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Chemistry

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Also known as: Dextromethorphan hydrobromide, 125-69-9, Antussan, Demorphan, Dormethan, Metrorat
Molecular Formula
C18H26BrNO
Molecular Weight
352.3  g/mol
InChI Key
MISZALMBODQYFT-URVXVIKDSA-N
FDA UNII
Z0CG3115FG

Dextromethorphan Hydrobromide
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
1 2D Structure

Dextromethorphan Hydrobromide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1S,9S,10S)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene;hydrobromide
2.1.2 InChI
InChI=1S/C18H25NO.BrH/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H/t15-,17+,18+;/m1./s1
2.1.3 InChI Key
MISZALMBODQYFT-URVXVIKDSA-N
2.1.4 Canonical SMILES
CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC.Br
2.1.5 Isomeric SMILES
CN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)OC.Br
2.2 Other Identifiers
2.2.1 UNII
Z0CG3115FG
2.3 Synonyms
2.3.1 MeSH Synonyms

1. D-methorphan

2. Dextromethorphan

3. Dextromethorphan Hydrobromide

4. Dextromethorphan Hydrobromide, (+-)-isomer

5. Dextromethorphan Hydrobromide, Monohydrate

6. Dextromethorphan Hydrochloride

7. Dextromethorphan, (+-)-isomer

8. Hydrobromide, Dextromethorphan

9. Hydrochloride, Dextromethorphan

10. L-methorphan

11. Levomethorphan

12. Racemethorphan

2.3.2 Depositor-Supplied Synonyms

1. Dextromethorphan Hydrobromide

2. 125-69-9

3. Antussan

4. Demorphan

5. Dormethan

6. Metrorat

7. Medicon

8. Tusilan

9. Tussade

10. D-methorphan Hydrobromide

11. Romilar

12. Methorate Hydrobromide

13. Dextromethorphan Bromide

14. Dextromethorphan (hydrobromide)

15. Dextromethorphan Hydrobromide Anhydrous

16. Ro 1-5470/5

17. Dextromethorphan Hbr

18. D-3-methoxy-n-methylmorphinan Hydrobromide

19. Z0cg3115fg

20. Benylin Dm

21. (1s,9s,10s)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene;hydrobromide

22. Romilar Hydrobromide

23. (9?,13?,14?)-3-methoxy-17-methylmorphinan Hydrobromide

24. Dextroramin P

25. Demorphine

26. Dextrometorphan Hydrobromide

27. Allfen-dm

28. (1s,9s,10r)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene;hydrobromide

29. Nsc-756723

30. Demorphan Hydrobromide

31. Einecs 204-750-1

32. Dextromethorphan Polistirex

33. (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan Hydrobromide

34. Unii-z0cg3115fg

35. Canfodion

36. Cosylan

37. Dormetan

38. Hihustan M.

39. Ro 1-5470

40. Dxm Hbr

41. 9-alpha,13-alpha,14-alpha-morphinan, 3-methoxy-17-methyl-, Hydrobromide

42. Schembl121924

43. Morphinan, 3-methoxy-n-methyl-, Hydrobromide, (+)-

44. Chembl1201004

45. Dtxsid60872346

46. Bcp06595

47. Hy-b0620

48. Dextromethorphan Hbr Anhydrous

49. Mfcd00269810

50. Akos022186323

51. Ccg-212567

52. Nsc 756723

53. Dextromethorphan Hydrobromide [mi]

54. Dextromethorphan Hydrobromide [who-dd]

55. Q27294835

56. (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan Hbr

57. 3-methoxy-17-methyl-9.alpha.,13.alpha.,14.alpha.-morphinan Hbr

58. Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-, Hydrobromide

59. 3-methoxy-17-methyl-9.alpha.,13.alpha.,14.alpha.-morphinan Hydrobromide

60. 9alpha,13alpha,14alpha-morphinan, 3-methoxy-17-methyl-, Hydrobromide (8ci)

61. Morphinan, 3-methoxy-17-methyl-, (9.alpha.,13.alpha.,14.alpha.)-, Hbr

62. Morphinan, 3-methoxy-17-methyl-, (9.alpha.,13.alpha.,14.alpha.)-, Hydrobromide

63. Morphinan, 3-methoxy-17-methyl-, Hydrobromide (1:1),(9.alpha.,13.alpha.,14.alpha.)-

64. (4bs,8as,9s)-3-methoxy-11-methyl-6,7,8,8a,9,10-hexahydro-5h-9,4b-(epiminoethano)phenanthrene Hydrobromide

65. 1887136-04-0

2.4 Create Date
2005-06-08
3 Chemical and Physical Properties
Molecular Weight 352.3 g/mol
Molecular Formula C18H26BrNO
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass351.11978 g/mol
Monoisotopic Mass351.11978 g/mol
Topological Polar Surface Area12.5 Ų
Heavy Atom Count21
Formal Charge0
Complexity370
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameDelsym
Active IngredientDextromethorphan polistirex
Dosage FormSuspension, extended release
RouteOral
Strengtheq 30mg hbr/5ml
Market StatusOver the Counter
CompanyReckitt Benckiser

2 of 4  
Drug NameDextromethorphan polistirex
Active IngredientDextromethorphan polistirex
Dosage FormSuspension, extended release
RouteOral
Strengtheq 30mg hbr/5ml
Market StatusOver the Counter
CompanyTris Pharma

3 of 4  
Drug NameDelsym
Active IngredientDextromethorphan polistirex
Dosage FormSuspension, extended release
RouteOral
Strengtheq 30mg hbr/5ml
Market StatusOver the Counter
CompanyReckitt Benckiser

4 of 4  
Drug NameDextromethorphan polistirex
Active IngredientDextromethorphan polistirex
Dosage FormSuspension, extended release
RouteOral
Strengtheq 30mg hbr/5ml
Market StatusOver the Counter
CompanyTris Pharma

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Excitatory Amino Acid Antagonists

Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists. (See all compounds classified as Excitatory Amino Acid Antagonists.)


