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Chemistry

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Also known as: 202409-33-4, Arcoxia, Tauxib, Nucoxia, Algix, Mk-0663
Molecular Formula
C18H15ClN2O2S
Molecular Weight
358.8  g/mol
InChI Key
MNJVRJDLRVPLFE-UHFFFAOYSA-N
FDA UNII
WRX4NFY03R

Etoricoxib
A sulfone and pyridine derivative that acts as a cyclooxygenase-2 inhibitor. It is used as a NSAID for the treatment of pain associated with RHEUMATOID ARTHRITIS and ANKYLOSING SPONDYLITIS. It is also used for the short-term treatment of moderate postoperative dental pain.
1 2D Structure

Etoricoxib

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine
2.1.2 InChI
InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3
2.1.3 InChI Key
MNJVRJDLRVPLFE-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=NC=C(C=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C
2.2 Other Identifiers
2.2.1 UNII
WRX4NFY03R
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Arcoxia

2. L 791456

3. L-791456

4. L791456

5. Mk 0663

6. Mk-0663

7. Mk0663

2.3.2 Depositor-Supplied Synonyms

1. 202409-33-4

2. Arcoxia

3. Tauxib

4. Nucoxia

5. Algix

6. Mk-0663

7. 5-chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-2,3'-bipyridine

8. Mk-663

9. L-791456

10. Mk 0663

11. 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine

12. Mk 663

13. 2,3'-bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-

14. 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine

15. Wrx4nfy03r

16. L791456

17. 5-chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine

18. Chebi:6339

19. Chembl416146

20. 2,3'-bipyridine, 5-chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-

21. 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine

22. Ncgc00164578-01

23. Etoricoxibe

24. Etropain

25. Torcoxia

26. Etoxib

27. 5-chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl

28. Mk-0663;l-791456

29. Dsstox_cid_26457

30. Dsstox_rid_81631

31. Dsstox_gsid_46457

32. Etoricoxib [usan:inn:ban]

33. Kingcox

34. 5-chloro-6'-methyl-3-(4-(methylsulfonyl)-phenyl)-2,3'-bipyridine

35. Etoricoxib [usan]

36. Cas-202409-33-4

37. Sr-05000001486

38. Etoricoxib (usan/inn)

39. Unii-wrx4nfy03r

40. Mk0663

41. Etoricoxibum

42. Etoricoxib- Bio-x

43. Etoricoxib [mi]

44. Etoricoxib [inn]

45. Etoricoxib [mart.]

46. Schembl4680

47. Etoricoxib [who-dd]

48. Gtpl2896

49. Dtxsid3046457

50. Hms2090a05

51. Hms3713p20

52. Hms3885h14

53. Zinc579472

54. Amy30994

55. Bcp06428

56. Ex-a2642

57. Tox21 112206

58. Tox21_112206

59. Bdbm50072064

60. Etoricoxib; Mk-663; Mk-0663

61. Mfcd06797512

62. S4651

63. Akos016010125

64. Tox21_112206_1

65. Ccg-220639

66. Cs-1047

67. Db01628

68. Sb18988

69. Ncgc00164578-02

70. 5ch

71. Ac-29052

72. As-17761

73. Bc164436

74. Etoricoxib 100 Microg/ml In Acetonitrile

75. Hy-15321

76. Db-045133

77. Ft-0602793

78. Ft-0668437

79. D03710

80. Etoricoxib, Vetranal(tm), Analytical Standard

81. Ab01275483-01

82. 409e334

83. A848896

84. L001141

85. Q631202

86. J-013140

87. Sr-05000001486-1

88. Sr-05000001486-2

89. Brd-k54770957-001-01-9

90. Brd-k54770957-001-02-7

91. L-791,456

92. F2173-0490

93. Etoricoxib, United States Pharmacopeia (usp) Reference Standard

94. 5-chloro-3-(4-methanesulfonyl-phenyl)-6''''-methyl-[2,3'''']bipyridinyl

95. 5-chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[2,3'']bipyridinyl

96. 5-chloro-3-(4-methanesulfonylphenyl)-2-(6-methylpyridin-3-yl)pyridine

97. 5-chloro-3-[4-(methylsulfonyl)phenyl]-2-(2-methyl-5-pyridinyl)pyridine

98. 5-chloro-6''-methyl-3-[4-(methylsulfonyl)phenyl]-2,3''-bipyridine

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 358.8 g/mol
Molecular Formula C18H15ClN2O2S
XLogP33.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass358.0542766 g/mol
Monoisotopic Mass358.0542766 g/mol
Topological Polar Surface Area68.3 Ų
Heavy Atom Count24
Formal Charge0
Complexity514
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.


