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1. Ar 100
2. Ar-100
1. 192314-93-5
2. Ar-100
3. Mersarex
4. 5-[(2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-yl)methyl]pyrimidine-2,4-diamine
5. Ro-48-2622
6. 5-((2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-yl)methyl)pyrimidine-2,4-diamine
7. 42445huu0o
8. Ro-482622
9. Ar-100.001
10. Ro 63-9141;bal 9141
11. Ro 48-2622
12. Iclaprim [inn]
13. Ar-101
14. 2,4-pyrimidinediamine, 5-((2-cyclopropyl-7,8-dimethoxy-2h-1-benzopyran-5-yl)methyl)-
15. 2,4-pyrimidinediamine, 5-[(2-cyclopropyl-7,8-dimethoxy-2h-1-benzopyran-5-yl)methyl]-
16. Iclaprim [usan]
17. Iclaprim (usan/inn)
18. Iclaprim [usan:inn]
19. Unii-42445huu0o
20. Ar 100
21. Iclaprim [mi]
22. Iclaprim [mart.]
23. Iclaprim [who-dd]
24. 5-(2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-ylmethyl)-pyrimidine-2,4-diamine (iclaprim]
25. Schembl379386
26. Chembl134561
27. Schembl12899446
28. Bdbm18070
29. Gtpl10820
30. Dtxsid70870191
31. Chebi:131751
32. Hms3749a21
33. Bcp04499
34. Ar-100ar-100
35. Mfcd09837803
36. Cs-7873
37. Db06358
38. Sb17354
39. 5-((2rs)-2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-ylmethyl)pyrimidine-2,4-diamine
40. As-74032
41. Da-38934
42. Hy-101479
43. Ft-0670271
44. Ft-0670272
45. D08337
46. W16646
47. Q907480
48. J-012427
49. 5-(2-cyclopropyl-7,8-dimethoxy-2h-1-benzopyran-5-ylmethyl)pyrimidine-2,4-diamine
50. 5-[(2-cyclopropyl-7,8-dimethoxy-2h-1-benzopyran-5-yl)methyl]-2,4-pyrimidine- Diamine
51. 5-[(2-cyclopropyl-7,8-dimethoxy-2h-1-benzopyran-5-yl)methyl]pyrimidine-2,4-diamine
52. 5-[(2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-yl)methyl]pyrimidine-2,4- Diamine
53. 5-(((2rs)-2-cyclopropyl-7,8-dimethoxy-2h-1-benzopyran-5-yl)methyl)pyrimidine-2,4-diamine
| Molecular Weight | 354.4 g/mol |
|---|---|
| Molecular Formula | C19H22N4O3 |
| XLogP3 | 2.5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 5 |
| Exact Mass | 354.16919058 g/mol |
| Monoisotopic Mass | 354.16919058 g/mol |
| Topological Polar Surface Area | 106 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 515 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in bacterial infection, skin infections/disorders, obesity, liver disease, kidney disease, and pneumonia.
Folic Acid Antagonists
Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033) (See all compounds classified as Folic Acid Antagonists.)
J - Antiinfectives for systemic use
J01 - Antibacterials for systemic use
J01E - Sulfonamides and trimethoprim
J01EA - Trimethoprim and derivatives
J01EA03 - Iclaprim
Iclaprim is a novel diaminopyrimidine, and an inhibitor of dihydrofolate reductase, which has shown potent, extended-spectrum in vitro activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, vancomycin-intermediate and vancomycin-resistant S. aureus and macrolide-, quinolone- and trimethoprim-resistant strains. In addition, iclaprim has demonstrated activity against Streptococcus pneumoniae including penicillin-, erythromycin-, levofloxacin- and trimethoprim/sulfamethoxazole-resistant strains.
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PharmaCompass offers a list of AR-101 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right AR-101 manufacturer or AR-101 supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred AR-101 manufacturer or AR-101 supplier.
PharmaCompass also assists you with knowing the AR-101 API Price utilized in the formulation of products. AR-101 API Price is not always fixed or binding as the AR-101 Price is obtained through a variety of data sources. The AR-101 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A AR-101 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of AR-101, including repackagers and relabelers. The FDA regulates AR-101 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. AR-101 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A AR-101 supplier is an individual or a company that provides AR-101 active pharmaceutical ingredient (API) or AR-101 finished formulations upon request. The AR-101 suppliers may include AR-101 API manufacturers, exporters, distributors and traders.
AR-101 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of AR-101 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right AR-101 GMP manufacturer or AR-101 GMP API supplier for your needs.
A AR-101 CoA (Certificate of Analysis) is a formal document that attests to AR-101's compliance with AR-101 specifications and serves as a tool for batch-level quality control.
AR-101 CoA mostly includes findings from lab analyses of a specific batch. For each AR-101 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
AR-101 may be tested according to a variety of international standards, such as European Pharmacopoeia (AR-101 EP), AR-101 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (AR-101 USP).
