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1. 2101938-42-3
2. M5049
3. Enpatoran [inn]
4. Enpatoran [usan]
5. Unii-7cz390v26x
6. 7cz390v26x
7. 5-[(3r,5s)-3-amino-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile
8. M-5049
9. Enpatoran [who-dd]
10. 5-((3r,5s)-3-amino-5-trifluoromethylpiperidin-1-yl)quinoline-8-carbonitrile
11. 8-quinolinecarbonitrile, 5-((3r,5s)-3-amino-5-(trifluoromethyl)-1-piperidinyl)-
12. 5-((3r,5s)-3-amino-5-(trifluoromethyl)piperidin-1-yl)quinoline-8-carbonitrile
13. Refchem:136984
14. Tlr 7/8 Antagonist M5049
15. Tlr 7/8 Inhibitor M5049
16. M 5049
17. Enpatoran [usan:inn]
18. Who 11880
19. 5-[(3~{r},5~{s})-3-azanyl-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile
20. Enpatoran (usan/inn)
21. Orb1298016
22. Chembl4802159
23. Schembl18980030
24. Schembl29722092
25. Gtpl11307
26. Glxc-23927
27. Ex-a5509
28. Mfcd34471096
29. Akos040759872
30. Compound 73 [wo2017106607a1]
31. Ms-24729
32. Hy-134581
33. Cs-0145642
34. D12261
35. F96161
36. Qlh
| Molecular Weight | 320.31 g/mol |
|---|---|
| Molecular Formula | C16H15F3N4 |
| XLogP3 | 2.7 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 1 |
| Exact Mass | Da |
| Monoisotopic Mass | Da |
| Topological Polar Surface Area | 65.9 |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 472 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
M5049 is a small molecule Toll-like receptor (TLR)7 and TLR8 inhibitor. The drug blocks activation of TLR7/8, thereby stopping immune cell activation, inflammation, and the progression into a cyotkine storm. The drug is currently being investigated against COVID-19.
ABOUT THIS PAGE
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PharmaCompass offers a list of Enpatoran API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Enpatoran manufacturer or Enpatoran supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Enpatoran manufacturer or Enpatoran supplier.
A Enpatoran manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Enpatoran, including repackagers and relabelers. The FDA regulates Enpatoran manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Enpatoran API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Enpatoran supplier is an individual or a company that provides Enpatoran active pharmaceutical ingredient (API) or Enpatoran finished formulations upon request. The Enpatoran suppliers may include Enpatoran API manufacturers, exporters, distributors and traders.
Enpatoran Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Enpatoran GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Enpatoran GMP manufacturer or Enpatoran GMP API supplier for your needs.
A Enpatoran CoA (Certificate of Analysis) is a formal document that attests to Enpatoran's compliance with Enpatoran specifications and serves as a tool for batch-level quality control.
Enpatoran CoA mostly includes findings from lab analyses of a specific batch. For each Enpatoran CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Enpatoran may be tested according to a variety of international standards, such as European Pharmacopoeia (Enpatoran EP), Enpatoran JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Enpatoran USP).