5 Pharmacology and Biochemistry
5.1 Pharmacology

Etoricoxib is a COX-2 selective inhibitor (approximately 106 times more selective for COX-2 inhibition over COX-1).


5.2 MeSH Pharmacological Classification

Cyclooxygenase 2 Inhibitors

A subclass of cyclooxygenase inhibitors with specificity for CYCLOOXYGENASE-2. (See all compounds classified as Cyclooxygenase 2 Inhibitors.)


Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


5.3 ATC Code

M01AH05

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355


M - Musculo-skeletal system

M01 - Antiinflammatory and antirheumatic products

M01A - Antiinflammatory and antirheumatic products, non-steroids

M01AH - Coxibs

M01AH05 - Etoricoxib


5.4 Absorption, Distribution and Excretion

Absorption

Bioavailability is 100% following oral administration.


5.5 Metabolism/Metabolites

Hepatic, primarily via CYP3A4.


Etoricoxib has known human metabolites that include 6-Hydroxymethyletoricoxib and Etoricoxib 1'-N'-oxide.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


5.6 Biological Half-Life

22 hours


5.7 Mechanism of Action

Like any other COX-2 selective inhibitor Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2), preventing production of prostaglandins (PGs) from arachidonic acid.


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Zeon Pharma Industries India Pvt L...

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Emay Pharmaceuticals

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Gonane Pharma

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Octavius Pharma Pvt. Ltd

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Etoricoxib

About the Company : Zeon Pharma Industries India Pvt ltd is an ISO & GMP certified manufacturer of Bulk drugs & Intermediate and also supplies our associate manufacturing plant API / Semi finish form...

Zeon Pharma Industries India Pvt ltd is an ISO & GMP certified manufacturer of Bulk drugs & Intermediate and also supplies our associate manufacturing plant API / Semi finish formulations/Excipients, Phytochemicals/Enzymes & Intermediate and also has a GMP certified Manufacturing facility for Phytochemicals/Herbal extract and Enzymes through our associates.
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About the Company : Axplora, created from the merger of Farmabios, Novasep & PharmaZell, is a leading API manufacturing partner to the world’s leading pharma & biotech companies, delivering top-qual...

Axplora, created from the merger of Farmabios, Novasep & PharmaZell, is a leading API manufacturing partner to the world’s leading pharma & biotech companies, delivering top-quality APIs on time & at scale, to the highest industry standards. It is dedicated to helping pharma companies make critical medicines safely to benefit patients. Leveraging our combined expertise & manufacturing capabilities across 9 industrial sites in the EU & India & an R&D facility in the USA, it offers CDMO services for small molecule APIs & biopharmaceuticals to innovators as well as APIs that address lifestyle-induced respiratory, inflammatory & liver diseases.
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About the Company : LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, ...

LGM Pharma is a global leader in sourcing hard-to-find APIs and intermediates for the pharmaceutical and biotech industries. LGM is also a full service CDMO providing formulation, analytical method development and testing, and commercial manufacturing. LGM Pharma offers custom API synthesis, analytical development, and regulatory services. With a network of over 300 accredited CGMP manufacturing partners, LGM provides unparalleled supply chain security. And, with over 100,000 square feet of FDA-inspected cGMP manufacturing and warehouse capacity, LGM Pharma provides a one-stop solution for solid dose, powder, semi-solid and liquid drugs.
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Established in 2004, Metrochem API is one of the fastest-growing APIs, pellets & intermediates manufacturers. It has 6 dedicated manufacturing facilities for its 3 core product groups and has been approved by ISO 9001-2015, USFDA, WHO GMP, Cofepris & Japanese authorities. Metrochem’s in-depth industry knowledge, & hi-tech & advanced infrastructure, helps it provide quality products to its customers. Note: None of the products will be supplied to the countries where this could conflict with existing patents. Further, any products under patent will be offered for R&D purposes only. However, the final responsibility lies with the buyer
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About the Company : Established in 2012, Nuray Chemicals Pvt Ltd is an API manufacturer for highly regulated markets. Its manufacturing facility with state-of-the-art R&D is located near Chennai in th...

