API SUPPLIERS

API Suppliers

1

US DMFs Filed

1

CEP/COS Certifications

0

JDMFs Filed

0

Other Certificates

0

Other Suppliers

0

API REF. PRICE (USD / KG)

0

API Market Place

0

INTERMEDIATES

0

DOSSIERS // FDF

USA (Orange Book)

0

Europe

0

Canada

0

Australia

0

South Africa

0

Uploaded Dossiers

0

GLOBAL SALES (USD Million)

U.S. Medicaid

0

Annual Reports

0

FDF Market Place

0

EXCIPIENTS

0

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

0

USFDA Exclusivities

0

DIGITAL CONTENT

Blog #PharmaFlow

0

News

1

REF STANDARD

EDQM

0

USP

0

JP

0

Other Listed Suppliers

0

SERVICES

0

Also known as: 58524-83-7, Rs-2386, 8y88cp83mk, [2-[(1s,2s,4r,8s,9s,11s,12r,13s,19s)-12,19-difluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] cyclopropanecarboxylate, Ciprocinonida, Ciprocinonidum

Molecular Formula

C₂₈H₃₄F₂O₇

Molecular Weight

520.6 g/mol

InChI Key

TZBDXWBBMOEVPI-XBQQDWOSSA-N

FDA UNII

8Y88CP83MK

1 2D Structure

Ciprocinonide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

[2-[(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] cyclopropanecarboxylate

2.1.2 InChI

InChI=1S/C28H34F2O7/c1-24(2)36-22-11-16-17-10-19(29)18-9-15(31)7-8-25(18,3)27(17,30)20(32)12-26(16,4)28(22,37-24)21(33)13-35-23(34)14-5-6-14/h7-9,14,16-17,19-20,22,32H,5-6,10-13H2,1-4H3/t16-,17-,19-,20-,22+,25-,26-,27-,28+/m0/s1

2.1.3 InChI Key

TZBDXWBBMOEVPI-XBQQDWOSSA-N

2.1.4 Canonical SMILES

CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)COC(=O)C6CC6)C)O)F)C)F)C

2.1.5 Isomeric SMILES

C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)COC(=O)C5CC5)C[C@@H](C6=CC(=O)C=C[C@@]63C)F)F)O

2.2 Other Identifiers

2.2.1 UNII

8Y88CP83MK

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 58524-83-7

2. Rs-2386

3. 8y88cp83mk

4. [2-[(1s,2s,4r,8s,9s,11s,12r,13s,19s)-12,19-difluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] Cyclopropanecarboxylate

5. Ciprocinonida

6. Ciprocinonidum

7. Rs 2386

8. Ciprocinonide [usan:inn]

9. Ciprocinonidum [inn-latin]

10. Unii-8y88cp83mk

11. Ciprocinonida [inn-spanish]

12. Einecs 261-307-5

13. Ciprocinonide [inn]

14. Ciprocinonide (usan/inn)

15. Ciprocinonide [usan]

16. Ciprocinonide [mart.]

17. Schembl122617

18. Ciprocinonide [who-dd]

19. Chembl2105934

20. Dtxsid601024166

21. Zinc4212545

22. 16alpha,17-dimethylmethylendioxy-6alpha,9-difluor-11beta,21-dihydroxy-1,4-pregnadien-3,20-dion-21-cyclopropancarboxylat

23. 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione Cyclic 16,17-acetal With Acetone, 21-cyclopropanecarboxylate

24. D03520

25. Q27271198

26. 6.alpha.,9-difluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione Cyclic 16,17-acetal With Acetone, 21-cyclopropanecarboxylate

27. Pregna-1,4-diene-3,20-dione, 21-((cyclopropylcarbonyl)oxy)-6,9-difluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6.alpha.,11.beta.,16.alpha.)-

28. Pregna-1,4-diene-3,20-dione, 21-((cyclopropylcarbonyl)oxy)-6,9-difluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-

2.4 Create Date

2006-11-22

3 Chemical and Physical Properties

Molecular Formula	C₂₈H₃₄F₂O₇
Molecular Weight	520.6 g/mol
XLogP3	3.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	5
Exact Mass	520.22725974 g/mol
Monoisotopic Mass	520.22725974 g/mol
Topological Polar Surface Area	99.1 Å²
Heavy Atom Count	37
Formal Charge	0
Complexity	1140
Isotope Atom Count	0
Defined Atom Stereocenter Count	9
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1