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Chemistry

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Also known as: 5743-28-2, Calcium l-ascorbate dihydrate, Calcium ascorbate dihydrate, Calcium ascorbate (usp), Calcium ascorbate [usp], 183e4w213w
Molecular Formula
C12H18CaO14
Molecular Weight
426.34  g/mol
InChI Key
RGJHWLDSRIHFKY-FWCDDDAWSA-L
FDA UNII
183E4W213W

Calcium Ascorbate
1 2D Structure

Calcium Ascorbate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
calcium;(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-olate;dihydrate
2.1.2 InChI
InChI=1S/2C6H8O6.Ca.2H2O/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;;;/h2*2,5,7-10H,1H2;;2*1H2/q;;+2;;/p-2/t2*2-,5+;;;/m00.../s1
2.1.3 InChI Key
RGJHWLDSRIHFKY-FWCDDDAWSA-L
2.1.4 Canonical SMILES
C(C(C1C(=C(C(=O)O1)[O-])O)O)O.C(C(C1C(=C(C(=O)O1)[O-])O)O)O.O.O.[Ca+2]
2.1.5 Isomeric SMILES
C([C@@H]([C@@H]1C(=C(C(=O)O1)[O-])O)O)O.C([C@@H]([C@@H]1C(=C(C(=O)O1)[O-])O)O)O.O.O.[Ca+2]
2.2 Other Identifiers
2.2.1 UNII
183E4W213W
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Ester C

2.3.2 Depositor-Supplied Synonyms

1. 5743-28-2

2. Calcium L-ascorbate Dihydrate

3. Calcium Ascorbate Dihydrate

4. Calcium Ascorbate (usp)

5. Calcium Ascorbate [usp]

6. 183e4w213w

7. Ester-c

8. Ins No.302

9. Calcium (r)-5-((s)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5h)-one Salt Dihydrate

10. Ins-302

11. Vitamin C (as Calcium Ascorbate)

12. Calcium Ascorbate [usan]

13. E-302

14. Unii-183e4w213w

15. Dsstox_cid_27687

16. Dsstox_rid_82503

17. Dsstox_gsid_47687

18. L-ascorbic Acid, Calcium Salt (2:1), Dihydrate

19. Calcium Ascorbate [ii]

20. Calcium Ascorbate [fcc]

21. Calcium Ascorbate [inci]

22. Chembl3184533

23. Dtxsid3047687

24. Calcium Ascorbate [vandf]

25. Calcium Ascorbate [usp-rs]

26. Tox21_303536

27. Acetic Acid, Calcium Salt, Dihydrate

28. Mfcd00149216

29. Calcium Ascorbate [ep Monograph]

30. Calcium Ascorbate [usp Monograph]

31. Ncgc00257476-01

32. E302

33. Cas-5743-28-2

34. Calcium Ascorbate Dihydrate [who-dd]

35. L(+)-ascorbicacidcalciumsaltdihydrate

36. D02293

37. Q283033

38. Calcium;(2r)-2-[(1s)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2h-furan-4-olate;dihydrate

2.4 Create Date
2011-12-26
3 Chemical and Physical Properties
Molecular Weight 426.34 g/mol
Molecular Formula C12H18CaO14
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count14
Rotatable Bond Count4
Exact Mass426.0322461 g/mol
Monoisotopic Mass426.0322461 g/mol
Topological Polar Surface Area222 Ų
Heavy Atom Count27
Formal Charge0
Complexity232
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count5
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antioxidants

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)


Vitamins

Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body. (See all compounds classified as Vitamins.)


Listed Suppliers

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01

World Dairy Expo
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World Dairy Expo
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Calcium Ascorbate

About the Company : Bajaj Healthcare Ltd. is a company established in 1993, services various Pharmaceuticals, Nutraceutical and Food industries globally with a spirit of scrupulousness. Bajaj Healt...

Bajaj Healthcare Ltd. is a company established in 1993, services various Pharmaceuticals, Nutraceutical and Food industries globally with a spirit of scrupulousness. Bajaj Healthcare Ltd. have metamorphosed into specialty company and focused on development, manufacturing and supply of Amino Acids, Nutritional Supplements and Active Pharmaceutical Ingredients (API) for Pharmaceutical, Nutraceuticals and Food industries. Bajaj healthcare Ltd. in its shot life span has gained loyalty from national and international customers and our products enjoy good fame in the overseas market.
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02

World Dairy Expo
Not Confirmed
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World Dairy Expo
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Calcium Ascorbate

About the Company : CSPC Pharmaceutical Group Limited ("CSPC") (Stock code: 1093. HK) is a leading pharmaceutical group in China. It was established in 1997. Since the very beginning, CSPC has taken ...