Established in 2012, Nuray Chemicals Pvt Ltd is an API manufacturer for highly regulated markets. Its manufacturing facility with state-of-the-art R&D is located near Chennai in the Indian state of Tamil Nadu. Nuray’s expertise and experience lie in developing the chemistry requirements of the pharmaceutical industry, including the synthesis of NCEs, impurities, metabolites, method development, advanced intermediates and APIs for commercial launch. With its focus on maintaining the highest levels of quality, reliability and transparency, Nuray has emerged as a trusted partner in the global generic market.
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About the Company : Emay Pharmaceuticals Pvt Ltd functions as the merchant export division of M/s. Bhavna Laboratories Pvt Ltd. As a GMP-approved API manufacturing company, we boast over three decades...

Emay Pharmaceuticals Pvt Ltd functions as the merchant export division of M/s. Bhavna Laboratories Pvt Ltd. As a GMP-approved API manufacturing company, we boast over three decades of experience in exporting a wide array of Pharmaceutical and allied products, engaging in both manufacturing and export operations. Emay Pharmaceuticals Pvt Ltd comprises a team of seasoned professionals with extensive expertise in Human Health APIs and Veterinary Health APIs. Specializing in the trade of various raw materials for both Human and Veterinary medicine, Emay Pharmaceuticals Pvt Ltd is dedicated to providing quality products.
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About the Company : Gonane Pharma, is a contract pharmaceutical company located in Gujarat, India, specializing in the manufacturing and marketing of Corticosteroids, Hormones, Antivirals, and Oncolog...

Gonane Pharma, is a contract pharmaceutical company located in Gujarat, India, specializing in the manufacturing and marketing of Corticosteroids, Hormones, Antivirals, and Oncology products. The company's core strength lies in its dedicated team, and its promoters bring over 25 years of experience in manufacturing, promoting products, and managing audits for regulated markets such as the EU, Mexico, China, Korea, and Russia. GONANE PHARMA is actively engaged in discussions with Japanese customers and anticipates further expansion into additional markets.
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About the Company : Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete ...

Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete sourcing solutions for pharmaceutical products from India, including technical and regulatory assistance. It believes in providing its customers with high-quality products at reasonable prices. It has always endeavored to achieve global standards in the field of pharmaceuticals and has carved out a niche for itself through new methods based on current market needs. Today, it has established itself as a truly global company, with exports to almost every continent.
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About the Company : Octavius Pharma is a global leader in Directly Compressible Granules with over 40 years of experience in Formulation development, manufacturing and commercialization. It offers a w...

Octavius Pharma is a global leader in Directly Compressible Granules with over 40 years of experience in Formulation development, manufacturing and commercialization. It offers a wide range of products such as tablets, capsules, syrups and ointments. Its portfolio includes finished dosage formulations, herbal/food supplements and APIs. It exports bulk drugs, finished formulations and APIs, while maintaining quality in compliance with WHO GMP norms. With an experienced team, Octavius Pharma provides consulting services for formulation development and marketing. Octavius exports to LATAM, Middle East, African, Asian and CIS countries.
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About the Company : Tenatra International was established as a proprietorship firm in 1999. It got off to a very good start, supporting clients in the United States, Mexico and Europe. As business opp...

