Fasoracetam

Synopsis, Chemistry

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Also known as: 110958-19-5, Fasoracetam [inn], N-(5-oxo-d-prolyl)piperidine, Ns 105 (pharmaceutical), (5r)-5-(piperidine-1-carbonyl)pyrrolidin-2-one, Ns-105

Molecular Formula

C₁₀H₁₆N₂O₂

Molecular Weight

196.25 g/mol

InChI Key

GOWRRBABHQUJMX-MRVPVSSYSA-N

FDA UNII

42O8UF5CJB

Fasoracetam is under investigation in clinical trial NCT03609619 (PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without Mglur Mutations).

1 2D Structure

Fasoracetam

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(5R)-5-(piperidine-1-carbonyl)pyrrolidin-2-one

2.1.2 InChI

InChI=1S/C10H16N2O2/c13-9-5-4-8(11-9)10(14)12-6-2-1-3-7-12/h8H,1-7H2,(H,11,13)/t8-/m1/s1

2.1.3 InChI Key

GOWRRBABHQUJMX-MRVPVSSYSA-N

2.1.4 Canonical SMILES

C1CCN(CC1)C(=O)C2CCC(=O)N2

2.1.5 Isomeric SMILES

C1CCN(CC1)C(=O)[C@H]2CCC(=O)N2

2.2 Other Identifiers

2.2.1 UNII

42O8UF5CJB

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 5-oxo-d-prolinepiperidinamide Monohydrate

2. Ns 105

3. Ns-105

2.3.2 Depositor-Supplied Synonyms

1. 110958-19-5

2. Fasoracetam [inn]

3. N-(5-oxo-d-prolyl)piperidine

4. Ns 105 (pharmaceutical)

5. (5r)-5-(piperidine-1-carbonyl)pyrrolidin-2-one

6. Ns-105

7. (r)-5-(piperidine-1-carbonyl)pyrrolidin-2-one

8. (r)-1-((5-oxo-2-pyrrolidinyl)carbonyl)piperidine

9. Lam-105

10. Nfc1 Anhydrous

11. Nfc-1 Anhydrous

12. Lam105 Anhydrous

13. Lam-105 Anhydrous

14. 42o8uf5cjb

15. Ncgc00182992-01

16. Aevi001

17. Aevi-001

18. Chebi:31592

19. Ns105

20. (+)-1-(((r)-5-oxo-2-pyrrolidinyl)carbonyl)piperidine

21. (5r)-5-(1-piperidinylcarbonyl)-2-pyrrolidinone

22. (r)-1-[(5-oxo-2-pyrrolidinyl)carbonyl]piperidine

23. 2-pyrrolidinone, 5-(1-piperidinylcarbonyl)-, (5r)-

24. Unii-42o8uf5cjb

25. Piperidine, 1-((5-oxo-2-pyrrolidinyl)carbonyl)-, (r)-

26. Dsstox_cid_28781

27. Dsstox_rid_83050

28. Dsstox_gsid_48855

29. Schembl194770

30. Chembl2106179

31. Dtxsid9048855

32. Ex-a736

33. Bcp16788

34. Zinc3779713

35. Tox21_113340

36. Mfcd00875708

37. Ns 105

38. Akos006280726

39. 4-methyl-6-trifluoromethylnicotinicacid

40. Ac-31949

41. Bs-49484

42. Fasoracetam ;aka Ns-105 ;lam-105)

43. Cas-110958-19-5

44. (5r)-5-(piperidine-1-carbonyl) Pyrrolidin-2-one

45. A894820

46. Q5436839

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₀H₁₆N₂O₂
Molecular Weight	196.25 g/mol
XLogP3	0
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	196.121177757 g/mol
Monoisotopic Mass	196.121177757 g/mol
Topological Polar Surface Area	49.4 Å²
Heavy Atom Count	14
Formal Charge	0
Complexity	247
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1