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Chloropyramine Hydrochloride

Chloropyramine Hydrochloride

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Also known as: 6170-42-9, Chloropyramine hcl, Alergosan, Nilfan, Halopyramine hydrochloride, Chlorpyramine hydrochloride

Molecular Formula

C₁₆H₂₁Cl₂N₃

Molecular Weight

326.3 g/mol

InChI Key

VEYWWAGBHABATA-UHFFFAOYSA-N

FDA UNII

FWA92Z14NN

1 2D Structure

Chloropyramine Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

N'-[(4-chlorophenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine;hydrochloride

2.1.2 InChI

InChI=1S/C16H20ClN3.ClH/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14;/h3-10H,11-13H2,1-2H3;1H

2.1.3 InChI Key

VEYWWAGBHABATA-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN(C)CCN(CC1=CC=C(C=C1)Cl)C2=CC=CC=N2.Cl

2.2 Other Identifiers

2.2.1 UNII

FWA92Z14NN

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Avapena

2. Chloropyramine

3. Chloropyramine Monohydrochloride

4. Chlorpyramine

5. Halopyramine

6. N-(p-chlorobenzyl)-n-(2-pyridyl)-n',n''-dimethylethylenediamine

7. Suprastin

2.3.2 Depositor-Supplied Synonyms

1. 6170-42-9

2. Chloropyramine Hcl

3. Alergosan

4. Nilfan

5. Halopyramine Hydrochloride

6. Chlorpyramine Hydrochloride

7. N1-(4-chlorobenzyl)-n2,n2-dimethyl-n1-(pyridin-2-yl)ethane-1,2-diamine Hydrochloride

8. Allergan S Hydrochloride

9. Chlorpiramin Hydrochloride

10. Chlorpyramin Hcl

11. Chloropyribenzamine Hydrochloride

12. Fwa92z14nn

13. Mls000028842

14. Nsc-409949

15. Smr000058807

16. Dsstox_cid_28785

17. Dsstox_rid_83054

18. Dsstox_gsid_48859

19. Sinopen

20. N'-[(4-chlorophenyl)methyl]-n,n-dimethyl-n'-pyridin-2-ylethane-1,2-diamine;hydrochloride

21. 1,2-ethanediamine, N-((4-chlorophenyl)methyl)-n',n'-dimethyl-n-2-pyridinyl-, Monohydrochloride (9ci)

22. Sinopen Hydrochloride

23. Chloropyramine Monohydrochloride

24. Suprastin Hydrochloride

25. N-[(4-chlorophenyl)methyl]-n',n'-dimethyl-n-2-pyridinyl-1,2-ethanediamine

26. Sr-01000721869

27. Ncgc00016672-01

28. Ncgc00016672-04

29. Cas-6170-42-9

30. Unii-fwa92z14nn

31. Prestwick_999

32. Avapena (tn)

33. Einecs 228-216-2

34. Nsc 409949

35. N-p-chlorobenzyl-n',n'-dimethyl-n-2-pyridylethylenediamine Hydrochloride

36. Chlorpyramin Hydrochloride

37. Opera_id_1968

38. G 12144

39. Mls001077290

40. Mls002222287

41. Mls006010746

42. Schembl538104

43. Chembl550011

44. Dtxsid9048859

45. Hms1570b15

46. Pharmakon1600-01506064

47. Hy-b1305

48. Tox21_113349

49. Bdbm50015561

50. Mfcd00079009

51. Nsc409949

52. Nsc759320

53. S5670

54. Akos015961969

55. Tox21_113349_1

56. At25066

57. Ccg-213982

58. Cs-7974

59. H70c429

60. Ks-5156

61. Nsc-759320

62. Sb17058

63. N1-(4-chlorobenzyl)-n2,n2-dimethyl-n1-(pyridin-2-yl)ethane-1,2-diaminehydrochloride

64. Chloropyramine Hydrochloride [mi]

65. 1,2-ethanediamine, N-((4-chlorophenyl)methyl)-n',n'-dimethyl-n-2-pyridinyl-, Monohydrochloride

66. Ac-12197

67. Chloropyramine Hydrochloride [mart.]

68. Db-053971

69. Chloropyramine Hydrochloride [who-dd]

70. Ft-0623695

71. D07679

72. Sr-01000721869-2

73. Sr-01000721869-3

74. W-105107

75. Q27278239

76. N-p-chlorobenzyl-n',n'-dimethyl-n-(2-pyridyl)ethylenediamine

77. 2-[p-chlorobenzyl-(2-dimethylaminoethyl)amino]pyridine Hydrochloride

78. Chloropyramine Hydrochloride, Analytical Standard, For Drug Analysis

79. 1, N-[(4-chlorophenyl)methyl]-n',n'-dimethyl-n-2-pyridinyl-, Monohydrochloride

80. N-(4-chlorobenzyl)-n'n'-dimethyl-n-(2-pyridyl) Ethylenediamine Hydrochloride

81. N\'-[(4-chlorophenyl)methyl]-n,n-dimethyl-n\'-pyridin-2-ylethane-1,2-diamine,hydrochloride

82. Pyridine, 2-((p-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-, Monohydrochloride

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₁₆H₂₁Cl₂N₃
Molecular Weight	326.3 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
Exact Mass	325.1112531 g/mol
Monoisotopic Mass	325.1112531 g/mol
Topological Polar Surface Area	19.4 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	264
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Histamine H1 Antagonists

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)