Antitussive Agents

Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally. (See all compounds classified as Antitussive Agents.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Sigma-1 Receptor Agonists [MoA]; Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]; Uncompetitive NMDA Receptor Antagonists [MoA]; Sigma-1 Agonist [EPC]

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BY:ONEIRO LIFECARE PVT LTD.(VADODARA-GUJARAT); MFGR.GST: 24AAACO7069C1ZN,TAX INV:","address":"UNIT NO.229,2 ND FLOOR, WADALA UDYOG BHAVAN,PLOT 8,","city":"MUMBAI","supplier":"GRADIENT PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"MANILA NORTH HARBOR","customer":"UNDISCLOSED","customerCountry":"PHILIPPINES","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"90","totalValueFC":"8827.7","currency":"USD","unitRateINR":7801.0962,"date":"01-Oct-2025","totalValueINR":"780109.62","totalValueInUsd":"8827.7","indian_port":"JNPT","hs_no":"29339990","bill_no":"5823579","productDescription":"API","marketType":"","country":"PHILIPPINES","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"UNIT NO.229,2 ND FLOOR, WADALA UDYOG BHAVAN,PLOT 8,, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1759775400,"product":"DEXTROMETHORPHAN HYDROBROMIDE USP (PHARMACEUTICAL ALLOPATHIC RAW MATERIAL)","address":"1ST FLOOR ABS TOWERS","city":"BARODA","supplier":"ONEIRO LIFECARE PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"LAHORE","customer":"UNDISCLOSED","customerCountry":"PAKISTAN","quantity":"20.00","actualQuantity":"20","unit":"KGS","unitRateFc":"135","totalValueFC":"2539.3","currency":"USD","unitRateINR":11220,"date":"07-Oct-2025","totalValueINR":"224400","totalValueInUsd":"2539.3","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"5954498","productDescription":"API","marketType":"","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"1ST FLOOR ABS TOWERS, BARODA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1760121000,"product":"DEXTROMETHORPHAN HYDROBROMIDE USP (MFG:ONEIRO LIFECARE PVT.LTD GST:24AAACO7069C1ZN TAX INV: 579\/25-26 , DATE: 30.08.20","address":"UNIT NO.229,2 ND FLOOR, WADALA UDYOG BHAVAN,PLOT 8,","city":"MUMBAI","supplier":"GRADIENT PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"LIMA -","customer":"UNDISCLOSED","customerCountry":"PERU","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"80","totalValueFC":"15932.9","currency":"USD","unitRateINR":7040.0003500000003,"date":"11-Oct-2025","totalValueINR":"1408000.07","totalValueInUsd":"15932.9","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"6075241","productDescription":"API","marketType":"","country":"PERU","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"UNIT NO.229,2 ND FLOOR, WADALA UDYOG BHAVAN,PLOT 8,, MUMBAI","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1761244200,"product":"DEXTROMETHORPHAN HYDROBROMIDE USP","address":"PLOT NO.174,PROGRESSIVE INDUSTRIAL","city":"TALUQ,MEDAK DIST.,A.P.","supplier":"HY GRO CHEMICALS PHARMTEK PRIVATE LTD","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"UNDISCLOSED","customerCountry":"INDONESIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"75","totalValueFC":"110755.4","currency":"USD","unitRateINR":6525,"date":"24-Oct-2025","totalValueINR":"9787500","totalValueInUsd":"110755.4","indian_port":"Hyderabad ICD","hs_no":"29339990","bill_no":"6396487","productDescription":"API","marketType":"","country":"INDONESIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad ICD","supplierAddress":"PLOT NO.174,PROGRESSIVE INDUSTRIAL, TALUQ,MEDAK DIST.,A.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1761762600,"product":"BULK DRUGS - DEXTROMETHORPHAN HYDROBROMIDE USP","address":"WOCKHARDT TOWERS, BANDRA KURLA","city":"MUMBAI, MAHARASHTRA.","supplier":"WOCKHARDT LTD","supplierCountry":"INDIA","foreign_port":"LAHORE","customer":"SIZA INTERNATIONAL PVT LTD","customerCountry":"PAKISTAN","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"75","totalValueFC":"7217.4","currency":"N\/A","unitRateINR":6378.0396000000001,"date":"30-Oct-2025","totalValueINR":"637803.96","totalValueInUsd":"7217.4","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"6561066","productDescription":"API","marketType":"","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"WOCKHARDT TOWERS, BANDRA KURLA, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q4","strtotime":1761849000,"product":"DEXTROMETHORPHAN HYDROBROMIDE USP(TAX INV. NO. H\/25-26\/288 DT. 13.10.2025, MFG- HY-GRO CHEMICALS ,GSTIN-36AAACH6012J1ZT)","address":"203 SEFA HOUSE A,PALI MALLA ROAD","city":"BANDRA WEST,MAHARASHTRA","supplier":"CRIMSON INTERNATIONAL","supplierCountry":"INDIA","foreign_port":"BAGDAD, METROPOLITAN","customer":"AL ALAMEAH CO FOR HUMAN","customerCountry":"IRAQ","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"100","totalValueFC":"48.9","currency":"USD","unitRateINR":8641.3999999999996,"date":"31-Oct-2025","totalValueINR":"4320.7","totalValueInUsd":"48.9","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"6571156","productDescription":"API","marketType":"","country":"IRAQ","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"203 SEFA HOUSE A,PALI MALLA ROAD, BANDRA WEST,MAHARASHTRA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1746642600,"product":"(RE-IMPORT CARGO) DEXTROMETHORPHAN HYDROBROMIDE BP (25KGS X05 DRMS)(22.277KGS X 01 DRUM)(14.739 X 01 DRM) & (8.10 KGS X(RE-IMPORT CARGO) DEXTROMETHORPHAN HYDROBROMIDE BP (25KGS X","address":"A-201\/202, NAVBHARAT EST.,","city":"MUMBAI ,MAHARASHTRA","supplier":"SUNWARD PHARMACEUTICAL PTE LTD","supplierCountry":"INDIA","foreign_port":"SINGAPORE","customer":"GEMINI EXPORTS","customerCountry":"INDIA","quantity":"170.10","actualQuantity":"170.101","unit":"KGS","unitRateFc":"117.3","totalValueFC":"20040.2","currency":"USD","unitRateINR":"10037.8","date":"08-May-2025","totalValueINR":"1707438.58","totalValueInUsd":"20040.2","indian_port":"JNPT","hs_no":"29339990","bill_no":"9934700","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"SINGAPORE","supplierAddress":"11 WAN LEE ROAD,SINGAPORE 627943 SDNF SDNF SINGAPORE","customerAddress":"A-201\/202, NAVBHARAT EST.,"}]
03-Jan-2022
31-Oct-2025
KGS
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

