X
API Suppliers
US DMFs Filed
0
CEP/COS Certifications
JDMFs Filed
0
Other Certificates
Other Suppliers
0
USA (Orange Book)
0
Europe
Canada
Australia
0
South Africa
0
Uploaded Dossiers
0
U.S. Medicaid
0
Annual Reports
0
0
USFDA Orange Book Patents
0
USFDA Exclusivities
0
Blog #PharmaFlow
0
News
0
EDQM
USP
0
JP
0
Other Listed Suppliers
0
0
1. Apo-tiaprofenic
2. Fc 3001
3. Flanid
4. Novo-tiaprofenic
5. Nu-tiaprofenic
6. Pms-tiaprofenic
7. Ru 15060
8. Surgam
9. Surgam Sa
10. Tiaprofenic Acid, Calcium Salt
1. 33005-95-7
2. Surgam
3. Tiaprofensaeure
4. 2-(5-benzoylthiophen-2-yl)propanoic Acid
5. Acido Tiaprofenico
6. Acide Tiaprofenique
7. Acidum Tiaprofenicum
8. 5-benzoyl-alpha-methyl-2-thiopheneacetic Acid
9. 2-(5-benzyl-2-thienyl)propionsaeure
10. Tiaprofen
11. Acide Tiaprofenique [inn-french]
12. Acido Tiaprofenico [inn-spanish]
13. Acidum Tiaprofenicum [inn-latin]
14. Ru 15060
15. 2-[5-(phenylcarbonyl)-2-thienyl]propanoic Acid
16. Fc 3001
17. Tiaprofenate
18. Suralgan
19. Alpha-methyl-5-benzoyl-2-thienylacetic Acid
20. Chebi:32221
21. 5-benzoyl-alpha-methylthiophene-2-acetic Acid
22. 2-(5-benzoyl-2-thienyl)propanoic Acid
23. 1ls1t6r34c
24. Ru-15060
25. 2-(5-benzoyl-thiophen-2-yl)-propionic Acid
26. Dsstox_cid_3665
27. 5-benzoyl-.alpha.-methyl-2-thiopheneacetic Acid
28. Dsstox_rid_77134
29. Dsstox_gsid_23665
30. Surgam Sa
31. Einecs 251-329-3
32. Brn 1380662
33. Unii-1ls1t6r34c
34. Ncgc00016815-01
35. Prestwick_814
36. Cas-33005-95-7
37. 2-(5-benzoylthiophen-2-yl)propanoicacid
38. Prestwick0_000496
39. Prestwick1_000496
40. Prestwick2_000496
41. Prestwick3_000496
42. Epitope Id:131796
43. 2-thiopheneacetic Acid, 5-benzoyl-alpha-methyl-
44. Schembl25639
45. Bspbio_000391
46. 2-thiopheneacetic Acid, 5-benzoyl-.alpha.-methyl-
47. 5-18-08-00405 (beilstein Handbook Reference)
48. Mls002153845
49. Tiaprofenic Acid [mi]
50. Spbio_002312
51. Tiaprofenic Acid [inn]
52. Tiaprofenic Acid [jan]
53. Bpbio1_000431
54. Chembl365795
55. Dtxsid5023665
56. Tiaprofenic Acid [mart.]
57. Tiaprofenic Acid [who-dd]
58. Bdbm223313
59. Hms1569d13
60. Hms2096d13
61. Hms2230e19
62. Hms3372d06
63. Hms3713d13
64. Amy17789
65. Ex-a4101
66. Tox21_110627
67. Mfcd00866089
68. S5661
69. Stl454339
70. (5-benzoyl-2-thienyl)-propionic Acid
71. Akos015969058
72. Tiaprofenic Acid [ep Impurity]
73. Tox21_110627_1
74. Ac-8970
75. Ccg-220496
76. Db01600
77. Tiaprofenic Acid [ep Monograph]
78. Ncgc00179573-03
79. As-77449
80. Smr001233207
81. 2-(5-benzoyl-2-thienyl)propanoic Acid #
82. 2-(5-benzoylthiophen-2-yl)propionic Acid
83. Alpha-(5-benzoyl-2-thienyl)propionic Acid
84. 5-benzoyl-
85. A-methyl-2-thiopheneacetic Acid
86. Hy-106579
87. Cs-0026096
88. Ft-0675220
89. T3175
90. D01325
91. 005t957
92. Q419926
93. Sr-01000841193
94. 2-(5-benzoyl-2-thienyl)propanoic Acid, Aldrichcpr
95. 2-[5-(phenylcarbonyl)thiophen-2-yl]propanoic Acid
96. J-018971
97. Sr-01000841193-2
98. Brd-a72988804-001-03-8
99. Ethyl( Inverted Exclamation Marka)-1-[1-(4-fluorophenyl)ethyl]-1h-imidazole-4-carboxylate
| Molecular Weight | 260.31 g/mol |
|---|---|
| Molecular Formula | C14H12O3S |
| XLogP3 | 3.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Exact Mass | 260.05071541 g/mol |
| Monoisotopic Mass | 260.05071541 g/mol |
| Topological Polar Surface Area | 82.6 Ų |
| Heavy Atom Count | 18 |
| Formal Charge | 0 |
| Complexity | 323 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Tiaprofenic acid is used to treat pain, especially arthritic pain.
Tiaprofenic acid is a non-steroidal anti-inflammatory drug of the arylpropionic acid (profen) class, used to treat pain, especially arthritic pain. The typical adult dose is 300mg twice daily. This drug is not recommended for use in the pediatric population.
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)
M - Musculo-skeletal system
M01 - Antiinflammatory and antirheumatic products
M01A - Antiinflammatory and antirheumatic products, non-steroids
M01AE - Propionic acid derivatives
M01AE11 - Tiaprofenic acid
Absorption
Bioavailability is 90% following oral administration.
Hepatic (10%). Sparingly metabolised in the liver to two inactive metabolites.
1.5-2.5 hours
Tiaprofenic acid belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of a chemical (prostaglandin) which the body produces in response to injury or certain diseases. This prostaglandin would otherwise go on to cause swelling, pain and inflammation.
Market Place
