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Fencarol

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Also known as: 10447-38-8, Phencarol, Diphenyl(quinuclidin-3-yl)methanol hydrochloride, 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol hydrochloride, Fenkarol, Fencarol

Molecular Formula

C₂₀H₂₄ClNO

Molecular Weight

329.9 g/mol

InChI Key

MVCBFPDJWSQMNY-UHFFFAOYSA-N

FDA UNII

6WSK4828LL

1 2D Structure

Fencarol

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol;hydrochloride

2.1.2 InChI

InChI=1S/C20H23NO.ClH/c22-20(17-7-3-1-4-8-17,18-9-5-2-6-10-18)19-15-21-13-11-16(19)12-14-21;/h1-10,16,19,22H,11-15H2;1H

2.1.3 InChI Key

MVCBFPDJWSQMNY-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1CN2CCC1C(C2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O.Cl

2.2 Other Identifiers

2.2.1 UNII

6WSK4828LL

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Fenatin

2. Fencarol

3. Phencarol

4. Quifenadine

5. Quifenadine Hydrobromide, (+-)-isomer

6. Quinuclidinyl-3-diphenylcarbinol

2.3.2 Depositor-Supplied Synonyms

1. 10447-38-8

2. Phencarol

3. Diphenyl(quinuclidin-3-yl)methanol Hydrochloride

4. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride

5. Fenkarol

6. Fencarol

7. 6wsk4828ll

8. 1-azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol;hydrochloride

9. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride;1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride

10. Alpha,alpha-diphenyl-3-quinuclidinemethanol Hydrochloride;alpha,alpha-diphenyl-3-quinuclidinemethanol Hydrochloride

11. Unii-6wsk4828ll

12. Alpha,alpha-diphenyl-3-quinuclidinemethanol, Hydrochloride

13. 3-quinuclidinemethanol, Alpha,alpha-diphenyl-, Hydrochloride

14. 1-azabicyclo(2.2.2)octane-3-methanol, Alpha,alpha-diphenyl-, Hydrochloride

15. Mls000765321

16. Chembl1510616

17. Schembl11613936

18. Dtxsid30908989

19. Akos005111025

20. Akos030507569

21. Am84319

22. Quifenadine Hydrochloride [who-dd]

23. Smr000289426

24. Ft-0682664

25. Diphenyl(quinuclidin-3-yl)methanolhydrochloride

26. (quinuclidin-3-yl)diphenylcarbinol Hydrochloride

27. A927551

28. Sr-01000323054

29. Sr-01000323054-1

30. (3-quinuclidinyl)diphenylcarbinolhydrochloride

31. Q27265638

32. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanolhydrochloride

33. 1-azabicyclo[2.2.2]oct-3-yl(diphenyl)methanol Hydrochloride (1:1)

34. 3-quinuclidinemethanol, .alpha.,.alpha.-diphenyl-, Hydrochloride

35. (1-azabicyclo[2.2.2]octan-3-yl)(diphenyl)methanol--hydrogen Chloride (1/1)

36. 1-azabicyclo(2.2.2)octane-3-methanol, .alpha.,.alpha.-diphenyl-, Hydrochloride

37. 1-azabicyclo(2.2.2)octane-3-methanol, .alpha.,.alpha.-diphenyl-, Hydrochloride (1:1)

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₂₄ClNO
Molecular Weight	329.9 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Exact Mass	329.1546421 g/mol
Monoisotopic Mass	329.1546421 g/mol
Topological Polar Surface Area	23.5 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	344
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Histamine Antagonists

Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only. (See all compounds classified as Histamine Antagonists.)