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API Imports and Exports

Importing Country Total Quantity
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Drugs in Development

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Details:

Mighty Chews consisting, Dextromethorphan HBr, is the first and only over-the-counter medicated children's soft chew for cough relief.


Lead Product(s): Dextromethorphan Hydrobromide,Inapplicable

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Mighty Chews

Study Phase: Approved FDFProduct Type: Controlled Substance

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 30, 2024

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01

Reckitt Benckiser

United Kingdom
arrow
DDL Conference
Not Confirmed

Reckitt Benckiser

United Kingdom
arrow
DDL Conference
Not Confirmed

Details : Mighty Chews consisting, Dextromethorphan HBr, is the first and only over-the-counter medicated children's soft chew for cough relief.

Product Name : Mighty Chews

Product Type : Controlled Substance

Upfront Cash : Inapplicable

September 30, 2024

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Details:

Promethazine HCl and Dextromethorphan Hydrobromide-Generic is an approved oral solution, which is indicated for the patients suffering from cough.


Lead Product(s): Promethazine Hydrochloride,Dextromethorphan Hydrobromide

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Promethazine HCl-Dextromethorphan HBr-Generic

Study Phase: Approved FDFProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 13, 2024

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02

DDL Conference
Not Confirmed
DDL Conference
Not Confirmed

Details : Promethazine HCl and Dextromethorphan Hydrobromide-Generic is an approved oral solution, which is indicated for the patients suffering from cough.

Product Name : Promethazine HCl-Dextromethorphan HBr-Generic

Product Type : Miscellaneous

Upfront Cash : Inapplicable

September 13, 2024

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  • Deals

Details:

This diverse portfolio of products includes Breathe Right® Nasal Strips, the world’s #1 nasal strip, and Children’s Dimetapp®, the #1 pharmacist-recommended brand for children's cough and cold products, as well as Anbesol®, Alavert®, Dristan®, Primatene Tablets® and FiberCon®.


Lead Product(s): Brompheniramine Maleate,Dextromethorphan Hydrobromide,Phenylephrine Hydrochloride

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Dimetapp

Study Phase: Approved FDFProduct Type: Miscellaneous

Sponsor: Foundation Consumer Healthcare

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement July 16, 2020

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03

GSK

United Kingdom
arrow
DDL Conference
Not Confirmed

GSK

United Kingdom
arrow
DDL Conference
Not Confirmed

Details : This diverse portfolio of products includes Breathe Right® Nasal Strips, the world’s #1 nasal strip, and Children’s Dimetapp®, the #1 pharmacist-recommended brand for children's cough and cold products, as well as Anbesol®, Alavert®, Dristan®, P...

Product Name : Dimetapp

Product Type : Miscellaneous

Upfront Cash : Undisclosed

July 16, 2020

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Details:

Dextromethorphan HBr is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Cough.


Lead Product(s): Dextromethorphan Hydrobromide,Inapplicable

Therapeutic Area: Pulmonary/Respiratory Diseases Brand Name: Undisclosed

Study Phase: Phase IVProduct Type: Controlled Substance

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable January 08, 2016

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04

Pfizer Inc

U.S.A
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DDL Conference
Not Confirmed

Pfizer Inc

U.S.A
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DDL Conference
Not Confirmed

Details : Dextromethorphan HBr is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Cough.

Product Name : Undisclosed

Product Type : Controlled Substance

Upfront Cash : Inapplicable

January 08, 2016

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Details:

Dextromethorphan HBr is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Pseudobulbar Palsy.


Lead Product(s): Dextromethorphan Hydrobromide,Quinidine

Therapeutic Area: Neurology Brand Name: Undisclosed

Study Phase: Phase IVProduct Type: Controlled Substance

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable July 14, 2015

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05

DDL Conference
Not Confirmed
DDL Conference
Not Confirmed

Details : Dextromethorphan HBr is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Pseudobulbar Palsy.

Product Name : Undisclosed

Product Type : Controlled Substance

Upfront Cash : Inapplicable

July 14, 2015

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  • Development Update

Details:

Dextromethorphan HBr is a Controlled Substance drug candidate, which is currently being evaluated in clinical studies for the treatment of Arthritis, Rheumatoid.


Lead Product(s): Dextromethorphan Hydrobromide,Inapplicable

Therapeutic Area: Immunology Brand Name: Undisclosed

Study Phase: UndisclosedProduct Type: Controlled Substance

Sponsor: TSH Biopharm Corporation Limited

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 20, 2015

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06

Taichung Veterans General Hospital

Country
arrow
DDL Conference
Not Confirmed

Taichung Veterans General Hospital

Country
arrow
DDL Conference
Not Confirmed

Lead Product(s) : Dextromethorphan Hydrobromide,Inapplicable

Therapeutic Area : Immunology

Highest Development Status : Undisclosed

Partner/Sponsor/Collaborator : TSH Biopharm Corporation Limited

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Dextromethorphan HBr is a Controlled Substance drug candidate, which is currently being evaluated in clinical studies for the treatment of Arthritis, Rheumatoid.

