Find Caffeine Citrate manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

API REF. PRICE (USD/KG)

MARKET PLACE

0INTERMEDIATES

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

2 RELATED EXCIPIENT COMPANIES

2EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 69-22-7, Caffeine, citrated, Cafcit, Caffeine citrated, Citrated caffeine, 1,2,3-propanetricarboxylic acid, 2-hydroxy-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1h-purine-2,6-dione
Molecular Formula
C14H18N4O9
Molecular Weight
386.31  g/mol
InChI Key
RCQXSQPPHJPGOF-UHFFFAOYSA-N
FDA UNII
U26EO4675Q

Caffeine Citrate
Caffeine Citrate is commercial citrate of caffeine, though not a definite salt. It is the alkaloid caffeine, with a portion of adherent citric acid, as indicated by its pharmacopoeial name (citrated caffeine). Its general action and uses are the same as those given under caffeine. Caffeine citrate is used chiefly as a remedy for the idiopathic headache (migraine). This salt is very soluble in water, and is assimilated much more readily than pure caffeine when taken into the stomach. (NCI04)
1 2D Structure

Caffeine Citrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-hydroxypropane-1,2,3-tricarboxylic acid;1,3,7-trimethylpurine-2,6-dione
2.1.2 InChI
InChI=1S/C8H10N4O2.C6H8O7/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2;7-3(8)1-6(13,5(11)12)2-4(9)10/h4H,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
2.1.3 InChI Key
RCQXSQPPHJPGOF-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN1C=NC2=C1C(=O)N(C(=O)N2C)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
2.2 Other Identifiers
2.2.1 UNII
U26EO4675Q
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cafcit

2.3.2 Depositor-Supplied Synonyms

1. 69-22-7

2. Caffeine, Citrated

3. Cafcit

4. Caffeine Citrated

5. Citrated Caffeine

6. 1,2,3-propanetricarboxylic Acid, 2-hydroxy-, Mixt. With 3,7-dihydro-1,3,7-trimethyl-1h-purine-2,6-dione

7. Caffeine Mixture With Citric Acid

8. U26eo4675q

9. 2-hydroxypropane-1,2,3-tricarboxylic Acid;1,3,7-trimethylpurine-2,6-dione

10. Ncgc00015208-09

11. Caffeina Citrate

12. Citrated Caffein

13. Dsstox_cid_26938

14. Dsstox_rid_82023

15. Dsstox_gsid_46938

16. Caffeine Citrate (1:1)

17. Cas-69-22-7

18. Caffeinecitrated

19. Caffeine, Citrated [nf]

20. Citric Acid, Compd. With Caffeine (1:1)

21. Unii-u26eo4675q

22. Cafcit (tn)

23. Caffeine Citrate (usp)

24. Caffeine-citric Acid 1/1

25. Schembl452067

26. Chembl1200569

27. Dtxsid5046938

28. Caffeine Citrate [mart.]

29. Citrated Caffeine [vandf]

30. Caffeine Citrate [who-dd]

31. Caffeine Citrate [ema Epar]

32. Nsc63248

33. Tox21_110099

34. Nsc-63248

35. Akos030254796

36. Caffeine Citrate [orange Book]

37. Tox21_110099_1

38. Caffeine Citrate [usp Impurity]

39. Ncgc00015208-19

40. 1,2,3-propanetricarboxylic Acid,2-hydroxy-,compounds,mixt. With 3,7-dihydro-1,3,7-trimethyl-1h-purine-2,6- Dione

41. Db-055239

42. Ft-0623368

43. Caffeine Mixture With Citric Acid [mi]

44. D07603

45. Q2974480

46. 3,7-dihydro-1,3,7-trimethyl-1h-purine-2,6-dione Citrate

47. 1,3,7-trimethyl-1h-purine-2,6(3h,7h)-dione 2-hydroxypropane-1,2,3-tricarboxylate

48. 1h-purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-, 2-hydroxypropane-1,2,3-tricarboxylate

