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Chemistry

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Also known as: 1025097-10-2, Act-179811, 2oea2un10y, 1-cyclopropyl-6-fluoro-7-[4-[[2-fluoro-4-[(5r)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]-4-hydroxypiperidin-1-yl]-4-oxoquinoline-3-carboxylic acid, 1-cyclopropyl-6-fluoro-7-(4-((2-fluoro-4-((r)-5-hydroxymethyl-2-oxooxazolidin-3-yl)phenoxy)methyl)-4-hydroxypiperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, Cadazolid [inn]
Molecular Formula
C29H29F2N3O8
Molecular Weight
585.6  g/mol
InChI Key
XWFCFMXQTBGXQW-GOSISDBHSA-N
FDA UNII
2OEA2UN10Y

Cadazolid
Cadazolid is an oxazolidinone-type antibiotic, with activity against gram-positive bacteria, including Clostridium difficile. Although the exact mode of action through which cadazolid exerts its effect has yet to be fully elucidated, upon administration, this agent inhibits bacterial protein synthesis and leads to bacterial cell death.
1 2D Structure

Cadazolid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-cyclopropyl-6-fluoro-7-[4-[[2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]-4-hydroxypiperidin-1-yl]-4-oxoquinoline-3-carboxylic acid
2.1.2 InChI
InChI=1S/C29H29F2N3O8/c30-21-10-19-23(33(16-1-2-16)13-20(26(19)36)27(37)38)11-24(21)32-7-5-29(40,6-8-32)15-41-25-4-3-17(9-22(25)31)34-12-18(14-35)42-28(34)39/h3-4,9-11,13,16,18,35,40H,1-2,5-8,12,14-15H2,(H,37,38)/t18-/m1/s1
2.1.3 InChI Key
XWFCFMXQTBGXQW-GOSISDBHSA-N
2.1.4 Canonical SMILES
C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCC(CC4)(COC5=C(C=C(C=C5)N6CC(OC6=O)CO)F)O)F)C(=O)O
2.1.5 Isomeric SMILES
C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCC(CC4)(COC5=C(C=C(C=C5)N6C[C@@H](OC6=O)CO)F)O)F)C(=O)O
2.2 Other Identifiers
2.2.1 UNII
2OEA2UN10Y
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 1025097-10-2

2. Act-179811

3. 2oea2un10y

4. 1-cyclopropyl-6-fluoro-7-[4-[[2-fluoro-4-[(5r)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]-4-hydroxypiperidin-1-yl]-4-oxoquinoline-3-carboxylic Acid

5. 1-cyclopropyl-6-fluoro-7-(4-((2-fluoro-4-((r)-5-hydroxymethyl-2-oxooxazolidin-3-yl)phenoxy)methyl)-4-hydroxypiperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

6. Cadazolid [inn]

7. Cadazolid [usan:inn]

8. Unii-2oea2un10y

9. Cadazolid (usan/inn)

10. Cadazolid [usan]

11. Cadazolid [who-dd]

12. Schembl541618

13. Cadazolid (act-179811)

14. Chembl3707376

15. Gtpl10767

16. Dtxsid10145234

17. Bcp20623

18. Ex-a1438

19. Act179811

20. Cs-6972

21. Db11847

22. Ac-35473

23. Hy-100436

24. J3.437.086i

25. D11207

26. A900061

27. Q15408418

28. (r)-1-cyclopropyl-6-fluoro-7-(4-((2-fluoro-4-(5-(hydroxymethyl)-2-oxooxazolidin-3-yl)phenoxy)methyl)-4-hydroxypiperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

29. 3-quinolinecarboxylic Acid, 1-cyclopropyl-6-fluoro-7-(4-((2-fluoro-4-((5r)-5-(hydroxymethyl)-2-oxo-3-oxazolidinyl)phenoxy)methyl)-4-hydroxy-1-piperidinyl)-1,4-dihydro-4-oxo-

30. Jjh

2.4 Create Date
2009-11-02
3 Chemical and Physical Properties
Molecular Weight 585.6 g/mol
Molecular Formula C29H29F2N3O8
XLogP33.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count8
Exact Mass585.19227122 g/mol
Monoisotopic Mass585.19227122 g/mol
Topological Polar Surface Area140 Ų
Heavy Atom Count42
Formal Charge0
Complexity1100
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Treatment of Clostridium difficile infection


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Looking for 1025097-10-2 / Cadazolid API manufacturers, exporters & distributors?

Cadazolid manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Cadazolid API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cadazolid manufacturer or Cadazolid supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cadazolid manufacturer or Cadazolid supplier.

PharmaCompass also assists you with knowing the Cadazolid API Price utilized in the formulation of products. Cadazolid API Price is not always fixed or binding as the Cadazolid Price is obtained through a variety of data sources. The Cadazolid Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Cadazolid

Synonyms

1025097-10-2, Act-179811, 2oea2un10y, 1-cyclopropyl-6-fluoro-7-[4-[[2-fluoro-4-[(5r)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]-4-hydroxypiperidin-1-yl]-4-oxoquinoline-3-carboxylic acid, 1-cyclopropyl-6-fluoro-7-(4-((2-fluoro-4-((r)-5-hydroxymethyl-2-oxooxazolidin-3-yl)phenoxy)methyl)-4-hydroxypiperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, Cadazolid [inn]

Cas Number

1025097-10-2

Unique Ingredient Identifier (UNII)

2OEA2UN10Y

About Cadazolid

Cadazolid is an oxazolidinone-type antibiotic, with activity against gram-positive bacteria, including Clostridium difficile. Although the exact mode of action through which cadazolid exerts its effect has yet to be fully elucidated, upon administration, this agent inhibits bacterial protein synthesis and leads to bacterial cell death.

Cadazolid Manufacturers

A Cadazolid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cadazolid, including repackagers and relabelers. The FDA regulates Cadazolid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cadazolid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Cadazolid Suppliers

A Cadazolid supplier is an individual or a company that provides Cadazolid active pharmaceutical ingredient (API) or Cadazolid finished formulations upon request. The Cadazolid suppliers may include Cadazolid API manufacturers, exporters, distributors and traders.

Cadazolid GMP

Cadazolid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cadazolid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cadazolid GMP manufacturer or Cadazolid GMP API supplier for your needs.

Cadazolid CoA

A Cadazolid CoA (Certificate of Analysis) is a formal document that attests to Cadazolid's compliance with Cadazolid specifications and serves as a tool for batch-level quality control.

Cadazolid CoA mostly includes findings from lab analyses of a specific batch. For each Cadazolid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cadazolid may be tested according to a variety of international standards, such as European Pharmacopoeia (Cadazolid EP), Cadazolid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cadazolid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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