CXA-10

Synopsis, Chemistry

DEVELOPMENTS

1 Drug(s) in Development

1 Drug(s) in Development

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 10-nitro oleic acid, 875685-46-4, (e)-10-nitrooctadec-9-enoic acid, Cxa-10, 10-nitro-9e-octadecenoic acid, 88127-53-1

Molecular Formula

C₁₈H₃₃NO₄

Molecular Weight

327.5 g/mol

InChI Key

WRADPCFZZWXOTI-BMRADRMJSA-N

FDA UNII

1N19AGY57Y

CXA-10 is under investigation in clinical trial NCT03422510 (FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS)).

1 2D Structure

CXA-10

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(E)-10-nitrooctadec-9-enoic acid

2.1.2 InChI

InChI=1S/C18H33NO4/c1-2-3-4-5-8-11-14-17(19(22)23)15-12-9-6-7-10-13-16-18(20)21/h15H,2-14,16H2,1H3,(H,20,21)/b17-15+

2.1.3 InChI Key

WRADPCFZZWXOTI-BMRADRMJSA-N

2.1.4 Canonical SMILES

CCCCCCCCC(=CCCCCCCCC(=O)O)[N+](=O)[O-]

2.1.5 Isomeric SMILES

CCCCCCCC/C(=C\CCCCCCCC(=O)O)/[N+](=O)[O-]

2.2 Other Identifiers

2.2.1 UNII

1N19AGY57Y

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 10-nitro-9(e)-octadec-9-enoic Acid

2. 10-nitro-octadec-9-cis-enoic Acid

3. 10-nitro-octadec-9-enoic Acid

4. 9-nitro-octadec-9-cis-enoic Acid

5. Cxa-10

6. Nitro-oleic Acid

7. No2-oa

2.3.2 Depositor-Supplied Synonyms

1. 10-nitro Oleic Acid

2. 875685-46-4

3. (e)-10-nitrooctadec-9-enoic Acid

4. Cxa-10

5. 10-nitro-9e-octadecenoic Acid

6. 88127-53-1

7. Oa-no2

8. 10-nitroelaidic Acid

9. (9e)-10-nitrooctadecenoic Acid

10. 10-nitrooleate

11. 9-octadecenoic Acid, 10-nitro-, (9e)-

12. 10-nitro-9(e)-octadec-9-enoic Acid

13. E-10-no2-18:1

14. 1n19agy57y

15. Chembl561371

16. Chebi:86285

17. 9-octadecenoic Acid, 10-nitro-

18. 10-nitro-oleic Acid

19. 10-nitroelaidate

20. E-10-nitrooleic Acid

21. 10-nitro-9e-octadecenoate

22. Unii-1n19agy57y

23. (9e)-10-nitrooctadecenoate

24. 10-nitro-9-octadecenoic Acid

25. Schembl1018141

26. (e)-10-nitrooctadec-9-enoate

27. Dtxsid401347887

28. 9-nitro-9-trans-octadecenoic Acid

29. 10-nitro-9-trans-octadecenoic Acid

30. Bdbm50295049

31. Lmfa01120003

32. Zinc40331256

33. (9e)-10-nitrooctadec-9-enoic Acid

34. Db15026

35. Hy-101559

36. Cs-0021707

37. F70901

38. A903619

39. Sr-01000946993

40. Sr-01000946993-1

41. Q27159052

42. Lna

2.4 Create Date

2008-07-10

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₃₃NO₄
Molecular Weight	327.5 g/mol
XLogP3	6.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	15
Exact Mass	327.24095853 g/mol
Monoisotopic Mass	327.24095853 g/mol
Topological Polar Surface Area	83.1 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	347
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1