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 386.31 g/mol
Molecular Formula C14H18N4O9
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Exact Mass386.10737816 g/mol
Monoisotopic Mass386.10737816 g/mol
Topological Polar Surface Area191 Ų
Heavy Atom Count27
Formal Charge0
Complexity520
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameCaffeine citrate
PubMed HealthCaffeine Citrate
Drug ClassesCNS Stimulant, Stimulant, Respiratory
Drug LabelBoth Caffeine Citrate Injection, USP for intravenous administration and Caffeine Citrate Oral Solution, USP are clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solutions adjusted to pH 4.7. Each mL contains 20 mg caffeine citrate...
Active IngredientCaffeine citrate
Dosage FormSolution
RouteIntravenous; Oral
Strengtheq 30mg base/3ml (eq 10mg base/ml)
Market StatusPrescription
CompanyExela Pharma Science; Exela Pharma Scs; Fresenius Kabi Usa; Luitpold; Sagent Pharms; Sun Pharma Global

2 of 2  
Drug NameCaffeine citrate
PubMed HealthCaffeine Citrate
Drug ClassesCNS Stimulant, Stimulant, Respiratory
Drug LabelBoth Caffeine Citrate Injection, USP for intravenous administration and Caffeine Citrate Oral Solution, USP are clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solutions adjusted to pH 4.7. Each mL contains 20 mg caffeine citrate...
Active IngredientCaffeine citrate
Dosage FormSolution
RouteIntravenous; Oral
Strengtheq 30mg base/3ml (eq 10mg base/ml)
Market StatusPrescription
CompanyExela Pharma Science; Exela Pharma Scs; Fresenius Kabi Usa; Luitpold; Sagent Pharms; Sun Pharma Global

4.2 Drug Indication

Treatment of primary apnoea of premature newborns.


5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Central Nervous System Stimulants

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Central Nervous System Stimulation [PE]; Methylxanthine [EPC]; Xanthines [CS]; Central Nervous System Stimulant [EPC]
5.3 ATC Code

