Benzydamine

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Also known as: 132-69-4, Benzydamine hcl, Benzidamine hydrochloride, Benzindamine hydrochloride, Tantum, Benzydamine (hydrochloride)

Molecular Formula

C₁₉H₂₄ClN₃O

Molecular Weight

345.9 g/mol

InChI Key

HNNIWKQLJSNAEQ-UHFFFAOYSA-N

FDA UNII

K2GI407R4Q

A benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. It is used to reduce post-surgical and post-traumatic pain and edema and to promote healing. It is also used topically in treatment of RHEUMATIC DISEASES and INFLAMMATION of the mouth and throat.

1 2D Structure

Benzydamine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine;hydrochloride

2.1.2 InChI

InChI=1S/C19H23N3O.ClH/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16;/h3-7,9-12H,8,13-15H2,1-2H3;1H

2.1.3 InChI Key

HNNIWKQLJSNAEQ-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN(C)CCCOC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3.Cl

2.2 Other Identifiers

2.2.1 UNII

K2GI407R4Q

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Benzidamine

2. Benzindamine

3. Benzydamine

4. Benzydamine Monohydrochloride

5. Difflam

6. Hydrochloride, Benzydamine

7. Lonol

8. Monohydrochloride, Benzydamine

9. Novo Benzydamine

10. Novo-benzydamine

11. Opalgyne

12. Pms Benzydamine

13. Pms-benzydamine

14. Ratio Benzydamine

15. Ratio-benzydamine

16. Rosalgin

17. Sun Benz

18. Sun-benz

19. Tantum

20. Tantum Topico

2.3.2 Depositor-Supplied Synonyms

1. 132-69-4

2. Benzydamine Hcl

3. Benzidamine Hydrochloride

4. Benzindamine Hydrochloride

5. Tantum

6. Benzydamine (hydrochloride)

7. Af-864

8. Nsc-759276

9. 132-69-4 (hcl)

10. K2gi407r4q

11. Benalgin

12. {3-[(1-benzyl-1h-indazol-3-yl)oxy]propyl}dimethylamine Hydrochloride

13. 1-benzyl-3-(3-(dimethylamino)propoxy)-1h-indazole Monohydrochloride

14. 3-((1-benzyl-1h-indazol-3-yl)oxy)-n,n-dimethylpropan-1-amine Hydrochloride

15. 1-propanamine, N,n-dimethyl-3-((1-(phenylmethyl)-1h-indazol-3-yl)oxy)-, Monohydrochloride

16. Benzidan

17. Benzyrin

18. Difflam

19. Dorinamin

20. Enzamin

21. Epirotin

22. Flogaton

23. Imotryl

24. Oxinazin

25. Ririlim

26. Riripen

27. Salyzoron

28. Tamas

29. Verax

30. 1-benzyl-3-(3-(dimethylamino)propoxy)-1h-indazole Hydrochloride

31. 1-benzyl-3-(3-[dimethylamino]propoxy)-1h-indazole Hydrochloride

32. Dsstox_cid_25293

33. Dsstox_rid_80786

34. Dsstox_gsid_45293

35. 1-benzyl-3-[3-(dimethylamino)propoxy]-1h-indazole Hydrochloride

36. 3-(1-benzylindazol-3-yl)oxy-n,n-dimethylpropan-1-amine;hydrochloride

37. Smr000544402

38. Ncgc00016397-01

39. Cas-132-69-4

40. Einecs 205-076-0

41. Af 864

42. Af864

43. Benzydamine Hydrochloride [usan:jan]

44. Unii-k2gi407r4q

45. Sr-01000799149

46. Benzydamine, Hcl

47. Prestwick_403

48. Tantum (tn)

49. 1-benzyl-3-gamma-dimethylaminopropoxy-1h-indazole Hydrochloride

50. 1-propanamine, N,n-dimethyl-3-((1-(phenylmethyl)-1h-indazol-3-yl)oxy)-, Hydrochloride

51. Schembl42644

52. Benzydaminehydrochloride

53. Mls001216204

54. Mls001306431

55. Mls001333107

56. Mls001333108

57. Mls002222210

58. Not Available;benzydamine Hcl

59. Benzydamine-[d6] Hydrochloride

60. Chembl1528134

61. Dtxsid1045293

62. Chebi:31266

63. Hms1568l16

64. Pharmakon1600-01505975

65. Bcp12133

66. Tox21_110420

67. Hy-30235a

68. Mfcd00078957

69. Nsc759276

70. S4165

71. Benzydamine Hydrochloride (jan/usan)

72. Benzydamine Hydrochloride [mi]

73. 1h-indazole, 1-benzyl-3-(3-(dimethylamino)propoxy)-, Monohydrochloride

74. 3-((1-benzyl-1h-indazol-3-yl)oxy)-n,n-dimethylpropylamine Monohydrochloride

75. Akos015994635

76. Tox21_110420_1

77. Ac-6791

78. Benzydamine Hydrochloride [jan]

79. Ccg-213582

80. Cs-4463

81. Hs-1002

82. Nsc 759276

83. Benzydamine Hydrochloride [usan]

84. Benzydamine Hydrochloride [mart.]

85. Ncgc00016397-04

86. Benzydamine Hydrochloride [who-dd]

87. 1-benzyl-3-hydroxy-1h-indazolesodiumsalt

88. B3751

89. Ft-0662621

90. Sw196646-3

91. Benzydamine Hydrochloride, Analytical Standard

92. A14562

93. Benzydamine Hydrochloride [ep Monograph]

94. D01410

95. H10439

96. A854848

97. J-006209

98. Sr-01000799149-4

99. Q27281858

100. 1-benzyl-3-(3-(dimethylamino) Propoxy)-1h Indozale Hydrochloride

101. 3-(1-benzyl-1h-indazol-3-yloxy)-n,n-dimethylpropan-1-amine Hydrochloride

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₂₄ClN₃O
Molecular Weight	345.9 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	7
Exact Mass	345.1607901 g/mol
Monoisotopic Mass	345.1607901 g/mol
Topological Polar Surface Area	30.3 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	344
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2