CSPC Pharmaceutical Group Limited ("CSPC") (Stock code: 1093. HK) is a leading pharmaceutical group in China. It was established in 1997. Since the very beginning, CSPC has taken “All for better medicine, all for a healthier world” as its corporate mission. In all aspects of development, procurement, production, and distribution, they are committed to ensuring the health of people by creating high-quality, effective, reliable, and innovative drugs that meet the needs of society.
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03

World Dairy Expo
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World Dairy Expo
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Calcium Ascorbate

About the Company : India Phosphate, established in 2007, is a leading processor, exporter, and supplier of high-quality Calcium Phosphate. Known for its purity, accuracy, and cost-effectiveness, our ...

India Phosphate, established in 2007, is a leading processor, exporter, and supplier of high-quality Calcium Phosphate. Known for its purity, accuracy, and cost-effectiveness, our products are manufactured using premium phosphoric acid and rock phosphate sourced from trusted vendors. We are committed to maintaining high standards in production while offering customization to meet client needs. With a focus on quality and affordability, we continue to serve diverse industries, ensuring reliable and efficient solutions for our customers worldwide.
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04

World Dairy Expo
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World Dairy Expo
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calcium ascorbate

About the Company : Northeast Pharmaceutical Group Co., Ltd ( NEPG ) is a large-scale comprehensive pharmaceutical enterprise in China.It is composed of three major business segments, i.e. 1. chemical...

Northeast Pharmaceutical Group Co., Ltd ( NEPG ) is a large-scale comprehensive pharmaceutical enterprise in China.It is composed of three major business segments, i.e. 1. chemical synthetic API and bio-fermentation API, 2. western medicinal preparation and micro-ecological preparation, 3. medical business distribution. NEPG produces 12 major series, mainly covering Vitamin Series, Antibiotics, Anti-AIDS, Digestives, Narcotic medicines, Cardiovascular and Cerebrovascular medicines, etc. NEPG is proud of being the first Vitamin C producer in China,
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05

World Dairy Expo
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World Dairy Expo
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Calcium Ascorbate

About the Company : Reckon Organics Private Ltd, formerly RecckonPharmachem Pvt. Ltd., specializes in manufacturing Ascorbic Acid and its derivatives. Established in 2008, the company supplies bulk dr...

Reckon Organics Private Ltd, formerly RecckonPharmachem Pvt. Ltd., specializes in manufacturing Ascorbic Acid and its derivatives. Established in 2008, the company supplies bulk drugs and intermediates to major pharmaceutical companies such as Pfizer, Abbott, and Piramal. Their state-of-the-art cGMP facility is located in Nandesari, GIDC, near Vadodara, India, focusing on quality and modern manufacturing standards.
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06

Royal DSM

Netherlands
World Dairy Expo
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Royal DSM

Netherlands
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World Dairy Expo
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Calcium Ascorbate

About the Company : Royal DSM, founded in 1902, is a global, purpose-led health, nutrition, and bioscience company that specializes in human and animal health and nutrition solutions. Its primary goal...

Royal DSM, founded in 1902, is a global, purpose-led health, nutrition, and bioscience company that specializes in human and animal health and nutrition solutions. Its primary goal is to develop health and nutrition solutions that are scientifically sound. Royal DSM's products and solutions address some of the world's most pressing issues while also adding economic, environmental and societal value to all stakeholders. More than 2.5 billion people worldwide use the company's solutions. Royal DSM and its affiliated companies employ approximately 23,000 people worldwide and generate around €10 billion in net sales per year.
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07

ShanPar

India
World Dairy Expo
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ShanPar

India
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World Dairy Expo
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Calcium Ascorbate

About the Company : SHANPAR's commitment to quality, reliability, consistency, and excellence is reflected in its esteemed clientele, which includes leading global companies. With a humble beginning 2...