N06BC01


API SUPPLIERS

read-more
read-more
Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

read-more
read-more
[{"dataSource":"API Export","activeIngredients":"CAFFEINE CITRATE","year":"2021","qtr":"Q1","strtotime":1615746600,"product":"CITRATED CAFFEINE (CAFFEINE CITRATE NF)","address":"MAHAKALI ROAD","city":"MUMBAI ,MAHARASHTRA","supplier":"INGA PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"HONG KONG","customer":"JEAN MARIE PHARMACAL ","customerCountry":"HONG KONG","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"367.2","totalValueFC":"1821","currency":"USD","unitRateINR":26514.799999999999,"date":"15-Mar-2021","totalValueINR":"132574","totalValueInUsd":"1821","indian_port":"Madras-EPZ\/SEZ","hs_no":"29393000","bill_no":"4003979","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"HONG KONG","selfForZScoreResived":"Pharma Grade","supplierPort":"Madras-EPZ\/SEZ","supplierAddress":"MAHAKALI ROAD, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"CAFFEINE CITRATE","year":"2021","qtr":"Q2","strtotime":1620671400,"product":"CITRATED CAFFEINE ( CAFFEINE CITRATE NF)","address":"MAHAKALI ROAD","city":"MUMBAI ,MAHARASHTRA","supplier":"INGA PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"TO THE ORDER OF CHEIRON PHARMA GMBH","customerCountry":"TURKEY","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"926.8","totalValueFC":"1848.5","currency":"USD","unitRateINR":67702.5,"date":"11-May-2021","totalValueINR":"135405","totalValueInUsd":"1848.5","indian_port":"Madras-EPZ\/SEZ","hs_no":"29393000","bill_no":"4007046","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"Madras-EPZ\/SEZ","supplierAddress":"MAHAKALI ROAD, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1627497000,"product":"CAFFEINE CITRATE","address":"N - 216 & N-217, M. I. D. C.,TARAPUR, BOISAR,","city":"THANE, MAHARASHTRA.","supplier":"BAJAJ HEALTHCARE","supplierCountry":"INDIA","foreign_port":"ST LOUIS","customer":"TO ORDER","customerCountry":"UNITED STATES","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"19.7","totalValueFC":"19036.5","currency":"USD","unitRateINR":1418.7249999999999,"date":"29-Jul-2021","totalValueINR":"1418725","totalValueInUsd":"19036.5","indian_port":"JNPT","hs_no":"29393000","bill_no":"3461854","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"N - 216 & N-217, M. I. D. C.,TARAPUR, BOISAR,, THANE, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1646591400,"product":"CITRATED CAFFEINE(CAFFEINE CITRATE NF)","address":"MAHAKALI ROAD","city":"MUMBAI ,MAHARASHTRA","supplier":"INGA PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"MOSCOW DOMODEDOVO","customer":"TO THE ORDER OF MIR - PHARM LTD","customerCountry":"RUSSIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"1875.2","totalValueFC":"3688","currency":"USD","unitRateINR":140547.5,"date":"07-Mar-2022","totalValueINR":"281095","totalValueInUsd":"3688","indian_port":"Madras-EPZ\/SEZ","hs_no":"29393000","bill_no":"4003567","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Madras-EPZ\/SEZ","supplierAddress":"MAHAKALI ROAD, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1652034600,"product":"CAFFEINE CITRATE BPC","address":"N - 216 & N-217, M. I. D. C.,,TARA PUR, BOISAR,","city":"THANE,MAHARASHTRA","supplier":"BAJAJ HEALTHCARE","supplierCountry":"INDIA","foreign_port":"SYDNEY","customer":"TO ORDER","customerCountry":"AUSTRALIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"1100","totalValueFC":"854","currency":"USD","unitRateINR":66000,"date":"09-May-2022","totalValueINR":"66000","totalValueInUsd":"854","indian_port":"BOMBAY AIR","hs_no":"29393000","bill_no":"1265297","productDescription":"API","marketType":"REGULATED MARKET","country":"AUSTRALIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"N - 216 & N-217, M. I. D. C.,,TARA PUR, BOISAR,, THANE,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1654194600,"product":"CITRATED CAFFEINE (CAFFEINE CITRATE NF)","address":"MAHAKALI ROAD","city":"MUMBAI ,MAHARASHTRA","supplier":"INGA PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"AMSTERDAM","customer":"TO THE ORDER OF","customerCountry":"NETHERLANDS","quantity":"300.00","actualQuantity":"300","unit":"KGS","unitRateFc":"82.6","totalValueFC":"24398.1","currency":"USD","unitRateINR":6344.7533333333331,"date":"03-Jun-2022","totalValueINR":"1903426","totalValueInUsd":"24398.1","indian_port":"Madras-EPZ\/SEZ","hs_no":"29393000","bill_no":"4008371","productDescription":"API","marketType":"REGULATED MARKET","country":"NETHERLANDS","selfForZScoreResived":"Pharma Grade","supplierPort":"Madras-EPZ\/SEZ","supplierAddress":"MAHAKALI ROAD, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670178600,"product":"CAFFEINE