Tenatra International was established as a proprietorship firm in 1999. It got off to a very good start, supporting clients in the United States, Mexico and Europe. As business opportunities grew, it was felt that the proprietorship firm had outlived its usefulness and that it needed a corporate structure. So, Tenatra Chemie Private Limited (TCPL) was incorporated in 2002. Since then, the company has come a long way, gaining valuable experience and knowledge in the fields of chemicals and pharmaceuticals in India.
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API Reference Price

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ORDER,","customerCountry":"SPAIN","quantity":"250.00","actualQuantity":"250","unit":"KGS","unitRateFc":"430","totalValueFC":"105611.6","currency":"USD","unitRateINR":36591.299119999996,"date":"28-Mar-2025","totalValueINR":"9147824.78","totalValueInUsd":"105611.6","indian_port":"Dahez-SEZ","hs_no":"29339990","bill_no":"9459861","productDescription":"API","marketType":"REGULATED MARKET","country":"SPAIN","selfForZScoreResived":"Pharma Grade","supplierPort":"Dahez-SEZ","supplierAddress":"PLOT 170-172, CHANDRAMOULI,INDUSTR, SOLAPUR,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1743100200,"product":"ETORICOXIB IH (PHARMACEUTICAL RAW MATERIAL)","address":"PLOT NO 983&984, SURVEY NO 163,,DH","city":"RANGAREDDY DISTRICT HYDERABAD,TELAN","supplier":"NEHA CHEMICALS","supplierCountry":"INDIA","foreign_port":"KARACHI","customer":"BANK AL HABIB ","customerCountry":"PAKISTAN","quantity":"50.00","actualQuantity":"50","unit":"KGS","unitRateFc":"94.8","totalValueFC":"4681.8","currency":"N\/A","unitRateINR":8110.6000000000004,"date":"28-Mar-2025","totalValueINR":"405530","totalValueInUsd":"4681.8","indian_port":"Hyderabad ICD","hs_no":"29339990","bill_no":"9445295","productDescription":"API","marketType":"","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad ICD","supplierAddress":"PLOT NO 983&984, SURVEY NO 163,,DH, RANGAREDDY DISTRICT HYDERABAD,TELAN","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1743186600,"product":"ETORICOXIB","address":"P No 257, 1st Floor","city":"KUKATPALLY,","supplier":"SAI SREYAS PHARMACEUTICAL PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"KARACHI -","customer":"MEEZAN BANK 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LTD.,","customerCountry":"GREECE","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"215","totalValueFC":"208277.6","currency":"N\/A","unitRateINR":18040.5,"date":"29-Mar-2025","totalValueINR":"18040500","totalValueInUsd":"208277.6","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"9517473","productDescription":"API","marketType":"REGULATED MARKET","country":"GREECE","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1743359400,"product":"ETORICOXIB IH","address":"02-35-73\/8, PLOT NO. 74,,SECTOR 10","city":"VISAKHAPATNAM,ANDHRA PRADESH","supplier":"ASSURGEN PHARMA","supplierCountry":"INDIA","foreign_port":"LAHORE","customer":"SHROOQ PHARMACEUTICALS PVT ","customerCountry":"PAKISTAN","quantity":"25.00","actualQuantity":"25","unit":"KGS","unitRateFc":"105","totalValueFC":"2582.6","currency":"N\/A","unitRateINR":8948,"date":"31-Mar-2025","totalValueINR":"223700","totalValueInUsd":"2582.6","indian_port":"Hyderabad Air","hs_no":"29333990","bill_no":"9563156","productDescription":"API","marketType":"","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"02-35-73\/8, PLOT NO. 74,,SECTOR 10, VISAKHAPATNAM,ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1743359400,"product":"ETORICOXIB","address":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N","city":"HYDERABAD,TELANGANA","supplier":"AURORE LIFE SCIENCES","supplierCountry":"INDIA","foreign_port":"JAKARTA","customer":"NOVELL PHARMACEUTICAL LABORATORIES","customerCountry":"INDONESIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"140","totalValueFC":"13295.2","currency":"N\/A","unitRateINR":11516,"date":"31-Mar-2025","totalValueINR":"1151600","totalValueInUsd":"13295.2","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"9561439","productDescription":"API","marketType":"","country":"INDONESIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1637951400,"product":"REIMPORT OF ETORICOXIB [SB NO:9809259 \/01.04.2021]","address":"JUBILEE HEIGHTS PLOT NO 68 & 69,2N D FLOOR SY NOS 66 & 67 MADHAPUR","city":"HYDERABAD,TELANGANA","supplier":"PHAROS LTD","supplierCountry":"INDIA","foreign_port":"NA","customer":"AURORE LIFE 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PHARMA","customerCountry":"INDIA","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"240","totalValueFC":"29417.3","currency":"USD","unitRateINR":"24520.5","date":"25-May-2024","totalValueINR":"2452054.5","totalValueInUsd":"29417.3","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"3665241","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGKOK","supplierAddress":"27\/26-27 SOIJARANSANITWONG 45ARUNAMARIN BANGKOKNOIBANGKOK 10700, THAILAND TH","customerAddress":"02-35-73\/8, PLOT NO. 74,,SECTOR 10"}]
01-Jan-2021
31-Mar-2025
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INTERMEDIATE SUPPLIERS

