Alpharma Brand of Trimetazidine Dihydrochloride

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Also known as: 13171-25-0, 1-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride, Trimetazidine hydrochloride, Kyurinett, Trimetazidine hcl, Trimetazidine 2hcl

Molecular Formula

C₁₄H₂₄Cl₂N₂O₃

Molecular Weight

339.3 g/mol

InChI Key

VYFLPFGUVGMBEP-UHFFFAOYSA-N

FDA UNII

48V6723Z1P

A vasodilator used in angina of effort or ischemic heart disease.

1 2D Structure

Alpharma Brand of Trimetazidine Dihydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride

2.1.2 InChI

InChI=1S/C14H22N2O3.2ClH/c1-17-12-5-4-11(13(18-2)14(12)19-3)10-16-8-6-15-7-9-16;;/h4-5,15H,6-10H2,1-3H3;2*1H

2.1.3 InChI Key

VYFLPFGUVGMBEP-UHFFFAOYSA-N

2.1.4 Canonical SMILES

COC1=C(C(=C(C=C1)CN2CCNCC2)OC)OC.Cl.Cl

2.2 Other Identifiers

2.2.1 UNII

48V6723Z1P

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Centrophne

2. Dihydrochloride, Trimetazidine

3. Idaptan

4. Trimtazidine Irex

5. Trimetazidine

6. Vasartel

7. Vastarel

2.3.2 Depositor-Supplied Synonyms

1. 13171-25-0

2. 1-(2,3,4-trimethoxybenzyl)piperazine Dihydrochloride

3. Trimetazidine Hydrochloride

4. Kyurinett

5. Trimetazidine Hcl

6. Trimetazidine 2hcl

7. Trimetazidine (dihydrochloride)

8. Yoshimilon

9. Vastarel F

10. 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine Dihydrochloride

11. Trimetazidine Di-hcl

12. Trimetazidine Hydrochloride [jan]

13. Trimetazidine Dihcl

14. Trimethazidine Dihydrochloride

15. Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-, Dihydrochloride

16. Mfcd00243086

17. 48v6723z1p

18. Nsc-759317

19. Trimetajust

20. Lubomail

21. Vastarel

22. Yosimilon

23. Piperazine, 1-((2,3,4-trimethoxyphenyl)methyl)-, Dihydrochloride

24. Dsstox_cid_25407

25. Dsstox_rid_80858

26. Dsstox_gsid_45407

27. 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride

28. Adexor

29. Piperazine, 1-((2,3,4-trimethoxyphenyl)methyl)-, Dihydrochloride (9ci)

30. Sr-01000781912

31. Ncgc00016697-01

32. Einecs 236-117-0

33. Cas-13171-25-0

34. Unii-48v6723z1p

35. S 4004

36. Kyurinett (tn)

37. Prestwick_871

38. Schembl580378

39. Chembl3561076

40. Dtxsid1045407

41. Chebi:32262

42. Piperazine, 1-(2,3,4-trimethoxybenzyl)-, Dihydrochloride

43. Hms1569n19

44. Bcp21402

45. Hy-b0968

46. Trimetazidine For System Suitability

47. Trimetazidine Hydrochloride (jp17)

48. Tox21_110568

49. S4543

50. Akos015895369

51. Tox21_110568_1

52. Ab05480

53. Ac-5896

54. Ccg-213960

55. Cs-4453

56. Ks-1125

57. Nsc 759317

58. Ncgc00016697-04

59. Trimetazidine Dihydrochloride [mi]

60. Trimetazidine Hydrochloride [mart.]

61. Trimetazidine Hydrochloride [who-dd]

62. Ft-0630397

63. T2726

64. A25088

65. D01606

66. P10117

67. 2,3,4-trimethoxybenzylpiperazine Dihydrochloride

68. 171t250

69. Sr-01000781912-3

70. Sr-01000781912-4

71. Trimetazidine Dihydrochloride [ep Monograph]

72. W-108326

73. 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine Dihcl

74. Q27259190

75. F2173-1142

76. 1-(2,3,4-trimethoxybenzyl)piperazine Dihydrochloride, 97%

77. Trimetazidine Dihydrochloride 1.0 Mg/ml In Methanol (as Free Base)

78. Trimetazidine For System Suitability, European Pharmacopoeia (ep) Reference Standard

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₁₄H₂₄Cl₂N₂O₃
Molecular Weight	339.3 g/mol
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	338.1163980 g/mol
Monoisotopic Mass	338.1163980 g/mol
Topological Polar Surface Area	43 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	259
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3