Product Name : Undisclosed

Product Type : Controlled Substance

Upfront Cash : Inapplicable

February 20, 2015

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Details:

BIRT 2584 XX is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.


Lead Product(s): BIRT 2584 XX,Warfarin Sodium,Omeprazole,Dextromethorphan Hydrobromide,Caffeine,Midazolam Hydrochloride,Vitamin K1

Therapeutic Area: Undisclosed Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Undisclosed

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable October 06, 2014

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07

DDL Conference
Not Confirmed
DDL Conference
Not Confirmed

Details : BIRT 2584 XX is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

Product Name : Undisclosed

Product Type : Undisclosed

Upfront Cash : Inapplicable

October 06, 2014

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  • Development Update

Details:

Acetaminophen is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Common Cold.


Lead Product(s): Paracetamol,Pseudoephedrine Hydrochloride,Dextromethorphan Hydrobromide,Chlorpheniramine Maleate

Therapeutic Area: Infections and Infectious Diseases Brand Name: Undisclosed

Study Phase: Phase IVProduct Type: Miscellaneous

Sponsor: Sino-American Tianjin Smith Kline & French Laboratories Ltd

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 22, 2014

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08

GSK

United Kingdom
arrow
DDL Conference
Not Confirmed

GSK

United Kingdom
arrow
DDL Conference
Not Confirmed

Details : Acetaminophen is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Common Cold.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

September 22, 2014

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Details:

Tipranavir is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.


Lead Product(s): Tipranavir,Ritonavir,Caffeine,Warfarin Sodium,Vitamin K1,Omeprazole,Dextromethorphan Hydrobromide,Midazolam,

Therapeutic Area: Undisclosed Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 18, 2014

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09

DDL Conference
Not Confirmed
DDL Conference
Not Confirmed

Details : Tipranavir is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

September 18, 2014

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Details:

Faldaprevir is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.


Lead Product(s): Faldaprevir,Caffeine,Warfarin Sodium,Vitamin K1,Omeprazole,Dextromethorphan Hydrobromide,Midazolam Hydrochloride,Digoxin

Therapeutic Area: Undisclosed Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable July 08, 2014

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10

DDL Conference
Not Confirmed
DDL Conference
Not Confirmed

Details : Faldaprevir is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

July 08, 2014

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Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDF Dossiers

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01

Dextromethorphan Hydrobromide

Brand Name : Sinuclear Cough Syrup

Dosage Form : SOL

Dosage Strength : 10mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

Regulatory Info : RX

Registration Country : USA

BROMPHENIRAMINE MALEATE; DEXTROMETHORPHAN HYDROBROMIDE; PSEUDOEPHEDRINE HYDROCHLORIDE

Brand Name : BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE

Dosage Form : SYRUP;ORAL

Dosage Strength : 2MG/5ML;10MG/5ML;30MG/5ML

Packaging :

Approval Date : 2018-12-04

Application Number : 207676

Regulatory Info : RX

Registration Country : USA

Dr Reddy Company Banner

03

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

Regulatory Info : OTC

Registration Country : USA

DEXTROMETHORPHAN HYDROBROMIDE; GUAIFENESIN

Brand Name : GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE

Dosage Form : TABLET, EXTENDED RELEASE;ORAL

Dosage Strength : 30MG;600MG

Packaging :

Approval Date : 2023-08-01

Application Number : 217340

Regulatory Info : OTC

Registration Country : USA

Dr Reddy Company Banner

04

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

Regulatory Info : OTC

Registration Country : USA

DEXTROMETHORPHAN HYDROBROMIDE; GUAIFENESIN

Brand Name : GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE

Dosage Form : TABLET, EXTENDED RELEASE;ORAL

Dosage Strength : 60MG;1.2GM

Packaging :

Approval Date : 2023-08-01

Application Number : 217340

Regulatory Info : OTC

Registration Country : USA

Dr Reddy Company Banner

05

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothOctavius Pharma has been empowering lives since 1980 by providing quality products like DC granules, APIs and FDFs.

Flag India
Digital Content Digital Content

Regulatory Info :

Registration Country : India

Paracetamol; Caffeine; Phenylephrine Hydrochloride; Chlorpheniramine Maleate; Dextromethorphan Hydrobromide

Brand Name : Paracetamol; Caffeine; Phenylephrine Hydrochloride; Chlorpheniramine Maleate; Dextromethorphan Hydrobromide

Dosage Form : Tablet

Dosage Strength : 500MG; 30MG; 10MG; 2MG; 10MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : India

Octavius Pharma

06

Ah Robins

Colombia
DDL Conference
Not Confirmed
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Ah Robins

Colombia
arrow
DDL Conference
Not Confirmed

BROMPHENIRAMINE MALEATE; DEXTROMETHORPHAN HYDROBROMIDE; PSEUDOEPHEDRINE HYDROCHLORIDE

Brand Name : DIMETANE-DX

Dosage Form : SYRUP;ORAL

Dosage Strength : 2MG/5ML;10MG/5ML;30MG/5ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

Packaging :

Approval Date : 1984-08-24

Application Number : 19279

Regulatory Info : DISCN

Registration Country : USA

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07

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE; PROMETHAZINE HYDROCHLORIDE

Brand Name : PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE

Dosage Form : SYRUP;ORAL

Dosage Strength : 15MG/5ML;6.25MG/5ML

Packaging :

