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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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API Suppliers

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USDMF

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CEP/COS

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JDMF

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EU WC

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KDMF

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NDC API

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VMF

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0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

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FDA Orange Book

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Europe

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Canada

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Australia

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0 DRUGS IN DEVELOPMENT

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DRUG PRODUCT COMPOSITIONS

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0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

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US Patents

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US Exclusivities

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Health Canada Patents

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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API

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Chemistry

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Also known as: Isoamyl 4-methoxycinnamate, Isopentyl p-methoxycinnamate, Amiloxate [usan], Isoamyl methoxycinnamate, Amiloxato, Nsc-408332
Molecular Formula
C15H20O3
Molecular Weight
248.32  g/mol
InChI Key
UBNYRXMKIIGMKK-RMKNXTFCSA-N
FDA UNII
376KTP06K8

Amiloxate
AMILOXATE is a small molecule drug with a maximum clinical trial phase of II.
1 2D Structure

Amiloxate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-methylbutyl (E)-3-(4-methoxyphenyl)prop-2-enoate
2.1.2 InChI
InChI=1S/C15H20O3/c1-12(2)10-11-18-15(16)9-6-13-4-7-14(17-3)8-5-13/h4-9,12H,10-11H2,1-3H3/b9-6+
2.1.3 InChI Key
UBNYRXMKIIGMKK-RMKNXTFCSA-N
2.2 Other Identifiers
2.2.1 UNII
376KTP06K8
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Isoamyl 4-methoxycinnamate

2. Isopentyl P-methoxycinnamate

3. Amiloxate [usan]

4. Isoamyl Methoxycinnamate

5. Amiloxato

6. Nsc-408332

7. 376ktp06k8

8. Amiloxate [inn]

9. Amiloxate [mi]

10. E-1000

11. 4-methoxycinnamic Acid, Isoamyl Ester

12. Amiloxate [mart.]

13. Amiloxate [usp-rs]

14. Amiloxate [who-dd]

15. Amiloxate [usp Impurity]

16. Dtxcid9026055

17. Dtxsid1046055

18. Amiloxate [usp Monograph]

19. Nsc408332

20. Amiloxate (mart.)

21. Amiloxate (usp-rs)

22. 3-methylbutyl (2e)-3-(4-methoxyphenyl)prop-2-enoate

23. Amiloxate (usp Impurity)

24. Amiloxate (usp Monograph)

25. Amiloxatum

26. Refchem:557171

27. 2-propenoic Acid, 3-(4-methoxyphenyl)-, 3-methylbutyl Ester

28. Isopentyl 3-(4-methoxyphenyl)acrylate

29. Isopentyl-4-methoxycinnamate

30. Isopentyl 4-methoxycinnamate

31. Isoamyl-p-methoxycinnamate

32. 155339-66-5

33. 3-methylbutyl (e)-3-(4-methoxyphenyl)prop-2-enoate

34. Mfcd00583856

35. Ncgc00159435-02

36. 3-(4-methoxyphenyl)-2-propenoic Acid, 3-methylbutyl Ester

37. (e)-isopentyl 3-(4-methoxyphenyl)acrylate

38. 3-methylbutyl 3-(4-methoxyphenyl)prop-2-enoate

39. Neo Heliopan E1000

40. Amiloxate [usan:usp:inn]

41. Unii-376ktp06k8

42. Einecs 275-702-5

43. Neo Heliopan (tn)

44. Brn 3132627

45. Amiloxate (usp/inn)

46. Ai3-05552

47. 96% (isomers Mixture)

48. E 1000

49. Ec 275-702-5

50. 3-methylbutyl 3-(4-methoxyphenyl)-2-propenoate

51. Schembl15764

52. 3-10-00-00850 (beilstein Handbook Reference)

