Find Cyclin D1 manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as:
Molecular Formula
C43H71N9O11S2
Molecular Weight
954.2  g/mol
InChI Key
KQNLWNLMABECAI-RDEFYCSLSA-N

Cyclin D1
Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.
1 2D Structure

Cyclin D1

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]propanoyl]amino]-3-hydroxybutanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoic acid
2.1.2 InChI
InChI=1S/C43H71N9O11S2/c1-22(2)17-28(44)37(56)48-30(18-23(3)4)38(57)45-20-33(54)46-25(7)36(55)52-35(26(8)53)42(61)50-32(21-64)41(60)47-29(15-16-65-9)39(58)49-31(19-27-13-11-10-12-14-27)40(59)51-34(24(5)6)43(62)63/h10-14,22-26,28-32,34-35,53,64H,15-21,44H2,1-9H3,(H,45,57)(H,46,54)(H,47,60)(H,48,56)(H,49,58)(H,50,61)(H,51,59)(H,52,55)(H,62,63)/t25-,26?,28-,29-,30-,31-,32-,34-,35-/m0/s1
2.1.3 InChI Key
KQNLWNLMABECAI-RDEFYCSLSA-N
2.1.4 Canonical SMILES
CC(C)CC(C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(C)C(=O)NC(C(C)O)C(=O)NC(CS)C(=O)NC(CCSC)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)C)C(=O)O)N
2.1.5 Isomeric SMILES
C[C@@H](C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Bcl 1 Proto Oncogene Products

2. Bcl 1 Proto Oncogene Proteins

3. Bcl-1 Proto-oncogene Products

4. Bcl-1 Proto-oncogene Proteins

5. Bcl-1, Proto-oncogene Protein

6. Bcl1 Proto Oncogene Proteins

7. Bcl1 Proto-oncogene Proteins

8. C Bcl 1 Proteins

9. C-bcl-1 Proteins

10. C-bcl-1, Proto-oncogene Proteins

11. Ccnd1 Protein

12. Prad1 Protein

13. Proto Oncogene Products Bcl 1

14. Proto Oncogene Protein Bcl 1

15. Proto Oncogene Proteins C Bcl 1

16. Proto-oncogene Products Bcl-1

17. Proto-oncogene Products, Bcl-1

18. Proto-oncogene Protein Bcl-1

19. Proto-oncogene Proteins C-bcl-1

20. Proto-oncogene Proteins, Bcl-1

21. Proto-oncogene Proteins, Bcl1

2.3 Create Date
2013-07-05
3 Chemical and Physical Properties
Molecular Weight 954.2 g/mol
Molecular Formula C43H71N9O11S2
XLogP3-0.3
Hydrogen Bond Donor Count12
Hydrogen Bond Acceptor Count14
Rotatable Bond Count29
Exact Mass953.47144646 g/mol
Monoisotopic Mass953.47144646 g/mol
Topological Polar Surface Area343 Ų
Heavy Atom Count65
Formal Charge0
Complexity1600
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Looking for 136601-57-5 / Cyclin D1 API manufacturers, exporters & distributors?

Cyclin D1 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Cyclin D1 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cyclin D1 manufacturer or Cyclin D1 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cyclin D1 manufacturer or Cyclin D1 supplier.

PharmaCompass also assists you with knowing the Cyclin D1 API Price utilized in the formulation of products. Cyclin D1 API Price is not always fixed or binding as the Cyclin D1 Price is obtained through a variety of data sources. The Cyclin D1 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Cyclin D1

Cas Number

136601-57-5

About Cyclin D1

Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.

Cyclin D1 Manufacturers

A Cyclin D1 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cyclin D1, including repackagers and relabelers. The FDA regulates Cyclin D1 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cyclin D1 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Cyclin D1 Suppliers

A Cyclin D1 supplier is an individual or a company that provides Cyclin D1 active pharmaceutical ingredient (API) or Cyclin D1 finished formulations upon request. The Cyclin D1 suppliers may include Cyclin D1 API manufacturers, exporters, distributors and traders.

Cyclin D1 GMP

Cyclin D1 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cyclin D1 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cyclin D1 GMP manufacturer or Cyclin D1 GMP API supplier for your needs.

Cyclin D1 CoA

A Cyclin D1 CoA (Certificate of Analysis) is a formal document that attests to Cyclin D1's compliance with Cyclin D1 specifications and serves as a tool for batch-level quality control.

Cyclin D1 CoA mostly includes findings from lab analyses of a specific batch. For each Cyclin D1 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cyclin D1 may be tested according to a variety of international standards, such as European Pharmacopoeia (Cyclin D1 EP), Cyclin D1 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cyclin D1 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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