Approval Date : 1984-04-02

Application Number : 11265

Regulatory Info : RX

Registration Country : USA

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08

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE; QUINIDINE SULFATE

Brand Name : NUEDEXTA

Dosage Form : CAPSULE;ORAL

Dosage Strength : 20MG;10MG

Packaging :

Approval Date : 2010-10-29

Application Number : 21879

Regulatory Info : RX

Registration Country : USA

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09

Reckitt Benckiser

United Kingdom
DDL Conference
Not Confirmed
arrow

Reckitt Benckiser

United Kingdom
arrow
DDL Conference
Not Confirmed

DEXTROMETHORPHAN POLISTIREX

Brand Name : DELSYM

Dosage Form : SUSPENSION, EXTENDED RELEASE;ORAL

Dosage Strength : EQ 30MG HYDROBROMIDE/5ML

Packaging :

Approval Date : 1982-10-08

Application Number : 18658

Regulatory Info : OTC

Registration Country : USA

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10

Reckitt Benckiser

United Kingdom
DDL Conference
Not Confirmed
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Reckitt Benckiser

United Kingdom
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DDL Conference
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DEXTROMETHORPHAN HYDROBROMIDE; GUAIFENESIN

Brand Name : MUCINEX DM

Dosage Form : TABLET, EXTENDED RELEASE;ORAL

Dosage Strength : 60MG;1.2GM

Packaging :

Approval Date : 2004-04-29

Application Number : 21620

Regulatory Info : OTC

Registration Country : USA

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  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

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RLD : No

TE Code : AA

BROMPHENIRAMINE MALEATE; DEXTROMETHORPHAN HYDROBROMIDE; PSEUDOEPHEDRINE HYDROCHLORIDE

Brand Name : BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE

Dosage Form : SYRUP;ORAL

Dosage Strength : 2MG/5ML;10MG/5ML;30MG/5ML

Approval Date : 2018-12-04

Application Number : 207676

RX/OTC/DISCN : RX

RLD : No

TE Code : AA

Dr Reddy Company Banner

02

DR REDDYS

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

RLD : No

TE Code :

DEXTROMETHORPHAN HYDROBROMIDE; GUAIFENESIN

Brand Name : GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE

Dosage Form : TABLET, EXTENDED RELEASE;ORAL

Dosage Strength : 30MG;600MG

Approval Date : 2023-08-01

Application Number : 217340

RX/OTC/DISCN : OTC

RLD : No

TE Code :

Dr Reddy Company Banner

03

DR REDDYS

India
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Flag India
Digital Content Digital Content

RLD : No

TE Code :

DEXTROMETHORPHAN HYDROBROMIDE; GUAIFENESIN

Brand Name : GUAIFENESIN AND DEXTROMETHORPHAN HYDROBROMIDE

Dosage Form : TABLET, EXTENDED RELEASE;ORAL

Dosage Strength : 60MG;1.2GM

Approval Date : 2023-08-01

Application Number : 217340

RX/OTC/DISCN : OTC

RLD : No

TE Code :

Dr Reddy Company Banner

04

ACELLA

U.S.A
DDL Conference
Not Confirmed
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ACELLA

U.S.A
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DDL Conference
Not Confirmed

BROMPHENIRAMINE MALEATE; DEXTROMETHORPHAN HYDROBROMIDE; PSEUDOEPHEDRINE HYDROCHLORIDE

Brand Name : BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE

Dosage Form : SYRUP;ORAL

Dosage Strength : 2MG/5ML;10MG/5ML;30MG/5ML

Approval Date : 2016-09-20

Application Number : 203375

RX/OTC/DISCN : RX

RLD : No

TE Code : AA

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05

ROBINS AH

Colombia
DDL Conference
Not Confirmed
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ROBINS AH

Colombia
arrow
DDL Conference
Not Confirmed

BROMPHENIRAMINE MALEATE; DEXTROMETHORPHAN HYDROBROMIDE; PSEUDOEPHEDRINE HYDROCHLORIDE

Brand Name : DIMETANE-DX

Dosage Form : SYRUP;ORAL

Dosage Strength : 2MG/5ML;10MG/5ML;30MG/5ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

Approval Date : 1984-08-24

Application Number : 19279

RX/OTC/DISCN : DISCN

RLD : Yes

TE Code :

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DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

BROMPHENIRAMINE MALEATE; DEXTROMETHORPHAN HYDROBROMIDE; PSEUDOEPHEDRINE HYDROCHLORIDE

Brand Name : BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE

Dosage Form : SYRUP;ORAL

Dosage Strength : 2MG/5ML;10MG/5ML;30MG/5ML

Approval Date : 2020-07-14

Application Number : 210647

RX/OTC/DISCN : RX

RLD : No

TE Code : AA

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07

AMNEAL

U.S.A
DDL Conference
Not Confirmed
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AMNEAL

U.S.A
arrow
DDL Conference
Not Confirmed

DEXTROMETHORPHAN POLISTIREX

Brand Name : DEXTROMETHORPHAN POLISTIREX

Dosage Form : SUSPENSION, EXTENDED RELEASE;ORAL

Dosage Strength : EQ 30MG HYDROBROMIDE/5ML

Approval Date : 2017-07-28

Application Number : 203133

RX/OTC/DISCN : OTC

RLD : No

TE Code :

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08

RB HLTH

United Kingdom
DDL Conference
Not Confirmed
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RB HLTH

United Kingdom
arrow
DDL Conference
Not Confirmed

DEXTROMETHORPHAN POLISTIREX

Brand Name : DELSYM

Dosage Form : SUSPENSION, EXTENDED RELEASE;ORAL

Dosage Strength : EQ 30MG HYDROBROMIDE/5ML

Approval Date : 1982-10-08

Application Number : 18658

RX/OTC/DISCN : OTC

RLD : Yes

TE Code :

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09

WOCKHARDT

India
DDL Conference
Not Confirmed
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WOCKHARDT

