Find Magnesium Salicylate manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 18917-89-0, Magnesium disalicylate, Magnesiumsalicylate, Magan, Magnesium salicylate anhydrous, Jq69d454n1
Molecular Formula
C14H10MgO6
Molecular Weight
298.53  g/mol
InChI Key
MQHWFIOJQSCFNM-UHFFFAOYSA-L
FDA UNII
JQ69D454N1

Magnesium Salicylate
Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations. Though the recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate tetrahydrate, equivalent to 934.4 mg anhydrous magnesium salicylate), effective pain relief is often found with a half dosage, with reduced anti-inflammatory results.
1 2D Structure

Magnesium Salicylate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
magnesium;2-carboxyphenolate
2.1.2 InChI
InChI=1S/2C7H6O3.Mg/c2*8-6-4-2-1-3-5(6)7(9)10;/h2*1-4,8H,(H,9,10);/q;;+2/p-2
2.1.3 InChI Key
MQHWFIOJQSCFNM-UHFFFAOYSA-L
2.1.4 Canonical SMILES
C1=CC=C(C(=C1)C(=O)O)[O-].C1=CC=C(C(=C1)C(=O)O)[O-].[Mg+2]
2.2 Other Identifiers
2.2.1 UNII
JQ69D454N1
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Keygesic-10

2. Magan

3. Mobidin

4. Momentum (magnesium Salicylate)

2.3.2 Depositor-Supplied Synonyms

1. 18917-89-0

2. Magnesium Disalicylate

3. Magnesiumsalicylate

4. Magan

5. Magnesium Salicylate Anhydrous

6. Jq69d454n1

7. Mobidin

8. Magnesium, Bis[2-(hydroxy-.kappa.o)benzoato-.kappa.o]-, (t-4)-

9. Backache Relief

10. Chebi:6640

11. Bis(salicylato)magnesium; Magan; Magnesium Bis(salicylate); Salicylic Acid, Magnesium Salt

12. Bis(salicylato)magnesium

13. Magnesium Bis(salicylate)

14. Unii-jq69d454n1

15. Magnesium, Bis(2-(hydroxy-.kappa.o)benzoato-.kappa.o)-, (t-4)-

16. Einecs 242-669-3

17. Analate

18. Lorisal

19. Triact

20. Salicylic Acid, Magnesium Salt (2:1)

21. Magnesium;2-carboxyphenolate

22. Schembl9981

23. Chembl2106755

24. Dtxsid00889392

25. Magnesium Salicylate [mi]

26. Magnesium Salicylate (1:2)

27. Akos015901813

28. Db01397

29. Magnesium, Bis(2-hydroxybenzoato-o1,o2)-

30. Q6731407

2.4 Create Date
2011-12-26
3 Chemical and Physical Properties
Molecular Weight 298.53 g/mol
Molecular Formula C14H10MgO6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass298.0327797 g/mol
Monoisotopic Mass298.0327797 g/mol
Topological Polar Surface Area121 Ų
Heavy Atom Count21
Formal Charge0
Complexity133
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Drug and Medication Information
4.1 Drug Indication

Magnesium salicylate is a common analgesic and non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate muscular pain


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


Cyclooxygenase Inhibitors

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (See all compounds classified as Cyclooxygenase Inhibitors.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Central Nervous System Stimulation [PE]; Methylxanthine [EPC]; Xanthines [CS]; Central Nervous System Stimulant [EPC]
5.3 Mechanism of Action

Most NSAIDs act as nonselective inhibitors of the enzyme cyclooxygenase (COX), inhibiting both the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes. COX catalyzes the formation of prostaglandins and thromboxane from arachidonic acid (itself derived from the cellular phospholipid bilayer by phospholipase A2). Prostaglandins act (among other things) as messenger molecules in the process of inflammation.


Listed Suppliers

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Virtual BoothPharm-Rx is a reputed global importer and distributor of pharmaceutical active ingredients.

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Magnesium Salicylate

About the Company : Pharm-Rx has earned an outstanding reputation since its establishment in 1991, serving as a reputable importer and distributor of active ingredients to the pharmaceutical, nutritio...

Pharm-Rx has earned an outstanding reputation since its establishment in 1991, serving as a reputable importer and distributor of active ingredients to the pharmaceutical, nutritional supplement, and food industries. The company maintains an exceptionally selective approach to its suppliers, personally visiting manufacturers overseas to ensure the highest standards. The sustained growth of Pharm-Rx can be attributed to its steadfast commitment to three core values: quality ingredients, competitive pricing, and unparalleled customer service.
Pharm RX

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Magnesium Salicylate

About the Company : DRRPSL (Dr. Raju’s Pharma Solutions, LLC.) a New Jersey-based Corporation, is actively involved in the support of Developing New Drugs and Their Commercialization for both the In...

