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Chemistry

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Also known as: Dl-amphetamine sulfate, Amphetamine sulphate, Phenaminum, 60-13-9, Amphamine sulfate, Amphetamini sulfas
Molecular Formula
C18H28N2O4S
Molecular Weight
368.5  g/mol
InChI Key
PYHRZPFZZDCOPH-UHFFFAOYSA-N
FDA UNII
6DPV8NK46S

Amphetamine
Amphetamine Sulfate is the sulfate salt form of amphetamine, a synthetic substance related to natural sympathomimetic amines. Amphetamine appears to exert its central nervous system (CNS) and peripheral effects indirectly by inducing the release of biogenic amines from their storage sites in nerve terminals. This agent is a commonly abused psychostimulant drug, which may be snorted, taken orally, smoked, or injected. Amphetamine induces psychologic dependence which is manifested by elevated mood, increased wakefulness, concentration, physical performance and a feeling of well-being. With sustained use, the effects of tachycardia and enhanced alertness diminish while psychotoxic effects such as hallucinations and delusions may occur. (NCI04)
1 2D Structure

Amphetamine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-phenylpropan-2-amine;sulfuric acid
2.1.2 InChI
InChI=1S/2C9H13N.H2O4S/c2*1-8(10)7-9-5-3-2-4-6-9;1-5(2,3)4/h2*2-6,8H,7,10H2,1H3;(H2,1,2,3,4)
2.1.3 InChI Key
PYHRZPFZZDCOPH-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(CC1=CC=CC=C1)N.CC(CC1=CC=CC=C1)N.OS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
6DPV8NK46S
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Dl-amphetamine Sulfate

2. Amphetamine Sulphate

3. Phenaminum

4. 60-13-9

5. Amphamine Sulfate

6. Amphetamini Sulfas

7. Dl-phenamine Sulfate

8. Dl-amphetamine Sulphate

9. Amphetaminium Sulfuricum

10. Desoxynorephedrine Sulfate

11. (+-)-amphetamine Sulfate

12. Dl-amphetamine Hydrogen Sulfate

13. (+-)-phenisopropylamine Sulfate

14. Amfetamine Sulfate

15. Amphetamine Sulfate [usp]

16. Dl-1-phenyl-2-aminopropane Sulfate

17. (+-)-2-amino-1-phenylpropane Sulfate

18. (+-)-alpha-methylphenethylamine Sulfate (2:1)

19. 6dpv8nk46s

20. 1-phenylpropan-2-amine Sulfate (2:1)

21. Amphetamine Sulfate (usp)

22. Fenopromin Sulfate

23. Penamine (van)

24. Ccris 3644

25. 1-phenyl-2-aminopropane Sulfate

26. Cerm 1767

27. Razemisches Phenylaminopropansulfat

28. Dl-alpha-methylphenethylamine Sulfate

29. Einecs 200-457-8

30. Unii-6dpv8nk46s

31. Nsc 170999

32. Dl-amphetamine Sulfate Salt

33. Benzadrine

34. Alpha-methylphenethylamine Sulfate, (+-)-

35. Benzedrine (tn)

36. Evekeo (tn)

37. Evekeo Odt

38. Rac-amphetamine Sulphate

39. D-amphetamine Sulfate Salt

40. Schembl41204

41. Amphetamine Sulfate [mi]

42. Dtxsid4020082

43. Phenethylamine, Alpha-methyl-, Sulfate (2:1), (+-)-

44. Chebi:51063

45. Amfetamine Sulfate [mart.]

46. Amphetamine Sulfate [vandf]

47. Amfetamine Sulfate [who-dd]

48. Bis{1-phenylpropan-2-amine} Sulfate

49. Amfetamine Sulfate [ep Impurity]

50. Amfetamine Sulfate [ep Monograph]

51. Amphetamine Sulfate [orange Book]

52. .beta.-phenylisopyropylaminesulfate

53. Benzeneethanamine, Alpha-methyl-, Sulfate

54. Amphetamine Sulfate [usp Monograph]

55. Amfetamine Sulfate [incb:green List]

56. Delcobese Component Amphetamine Sulfate

57. D02074

58. (+/-)-2-amino-1-phenylpropane Sulfate

59. (+/-)-2-amino-1-phenylpropane Sulphate

60. Amphetamine Sulfate Component Of Delcobese

61. Q21270844

62. (+/-)-.alpha.-methylphenethylamine Sulfate (2:1)

63. (+/-)-.alpha.-methylphenethylamine Sulphate (2:1)

64. Benzeneethanamine, .alpha.-methyl-, Sulfate (2:1), (+/-)-

65. Benzeneethanamine, .alpha.-methyl-, Sulphate (2:1), (+/-)-

66. Dl-amphetamine Sulfate Salt Solution, Drug Standard, 1.0 Mg/ml In Methanol

67. 2-(tetrahydro-furan-2-yl)-n-(3-trifluoromethyl-phenyl)-succinamicacid

68. 156-31-0

2.3.2 Other Synonyms

1. Amfetamine

2. Mydrial

3. Desoxynorephedrine

4. L Amphetamine

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 368.5 g/mol
Molecular Formula C18H28N2O4S
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass368.17697855 g/mol
Monoisotopic Mass368.17697855 g/mol
Topological Polar Surface Area135 Ų
Heavy Atom Count25
Formal Charge0
Complexity166
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3

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USDMF

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01

Veranova Lp

U.S.A
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33rd NZW-Hamburg
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothVeranova: A CDMO that manages complexity with confidence.

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Digital Content Digital Content

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 14783

Submission : 2000-03-17

Status : Active

Type : II

Veranova

02

Veranova Lp

U.S.A