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01

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothZeon Pharma is a manufacturer and supplier of APIs & Intermediates.

CAS Number : 249561-98-6

End Use API : Etoricoxib

About The Company : Zeon Pharma Industries India Pvt ltd is an ISO & GMP certified manufacturer of Bulk drugs & Intermediate and also supplies our associate manufacturing plant API...

Zeon Pharma Industries India Pvt Ltd

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothZeon Pharma is a manufacturer and supplier of APIs & Intermediates.

CAS Number : 90536-66-6

End Use API : Etoricoxib

About The Company : Zeon Pharma Industries India Pvt ltd is an ISO & GMP certified manufacturer of Bulk drugs & Intermediate and also supplies our associate manufacturing plant API...

Zeon Pharma Industries India Pvt Ltd

03

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothZeon Pharma is a manufacturer and supplier of APIs & Intermediates.

CAS Number : 10297-73-1

End Use API : Etoricoxib

About The Company : Zeon Pharma Industries India Pvt ltd is an ISO & GMP certified manufacturer of Bulk drugs & Intermediate and also supplies our associate manufacturing plant API...

Zeon Pharma Industries India Pvt Ltd

04

Amara Labs

India
AAPS National Biotech
Not Confirmed
arrow

Amara Labs

India
AAPS National Biotech
Not Confirmed
arrow

CAS Number : 90536-66-6

End Use API : Etoricoxib

About The Company : Amara Labs Pvt Ltd is a WHO-GMP certified manufacturing company wholly owned by a team of technocrats with working experience of more than 20 years in Multi-Nat...

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05

Amara Labs

India
AAPS National Biotech
Not Confirmed
arrow

Amara Labs

India
AAPS National Biotech
Not Confirmed
arrow

CAS Number : 5470-70-2

End Use API : Etoricoxib

About The Company : Amara Labs Pvt Ltd is a WHO-GMP certified manufacturing company wholly owned by a team of technocrats with working experience of more than 20 years in Multi-Nat...

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06

Amara Labs

India
AAPS National Biotech
Not Confirmed
arrow

Amara Labs

India
AAPS National Biotech
Not Confirmed
arrow

CAS Number : 249561-98-6

End Use API : Etoricoxib

About The Company : Amara Labs Pvt Ltd is a WHO-GMP certified manufacturing company wholly owned by a team of technocrats with working experience of more than 20 years in Multi-Nat...

blank

07

Amara Labs

India
AAPS National Biotech
Not Confirmed
arrow

Amara Labs

India
AAPS National Biotech
Not Confirmed
arrow

CAS Number : 221615-75-4

End Use API : Etoricoxib

About The Company : Amara Labs Pvt Ltd is a WHO-GMP certified manufacturing company wholly owned by a team of technocrats with working experience of more than 20 years in Multi-Nat...

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08

AAPS National Biotech
Not Confirmed
arrow
AAPS National Biotech
Not Confirmed
arrow

CAS Number : 221615-75-4

End Use API : Etoricoxib

About The Company : Anupam Rasayan India Limited was started in 1976 and we are 36 years old. ISO 9001:2008 and ISO 14001:2004 certified chemical company with sound technology, en...

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09

AAPS National Biotech
Not Confirmed
arrow
AAPS National Biotech
Not Confirmed
arrow

CAS Number : 291756-76-8

End Use API : Etoricoxib

About The Company : Aptra Synthesis Private Limited, is a reliable and vertically integrated manufacturer of APIs and intermediates, boasting state-of-the-art manufacturing facilit...

