with hepatotoxicity. However, higher increases in serum transaminase concentrations (8 or more times the upper limit of normal), which required discontinuance of the drug, ha
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