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    Chemistry

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    Also known as: 863031-24-7, Azilsartan (medoxomil monopotassium), Azilsartan kamedoxomil, Azilsartan medoxomil monopotassium, Bcp11249, Sb19561
    Molecular Formula
    C30H23KN4O8
    Molecular Weight
    606.6  g/mol
    InChI Key
    IHWFKDWIUSZLCJ-UHFFFAOYSA-M
    Azilsartan
    1 2D Structure

    Azilsartan

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    potassium;(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-1-oxa-4-aza-2-azanidacyclopent-3-en-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
    2.1.2 InChI
    InChI=1S/C30H24N4O8.K/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26;/h4-14H,3,15-16H2,1-2H3,(H,32,33,36);/q;+1/p-1
    2.1.3 InChI Key
    IHWFKDWIUSZLCJ-UHFFFAOYSA-M
    2.1.4 Canonical SMILES
    CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)O[N-]5)C(=O)OCC6=C(OC(=O)O6)C.[K+]
    2.2 Synonyms
    2.2.1 Depositor-Supplied Synonyms

    1. 863031-24-7

    2. Azilsartan (medoxomil Monopotassium)

    3. Azilsartan Kamedoxomil

    4. Azilsartan Medoxomil Monopotassium

    5. Bcp11249

    6. Sb19561

    7. Hy-17458

    8. Potassium;(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-3-[[4-[2-(5-oxo-1-oxa-4-aza-2-azanidacyclopent-3-en-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate

    9. Potassium 3-(4'-((2-ethoxy-7-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)-1h-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-yl)-5-oxo-5h-1,2,4-oxadiazol-2-ide

    2.3 Create Date
    2015-09-21
    3 Chemical and Physical Properties
    Molecular Weight 606.6 g/mol
    Molecular Formula C30H23KN4O8
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count10
    Rotatable Bond Count10
    Exact Mass606.11529519 g/mol
    Monoisotopic Mass606.11529519 g/mol
    Topological Polar Surface Area129 Ų
    Heavy Atom Count43
    Formal Charge0
    Complexity1110
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 FDA Pharmacological Classification
    4.1.1 Pharmacological Classes
    Angiotensin 2 Type 1 Receptor Antagonists [MoA]; Decreased Blood Pressure [PE]; Angiotensin 2 Receptor Blocker [EPC]

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    05-Feb-2021
    06-Mar-2025
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    Azilsartan manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Azilsartan API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Azilsartan manufacturer or Azilsartan supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Azilsartan manufacturer or Azilsartan supplier.

    PharmaCompass also assists you with knowing the Azilsartan API Price utilized in the formulation of products. Azilsartan API Price is not always fixed or binding as the Azilsartan Price is obtained through a variety of data sources. The Azilsartan Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Azilsartan

    Synonyms

    863031-24-7, Azilsartan (medoxomil monopotassium), Azilsartan kamedoxomil, Azilsartan medoxomil monopotassium, Bcp11249, Sb19561

    Cas Number

    863031-24-7

    Azilsartan Medoxomil Manufacturers

    A Azilsartan Medoxomil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Azilsartan Medoxomil, including repackagers and relabelers. The FDA regulates Azilsartan Medoxomil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Azilsartan Medoxomil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Azilsartan Medoxomil manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Azilsartan Medoxomil Suppliers

    A Azilsartan Medoxomil supplier is an individual or a company that provides Azilsartan Medoxomil active pharmaceutical ingredient (API) or Azilsartan Medoxomil finished formulations upon request. The Azilsartan Medoxomil suppliers may include Azilsartan Medoxomil API manufacturers, exporters, distributors and traders.

    click here to find a list of Azilsartan Medoxomil suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Azilsartan Medoxomil USDMF

    A Azilsartan Medoxomil DMF (Drug Master File) is a document detailing the whole manufacturing process of Azilsartan Medoxomil active pharmaceutical ingredient (API) in detail. Different forms of Azilsartan Medoxomil DMFs exist exist since differing nations have different regulations, such as Azilsartan Medoxomil USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Azilsartan Medoxomil DMF submitted to regulatory agencies in the US is known as a USDMF. Azilsartan Medoxomil USDMF includes data on Azilsartan Medoxomil's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Azilsartan Medoxomil USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Azilsartan Medoxomil suppliers with USDMF on PharmaCompass.

    Azilsartan Medoxomil JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Azilsartan Medoxomil Drug Master File in Japan (Azilsartan Medoxomil JDMF) empowers Azilsartan Medoxomil API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Azilsartan Medoxomil JDMF during the approval evaluation for pharmaceutical products. At the time of Azilsartan Medoxomil JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Azilsartan Medoxomil suppliers with JDMF on PharmaCompass.

    Azilsartan Medoxomil KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Azilsartan Medoxomil Drug Master File in Korea (Azilsartan Medoxomil KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Azilsartan Medoxomil. The MFDS reviews the Azilsartan Medoxomil KDMF as part of the drug registration process and uses the information provided in the Azilsartan Medoxomil KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Azilsartan Medoxomil KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Azilsartan Medoxomil API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Azilsartan Medoxomil suppliers with KDMF on PharmaCompass.

    Azilsartan Medoxomil WC

    A Azilsartan Medoxomil written confirmation (Azilsartan Medoxomil WC) is an official document issued by a regulatory agency to a Azilsartan Medoxomil manufacturer, verifying that the manufacturing facility of a Azilsartan Medoxomil active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Azilsartan Medoxomil APIs or Azilsartan Medoxomil finished pharmaceutical products to another nation, regulatory agencies frequently require a Azilsartan Medoxomil WC (written confirmation) as part of the regulatory process.

    click here to find a list of Azilsartan Medoxomil suppliers with Written Confirmation (WC) on PharmaCompass.

    Azilsartan Medoxomil NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Azilsartan Medoxomil as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Azilsartan Medoxomil API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Azilsartan Medoxomil as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Azilsartan Medoxomil and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Azilsartan Medoxomil NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Azilsartan Medoxomil suppliers with NDC on PharmaCompass.

    Azilsartan Medoxomil GMP

    Azilsartan Medoxomil Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Azilsartan Medoxomil GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Azilsartan Medoxomil GMP manufacturer or Azilsartan Medoxomil GMP API supplier for your needs.

    Azilsartan Medoxomil CoA

    A Azilsartan Medoxomil CoA (Certificate of Analysis) is a formal document that attests to Azilsartan Medoxomil's compliance with Azilsartan Medoxomil specifications and serves as a tool for batch-level quality control.

    Azilsartan Medoxomil CoA mostly includes findings from lab analyses of a specific batch. For each Azilsartan Medoxomil CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Azilsartan Medoxomil may be tested according to a variety of international standards, such as European Pharmacopoeia (Azilsartan Medoxomil EP), Azilsartan Medoxomil JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Azilsartan Medoxomil USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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