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1. 513t9qrh4d
2. Bbb-006
3. 400090-20-2
4. Unii-513t9qrh4d
5. Ac 100
6. D-00006
7. L-aspartic Acid, L-threonyl-l-.alpha.-aspartyl-l-leucyl-l-glutaminyl-l-.alpha.-glutamyl-l-arginylglycyl-l-.alpha.-aspartyl-l-asparaginyl-l-.alpha.-aspartyl-l-isoleucyl-l-seryl-l-prolyl-l-phenylalanyl-l-serylglycyl-l-.alpha.-aspartylglycyl-l-glutaminyl-l-prolyl-l-phenylalanyl-l-lysyl-
8. L-aspartic Acid, L-threonyl-l-alpha-aspartyl-l-leucyl-l-glutaminyl-l-alpha-glutamyl-l-arginylglycyl-l-alpha-aspartyl-l-asparaginyl-l-alpha-aspartyl-l-isoleucyl-l-seryl-l-prolyl-l-phenylalanyl-l-serylglycyl-l-alpha-aspartylglycyl-l-glutaminyl-l-prolyl-l-phenylalanyl-l-lysyl-
9. (2s)-2-(((2s)-6-amino-2-(((2s)-2-(((2s)-1-((2s)-5-amino-2-((2-(((2s)-2-((2-(((2s)-2-(((2s)-2-(((2s)-1-((2s)-2-(((2s,3s)-2-(((2s)-2-(((2s)-4-amino-2-(((2s)-2-((2-(((2s)-2-(((2s)-2-(((2s)-5-amino-2-(((2s)-2-(((2s)-2-(((2s)-2-amino-3-hydroxy-butanoyl)amino)-4-hydroxy-4-oxo-butanoyl)amino)-4-methyl-pentanoyl)amino)-5-oxo-pentanoyl)amino)-5-hydroxy-5-oxo-pentanoyl)amino)-5-guanidino-pentanoyl)amino)acetyl)amino)-4-hydroxy-4-oxo-butanoyl)amino)-4-oxo-butanoyl)amino)-4-hydroxy-4-oxo-butanoyl)amino)-3-methyl-pentanoyl)amino)-3-hydroxy-propanoyl)pyrrolidine-2-carbonyl)amino)-3-phenyl-propanoyl)amino)-3-hydroxy-propanoyl)amino)acetyl)amino)-4-hydroxy-4-oxo-butanoyl)amino)acetyl)amino)-5-oxo-pentanoyl)pyrrolidine-2-carbonyl)amino)-3-phenyl-propanoyl)amino)hexanoyl)amino)butanedioic Acid
10. Ac-100
11. Dtn
12. Da-52435
| Molecular Weight | 2538.6 g/mol |
|---|---|
| Molecular Formula | C107H160N30O42 |
| XLogP3 | -18.1 |
| Hydrogen Bond Donor Count | 38 |
| Hydrogen Bond Acceptor Count | 45 |
| Rotatable Bond Count | 84 |
| Exact Mass | Da |
| Monoisotopic Mass | Da |
| Topological Polar Surface Area | 1190 |
| Heavy Atom Count | 179 |
| Formal Charge | 0 |
| Complexity | 5900 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 21 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in periodontal disease.
In several preclinical models, AC-100 has demonstrated potent and selective dental tissue and bone formation activity, however the exact mechanism is not known. One study (PMID:15153459) showed that AC-100 enhances dental pulp stem cell (DPSC) proliferation by down-regulating P16, accompanied by up-regulation of ubiquitin protein ligase E3A and human ubiquitin-related protein SUMO-1. Enhanced cell proliferation required intact RGD and SGDG motifs in the peptide. This study shows that AC-100 can promote DPSC proliferation, with a potential role in pulp repair.
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PharmaCompass offers a list of Dentonin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Dentonin manufacturer or Dentonin supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Dentonin manufacturer or Dentonin supplier.
PharmaCompass also assists you with knowing the Dentonin API Price utilized in the formulation of products. Dentonin API Price is not always fixed or binding as the Dentonin Price is obtained through a variety of data sources. The Dentonin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Dentonin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Dentonin, including repackagers and relabelers. The FDA regulates Dentonin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Dentonin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Dentonin supplier is an individual or a company that provides Dentonin active pharmaceutical ingredient (API) or Dentonin finished formulations upon request. The Dentonin suppliers may include Dentonin API manufacturers, exporters, distributors and traders.
Dentonin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Dentonin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Dentonin GMP manufacturer or Dentonin GMP API supplier for your needs.
A Dentonin CoA (Certificate of Analysis) is a formal document that attests to Dentonin's compliance with Dentonin specifications and serves as a tool for batch-level quality control.
Dentonin CoA mostly includes findings from lab analyses of a specific batch. For each Dentonin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Dentonin may be tested according to a variety of international standards, such as European Pharmacopoeia (Dentonin EP), Dentonin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Dentonin USP).