CITRATE","address":"N - 216 & N-217, M. I. D. C.,,TARA PUR, BOISAR,","city":"THANE,MAHARASHTRA","supplier":"BAJAJ HEALTHCARE","supplierCountry":"INDIA","foreign_port":"TEL AVIV YAFO","customer":"TO ORDER","customerCountry":"ISRAEL","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"60","totalValueFC":"946.5","currency":"USD","unitRateINR":3120,"date":"05-Dec-2022","totalValueINR":"78000","totalValueInUsd":"946.5","indian_port":"BOMBAY AIR","hs_no":"29393000","bill_no":"5944164","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ISRAEL","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"N - 216 & N-217, M. I. D. C.,,TARA PUR, BOISAR,, THANE,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1681065000,"product":"CITRATED CAFFENINE NF (CAFFEINE CITRATE)","address":"MAHAKALI ROAD","city":"MUMBAI ,MAHARASHTRA","supplier":"INGA PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"SANTA CRUZ","customer":"TO THE ORDER OF MERQUIMIA BOLIVIA SRL","customerCountry":"BOLIVIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"1411.7","totalValueFC":"1397","currency":"USD","unitRateINR":114488,"date":"10-Apr-2023","totalValueINR":"114488","totalValueInUsd":"1397","indian_port":"Madras-EPZ\/SEZ","hs_no":"29393000","bill_no":"4005539","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BOLIVIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Madras-EPZ\/SEZ","supplierAddress":"MAHAKALI ROAD, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1693420200,"product":"CAFFEINE CITRATE","address":"N - 216 & N-217 M. I. D. C.TARA PUR BOISAR","city":"THANE","supplier":"BAJAJ HEALTHCARE","supplierCountry":"INDIA","foreign_port":"BRATISLAVA","customer":"Z TO ORDER AND NA","customerCountry":"SLOVAKIA","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"40","totalValueFC":"946.5","currency":"USD","unitRateINR":3136.02864,"date":"31-Aug-2023","totalValueINR":"78400.716","totalValueInUsd":"946.5","indian_port":"BOMBAY AIR","hs_no":"29393000","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"SLOVAKIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"N - 216 & N-217 M. I. D. C.TARA PUR BOISAR, THANE","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1703874600,"product":"CAFFEINE CITRATE I.P.","address":"SHOP NO.16,GOKUL REGENCY II,","city":"MUMBAI, MAHARASHTRA","supplier":"JAYA IMPEX","supplierCountry":"INDIA","foreign_port":"ACCRA","customer":"OMER INVESTMENT LTD","customerCountry":"GHANA","quantity":"10.00","actualQuantity":"10","unit":"KGS","unitRateFc":"30.8","totalValueFC":"84.1","currency":"USD","unitRateINR":700,"date":"30-Dec-2023","totalValueINR":"7000","totalValueInUsd":"84.1","indian_port":"Bombay Air","hs_no":"29393000","bill_no":"6433794","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"GHANA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"SHOP NO.16,GOKUL REGENCY II,, MUMBAI, MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1704738600,"product":"CAFFEINE CITRATE","address":"N - 216 N-217, M. I. D. C.,","city":"THANE, MAHARASHTRA.","supplier":"BAJAJ HEALTHCARE","supplierCountry":"INDIA","foreign_port":"ST LOUIS","customer":"TO ORDER","customerCountry":"UNITED STATES","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"15","totalValueFC":"14889.6","currency":"USD","unitRateINR":1237.5,"date":"09-Jan-2024","totalValueINR":"1237500","totalValueInUsd":"14889.6","indian_port":"JNPT","hs_no":"29393000","bill_no":"6620504","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"N - 216 N-217, M. I. D. C.,, THANE, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725993000,"product":"CAFFEINE CITRATE","address":"N - 216 N-217, M. I. D. C.,","city":"THANE, MAHARASHTRA.","supplier":"BAJAJ HEALTHCARE","supplierCountry":"INDIA","foreign_port":"ST LOUIS","customer":"CREATIVE COMPOUNDS LLC","customerCountry":"UNITED STATES","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"15","totalValueFC":"29766.9","currency":"USD","unitRateINR":1247.25,"date":"11-Sep-2024","totalValueINR":"2494500","totalValueInUsd":"29766.9","indian_port":"JNPT","hs_no":"29393000","bill_no":"3927155","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"N - 216 N-217, M. I. D. C.,, THANE, MAHARASHTRA.","customerAddress":""}]
15-Mar-2021
11-Sep-2024
KGS
overview
Loading...

Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

Upgrade, download data, analyse, strategize, subscribe with us contact

Related Excipient Companies

Upload your portfolio for free, ask us

Digital Content read-more

Create Content with PharmaCompass, ask us

NEWS #PharmaBuzz

read-more
read-more

Global Sales Information

Do you need Business Intel? Ask us

Market Place

Do you need sourcing support? Ask us