India
arrow
DDL Conference
Not Confirmed

BROMPHENIRAMINE MALEATE; DEXTROMETHORPHAN HYDROBROMIDE; PSEUDOEPHEDRINE HYDROCHLORIDE

Brand Name : BROMFED-DM

Dosage Form : SYRUP;ORAL

Dosage Strength : 2MG/5ML;10MG/5ML;30MG/5ML

Approval Date : 1988-12-22

Application Number : 89681

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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10

HALSEY

Country
DDL Conference
Not Confirmed
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HALSEY

Country
arrow
DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE; PROMETHAZINE HYDROCHLORIDE

Brand Name : PHERAZINE DM

Dosage Form : SYRUP;ORAL

Dosage Strength : 15MG/5ML;6.25MG/5ML

Approval Date : 1987-03-02

Application Number : 88913

RX/OTC/DISCN : DISCN

RLD : No

TE Code :

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Europe

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DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Paracetamol; Chlorphenamine Maleate; Phenylephrine Hydrochloride; Vitamin C; Dextrometorphan Hydrobromide

Brand Name : Propalgina Plus Powder For Oral Solution

Dosage Form : Oral Solution

Dosage Strength :

Packaging :

Approval Date : 1987-03-01

Application Number : 56999

Regulatory Info : Authorized

Registration Country : Spain

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02

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Paracetamol; Pseudoephedrine Sulfate; Dextromethorphan Hydrobromide

Brand Name : Larobeta

Dosage Form : Powder For Oral Solution

Dosage Strength : 500MG; 30MG; 15 MG

Packaging :

Approval Date : 2012-04-15

Application Number : 75767

Regulatory Info : Cancelled

Registration Country : Spain

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03

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Sodium Benzoate; Dextromethorphan Hydrobromide

Brand Name : Dr. Andreu'S Pills

Dosage Form : Lozenge

Dosage Strength : 2MG; 15 MG

Packaging :

Approval Date : 1989-06-01

Application Number : 57875

Regulatory Info : Cancelled

Registration Country : Spain

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04

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide; Diphenhydramine Hydrochloride

Brand Name : Cinfatos Night

Dosage Form : Solution

Dosage Strength : 1.33MG; 2MG

Packaging :

Approval Date : 2020-12-22

Application Number : 85664

Regulatory Info : Authorized

Registration Country : Spain

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05

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Cinfatos

Dosage Form : Oral Solution

Dosage Strength : 2MG

Packaging :

Approval Date : 1988-07-01

Application Number : 57623

Regulatory Info : Authorized

Registration Country : Spain

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06

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Paracetamol; Chlorphenamine Maleate; Dextromethorphan Hydrobromide

Brand Name : Normogrip Antitusive Granulated For Oral Solution

Dosage Form : Oral Solution

Dosage Strength :

Packaging :

Approval Date : 2023-03-01

Application Number : 88698

Regulatory Info : Authorized

Registration Country : Spain

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07

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Minustosan

Dosage Form : Syrup

Dosage Strength : 1.5MG

Packaging :

Approval Date : 2021-06-04

Application Number : 84688

Regulatory Info : Authorized

Registration Country : Spain

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08

TAD Pharma GmbH

Germany
DDL Conference
Not Confirmed
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TAD Pharma GmbH

Germany
arrow
DDL Conference
Not Confirmed

Paracetamol; Pseudoephedrine Hydrochloride; Dextromethorphan Hydrobromide

Brand Name : Daleron Cold3

Dosage Form : Film Coated Tablet

Dosage Strength : 325MG; 30MG; 15MG

Packaging :

Approval Date : 2022-01-07

Application Number :

Regulatory Info : Authorised

Registration Country : Malta

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09

Aurovitas Spain, Sau

Country
DDL Conference
Not Confirmed
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Aurovitas Spain, Sau

Country
arrow
DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Aurotos

Dosage Form : Oral Solution

Dosage Strength : 15MG

Packaging :

Approval Date : 2014-04-11

Application Number : 78676

Regulatory Info : Cancelled

Registration Country : Spain

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10

Lainco Sa

Country
DDL Conference
Not Confirmed
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Lainco Sa

Country
arrow
DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Laitos

Dosage Form : Syrup

Dosage Strength : 3MG

Packaging :

Approval Date : 2009-06-03

Application Number : 70997

Regulatory Info : Authorized

Registration Country : Spain

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Canada

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HALEON CANADA ULC

United Kingdom
DDL Conference
Not Confirmed
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HALEON CANADA ULC

United Kingdom
arrow
DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : BUCKLEY'S COLD & SINUS 24 HOUR PACK

Dosage Form : KIT

Dosage Strength : 15MG

Packaging :

Approval Date :

Application Number : 2493802

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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02

HALEON CANADA ULC

United Kingdom
DDL Conference
Not Confirmed
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HALEON CANADA ULC

United Kingdom
arrow
DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : BUCKLEY'S DRY COUGH EXTRA STRENGTH

Dosage Form : SOLUTION

Dosage Strength : 15MG/5ML

Packaging :

Approval Date :

Application Number : 2511320

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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03

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : BENYLIN EXTRA STRENGTH DRY COUGH

Dosage Form : SYRUP

Dosage Strength : 30MG/10ML

Packaging : 100ML/250ML

Approval Date :

Application Number : 1944738

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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04

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : CHILDREN'S TYLENOL COLD AND COUGH

Dosage Form : SUSPENSION

Dosage Strength : 7.5MG/5ML

Packaging : 100ML

Approval Date :

Application Number : 2039990

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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05

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : BENYLIN EXTRA STRENGTH ALL-IN-ONE COUGH, COLD & FLU

Dosage Form : SYRUP

Dosage Strength : 15MG/15ML

Packaging : 180 ML

Approval Date :