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10

AAPS National Biotech
Not Confirmed
arrow
AAPS National Biotech
Not Confirmed
arrow

CAS Number : 90536-66-6

End Use API : Etoricoxib

About The Company : Aptra Synthesis Private Limited, is a reliable and vertically integrated manufacturer of APIs and intermediates, boasting state-of-the-art manufacturing facilit...

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ABOUT THIS PAGE

Looking for 202409-33-4 / Etoricoxib API manufacturers, exporters & distributors?

Etoricoxib manufacturers, exporters & distributors 1

12

PharmaCompass offers a list of Etoricoxib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Etoricoxib manufacturer or Etoricoxib supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Etoricoxib manufacturer or Etoricoxib supplier.

PharmaCompass also assists you with knowing the Etoricoxib API Price utilized in the formulation of products. Etoricoxib API Price is not always fixed or binding as the Etoricoxib Price is obtained through a variety of data sources. The Etoricoxib Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Etoricoxib

Synonyms

202409-33-4, Arcoxia, Tauxib, Nucoxia, Algix, Mk-0663

Cas Number

202409-33-4

Unique Ingredient Identifier (UNII)

WRX4NFY03R

About Etoricoxib

A sulfone and pyridine derivative that acts as a cyclooxygenase-2 inhibitor. It is used as a NSAID for the treatment of pain associated with RHEUMATOID ARTHRITIS and ANKYLOSING SPONDYLITIS. It is also used for the short-term treatment of moderate postoperative dental pain.

Arcoxia Manufacturers

A Arcoxia manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Arcoxia, including repackagers and relabelers. The FDA regulates Arcoxia manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Arcoxia API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Arcoxia manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Arcoxia Suppliers

A Arcoxia supplier is an individual or a company that provides Arcoxia active pharmaceutical ingredient (API) or Arcoxia finished formulations upon request. The Arcoxia suppliers may include Arcoxia API manufacturers, exporters, distributors and traders.

click here to find a list of Arcoxia suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Arcoxia USDMF

A Arcoxia DMF (Drug Master File) is a document detailing the whole manufacturing process of Arcoxia active pharmaceutical ingredient (API) in detail. Different forms of Arcoxia DMFs exist exist since differing nations have different regulations, such as Arcoxia USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Arcoxia DMF submitted to regulatory agencies in the US is known as a USDMF. Arcoxia USDMF includes data on Arcoxia's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Arcoxia USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Arcoxia suppliers with USDMF on PharmaCompass.

Arcoxia KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Arcoxia Drug Master File in Korea (Arcoxia KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Arcoxia. The MFDS reviews the Arcoxia KDMF as part of the drug registration process and uses the information provided in the Arcoxia KDMF to evaluate the safety and efficacy of the drug.

After submitting a Arcoxia KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Arcoxia API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Arcoxia suppliers with KDMF on PharmaCompass.

Arcoxia WC

A Arcoxia written confirmation (Arcoxia WC) is an official document issued by a regulatory agency to a Arcoxia manufacturer, verifying that the manufacturing facility of a Arcoxia active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Arcoxia APIs or Arcoxia finished pharmaceutical products to another nation, regulatory agencies frequently require a Arcoxia WC (written confirmation) as part of the regulatory process.

click here to find a list of Arcoxia suppliers with Written Confirmation (WC) on PharmaCompass.

Arcoxia NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Arcoxia as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Arcoxia API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Arcoxia as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Arcoxia and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Arcoxia NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Arcoxia suppliers with NDC on PharmaCompass.

Arcoxia GMP

Arcoxia Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Arcoxia GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Arcoxia GMP manufacturer or Arcoxia GMP API supplier for your needs.

Arcoxia CoA

A Arcoxia CoA (Certificate of Analysis) is a formal document that attests to Arcoxia's compliance with Arcoxia specifications and serves as a tool for batch-level quality control.

Arcoxia CoA mostly includes findings from lab analyses of a specific batch. For each Arcoxia CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Arcoxia may be tested according to a variety of international standards, such as European Pharmacopoeia (Arcoxia EP), Arcoxia JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Arcoxia USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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