Find Cyclopentolate Hydrochloride manufacturers, exporters & distributors on PharmaCompass

Cyclopentolate Hydrochloride

Cyclopentolate Hydrochloride

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

10 API Suppliers, 2 USDMF, 2 CEP/COS, 1 JDMF, 2 EU WC, 6 NDC API, 6 Listed Suppliers

PRICE INFORMATION

API Reference Price, API Exports, API Imports

DOSSIERs // Finished Dosage Formulations

23 Dossiers, 14 FDA Orange Book, 2 Europe, 4 Canada, 1 South Africa, 2 Listed Dossiers

DRUG PRODUCT COMPOSITION

SOLUTION/DROPS;OPHTHALMIC - 2%, SOLUTION/DROPS;OPHTHALMIC - 0.5%, SOLUTION/DROPS;OPHTHALMIC - 1%

SOLUTION/DROPS;OPHTHALMIC - 2%
SOLUTION/DROPS;OPHTHALMIC - 0.5%
SOLUTION/DROPS;OPHTHALMIC - 1%

RELATED EXCIPIENT COMPANIES

Suppliers, 3 Actylis, 2 Finar, 1 Microlex e.U, 1 Nanjing Well Pharmaceutical

EXCIPIENTS BY APPLICATIONS

5 Parenteral, 2 Solubilizers, 1 Controlled & Modified Release

GLOBAL SALES INFORMATION

14 US Medicaid Prescriptions, 2 Finished Drug Prices

MARKET PLACE

4 APIs, 1 DOSSIERS // FDF

ANALYTICAL SOLUTION(s)

1 EDQM Standards, 1 USP Standards, 1 Other Ref. Standards

DIGITAL CONTENT

4 News

4 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

1,857

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

3.00

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 5870-29-1, Cyclopentolate hcl, Cyplegin, Cyclogyl, 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate hydrochloride, Ak-pentolate

Molecular Formula

C₁₇H₂₆ClNO₃

Molecular Weight

327.8 g/mol

InChI Key

RHKZVMUBMXGOLL-UHFFFAOYSA-N

A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.

1 2D Structure

Cyclopentolate Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate;hydrochloride

2.1.2 InChI

InChI=1S/C17H25NO3.ClH/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17;/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3;1H

2.1.3 InChI Key

RHKZVMUBMXGOLL-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN(C)CCOC(=O)C(C1=CC=CC=C1)C2(CCCC2)O.Cl

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Cyclogyl

2. Cyclopentolate

2.2.2 Depositor-Supplied Synonyms

1. 5870-29-1

2. Cyclopentolate Hcl

3. Cyplegin

4. Cyclogyl

5. 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate Hydrochloride

6. Ak-pentolate

7. Mydrilate

8. Pentolair

9. Cyclopentolate (hydrochloride)

10. Cyclopentolatehcl

11. 5870-29-1 (hcl)

12. Mls000069583

13. Chebi:4025

14. Beta-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate Hydrochloride

15. 2-(dimethylamino)ethyl 1-hydroxy-alpha-phenylcyclopentaneacetate Hydrochloride

16. 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate;hydrochloride

17. Cyclopentolate For System Suitability

18. Cylate

19. Nsc-756706

20. 60452-44-0

21. Akpentolate

22. Smr000058810

23. Zyklolat

24. 60452-46-2

25. 2-(dimethylamino)ethyl (+-)-1-hydroxy-alpha-phenylcyclopentaneacetate Hydrochloride

