Calcium Levofolinate

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

9 API Suppliers, 4 USDMF, 2 CEP/COS, 5 JDMF, 2 KDMF, 6 NDC API, 4 Listed Suppliers

PRICE INFORMATION

API Reference Price, API Exports, API Imports, FDF Imports

INTERMEDIATES

1 Suppliers

1 Suppliers

DOSSIERs // Finished Dosage Formulations

60 Dossiers, 22 FDA Orange Book, 25 Europe, 8 Canada, 2 South Africa, 3 Listed Dossiers

DRUG PRODUCT COMPOSITION

SOLUTION;INTRAVENOUS - EQ 175MG BASE/17.5ML (EQ 10MG BASE/ML) **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, SOLUTION;INTRAVENOUS - EQ 250MG BASE/25ML (EQ 10MG BASE/ML) **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, POWDER;INTRAVENOUS - EQ 50MG BASE/VIAL, POWDER;INTRAVENOUS - EQ 175MG BASE/VIAL

SOLUTION;INTRAVENOUS - EQ 175MG BASE/17.5ML (EQ 10MG BASE/ML) **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
SOLUTION;INTRAVENOUS - EQ 250MG BASE/25ML (EQ 10MG BASE/ML) **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**
POWDER;INTRAVENOUS - EQ 50MG BASE/VIAL
POWDER;INTRAVENOUS - EQ 175MG BASE/VIAL

RELATED EXCIPIENT COMPANIES

Suppliers, 12 SPI Pharma, 3 Actylis, 3 Roquette, 2 Kerry, 2 Microlex e.U, 2 Gangwal Healthcare, 2 Gangwal Chemicals, 1 Shijiazhuang Huaxu Pharmaceutical, 1 Rochem International Inc, 1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Sigachi Industries, 1 Ingredion Pharma Solutions, 1 Pfanstiehl, 1 DKSH, 1 BASF

EXCIPIENTS BY APPLICATIONS

18 Fillers, Diluents & Binders, 10 Direct Compression, 10 Chewable & Orodispersible Aids, 9 Taste Masking, 6 Parenteral, 4 Co-Processed Excipients, 3 Granulation, 3 Disintegrants & Superdisintegrants, 1 API Stability Enhancers, 1 Thickeners and Stabilizers

GLOBAL SALES INFORMATION

8 US Medicaid Prescriptions, 21 Finished Drug Prices

MARKET PLACE

4 APIs

4 APIs

ANALYTICAL SOLUTION(s)

2 EDQM Standards

2 EDQM Standards

DIGITAL CONTENT

9 News

9 News

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

15,889

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

1.00

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as:

Molecular Formula

C₂₀H₂₁CaN₇O₇

Molecular Weight

511.5 g/mol

InChI Key

KVUAALJSMIVURS-QNTKWALQSA-L

1 2D Structure

Calcium Levofolinate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

calcium;(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate

2.1.2 InChI

InChI=1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12-,13-;/m0./s1

2.1.3 InChI Key

KVUAALJSMIVURS-QNTKWALQSA-L

2.1.4 Canonical SMILES

C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]

2.1.5 Isomeric SMILES

C1[C@@H](N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Ca+2]

2.2 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₂₁CaN₇O₇
Molecular Weight	511.5 g/mol
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	7
Exact Mass	511.1128369 g/mol
Monoisotopic Mass	511.1128369 g/mol
Topological Polar Surface Area	221 A^2
Heavy Atom Count	35
Formal Charge	0
Complexity	900
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

Find Levoleucovorin Calcium manufacturers, exporters & distributors on PharmaCompass

Calcium Levofolinate

Calcium Levofolinate

Synopsis

Chemistry

APIs // Active Pharmaceutical Ingredients

9 API Suppliers

4 USDMF

2 CEP/COS

5 JDMF

2 KDMF

6 NDC API

4 Listed Suppliers

PRICE INFORMATION

API Reference Price

API Exports

API Imports

FDF Imports

INTERMEDIATES

1 Suppliers

DOSSIERs // Finished Dosage Formulations

60 Dossiers

22 FDA Orange Book

25 Europe

8 Canada

2 South Africa

3 Listed Dossiers

DRUG PRODUCT COMPOSITION

SOLUTION;INTRAVENOUS - EQ 175MG BASE/17.5ML (EQ 10MG BASE/ML) **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

SOLUTION;INTRAVENOUS - EQ 250MG BASE/25ML (EQ 10MG BASE/ML) **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

POWDER;INTRAVENOUS - EQ 50MG BASE/VIAL

POWDER;INTRAVENOUS - EQ 175MG BASE/VIAL

RELATED EXCIPIENT COMPANIES

Suppliers

12 SPI Pharma

3 Actylis

3 Roquette

2 Kerry

2 Microlex e.U

2 Gangwal Healthcare

2 Gangwal Chemicals

1 Shijiazhuang Huaxu Pharmaceutical

1 Rochem International Inc

1 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

1 Sigachi Industries

1 Ingredion Pharma Solutions

1 Pfanstiehl

1 DKSH

1 BASF

EXCIPIENTS BY APPLICATIONS

18 Fillers, Diluents & Binders

10 Direct Compression

10 Chewable & Orodispersible Aids

9 Taste Masking

6 Parenteral

4 Co-Processed Excipients

3 Granulation

3 Disintegrants & Superdisintegrants

1 API Stability Enhancers

1 Thickeners and Stabilizers

GLOBAL SALES INFORMATION

8 US Medicaid Prescriptions

21 Finished Drug Prices

MARKET PLACE

4 APIs

ANALYTICAL SOLUTION(s)

2 EDQM Standards

DIGITAL CONTENT

9 News

API SUPPLIERS

API REF. PRICE (USD / KG)

INTERMEDIATES

DOSSIERS // FDF

GLOBAL SALES (USD Million)

EXCIPIENTS

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

REF STANDARD

SERVICES

What are you looking for?

SOLUTION;INTRAVENOUS - EQ 175MG BASE/17.5ML (EQ 10MG BASE/ML) Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons

SOLUTION;INTRAVENOUS - EQ 250MG BASE/25ML (EQ 10MG BASE/ML) Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons