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1. Ferinject
2. Injectafer
3. Iron Carboxymaltose
4. Iron Dextri-maltose
5. Polynuclear Iron (iii)-hydroxide 4(r)-(poly-(1->4)-o-alpha-d-glucopyranosyl)-oxy-2(r),3(s),5(r), 6-tetrahydroxy-hexanoate
6. Vit 45
7. Vit-45
1. 9007-72-1
2. Ex-a3450
3. (2s,3s,4s,5r)-4-[(2r,3r,4r,5s,6r)-5-[(2r,3r,4r,5s,6r)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,5,6-tetrahydroxyhexanoate;iron(3+);oxygen(2-);hydroxide;hydrate
Molecular Weight | 788.4 g/mol |
---|---|
Molecular Formula | C24H44FeO25- |
Hydrogen Bond Donor Count | 16 |
Hydrogen Bond Acceptor Count | 25 |
Rotatable Bond Count | 13 |
Exact Mass | 788.152102 g/mol |
Monoisotopic Mass | 788.152102 g/mol |
Topological Polar Surface Area | 382 Ų |
Heavy Atom Count | 50 |
Formal Charge | -1 |
Complexity | 940 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 19 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 5 |
1 of 2 | |
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Drug Name | Injectafer |
PubMed Health | ferric carboxymaltose |
Drug Classes | Iron Supplement |
Drug Label | Ferric carboxymaltose, an iron replacement product, is an iron carbohydrate complex with the chemical name of polynuclear iron (III) hydroxide 4(R)-(poly-(14)-O--D-glucopyranosyl)-oxy-2(R),3(S),5(R),6-tetrahydroxy-hexanoate. It has a relative mo... |
Active Ingredient | Ferric carboxymaltose |
Dosage Form | Injectable |
Route | Intravenous |
Strength | 750mg iron/15ml (50mg iron/ml) |
Market Status | Prescription |
Company | Luitpold |
Patent | 7612109; 7754702 |
2 of 2 | |
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Drug Name | Injectafer |
PubMed Health | ferric carboxymaltose |
Drug Classes | Iron Supplement |
Drug Label | Ferric carboxymaltose, an iron replacement product, is an iron carbohydrate complex with the chemical name of polynuclear iron (III) hydroxide 4(R)-(poly-(14)-O--D-glucopyranosyl)-oxy-2(R),3(S),5(R),6-tetrahydroxy-hexanoate. It has a relative mo... |
Active Ingredient | Ferric carboxymaltose |
Dosage Form | Injectable |
Route | Intravenous |
Strength | 750mg iron/15ml (50mg iron/ml) |
Market Status | Prescription |
Company | Luitpold |
Patent | 7612109; 7754702 |
Ferric carboxymaltose is a iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron or those who have non-dialysis dependent chronic kidney disease.
FDA Label
When measured using positron emission tomography (PET), the red cell uptake of 59-Fe and 52-Fe from INJECTAFER ranged from 61% to 99%. In patients with iron deficiency, the red cell uptake ranged from 91% to 99%. In patients with renal anemia, the red cell uptake ranged from 61% to 84%.
Absorption
When a single dose of 100 to 1000 mg of iron was given to iron deficient patients, the maximum serum concentration (Cmax) was 37 g/mL to 333 g/mL. These levels were obtained 15 minutes to 1.21 hours post dose (Tmax).
Route of Elimination
Renal elimination of iron was negligible.
Volume of Distribution
3 L
7 to 12 hours.
Ferric carboxymaltose is a colloidal iron (III) hydroxide in complex with carboxymaltose, a carbohydrate polymer that release iron.
Interquim comes from an international group of 50 companies active in the pharma, hospital, diagnostics, fine chemicals & feed sectors.
NDC Package Code : 64552-4070
Start Marketing Date : 2013-07-25
End Marketing Date : 2024-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT
DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.
NDC Package Code : 71796-054
Start Marketing Date : 2023-03-29
End Marketing Date : 2024-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT
NDC Package Code : 42973-330
Start Marketing Date : 2020-12-06
End Marketing Date : 2025-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT
NDC Package Code : 59353-363
Start Marketing Date : 2010-04-01
End Marketing Date : 2024-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT
NDC Package Code : 14593-923
Start Marketing Date : 2021-07-21
End Marketing Date : 2024-12-31
Dosage Form (Strength) : POWDER (50kg/50kg)
Marketing Category : BULK INGREDIENT
NDC Package Code : 69766-093
Start Marketing Date : 2023-03-24
End Marketing Date : 2024-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT
NDC Package Code : 68022-7070
Start Marketing Date : 2023-12-25
End Marketing Date : 2025-12-31
Dosage Form (Strength) : POWDER (1kg/kg)
Marketing Category : BULK INGREDIENT FOR HUMAN P...
API Imports and Exports
Importing Country | Total Quantity (KGS) |
Average Price (USD/KGS) |
Number of Transactions |
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Regulatory Info :
Registration Country : Italy
Brand Name : Ferinject
Dosage Form : Ferric Carbossimaltosio 50Mg/Ml 10Ml 1 Units Parenteral Use
Dosage Strength : 1 vial EV 10 ml 50 mg/ml
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy
Regulatory Info :
Registration Country : Italy
Brand Name : Ferinject
Dosage Form : Ferric Carbossimaltosio 50Mg/Ml 2Ml 5 Units Parenteral Use
Dosage Strength : 5 VIALS EV 2 ml 50 mg/ml
Packaging :
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy
Regulatory Info : Originator
Registration Country : South Africa
Brand Name : Ferinject
Dosage Form : INJ
Dosage Strength : 50mg/ml
Packaging : 10X1mg/ml
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
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