26. Dsstox_cid_25390

27. Dsstox_rid_80847

28. Dsstox_gsid_45390

29. Cicloplegicedol

30. Ciclolux

31. Skiacol

32. Alnide

33. 0uxd5v5g6v

34. 6d6x07d6bn

35. Tsiklopentolat Hydrochloride;cyclogyl Hydrochloride;dl-cyclopentolate Hydrochloride

36. Benzeneacetic Acid, Alpha-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride, (-)-

37. Cyclopentolate Hydrochloride, (+)-

38. Cyclopentolate Hydrochloride, (-)-

39. 736i6971te

40. Einecs 227-521-8

41. Sr-01000003121

42. Unii-736i6971te

43. Cyclogyl (tn)

44. Cyclopentolate Hydrochloride [usp:jan]

45. Opera_id_69

46. Ncgc00016661-01

47. (+-)-cyclopentolate Hcl

48. Unii-0uxd5v5g6v

49. 2-(2-(1-hydroxycyclopentyl)-2-phenylacetoxy)ethyldimethylammonium Chloride

50. Cas-5870-29-1

51. Crimson Glory Rose Resinoid

52. Unii-6d6x07d6bn

53. Schembl24612

54. Mls001148637

55. Mls001332539

56. Mls001332540

57. Spectrum1500212

58. Regid_for_cid_22162

59. Cyclopentolate Hcl;ak-pentolate

60. Chembl1200473

61. Dtxsid9045390

62. Hy-b1621a

63. Hms1571k12

64. Hms1920a22

65. Pharmakon1600-01500212

66. Amy23400

67. Bcp21337

68. Einecs 262-240-4

69. Einecs 262-242-5

70. Tox21_110550

71. Ccg-39635

72. Mfcd00079048

73. Nsc756706

74. S5921

75. 2-(dimethylamino)ethyl (+)-(1-hydroxycyclopentyl)phenylacetate Hydrochloride

76. Akos015901379

77. Tox21_110550_1

78. Nsc 756706

79. Benzeneacetic Acid, Alpha-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride

80. Cyclopentaneacetic Acid, 1-hydroxy-alpha-phenyl-, 2-(dimethylamino)ethyl Ester, Hydrochloride

81. Cyclopentolate Hydrochloride (jp17/usp)

82. Ncgc00018213-06

83. Ncgc00094635-01

84. Ncgc00094635-02

85. Ncgc00094635-03

86. Ncgc00094635-04

87. Ac-27486

88. As-49330

89. Benzeneacetic Acid, Alpha-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride, (+-)-

90. Db-053247

91. Cs-0013554

92. Ft-0603161

93. D01002

94. H10247

95. 870c291

96. Sr-01000003121-4

97. Q27266147

98. 2-(dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate Hydrochloride

99. Cyclopentolate Hydrochloride, European Pharmacopoeia (ep) Reference Standard

100. 2-(dimethylamino)ethyl (-)-(1-hydroxycyclopentyl)phenylacetate Hydrochloride

101. 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate;hydron;chloride

102. 2-dimethylaminoethyl 1-hydroxy-

103. A-phenylcyclopentaneacetate,cyclopentolate Hydrochloride

104. Alpha-(1-hydroxycyclopentyl)benzeneacetic Acid 2-(dimethylamino)ethyl Ester Hydrochloride

105. Cyclopentolate For System Suitability, European Pharmacopoeia (ep) Reference Standard

106. Cyclopentolate Hydrochloride, United States Pharmacopeia (usp) Reference Standard

107. Benzeneacetic Acid, .alpha.-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride (1:1)

108. Benzeneacetic Acid,

109. A-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl Ester, Hydrochloride, (-)-

2.3 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₇H₂₆ClNO₃
Molecular Weight	327.8 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	327.1601214 g/mol
Monoisotopic Mass	327.1601214 g/mol
Topological Polar Surface Area	49.8 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	331
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Akpentolate
Active Ingredient	Cyclopentolate hydrochloride
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	1%
Market Status	Prescription
Company	Akorn

2 of 4
Drug Name	Pentolair
Active Ingredient	Cyclopentolate hydrochloride
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	1%
Market Status	Prescription
Company	Bausch And Lomb

3 of 4
Drug Name	Akpentolate
Active Ingredient	Cyclopentolate hydrochloride
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	1%
Market Status	Prescription
Company	Akorn

4 of 4
Drug Name	Pentolair
Active Ingredient	Cyclopentolate hydrochloride
Dosage Form	Solution/drops
Route	Ophthalmic
Strength	1%
Market Status	Prescription
Company	Bausch And Lomb

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Muscarinic Antagonists

Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. (See all compounds classified as Muscarinic Antagonists.)

Parasympatholytics

Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)

Mydriatics

Agents that dilate the pupil. They may be either sympathomimetics or parasympatholytics. (See all compounds classified as Mydriatics.)