DRRPSL (Dr. Raju’s Pharma Solutions, LLC.) a New Jersey-based Corporation, is actively involved in the support of Developing New Drugs and Their Commercialization for both the Innovators and Generic Industry in the USA under the leadership of its Executive Team with over five decades of combined expertise in Drug Discovery, Development (NDA, ANDA & OTC), Supply Chain and Regulatory Affairs. We are wholesale distributors licensed in New York, New Jersey, and Pennsylvania.
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Magnesium Salicylate

About the Company : Founded in 2002, JQC (Huayin) Pharmaceutical Co., Ltd. is a private pharmaceutical enterprise, that focus in Salicylic acid series API & intermediates production and research devel...

Founded in 2002, JQC (Huayin) Pharmaceutical Co., Ltd. is a private pharmaceutical enterprise, that focus in Salicylic acid series API & intermediates production and research development. The predecessor was a state-owned corporation-“Northwest Second Synthesis Pharmaceutical”. The company’s register capital is 11.18 million RMB and the current net capital is nearly 150 million RMB. The company passed GMP issued by the State Food and Drug Administration (SFDA) in 2004, 2010 and 2015.Meanwhile, our quality system passed US FDA inspection In January 26, 2013, and NDC code was registered in D&B.
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Magnesium Salicylate

About the Company : Kreative Organics Private Limited is a manufacturer of Active Pharmaceutical Ingredients (APIs) for the world market. Kreative started operations in 1990. Kreative was established ...

Kreative Organics Private Limited is a manufacturer of Active Pharmaceutical Ingredients (APIs) for the world market. Kreative started operations in 1990. Kreative was established by Dr. S. Krishnamohan. Dr. Krishnamohan was formerly with TIFR, BARC, Caltech and NASA. He is a scientist of international repute and runs Kreative with professionalism and a focus on innovation. Kreative maintains strict quality standards and has developed a robust quality system around which all of our products are manufactured. Kreative invested in a state of the art cGMP facility in 2005 and expanded it to a US FDA class facility in 2013.
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ABOUT THIS PAGE

Looking for 18917-89-0 / Magnesium Salicylate API manufacturers, exporters & distributors?

Magnesium Salicylate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Magnesium Salicylate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Magnesium Salicylate manufacturer or Magnesium Salicylate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Magnesium Salicylate manufacturer or Magnesium Salicylate supplier.

PharmaCompass also assists you with knowing the Magnesium Salicylate API Price utilized in the formulation of products. Magnesium Salicylate API Price is not always fixed or binding as the Magnesium Salicylate Price is obtained through a variety of data sources. The Magnesium Salicylate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Magnesium Salicylate

Synonyms

18917-89-0, Magnesium disalicylate, Magnesiumsalicylate, Magan, Magnesium salicylate anhydrous, Jq69d454n1

Cas Number

18917-89-0

Unique Ingredient Identifier (UNII)

JQ69D454N1

About Magnesium Salicylate

Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations. Though the recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate tetrahydrate, equivalent to 934.4 mg anhydrous magnesium salicylate), effective pain relief is often found with a half dosage, with reduced anti-inflammatory results.

Doan's Manufacturers

A Doan's manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Doan's, including repackagers and relabelers. The FDA regulates Doan's manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Doan's API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Doan's manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Doan's Suppliers

A Doan's supplier is an individual or a company that provides Doan's active pharmaceutical ingredient (API) or Doan's finished formulations upon request. The Doan's suppliers may include Doan's API manufacturers, exporters, distributors and traders.

click here to find a list of Doan's suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Doan's USDMF

A Doan's DMF (Drug Master File) is a document detailing the whole manufacturing process of Doan's active pharmaceutical ingredient (API) in detail. Different forms of Doan's DMFs exist exist since differing nations have different regulations, such as Doan's USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Doan's DMF submitted to regulatory agencies in the US is known as a USDMF. Doan's USDMF includes data on Doan's's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Doan's USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Doan's suppliers with USDMF on PharmaCompass.

Doan's NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Doan's as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Doan's API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Doan's as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Doan's and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Doan's NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Doan's suppliers with NDC on PharmaCompass.

Doan's GMP

Doan's Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Doan's GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Doan's GMP manufacturer or Doan's GMP API supplier for your needs.

Doan's CoA

A Doan's CoA (Certificate of Analysis) is a formal document that attests to Doan's's compliance with Doan's specifications and serves as a tool for batch-level quality control.

Doan's CoA mostly includes findings from lab analyses of a specific batch. For each Doan's CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Doan's may be tested according to a variety of international standards, such as European Pharmacopoeia (Doan's EP), Doan's JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Doan's USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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