Application Number : 2245710

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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06

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : BENYLIN EXTRA STRENGTH COUGH & CHEST CONGESTION

Dosage Form : SYRUP

Dosage Strength : 15MG/5ML

Packaging : 100ML/250ML

Approval Date :

Application Number : 2265419

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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07

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : NYQUIL KIDS COUGH & COLD

Dosage Form : SYRUP

Dosage Strength : 15MG/15ML

Packaging :

Approval Date :

Application Number : 2273330

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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08

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : NYQUIL COLD & FLU ALCOHOL FREE

Dosage Form : SYRUP

Dosage Strength : 30MG/30ML

Packaging :

Approval Date :

Application Number : 2551667

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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09

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : COLD AND FLU-IN-ONE EXTRA STRENGTH

Dosage Form : TABLET

Dosage Strength : 15MG

Packaging : Dec-24

Approval Date :

Application Number : 2281147

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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10

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

DEXTROMETHORPHAN HYDROBROMIDE

Brand Name : COLD AND SINUS COMPLETE LIQUID GELS

Dosage Form : CAPSULE

Dosage Strength : 10MG

Packaging : 10/20/30/40

Approval Date :

Application Number : 2349523

Regulatory Info : NON-PRESCRIPTION DRUGS

Registration Country : Canada

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South Africa

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Dextromethorphan Hydrobromide

Brand Name : Sinuclear Cough Syrup

Dosage Form : SOL

Dosage Strength : 10mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

Aspen API Comapny Banner

02

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Sinustat Flu Syrup

Dosage Form : SYR

Dosage Strength : 15mg

Packaging : 200X1mg

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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03

Adcock Ingram Limited

South Africa
DDL Conference
Not Confirmed
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Adcock Ingram Limited

South Africa
arrow
DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Dilinct Dry Cough Syrup

Dosage Form : SYR

Dosage Strength : 15mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

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04

Adcock Ingram Limited

South Africa
DDL Conference
Not Confirmed
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Adcock Ingram Limited

South Africa
arrow
DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Dilinct Dry Cough Syrup

Dosage Form : SYR

Dosage Strength : 15mg/5ml

Packaging : 200X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

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05

Adcock Ingram Limited

South Africa
DDL Conference
Not Confirmed
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Adcock Ingram Limited

South Africa
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DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Cepacol Sore Throat And Cough Relief Discs

Dosage Form : LOZ

Dosage Strength : 4.98mg

Packaging : 16X1mg

Approval Date :

Application Number :

Regulatory Info : Generic

Registration Country : South Africa

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Cipla Medpro (Pty) Ltd

South Africa
DDL Conference
Not Confirmed
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Cipla Medpro (Pty) Ltd

South Africa
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DDL Conference
Not Confirmed

Dextromethorphan HBr

Brand Name : Broncol Cough Linctus

Dosage Form : SYR

Dosage Strength : 30mg/10 ml

Packaging : 200X1mg/10 ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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07

Cipla Medpro (Pty) Ltd

South Africa
DDL Conference
Not Confirmed
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Cipla Medpro (Pty) Ltd

South Africa
arrow
DDL Conference
Not Confirmed

Dextromethorphan HBr

Brand Name : Broncol Cough Linctus

Dosage Form : SYR

Dosage Strength : 30mg/10 ml

Packaging : 100X1mg/10 ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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08

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Demazin Flu

Dosage Form : EFT

Dosage Strength : 20mg

Packaging : 12X1mg

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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09

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Benylin Dry Cough

Dosage Form : SYR

Dosage Strength : 15mg/5ml

Packaging : 100X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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10

DDL Conference
Not Confirmed
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DDL Conference
Not Confirmed

Dextromethorphan Hydrobromide

Brand Name : Benylin Dry Cough

Dosage Form : SYR

Dosage Strength : 15mg/5ml

Packaging : 200X1mg/5ml

Approval Date :

Application Number :

Regulatory Info : Originator

Registration Country : South Africa

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - SUSPENSION, EXTENDED RELEASE;ORAL - ...DOSAGE - SUSPENSION, EXTENDED RELEASE;ORAL - EQ 30MG HYDROBROMIDE/5ML

USFDA APPLICATION NUMBER - 18658

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 30MG...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 30MG;600MG

USFDA APPLICATION NUMBER - 21620

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DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 60MG...DOSAGE - TABLET, EXTENDED RELEASE;ORAL - 60MG;1.2GM

USFDA APPLICATION NUMBER - 21620

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DOSAGE - SYRUP;ORAL - 2MG/5ML;10MG/5ML;30MG/5...DOSAGE - SYRUP;ORAL - 2MG/5ML;10MG/5ML;30MG/5ML

USFDA APPLICATION NUMBER - 88811

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ABOUT THIS PAGE

Looking for 125-69-9 / Dextromethorphan Hydrobromide API manufacturers, exporters & distributors?

Dextromethorphan Hydrobromide manufacturers, exporters & distributors 1

52

PharmaCompass offers a list of Dextromethorphan Hydrobromide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Dextromethorphan Hydrobromide manufacturer or Dextromethorphan Hydrobromide supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Dextromethorphan Hydrobromide manufacturer or Dextromethorphan Hydrobromide supplier.

PharmaCompass also assists you with knowing the Dextromethorphan Hydrobromide API Price utilized in the formulation of products. Dextromethorphan Hydrobromide API Price is not always fixed or binding as the Dextromethorphan Hydrobromide Price is obtained through a variety of data sources. The Dextromethorphan Hydrobromide Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Dextromethorphan Hydrobromide

Synonyms

125-69-9, Antussan, Demorphan, Dormethan, Metrorat, Medicon

Cas Number

125-69-9

Unique Ingredient Identifier (UNII)

Z0CG3115FG

About Dextromethorphan Hydrobromide

Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.

