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Chemistry

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Also known as: 55837-27-9, Tauliz, 4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic acid, Eurelix, Hoe 118, 4-phenoxy-3-(pyrrolidin-1-yl)-5-sulfamoylbenzoic acid
Molecular Formula
C17H18N2O5S
Molecular Weight
362.4  g/mol
InChI Key
UJEWTUDSLQGTOA-UHFFFAOYSA-N
FDA UNII
DQ6KK6GV93

Piretanide
Piretanide is a sulfamoylbenzoic acid belonging to the class of loop diuretics. Piretanide is structurally related to furosemide and bumetanide.
1 2D Structure

Piretanide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic acid
2.1.2 InChI
InChI=1S/C17H18N2O5S/c18-25(22,23)15-11-12(17(20)21)10-14(19-8-4-5-9-19)16(15)24-13-6-2-1-3-7-13/h1-3,6-7,10-11H,4-5,8-9H2,(H,20,21)(H2,18,22,23)
2.1.3 InChI Key
UJEWTUDSLQGTOA-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1CCN(C1)C2=C(C(=CC(=C2)C(=O)O)S(=O)(=O)N)OC3=CC=CC=C3
2.2 Other Identifiers
2.2.1 UNII
DQ6KK6GV93
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic Acid

2. Hoe 118

2.3.2 Depositor-Supplied Synonyms

1. 55837-27-9

2. Tauliz

3. 4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic Acid

4. Eurelix

5. Hoe 118

6. 4-phenoxy-3-(pyrrolidin-1-yl)-5-sulfamoylbenzoic Acid

7. Hoe-118

8. Benzoic Acid, 3-(aminosulfonyl)-4-phenoxy-5-(1-pyrrolidinyl)-

9. S 73 4118

10. 4-phenoxy-3-(1-pyrrolidinyl)-5-sulfamoylbenzoic Acid

11. Dq6kk6gv93

12. Ncgc00016878-01

13. Arlix

14. Cas-55837-27-9

15. Dsstox_cid_3488

16. Dsstox_rid_77050

17. Dsstox_gsid_23488

18. S-734118

19. S-73-4118

20. Piretanido [spanish]

21. Piretanido

22. Piretanidum

23. Piretanidum [inn-latin]

24. Piretanido [inn-spanish]

25. Arelix (tn)

26. Einecs 259-852-9

27. Unii-dq6kk6gv93

28. Brn 5633965

29. Piretanide [usan:inn:ban:jan]

30. Piretanide-[d4]

31. S 734118

32. 3-(aminosulfonyl)-4-phenoxy-5-(1-pyrrolidinyl)-benzoic Acid

33. Piretanide [mi]

34. Piretanide [inn]

35. Piretanide [jan]

36. Acide Phenoxy-4-(1-pyrrolidinyl)-3-sulfamoyl-5 Benzoique [french]

37. Prestwick0_001047

38. Prestwick1_001047

39. Prestwick2_001047

40. Prestwick3_001047

41. Piretanide [usan]

42. Piretanide [mart.]

43. Piretanide [who-dd]

44. Schembl49473

45. Bspbio_000974

46. Mls002154123

47. Piretanide (jan/usan/inn)

48. Spbio_002907

49. Bpbio1_001072

50. Chembl349803

51. Gtpl4742

52. Dtxsid2023488

53. Chebi:32015

54. Piretanide For System Suitability

55. Acide Phenoxy-4-(1-pyrrolidinyl)-3-sulfamoyl-5 Benzoique

56. Piretanide [ep Monograph]

57. Hms1571a16

58. Hms2098a16

59. Hms2230g15

60. Hms3372o22

61. Hms3715a16

62. Zinc3812930

63. Tox21_110661

64. Akos015895445

65. Tox21_110661_1

66. Ccg-221047

67. Db02925

68. Ncgc00016878-02

69. Ncgc00016878-04

70. Smr001233430

71. Hy-119816

72. Ab00514020

73. Cs-0078068

74. Ft-0673944

75. 2-methyl-2-propylpropane-1,3-diyl Dicarbamate

76. D01634

77. 837p279

78. A924106

79. Sr-01000838837

80. 4-phenoxy-3-(pyrrolidinyl)-5-sulfamoylbenzoic Acid

81. Q3905617

82. Sr-01000838837-2

83. W-105543

84. 3-(1-pyrrolidinyl)-4-phenoxy-5-sulphamylbenzoic Acid

85. Brd-k87990216-001-03-7

86. 4-phenoxy-3-(1-pyrrolidinyl)-5-sulphamoylbenzoic Acid

87. F2173-0688

88. 3-(aminosulfonyl)-4-(phenyloxy)-5-pyrrolidin-1-ylbenzoic Acid

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 362.4 g/mol
Molecular Formula C17H18N2O5S
XLogP32.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass362.09364285 g/mol
Monoisotopic Mass362.09364285 g/mol
Topological Polar Surface Area118 Ų
Heavy Atom Count25
Formal Charge0
Complexity564
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Diuretics