SHANPAR's commitment to quality, reliability, consistency, and excellence is reflected in its esteemed clientele, which includes leading global companies. With a humble beginning 25 years ago as a manufacturer of Calcium Gluconate through electrochemistry, SHANPAR has continuously evolved. Through innovation and development, the company has expanded its portfolio to include Nutraceuticals, Mineral Fortifiers, Feed Additives, and Specialty Chemicals, establishing itself as a trusted name in the industry.
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08

World Dairy Expo
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World Dairy Expo
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calcium ascorbate

About the Company : SNEHA MEDICARE PVT LTD., one of the pioneers in API sourcing and supply in India, was established in 1985 by Shri. Kirti M Shah in the name of SNEHA CHEMICALS, which was later chan...

SNEHA MEDICARE PVT LTD., one of the pioneers in API sourcing and supply in India, was established in 1985 by Shri. Kirti M Shah in the name of SNEHA CHEMICALS, which was later changed to M/s SNEHA MEDICARE PVT LTD. in the year 2002. sneha medicare is an established brand its import and exports. We thrive to provide our customers with the highest quality material, and have established ourselves among the most eminent and trustworthy supplier of High Grade APIs and formulations.
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09

World Dairy Expo
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World Dairy Expo
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Calcium Ascorbate

About the Company : West Bengal Chemical Industries Limited, is a cGMP, ISO certified company reigning in API and Neutraceutical industries for more than half a century with its unique and uncompromis...

West Bengal Chemical Industries Limited, is a cGMP, ISO certified company reigning in API and Neutraceutical industries for more than half a century with its unique and uncompromising business vision. Mostly focused in manufacture of different mineral salts with organic acids and carbohydrates, WBCIL is reckoned to be the leader in his own domain.Ensuring to be always at your disposal, please do not hesitate to contact us over phone or write to us for additional details or queries. Our enthusiastic team is always available for your assistance and more information.
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API Reference Price

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I. D. C.,,TARA PUR, BOISAR,","city":"THANE,MAHARASHTRA","supplier":"F A PHARMA HANDELS GMBH","supplierCountry":"INDIA","foreign_port":"NA","customer":"BAJAJ HEALTHCARE LTD","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"14.5","totalValueFC":"8325.7","currency":"USD","unitRateINR":"1364.6","date":"17-Apr-2023","totalValueINR":"682318.94","totalValueInUsd":"8325.7","indian_port":"AHMEDABAD ICD","hs_no":"29362990","bill_no":"5552212","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"N - 216 & N-217, M. I. D. C.,,TARA PUR, BOISAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713551400,"product":"CALCIUM ASCORBATE -UNITED STATES","address":"401 4TH FL WINDSOR HOUSE CST RD","city":"MUMBAI, MAHARASHTRA.","supplier":"DSM NUTRITIONAL PRODUCTS ASIA PACIFIC","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. K","customer":"DSM NUTRITIONAL PRODUCTS INDIA PRIVATE LTD","customerCountry":"INDIA","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"2675.8","totalValueFC":"9612.9","currency":"INR","unitRateINR":"2675.8","date":"20-Apr-2024","totalValueINR":"802749","totalValueInUsd":"9612.9","indian_port":"Bombay Air","hs_no":"29362400","bill_no":"3109294","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"30 PASIR PANJANG ROAD #13-31, MAPLETREE BUSINESS CITY, Singapore - 117440, , Singapore Singapore","customerAddress":"401 4TH FL WINDSOR HOUSE CST RD"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1737570600,"product":"52-010-003 AZINVIT-VITAMIN C,CALCIUM ASCORBATE (100% EOU) 52-010-003 AZINVIT-VITAMIN C,CALCIUM ASCORBATE","address":"1\/486 -J, AMBUNAD,,MALAYIDAMTHURUT","city":"ALUVA,KERALA","supplier":"AZINGRO NV","supplierCountry":"CHINA","foreign_port":"BRUSSELS","customer":"AKAY NATURAL INGREDIENTS PRIVATE LTD","customerCountry":"INDIA","quantity":"250.00","actualQuantity":"250","unit":"KGS","unitRateFc":"11.6","totalValueFC":"2936.7","currency":"USD","unitRateINR":"1012.9","date":"23-Jan-2025","totalValueINR":"253229.64","totalValueInUsd":"2936.7","indian_port":"Cochin Air","hs_no":"29362990","bill_no":"7948672","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BRUSSELS","supplierAddress":"WIEKEVORSTSESTEENWEG 38 2220 HEIST- OP-DEN-BERG SDNF","customerAddress":"1\/486 -J, AMBUNAD,,MALAYIDAMTHURUT"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q2","strtotime":1751049000,"product":"52-010-003 AZINVIT-VITAMIN C,CALCIUM ASCORBATE (100% EOU) 52-010-003 AZINVIT-VITAMIN C,CALCIUM ASCORBATE (100% EOU)","address":"1\/486 -J, AMBUNAD,,MALAYIDAMTHURUT","city":"ALUVA,KERALA","supplier":"AZINGRO NV","supplierCountry":"CHINA","foreign_port":"BRUSSELS","customer":"AKAY NATURAL INGREDIENTS PRIVATE LTD","customerCountry":"INDIA","quantity":"250.00","actualQuantity":"250","unit":"KGS","unitRateFc":"11.9","totalValueFC":"3034.7","currency":"USD","unitRateINR":"1043","date":"28-Jun-2025","totalValueINR":"260758.75","totalValueInUsd":"3034.7","indian_port":"Cochin Air","hs_no":"29362990","bill_no":"2935862","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BRUSSELS","supplierAddress":"WIEKEVORSTSESTEENWEG 38 2220 HEIST OP-DEN-BERG Belgium SDNF Belgium","customerAddress":"1\/486 -J, AMBUNAD,,MALAYIDAMTHURUT"}]
15-Mar-2022
28-Jun-2025
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ABOUT THIS PAGE