53. Chembl1476782

54. 3-(4-methoxyphenyl)-2-propenoic Acid 3-methylbutyl Ester

55. Msk3423

56. Chebi:135982

57. Ubnyrxmkiigmkk-rmknxtfcsa-n

58. Dtxsid301349309

59. 4-methoxycinnamic Acid-isoamyl Ester

60. Tox21_111666

61. S3218

62. Akos015913998

63. Akos025310783

64. Cs-w012670

65. Db11207

66. Fi29838

67. Hy-w011954

68. Nsc 408332

69. Ncgc00159435-03

70. Bs-49548

71. Da-54393

72. Cas-71617-10-2

73. D02904

74. D91203

75. Isoamyl 4-methoxycinnamate, Analytical Standard

76. Sbi-0654197.0001

77. En300-7363198

78. Isopentyl (e)-3-(4-methoxyphenyl)prop-2-enoate

79. 617i102

80. En300-18004835

81. Sr-01000201509

82. Sr-01000201509-1

83. 3-(4-methoxyphenyl)-2-propenoic Acid, Isoamyl Ester

84. 3-methylbutyl (2e)-3-(4-methoxyphenyl)-2-propenoate

85. Brd-k37851352-001-01-0

86. Q17012246

87. Z212714982

88. Amiloxate, United States Pharmacopeia (usp) Reference Standard

89. 2-benzoic Acid, 2-propenoic Acid, 3-(4-methoxyphenyl)-3-methylbutyl Ester

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 248.32 g/mol
Molecular Formula C15H20O3
XLogP33.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count7
Exact Mass Da
Monoisotopic Mass Da
Topological Polar Surface Area35.5
Heavy Atom Count18
Formal Charge0
Complexity263
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Indicated as an active sunscreen agent.


5 Pharmacology and Biochemistry
5.1 Absorption, Distribution and Excretion

Absorption

According to _in vitro_ studies of amiloxate-containing tape strips on porcine ear, there was no detection of amiloxate undergoing skin penetration.


Route of Elimination

No pharmacokinetic data available.


Volume of Distribution

No pharmacokinetic data available.


Clearance

No pharmacokinetic data available.


5.2 Metabolism/Metabolites

No pharmacokinetic data available.


5.3 Biological Half-Life

No pharmacokinetic data available.


5.4 Mechanism of Action

Amiloxate is a UV-B filter that selectively absorbs UV-B rays. It is proposed that amiloxate mediates an antioxidant action by acting as a free radical scavenger.


REF. STANDARDS & IMPURITIES

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Looking for 71617-10-2 / Amiloxate API manufacturers, exporters & distributors?

Amiloxate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Amiloxate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Amiloxate manufacturer or Amiloxate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Amiloxate manufacturer or Amiloxate supplier.

API | Excipient name

Amiloxate

Synonyms

Isoamyl 4-methoxycinnamate, Isopentyl p-methoxycinnamate, Amiloxate [usan], Isoamyl methoxycinnamate, Amiloxato, Nsc-408332

Cas Number

71617-10-2

Unique Ingredient Identifier (UNII)

376KTP06K8

About Amiloxate

AMILOXATE is a small molecule drug with a maximum clinical trial phase of II.

Amiloxate Manufacturers

A Amiloxate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Amiloxate, including repackagers and relabelers. The FDA regulates Amiloxate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Amiloxate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Amiloxate Suppliers

A Amiloxate supplier is an individual or a company that provides Amiloxate active pharmaceutical ingredient (API) or Amiloxate finished formulations upon request. The Amiloxate suppliers may include Amiloxate API manufacturers, exporters, distributors and traders.

Amiloxate GMP

Amiloxate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Amiloxate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Amiloxate GMP manufacturer or Amiloxate GMP API supplier for your needs.

Amiloxate CoA

A Amiloxate CoA (Certificate of Analysis) is a formal document that attests to Amiloxate's compliance with Amiloxate specifications and serves as a tool for batch-level quality control.

Amiloxate CoA mostly includes findings from lab analyses of a specific batch. For each Amiloxate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Amiloxate may be tested according to a variety of international standards, such as European Pharmacopoeia (Amiloxate EP), Amiloxate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Amiloxate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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