Agents that promote the excretion of urine through their effects on kidney function. (See all compounds classified as Diuretics.)


Sodium Potassium Chloride Symporter Inhibitors

Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA. (See all compounds classified as Sodium Potassium Chloride Symporter Inhibitors.)


4.2 ATC Code

C - Cardiovascular system

C03 - Diuretics

C03C - High-ceiling diuretics

C03CA - Sulfonamides, plain

C03CA03 - Piretanide


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ABOUT THIS PAGE

Looking for 55837-27-9 / Piretanide API manufacturers, exporters & distributors?

Piretanide manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Piretanide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Piretanide manufacturer or Piretanide supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Piretanide manufacturer or Piretanide supplier.

PharmaCompass also assists you with knowing the Piretanide API Price utilized in the formulation of products. Piretanide API Price is not always fixed or binding as the Piretanide Price is obtained through a variety of data sources. The Piretanide Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Piretanide

Synonyms

55837-27-9, Tauliz, 4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic acid, Eurelix, Hoe 118, 4-phenoxy-3-(pyrrolidin-1-yl)-5-sulfamoylbenzoic acid

Cas Number

55837-27-9

Unique Ingredient Identifier (UNII)

DQ6KK6GV93

About Piretanide

Piretanide is a sulfamoylbenzoic acid belonging to the class of loop diuretics. Piretanide is structurally related to furosemide and bumetanide.

DSSTox_CID_3488 Manufacturers

A DSSTox_CID_3488 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of DSSTox_CID_3488, including repackagers and relabelers. The FDA regulates DSSTox_CID_3488 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. DSSTox_CID_3488 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of DSSTox_CID_3488 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

DSSTox_CID_3488 Suppliers

A DSSTox_CID_3488 supplier is an individual or a company that provides DSSTox_CID_3488 active pharmaceutical ingredient (API) or DSSTox_CID_3488 finished formulations upon request. The DSSTox_CID_3488 suppliers may include DSSTox_CID_3488 API manufacturers, exporters, distributors and traders.

click here to find a list of DSSTox_CID_3488 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

DSSTox_CID_3488 CEP

A DSSTox_CID_3488 CEP of the European Pharmacopoeia monograph is often referred to as a DSSTox_CID_3488 Certificate of Suitability (COS). The purpose of a DSSTox_CID_3488 CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of DSSTox_CID_3488 EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of DSSTox_CID_3488 to their clients by showing that a DSSTox_CID_3488 CEP has been issued for it. The manufacturer submits a DSSTox_CID_3488 CEP (COS) as part of the market authorization procedure, and it takes on the role of a DSSTox_CID_3488 CEP holder for the record. Additionally, the data presented in the DSSTox_CID_3488 CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the DSSTox_CID_3488 DMF.

A DSSTox_CID_3488 CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. DSSTox_CID_3488 CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of DSSTox_CID_3488 suppliers with CEP (COS) on PharmaCompass.

DSSTox_CID_3488 GMP

DSSTox_CID_3488 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of DSSTox_CID_3488 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right DSSTox_CID_3488 GMP manufacturer or DSSTox_CID_3488 GMP API supplier for your needs.

DSSTox_CID_3488 CoA

A DSSTox_CID_3488 CoA (Certificate of Analysis) is a formal document that attests to DSSTox_CID_3488's compliance with DSSTox_CID_3488 specifications and serves as a tool for batch-level quality control.

DSSTox_CID_3488 CoA mostly includes findings from lab analyses of a specific batch. For each DSSTox_CID_3488 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

DSSTox_CID_3488 may be tested according to a variety of international standards, such as European Pharmacopoeia (DSSTox_CID_3488 EP), DSSTox_CID_3488 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (DSSTox_CID_3488 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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