Crofelemer

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

2 NDC API

2 NDC API

DEVELOPMENTS

25 Drug(s) in Development

25 Drug(s) in Development

PRICE INFORMATION

API Reference Price, API Exports

DOSSIERs // Finished Dosage Formulations

1 Dossiers, 1 FDA Orange Book

GLOBAL SALES INFORMATION

5 US Medicaid Prescriptions, 1 Finished Drug Prices

PATENTS

2 US Patents

2 US Patents

DIGITAL CONTENT

10 News

10 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

7,631

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

7.00

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: 148465-45-6, Cid 17397714, Zinc9497828, Akos016487279, Z164754034, 923916-82-9

Molecular Formula

C₁₈H₁₆N₂O₃

Molecular Weight

308.3 g/mol

InChI Key

JDNAIBCYTQGWFC-UHFFFAOYSA-N

1 2D Structure

Crofelemer

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

N-[(2-methoxyphenyl)methyl]-5-phenyl-1,2-oxazole-3-carboxamide

2.1.2 InChI

InChI=1S/C18H16N2O3/c1-22-16-10-6-5-9-14(16)12-19-18(21)15-11-17(23-20-15)13-7-3-2-4-8-13/h2-11H,12H2,1H3,(H,19,21)

2.1.3 InChI Key

JDNAIBCYTQGWFC-UHFFFAOYSA-N

2.1.4 Canonical SMILES

COC1=CC=CC=C1CNC(=O)C2=NOC(=C2)C3=CC=CC=C3

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. 148465-45-6

2. Cid 17397714

3. Zinc9497828

4. Akos016487279

5. Z164754034

6. 923916-82-9

2.3 Create Date

2007-11-13

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₁₆N₂O₃
Molecular Weight	308.3 g/mol
XLogP3	3.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	308.11609238 g/mol
Monoisotopic Mass	308.11609238 g/mol
Topological Polar Surface Area	64.4 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	385
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1