Dextromethorphan hydrobromide anhydrous Manufacturers

A Dextromethorphan hydrobromide anhydrous manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Dextromethorphan hydrobromide anhydrous, including repackagers and relabelers. The FDA regulates Dextromethorphan hydrobromide anhydrous manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Dextromethorphan hydrobromide anhydrous API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Dextromethorphan hydrobromide anhydrous manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Dextromethorphan hydrobromide anhydrous Suppliers

A Dextromethorphan hydrobromide anhydrous supplier is an individual or a company that provides Dextromethorphan hydrobromide anhydrous active pharmaceutical ingredient (API) or Dextromethorphan hydrobromide anhydrous finished formulations upon request. The Dextromethorphan hydrobromide anhydrous suppliers may include Dextromethorphan hydrobromide anhydrous API manufacturers, exporters, distributors and traders.

click here to find a list of Dextromethorphan hydrobromide anhydrous suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Dextromethorphan hydrobromide anhydrous USDMF

A Dextromethorphan hydrobromide anhydrous DMF (Drug Master File) is a document detailing the whole manufacturing process of Dextromethorphan hydrobromide anhydrous active pharmaceutical ingredient (API) in detail. Different forms of Dextromethorphan hydrobromide anhydrous DMFs exist exist since differing nations have different regulations, such as Dextromethorphan hydrobromide anhydrous USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Dextromethorphan hydrobromide anhydrous DMF submitted to regulatory agencies in the US is known as a USDMF. Dextromethorphan hydrobromide anhydrous USDMF includes data on Dextromethorphan hydrobromide anhydrous's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Dextromethorphan hydrobromide anhydrous USDMF is kept confidential to protect the manufacturer’s intellectual property.

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Dextromethorphan hydrobromide anhydrous JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Dextromethorphan hydrobromide anhydrous Drug Master File in Japan (Dextromethorphan hydrobromide anhydrous JDMF) empowers Dextromethorphan hydrobromide anhydrous API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Dextromethorphan hydrobromide anhydrous JDMF during the approval evaluation for pharmaceutical products. At the time of Dextromethorphan hydrobromide anhydrous JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

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Dextromethorphan hydrobromide anhydrous KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Dextromethorphan hydrobromide anhydrous Drug Master File in Korea (Dextromethorphan hydrobromide anhydrous KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Dextromethorphan hydrobromide anhydrous. The MFDS reviews the Dextromethorphan hydrobromide anhydrous KDMF as part of the drug registration process and uses the information provided in the Dextromethorphan hydrobromide anhydrous KDMF to evaluate the safety and efficacy of the drug.

After submitting a Dextromethorphan hydrobromide anhydrous KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Dextromethorphan hydrobromide anhydrous API can apply through the Korea Drug Master File (KDMF).

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Dextromethorphan hydrobromide anhydrous CEP

A Dextromethorphan hydrobromide anhydrous CEP of the European Pharmacopoeia monograph is often referred to as a Dextromethorphan hydrobromide anhydrous Certificate of Suitability (COS). The purpose of a Dextromethorphan hydrobromide anhydrous CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Dextromethorphan hydrobromide anhydrous EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Dextromethorphan hydrobromide anhydrous to their clients by showing that a Dextromethorphan hydrobromide anhydrous CEP has been issued for it. The manufacturer submits a Dextromethorphan hydrobromide anhydrous CEP (COS) as part of the market authorization procedure, and it takes on the role of a Dextromethorphan hydrobromide anhydrous CEP holder for the record. Additionally, the data presented in the Dextromethorphan hydrobromide anhydrous CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Dextromethorphan hydrobromide anhydrous DMF.

A Dextromethorphan hydrobromide anhydrous CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Dextromethorphan hydrobromide anhydrous CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

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Dextromethorphan hydrobromide anhydrous WC

A Dextromethorphan hydrobromide anhydrous written confirmation (Dextromethorphan hydrobromide anhydrous WC) is an official document issued by a regulatory agency to a Dextromethorphan hydrobromide anhydrous manufacturer, verifying that the manufacturing facility of a Dextromethorphan hydrobromide anhydrous active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Dextromethorphan hydrobromide anhydrous APIs or Dextromethorphan hydrobromide anhydrous finished pharmaceutical products to another nation, regulatory agencies frequently require a Dextromethorphan hydrobromide anhydrous WC (written confirmation) as part of the regulatory process.

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Dextromethorphan hydrobromide anhydrous NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Dextromethorphan hydrobromide anhydrous as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Dextromethorphan hydrobromide anhydrous API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Dextromethorphan hydrobromide anhydrous as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Dextromethorphan hydrobromide anhydrous and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Dextromethorphan hydrobromide anhydrous NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Dextromethorphan hydrobromide anhydrous suppliers with NDC on PharmaCompass.

Dextromethorphan hydrobromide anhydrous GMP

Dextromethorphan hydrobromide anhydrous Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Dextromethorphan hydrobromide anhydrous GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Dextromethorphan hydrobromide anhydrous GMP manufacturer or Dextromethorphan hydrobromide anhydrous GMP API supplier for your needs.

Dextromethorphan hydrobromide anhydrous CoA

A Dextromethorphan hydrobromide anhydrous CoA (Certificate of Analysis) is a formal document that attests to Dextromethorphan hydrobromide anhydrous's compliance with Dextromethorphan hydrobromide anhydrous specifications and serves as a tool for batch-level quality control.

Dextromethorphan hydrobromide anhydrous CoA mostly includes findings from lab analyses of a specific batch. For each Dextromethorphan hydrobromide anhydrous CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Dextromethorphan hydrobromide anhydrous may be tested according to a variety of international standards, such as European Pharmacopoeia (Dextromethorphan hydrobromide anhydrous EP), Dextromethorphan hydrobromide anhydrous JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Dextromethorphan hydrobromide anhydrous USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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