Alclometasone Dipropionate

Synopsis, Chemistry

APIs // Active Pharmaceutical Ingredients

4 API Suppliers, 3 USDMF, 1 JDMF, 2 NDC API, 3 Listed Suppliers

PRICE INFORMATION

API Reference Price, API Exports, API Imports

DOSSIERs // Finished Dosage Formulations

10 Dossiers, 8 FDA Orange Book, 2 Listed Dossiers

RELATED EXCIPIENT COMPANIES

Suppliers, 8 BASF, 5 Kerry, 1 Nanjing Well Pharmaceutical, 1 Finar, 1 Seppic

EXCIPIENTS BY APPLICATIONS

9 Topical, 5 Co-Processed Excipients, 4 Thickeners and Stabilizers, 2 Film Formers & Plasticizers, 2 Solubilizers, 1 Lubricants & Glidants, 1 Granulation, 1 Fillers, Diluents & Binders, 1 Direct Compression, 1 Coating Systems & Additives, 1 Emulsifying Agents, 1 Parenteral

GLOBAL SALES INFORMATION

8 US Medicaid Prescriptions, 3 Finished Drug Prices

MARKET PLACE

1 APIs

1 APIs

ANALYTICAL SOLUTION(s)

2 USP Standards, 2 Other Ref. Standards

Product Search

API SUPPLIERS

API Suppliers

US DMFs Filed

CEP/COS Certifications

JDMFs Filed

Other Certificates

Other Suppliers

API REF. PRICE (USD / KG)

131,370

API Market Place

INTERMEDIATES

DOSSIERS // FDF

USA (Orange Book)

Europe

Canada

Australia

South Africa

Uploaded Dossiers

GLOBAL SALES (USD Million)

U.S. Medicaid

27.00

Annual Reports

FDF Market Place

EXCIPIENTS

PATENTS & EXCLUSIVITIES

USFDA Orange Book Patents

USFDA Exclusivities

DIGITAL CONTENT

Blog #PharmaFlow

News

REF STANDARD

EDQM

USP

Other Listed Suppliers

SERVICES

Also known as: Mls002153993, Prestwick0_000771, Prestwick1_000771, Prestwick2_000771, Prestwick3_000771, Bspbio_000842

Molecular Formula

C₂₈H₃₇ClO₇

Molecular Weight

521.0 g/mol

InChI Key

DJHCCTTVDRAMEH-LSTGEUPGSA-N

1 2D Structure

Alclometasone Dipropionate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

[2-[(7R,8S,9S,10R,11S,13S,14S,16R)-7-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate

2.1.2 InChI

InChI=1S/C28H37ClO7/c1-6-22(33)35-14-21(32)28(36-23(34)7-2)15(3)10-18-24-19(29)12-16-11-17(30)8-9-26(16,4)25(24)20(31)13-27(18,28)5/h8-9,11,15,18-20,24-25,31H,6-7,10,12-14H2,1-5H3/t15-,18+,19-,20+,24-,25+,26+,27+,28?/m1/s1

2.1.3 InChI Key

DJHCCTTVDRAMEH-LSTGEUPGSA-N

2.1.4 Canonical SMILES

CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3C2C(CC4=CC(=O)C=CC34C)Cl)O)C)C)OC(=O)CC

2.1.5 Isomeric SMILES

CCC(=O)OCC(=O)C1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2[C@@H](CC4=CC(=O)C=C[C@]34C)Cl)O)C)C)OC(=O)CC

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Mls002153993

2. Prestwick0_000771

3. Prestwick1_000771

4. Prestwick2_000771

5. Prestwick3_000771

6. Bspbio_000842

7. Spbio_002781

8. Bpbio1_000928

9. Chembl1377952

10. Schembl13985345

11. Hms1570k04

12. Hms2097k04

13. Hms2230e23

14. Hms3714k04

15. Ccg-220771

16. Ncgc00179403-01

17. Smr001233327

18. Ab00513918

19. Brd-a74610643-001-03-1

2.3 Create Date

2006-06-05

3 Chemical and Physical Properties

Molecular Formula	C₂₈H₃₇ClO₇
Molecular Weight	521.0 g/mol
XLogP3	3.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	8
Exact Mass	520.2227812 g/mol
Monoisotopic Mass	520.2227812 g/mol
Topological Polar Surface Area	107 Å²
Heavy Atom Count	36
Formal Charge	0
Complexity	1030
Isotope Atom Count	0
Defined Atom Stereocenter Count	8
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Alclometasone dipropionate
Drug Label	Alclometasone dipropionate ointment contains alclometasone dipropionate (7-chloro-11 ,17,21-trihydroxy-16 -methylpregna-1,4-diene-3,20-dione 17,21-dipropionate), a synthetic corticosteroid for topical dermatologic use. The corticosteroids const...
Active Ingredient	Alclometasone dipropionate
Dosage Form	Ointment; Cream
Route	Topical
Strength	0.05%
Market Status	Prescription
Company	Glenmark Generics; Fougera Pharms; Taro

2 of 2
Drug Name	Alclometasone dipropionate
Drug Label	Alclometasone dipropionate ointment contains alclometasone dipropionate (7-chloro-11 ,17,21-trihydroxy-16 -methylpregna-1,4-diene-3,20-dione 17,21-dipropionate), a synthetic corticosteroid for topical dermatologic use. The corticosteroids const...
Active Ingredient	Alclometasone dipropionate
Dosage Form	Ointment; Cream
Route	Topical
Strength	0.05%
Market Status	Prescription
Company	Glenmark Generics; Fougera Pharms; Taro