Looking for 5743-27-1 / Calcium Ascorbate API manufacturers, exporters & distributors?

Calcium Ascorbate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Calcium Ascorbate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Calcium Ascorbate manufacturer or Calcium Ascorbate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Calcium Ascorbate manufacturer or Calcium Ascorbate supplier.

PharmaCompass also assists you with knowing the Calcium Ascorbate API Price utilized in the formulation of products. Calcium Ascorbate API Price is not always fixed or binding as the Calcium Ascorbate Price is obtained through a variety of data sources. The Calcium Ascorbate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Calcium Ascorbate

Synonyms

5743-28-2, Calcium l-ascorbate dihydrate, Calcium ascorbate dihydrate, Calcium ascorbate (usp), Calcium ascorbate [usp], 183e4w213w

Cas Number

5743-27-1

Unique Ingredient Identifier (UNII)

183E4W213W

Calcium Ascorbate Manufacturers

A Calcium Ascorbate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Calcium Ascorbate, including repackagers and relabelers. The FDA regulates Calcium Ascorbate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Calcium Ascorbate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Calcium Ascorbate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Calcium Ascorbate Suppliers

A Calcium Ascorbate supplier is an individual or a company that provides Calcium Ascorbate active pharmaceutical ingredient (API) or Calcium Ascorbate finished formulations upon request. The Calcium Ascorbate suppliers may include Calcium Ascorbate API manufacturers, exporters, distributors and traders.

click here to find a list of Calcium Ascorbate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Calcium Ascorbate CEP

A Calcium Ascorbate CEP of the European Pharmacopoeia monograph is often referred to as a Calcium Ascorbate Certificate of Suitability (COS). The purpose of a Calcium Ascorbate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Calcium Ascorbate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Calcium Ascorbate to their clients by showing that a Calcium Ascorbate CEP has been issued for it. The manufacturer submits a Calcium Ascorbate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Calcium Ascorbate CEP holder for the record. Additionally, the data presented in the Calcium Ascorbate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Calcium Ascorbate DMF.

A Calcium Ascorbate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Calcium Ascorbate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Calcium Ascorbate suppliers with CEP (COS) on PharmaCompass.

Calcium Ascorbate GMP

Calcium Ascorbate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Calcium Ascorbate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Calcium Ascorbate GMP manufacturer or Calcium Ascorbate GMP API supplier for your needs.

Calcium Ascorbate CoA

A Calcium Ascorbate CoA (Certificate of Analysis) is a formal document that attests to Calcium Ascorbate's compliance with Calcium Ascorbate specifications and serves as a tool for batch-level quality control.

Calcium Ascorbate CoA mostly includes findings from lab analyses of a specific batch. For each Calcium Ascorbate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Calcium Ascorbate may be tested according to a variety of international standards, such as European Pharmacopoeia (Calcium Ascorbate EP), Calcium Ascorbate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Calcium Ascorbate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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